Assessing fear and anxiety in humans using the threat of predictable and unpredictable aversive events (the NPU-threat test)

scientific article

Assessing fear and anxiety in humans using the threat of predictable and unpredictable aversive events (the NPU-threat test) is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/NPROT.2012.001
P2888exact matchhttps://scigraph.springernature.com/pub.10.1038/nprot.2012.001
P932PMC publication ID3446242
P698PubMed publication ID22362158
P5875ResearchGate publication ID221858465

P2093author name stringChristian Grillon
Anja Schmitz
P2860cites workMeasuring anxious responses to predictable and unpredictable threat in children and adolescentsQ30463010
Alcohol stress response dampening: selective reduction of anxiety in the face of uncertain threatQ30464860
Does intolerance of uncertainty predict anticipatory startle responses to uncertain threat?Q30465172
Phasic and sustained fear are pharmacologically dissociable in ratsQ30466236
Effects of predictability of shock timing and intensity on aversive responsesQ30468034
Nicotine withdrawal increases threat-induced anxiety but not fear: neuroadaptation in human addiction.Q30473722
Acute hydrocortisone treatment increases anxiety but not fear in healthy volunteers: a fear-potentiated startle studyQ30475110
Phasic vs sustained fear in rats and humans: role of the extended amygdala in fear vs anxietyQ30477934
Increased anxiety during anticipation of unpredictable aversive stimuli in posttraumatic stress disorder but not in generalized anxiety disorder.Q30480711
Alcohol selectively reduces anxiety but not fear: startle response during unpredictable versus predictable threatQ30486203
Greater sustained anxiety but not phasic fear in women compared to men.Q30490139
Two-week treatment with the selective serotonin reuptake inhibitor citalopram reduces contextual anxiety but not cued fear in healthy volunteers: a fear-potentiated startle studyQ30491012
Unraveling the mysteries of anxiety and its disorders from the perspective of emotion theoryQ33940803
Role of the bed nucleus of the stria terminalis versus the amygdala in fear, stress, and anxietyQ35071515
Increased anxiety during anticipation of unpredictable but not predictable aversive stimuli as a psychophysiologic marker of panic disorder.Q37159913
Contextual conditioning in rats as an animal model for generalized anxiety disorderQ37837718
Context conditioning and behavioral avoidance in a virtual reality environment: effect of predictability.Q40291528
Anxious responses to predictable and unpredictable aversive events.Q40472919
Defense system psychopharmacology: an ethological approach to the pharmacology of fear and anxietyQ40621783
The structure of common mental disordersQ44243916
Lesions in the bed nucleus of the stria terminalis disrupt corticosterone and freezing responses elicited by a contextual but not by a specific cue-conditioned fear stimulusQ45079653
Effects of bed nucleus of the stria terminalis lesions on conditioned anxiety: aversive conditioning with long-duration conditional stimuli and reinstatement of extinguished fear.Q48526133
The benzodiazepine alprazolam dissociates contextual fear from cued fear in humans as assessed by fear-potentiated startle.Q48572952
Contextual fear induced by unpredictability in a human fear conditioning preparation is related to the chronic expectation of a threatening US.Q50884609
A single dose of the selective serotonin reuptake inhibitor citalopram exacerbates anxiety in humans: a fear-potentiated startle study.Q50925503
Structure of anxiety and the anxiety disorders: a hierarchical model.Q51114568
ANXIETY: REIFICATION OF A METAPHOR.Q51352124
Posttraumatic stress disorder and the structure of common mental disorders.Q51955369
Background Stimuli and the Inter-Stimulus Interval during Pavlovian ConditioningQ52312220
Structural relationships among dimensions of the DSM-IV anxiety and mood disorders and dimensions of negative affect, positive affect, and autonomic arousalQ74596124
P433issue3
P304page(s)527-532
P577publication date2012-02-23
P1433published inNature ProtocolsQ3337109
P1476titleAssessing fear and anxiety in humans using the threat of predictable and unpredictable aversive events (the NPU-threat test)
P478volume7

