Cryptococcal Meningitis and Anti-virulence Therapeutic Strategies

scientific article published in 2019

Cryptococcal Meningitis and Anti-virulence Therapeutic Strategies is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FMICB.2019.00353
P932PMC publication ID6399105
P698PubMed publication ID30863389

P2093author name stringAngie Gelli
Kiem Vu
Javier A Garcia
P2860cites workThe Cryptococcus neoformans capsule: a sword and a shieldQ24619875
Flucytosine and cryptococcosis: time to urgently address the worldwide accessibility of a 50-year-old antifungalQ27012487
Synergistic combinations of antifungals and anti-virulence agents to fight against Candida albicansQ28082407
Mechanisms and functions of Eph and ephrin signallingQ28208291
Cryptococcus neoformans resides in an acidic phagolysosome of human macrophagesQ28295002
Increased permeability of blood-brain barrier is mediated by serine protease during Cryptococcus meningitisQ28305427
Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDSQ29617372
Eph receptor signalling casts a wide net on cell behaviourQ29619988
Cryptococcal meningitis.Q54075694
Antifungal Combinations for Treatment of Cryptococcal Meningitis in Africa.Q54255992
Arylamino containing hydroxamic acids as potent urease inhibitors for the treatment of Helicobacter pylori infectionQ57091995
Flurofamide: a potent inhibitor of bacterial urease with potential clinical utility in the treatment of infection induced urinary stonesQ70220406
The capsule of cryptococcus neoformans passively inhibits phagocytosis of the yeast by macrophagesQ70254971
Treatment with monoclonal antibodies against Clostridium difficile toxinsQ84070721
Fungal infections of the central nervous systemQ86996872
The Early Innate Immune Response to, and Phagocyte-Dependent Entry of, Cryptococcus neoformans Map to the Perivascular Space of Cortical Post-Capillary Venules in NeurocryptococcosisQ89180669
Cryptococcal transmigration across a model brain blood-barrier: evidence of the Trojan horse mechanism and differences between Cryptococcus neoformans var. grubii strain H99 and Cryptococcus gattii strain R265.Q38835353
Different drugs for bad bugs: antivirulence strategies in the age of antibiotic resistanceQ39197564
Global burden of disease of HIV-associated cryptococcal meningitis: an updated analysisQ39379643
1,2-Benzisoselenazol-3(2H)-one Derivatives As a New Class of Bacterial Urease InhibitorsQ40576160
EphrinA1-induced cytoskeletal re-organization requires FAK and p130(cas).Q40716314
Microvilli-like structures are associated with the internalization of virulent capsulated Neisseria meningitidis into vascular endothelial cells.Q40745925
Cryptococcus neoformans promotes its transmigration into the central nervous system by inducing molecular and cellular changes in brain endothelial cellsQ41886935
Astrocytic tight junctions control inflammatory CNS lesion pathogenesisQ42644144
The Human Blood-Brain Barrier Internalizes Cryptococcus neoformans via the EphA2-Tyrosine Kinase Receptor.Q46361858
Involvement of human CD44 during Cryptococcus neoformans infection of brain microvascular endothelial cellsQ46481054
Development of Anti-Virulence Approaches for Candidiasis via a Novel Series of Small-Molecule Inhibitors of Candida albicans FilamentationQ47189974
Ephrin receptor A2 is a functional entry receptor for Epstein-Barr virus.Q47559100
Discovery of a Novel Dibromoquinoline Compound Exhibiting Potent Antifungal and Antivirulence Activity That Targets Metal Ion HomeostasisQ48164716
Cryptococcus neoformans induces alterations in the cytoskeleton of human brain microvascular endothelial cellsQ48177549
Pathogenesis of cerebral Cryptococcus neoformans infection after fungemiaQ48500734
An expanded family of fungalysin extracellular metallopeptidases of Coprinopsis cinerea.Q53495009
Malaria parasites target the hepatocyte receptor EphA2 for successful host infectionQ30047034
Approval of Raxibacumab for the Treatment of Inhalation Anthrax Under the US Food and Drug Administration "Animal Rule".Q30201937
Cryptococcal meningitis: epidemiology, immunology, diagnosis and therapyQ30240687
