Cryptococcus neoformans phospholipase B1 activates host cell Rac1 for traversal across the blood-brain barrier

scientific article

Cryptococcus neoformans phospholipase B1 activates host cell Rac1 for traversal across the blood-brain barrier is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1111/J.1462-5822.2012.01819.X
P932PMC publication ID3443264
P698PubMed publication ID22646320
P5875ResearchGate publication ID225079918

P50authorJohn R PerfectQ64932411
Ravi MaruvadaQ82192253
P2093author name stringKyung J Kwon-Chung
Yi Zheng
Kwang Sik Kim
Donna Pearce
Longkun Zhu
P2860cites workA Ras1-Cdc24 signal transduction pathway mediates thermotolerance in the fungal pathogen Cryptococcus neoformansQ62623721
Infections with Cryptococcus neoformans in the acquired immunodeficiency syndromeQ69532023
CryptococcosisQ78746513
The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformansQ22065807
Rho GTPases and the actin cytoskeletonQ27860579
Regulation of STAT3 by direct binding to the Rac1 GTPaseQ28140511
Clinical presentation, natural history, and cumulative death rates of 230 adults with primary cryptococcal meningitis in Zambian AIDS patients treated under local conditionsQ28365296
Rational design and characterization of a Rac GTPase-specific small molecule inhibitorQ29616494
Real-time imaging of trapping and urease-dependent transmigration of Cryptococcus neoformans in mouse brain.Q30494253
Mechanism of Shigella entry into epithelial cellsQ33536573
Phospholipids trigger Cryptococcus neoformans capsular enlargement during interactions with amoebae and macrophages.Q33921260
Arachidonic acid metabolism regulates Escherichia coli penetration of the blood-brain barrierQ34177395
Capsule structure changes associated with Cryptococcus neoformans crossing of the blood-brain barrierQ35083658
Urease expression by Cryptococcus neoformans promotes microvascular sequestration, thereby enhancing central nervous system invasionQ35098130
Aetiology of meningitis in HIV-infected patients in a referral hospital in Phnom Penh, CambodiaQ35652228
IbeA and OmpA of Escherichia coli K1 exploit Rac1 activation for invasion of human brain microvascular endothelial cellsQ36018207
Striking a balance: modulation of the actin cytoskeleton by SalmonellaQ36105372
Deciphering the model pathogenic fungus Cryptococcus neoformansQ36244884
Mechanisms of microbial traversal of the blood-brain barrierQ37208293
Cryptococcal yeast cells invade the central nervous system via transcellular penetration of the blood-brain barrierQ37521730
Cryptococcal infection in a cohort of HIV-1-infected Ugandan adultsQ38884510
Differential Ca2+ signaling by thrombin and protease-activated receptor-1-activating peptide in human brain microvascular endothelial cellsQ39658447
Cell-cell junctions of dermal microvascular endothelial cells contain tight and adherens junction proteins in spatial proximityQ40560123
Extracellular phospholipase activity is a virulence factor for Cryptococcus neoformansQ40836371
Wsp1 is downstream of Cin1 and regulates vesicle transport and actin cytoskeleton as an effector of Cdc42 and Rac1 in Cryptococcus neoformansQ42088045
A Rac homolog functions downstream of Ras1 to control hyphal differentiation and high-temperature growth in the pathogenic fungus Cryptococcus neoformansQ42152803
Pathology of cryptococcal meningoencephalitis: analysis of 27 patients with pathogenetic implicationsQ44781962
Impact of HIV infection on meningitis in Harare, Zimbabwe: a prospective study of 406 predominantly adult patientsQ46410272
Pathogenesis of cerebral Cryptococcus neoformans infection after fungemiaQ48500734
RhoA and Rac1 contribute to type III group B streptococcal invasion of human brain microvascular endothelial cellsQ48550784
Selective expression of adhesion molecules on human brain microvascular endothelial cellsQ48697836
Bacterial meningitis in Malawian adults: pneumococcal disease is common, severe, and seasonal.Q54043087
P433issue10
P921main subjectCryptococcus neoformansQ131924
blood–brain barrierQ221694
P304page(s)1544-1553
P577publication date2012-06-26
P1433published inCellular MicrobiologyQ1921948
P1476titleCryptococcus neoformans phospholipase B1 activates host cell Rac1 for traversal across the blood-brain barrier
P478volume14

Reverse relations

cites work (P2860)
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Q36332842Cryptococcus neoformans activates RhoGTPase proteins followed by protein kinase C, focal adhesion kinase, and ezrin to promote traversal across the blood-brain barrier
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Q37092831Two Rac paralogs regulate polarized growth in the human fungal pathogen Cryptococcus neoformans

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