Reverse relations

cites work (P2860)
Q92536147A Proof-of-Mechanism Study to Test Effects of the NMDA Receptor Antagonist Lanicemine on Behavioral Sensitization in Individuals With Symptoms of PTSD
Q30446439A potentiated startle study of uncertainty and contextual anxiety in adolescents diagnosed with autism spectrum disorder
Q47421633A pragmatic comparison of noise burst and electric shock unconditioned stimuli for fear conditioning research with many trials.
Q30453132A psychophysiological investigation of threat and reward sensitivity in individuals with panic disorder and/or major depressive disorder
Q30453024Acute tryptophan depletion increases translational indices of anxiety but not fear: serotonergic modulation of the bed nucleus of the stria terminalis?
Q95269742Allopregnanolone in premenstrual dysphoric disorder (PMDD): Evidence for dysregulated sensitivity to GABA-A receptor modulating neuroactive steroids across the menstrual cycle
Q35146656Amygdala-prefrontal cortex functional connectivity during threat-induced anxiety and goal distraction.
Q30392279Anticipation of smoking sufficiently dampens stress reactivity in nicotine-deprived smokers
Q47675070Anticipatory anxiety disrupts neural valuation during risky choice.
Q47426991Anxiety and Depression Symptom Dimensions Demonstrate Unique Relationships with the Startle Reflex in Anticipation of Unpredictable Threat in 8 to 14 Year-Old Girls
Q92297660Anxiety makes time pass quicker while fear has no effect
Q36819581Anxiety promotes memory for mood-congruent faces but does not alter loss aversion
Q30382371Anxiety sensitivity and the anticipation of predictable and unpredictable threat: Evidence from the startle response and event-related potentials.
Q37061858Anxiety-potentiated amygdala-medial frontal coupling and attentional control
Q30410146Are individual differences in appetitive and defensive motivation related? A psychophysiological examination in two samples
Q30410182Asians demonstrate reduced sensitivity to unpredictable threat: a preliminary startle investigation using genetic ancestry in a multiethnic sample
Q47314293Assessment of social transmission of threats in humans using observational fear conditioning
Q47347647Association between neural reactivity and startle reactivity to uncertain threat in two independent samples
Q36971316Association between problematic alcohol use and reactivity to uncertain threat in two independent samples
Q30401908Aversive responding to safety signals in panic disorder: the moderating role of intolerance of uncertainty
Q30433643Biomarkers of threat and reward sensitivity demonstrate unique associations with risk for psychopathology
Q47280370Cognitive bias modification for facial interpretation: a randomized controlled trial of transfer to self-report and cognitive measures in a healthy sample.
Q30365028Cognitive flexibility mediates the relation between intolerance of uncertainty and safety signal responding in those with panic disorder.
Q30360562Commonalities and differences in the neural substrates of threat predictability in panic disorder and specific phobia.
Q41790060Comparing the validity of informant and self-reports of personality using laboratory indices of emotional responding as criterion variables
Q57493702Defence response mobilization in response to provocation or imagery of interoceptive sensations in adolescents with chronic pain: a study protocol
Q38907943Defensive activation to (un)predictable interoceptive threat: The NPU respiratory threat test (NPUr).
Q30381984Defensive eye-blink startle responses in a human experimental model of anxiety.
Q47352302Defensive motivation and attention in anticipation of different types of predictable and unpredictable threat: A startle and event-related potential investigation
Q93026589Differential effects of experimentally induced anxiety and fear on pain: the role of anxiety sensitivity
Q89833674Distinct responses to predictable and unpredictable threat in anxiety pathologies: effect of panic attack
Q47300916Effect of Threat on Right dlPFC Activity during Behavioral Pattern Separation.
Q61440042Event-related potentials to threat of predictable and unpredictable shock
Q88325738Exercise decreases defensive responses to unpredictable, but not predictable, threat
Q57175022Exercise modulates the interaction between cognition and anxiety in humans
Q47550555Extended amygdala connectivity changes during sustained shock anticipation.
Q30424359How bad could it be? Alcohol dampens stress responses to threat of uncertain intensity
Q47976744How many blinks are necessary for a reliable startle response? A test using the NPU-threat task
Q64071984I just lost it! Fear and anger reduce the sense of agency: a study using intentional binding
Q49563020If or when? Uncertainty's role in anxious anticipation.
Q47122888Impact of Panic on Psychophysiological and Neural Reactivity to Unpredictable Threat in Depression and Anxiety
Q34177760Improvement in suicidal ideation after ketamine infusion: relationship to reductions in depression and anxiety.
Q30410311Increased fear-potentiated startle in major depressive disorder patients with lifetime history of suicide attempt
Q102210905Locomotion in virtual environments predicts cardiovascular responsiveness to subsequent stressful challenges
Q89747627Low-frequency parietal repetitive transcranial magnetic stimulation reduces fear and anxiety
Q30450782Major depression is not associated with blunting of aversive responses; evidence for enhanced anxious anticipation
Q91609151Mechanistic link between right prefrontal cortical activity and anxious arousal revealed using transcranial magnetic stimulation in healthy subjects
Q41634123Modeling Avoidance in Mood and Anxiety Disorders Using Reinforcement Learning.
Q37597940Modeling Trait Anxiety: From Computational Processes to Personality.
Q92940436Modeling anxiety in healthy humans: a key intermediate bridge between basic and clinical sciences
Q35014617Multimodal assessment of long-term memory recall and reinstatement in a combined cue and context fear conditioning and extinction paradigm in humans