Replication of Cryptococcus neoformans in macrophages is accompanied by phagosomal permeabilization and accumulation of vesicles containing polysaccharide in the cytoplasmQ30476172
Real-time imaging of trapping and urease-dependent transmigration of Cryptococcus neoformans in mouse brain.Q30494253
Invasion of the central nervous system by Cryptococcus neoformans requires a secreted fungal metalloprotease.Q33724907
The Metalloprotease, Mpr1, Engages AnnexinA2 to Promote the Transcytosis of Fungal Cells across the Blood-Brain BarrierQ33857975
Laccase of Cryptococcus neoformans is a cell wall-associated virulence factorQ34008955
Immune modulation mediated by cryptococcal laccase promotes pulmonary growth and brain dissemination of virulent Cryptococcus neoformans in mice.Q34460637
Human botulism immune globulin for the treatment of infant botulismQ34490632
How do extracellular pathogens cross the blood-brain barrier?Q34522621
Phagosome extrusion and host-cell survival after Cryptococcus neoformans phagocytosis by macrophagesQ34579227
CPS1, a homolog of the Streptococcus pneumoniae type 3 polysaccharide synthase gene, is important for the pathobiology of Cryptococcus neoformansQ34720974
Evidence of a role for monocytes in dissemination and brain invasion by Cryptococcus neoformansQ34860542
Urease expression by Cryptococcus neoformans promotes microvascular sequestration, thereby enhancing central nervous system invasionQ35098130
Evaluation of a newly developed lateral flow immunoassay for the diagnosis of cryptococcosisQ35141239
The emerging role of urease as a general microbial virulence factorQ35169182
4-methylumbelliferone treatment and hyaluronan inhibition as a therapeutic strategy in inflammation, autoimmunity, and cancerQ35206080
EphrinA2 receptor (EphA2) is an invasion and intracellular signaling receptor for Chlamydia trachomatisQ35533099
Quorum quenching quandary: resistance to antivirulence compoundsQ35758927
Hyaluronic acid receptor CD44 deficiency is associated with decreased Cryptococcus neoformans brain infectionQ35939738
Identification and characterization of CPS1 as a hyaluronic acid synthase contributing to the pathogenesis of Cryptococcus neoformans infectionQ35947140
Cryptococcus neoformans phospholipase B1 activates host cell Rac1 for traversal across the blood-brain barrierQ36236518
Cryptococcus neoformans activates RhoGTPase proteins followed by protein kinase C, focal adhesion kinase, and ezrin to promote traversal across the blood-brain barrierQ36332842
Role of extracellular phospholipases and mononuclear phagocytes in dissemination of cryptococcosis in a murine modelQ37116098
Invasion of Cryptococcus neoformans into human brain microvascular endothelial cells requires protein kinase C-alpha activationQ37312232
The capsule of the fungal pathogen Cryptococcus neoformansQ37337879
Immortalized human brain endothelial cell line HCMEC/D3 as a model of the blood-brain barrier facilitates in vitro studies of central nervous system infection by Cryptococcus neoformansQ37410097
Cryptococcal yeast cells invade the central nervous system via transcellular penetration of the blood-brain barrierQ37521730
Trojan Horse Transit Contributes to Blood-Brain Barrier Crossing of a Eukaryotic Pathogen.Q37617655
Targeting Candida albicans filamentation for antifungal drug development.Q37705311
Advanced HIV disease in Botswana following successful antiretroviral therapy rollout: Incidence of and temporal trends in cryptococcal meningitis.Q38785746
Obiltoxaximab: First Global ApprovalQ38809942
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectmeningitisQ48143
Cryptococcus neoformansQ131924
cryptococcal meningitisQ18967011
P304page(s)353
P577publication date2019-01-01
P1433published inFrontiers in MicrobiologyQ27723481
P1476titleCryptococcal Meningitis and Anti-virulence Therapeutic Strategies
P478volume10

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cites work (P2860)
Q92420896Central Nervous System Cryptococcal Infections in Non-HIV Infected Patients
Q91644191The cAMP/Protein Kinase a Pathway Regulates Virulence and Adaptation to Host Conditions in Cryptococcus neoformans

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