Synthesis and Biological Evaluation of Novel 2-Aminonicotinamide Derivatives as Antifungal Agents

scientific article

Synthesis and Biological Evaluation of Novel 2-Aminonicotinamide Derivatives as Antifungal Agents is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/CMDC.201600545
P698PubMed publication ID28071858

P2093author name stringJing Zhao
Ran Li
Xin Huang
Fei Xie
Yuanying Jiang
Dazhi Zhang
Chengxu Zang
Maomao An
Tingjunhong Ni
Zhan Cai
P2860cites workAnalysis of membrane topology and identification of essential residues for the yeast endoplasmic reticulum inositol acyltransferase Gwt1pQ27937181
Fundament and Prerequisites for the Application of an Antifungal TDM ServiceQ28085352
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E1210, a new broad-spectrum antifungal, suppresses Candida albicans hyphal growth through inhibition of glycosylphosphatidylinositol biosynthesisQ35689250
Abolishing Cell Wall Glycosylphosphatidylinositol-Anchored Proteins in Candida albicans Enhances Recognition by Host Dectin-1.Q35745515
Chemical Genomics-Based Antifungal Drug Discovery: Targeting Glycosylphosphatidylinositol (GPI) Precursor BiosynthesisQ36539252
Invasive fungal infections in congenital immunodeficienciesQ37788798
Emerging moulds: epidemiological trends and antifungal resistanceQ37889387
Antifungal drug resistance: mechanisms, epidemiology, and consequences for treatmentQ37971085
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Safety and interactions of new antifungals in stem cell transplant recipients.Q38036740
In vitro activity of E1210, a novel antifungal, against clinically important yeasts and moldsQ38627150
In vitro activity of a novel broad-spectrum antifungal, E1210, tested against Aspergillus spp. determined by CLSI and EUCAST broth microdilution methodsQ38725931
New insights into the functions of PIGF, a protein involved in the ethanolamine phosphate transfer steps of glycosylphosphatidylinositol biosynthesisQ38970512
Inhibiting GPI anchor biosynthesis in fungi stresses the endoplasmic reticulum and enhances immunogenicityQ39326660
New developments in invasive fungal diseaseQ39653795
First step of glycosylphosphatidylinositol (GPI) biosynthesis cross-talks with ergosterol biosynthesis and Ras signaling in Candida albicansQ41925698
In vitro activity of a novel broad-spectrum antifungal, E1210, tested against Candida spp. as determined by CLSI broth microdilution methodQ42731754
The Candida albicans homologue of PIG-P, CaGpi19p: gene dosage and role in growth and filamentationQ43006198
A prodrug approach towards the development of tricyclic-based FBPase inhibitorsQ43111809
Attributable mortality of nosocomial candidemia, revisitedQ44386169
Medicinal genetics approach towards identifying the molecular target of a novel inhibitor of fungal cell wall assemblyQ44444977
P433issue4
P304page(s)319-326
P577publication date2017-01-10
P1433published inChemMedChemQ2962252
P1476titleSynthesis and Biological Evaluation of Novel 2-Aminonicotinamide Derivatives as Antifungal Agents
P478volume12

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cites work (P2860)
Q9764448311g, a Potent Antifungal Candidate, Enhances Candida albicans Immunogenicity by Unmasking β-Glucan in Fungal Cell Wall
Q46248402Chemogenomic profiling of the fungal pathogen Candida albicans
Q39375330Drugs currently under investigation for the treatment of invasive candidiasis

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