Q28080972Neural circuits in anxiety and stress disorders: a focused review
Q30413264Not just noise: individual differences in general startle reactivity predict startle response to uncertain and certain threat
Q38214082On the psychology of poverty
Q24603047Oxytocin increases anxiety to unpredictable threat
Q89639608Pediatric OCD in the era of RDoC
Q49922957Preliminary evidence that reactivity to uncertain threat is an endophenotype for alcohol use disorder.
Q39302789Probing for Neuroadaptations to Unpredictable Stressors in Addiction: Translational Methods and Emerging Evidence.
Q89454956Promoting long-term inhibition of human fear responses by non-invasive transcutaneous vagus nerve stimulation during extinction training
Q42175632Psychometric properties of startle and corrugator response in NPU, affective picture viewing, and resting state tasks.
Q47399574Reactivity to uncertain threat as a familial vulnerability factor for alcohol use disorder
Q46238981Reactivity to unpredictable threat as a treatment target for fear-based anxiety disorders
Q42363549Reducing State Anxiety Using Working Memory Maintenance
Q30453413Relation between Respiratory Sinus Arrythymia and Startle Response during Predictable and Unpredictable Threat
Q47374972Relationships among attention networks and physiological responding to threat
Q61810660Relief from incidental fear evokes exuberant risk taking
Q30431434Resting heart rate variability predicts safety learning and fear extinction in an interoceptive fear conditioning paradigm
Q92968151Resting-state connectivity of the bed nucleus of the stria terminalis and the central nucleus of the amygdala in clinical anxiety
Q54959846Roadmap for optimizing the clinical utility of emotional stress paradigms in human neuroimaging research.
Q48151810Role of the bed nucleus of the stria terminalis in aversive learning and memory.
Q34162930Selective and graded coding of reward uncertainty by neurons in the primate anterodorsal septal region
Q96591962Short-term nicotine deprivation alters dorsal anterior cingulate glutamate concentration and concomitant cingulate-cortical functional connectivity
Q47294593Social Fear Conditioning Paradigm in Virtual Reality: Social vs. Electrical Aversive Conditioning
Q39331037Social Fear Learning: from Animal Models to Human Function
Q35295530Social conditioning and extinction paradigm: a translational study in virtual reality.
Q47370507Startle potentiation to uncertain threat as a psychophysiological indicator of fear-based psychopathology: An examination across multiple internalizing disorders
Q30431764Startle response to unpredictable threat in comorbid panic disorder and alcohol dependence
Q88733638Startling Differences: Using the Acoustic Startle Response to Study Sex Differences and Neurosteroids in Affective Disorders
Q88283811Statistical power comparisons at 3T and 7T with a GO / NOGO task
Q89628504Stress Allostasis in Substance Use Disorders: Promise, Progress, and Emerging Priorities in Clinical Research
Q30449709Stress increases aversive prediction error signal in the ventral striatum.
Q97905608The 'Threat of Scream' paradigm: a tool for studying sustained physiological and subjective anxiety
Q30387331The CRH1 antagonist GSK561679 increases human fear but not anxiety as assessed by startle
Q48305886The Corticotropin Releasing Factor Receptor 1 in Alcohol Use Disorder: Still a Valid Drug Target?
Q47590513The Future of Contextual Fear Learning for PTSD Research: A Methodological Review of Neuroimaging Studies
Q28081635The Human BNST: Functional Role in Anxiety and Addiction
Q45065961The Unpredictive Brain Under Threat: A Neurocomputational Account of Anxious Hypervigilance.
Q47665953The effect of panic disorder versus anxiety sensitivity on event-related potentials during anticipation of threat
Q64990423The effect of trait anxiety on attentional mechanisms in combined context and cue conditioning and extinction learning.
Q30454171The impact of anxiety upon cognition: perspectives from human threat of shock studies
Q33861980The impact of induced anxiety on affective response inhibition.
Q90105572The impact of startle reactivity to unpredictable threat on the relation between bullying victimization and internalizing psychopathology
Q30418485The impact of stress on financial decision-making varies as a function of depression and anxiety symptoms
Q30401601The impact of threat of shock on the framing effect and temporal discounting: executive functions unperturbed by acute stress?
Q90723226The influence of threat on the efficiency of goal-directed attentional control
Q90714757The neural and computational systems of social learning
Q37388285The neural basis of improved cognitive performance by threat of shock.
Q64100148The neural circuitry of affect-induced distortions of trust
Q46058186The relationship between dlPFC activity during unpredictable threat and CO2-induced panic symptoms
Q90285681The research domain criteria framework in drug discovery for neuropsychiatric diseases: focus on negative valence
Q55051518Threat of shock and aversive inhibition: Induced anxiety modulates Pavlovian-instrumental interactions.
Q33817902Threat of shock increases excitability and connectivity of the intraparietal sulcus
Q30373209Time course of threat responding in panic disorder and depression.
Q35018402Too good to be true: rhesus monkeys react negatively to better-than-expected offers
Q28583117Towards an emotional 'stress test': a reliable, non-subjective cognitive measure of anxious responding
Q30378197Transcranial Direct Current Stimulation (tDCS) of the Right Inferior Frontal Gyrus Attenuates Skin Conductance Responses to Unpredictable Threat Conditions.
Q91226579Translating a rodent measure of negative bias into humans: the impact of induced anxiety and unmedicated mood and anxiety disorders
Q87681742Using Event-Related Potentials and Startle to Evaluate Time Course in Anxiety and Depression
Q38818550Using a cultural and RDoC framework to conceptualize anxiety in Asian Americans
Q30403053Using the threat probability task to assess anxiety and fear during uncertain and certain threat

Search more.