Adenosine receptor expression in rheumatoid synovium: a basis for methotrexate action

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Adenosine receptor expression in rheumatoid synovium: a basis for methotrexate action is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1019922413
P356DOI10.1186/AR3871
P932PMC publication ID3446521
P698PubMed publication ID22682496
P5875ResearchGate publication ID225289891

P50authorRebecca RobertsQ113363133
Chris FramptonQ89444867
Lisa StampQ63042017
P2093author name stringJohn Highton
Paul A Hessian
Jody Hazlett
P2860cites workThe american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritisQ27860872
A simple salting out procedure for extracting DNA from human nucleated cellsQ27861086
The PI3K-NF-kappaB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritisQ28195442
Much Ado about Adenosine: Adenosine Synthesis and Function in Regulatory T Cell BiologyQ30433245
Clinical evidence for utilization of the A3 adenosine receptor as a target to treat rheumatoid arthritis: data from a phase II clinical trialQ33308049
Adenosine 5'-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation.Q34539873
Disease-modifying antirheumatic drugs are associated with a reduced risk for cardiovascular disease in patients with rheumatoid arthritis: a case control studyQ35605663
Methotrexate enhances the anti-inflammatory effect of CF101 via up-regulation of the A3 adenosine receptor expressionQ35630047
Polymorphisms within the adenosine receptor 2a gene are associated with adverse events in RA patients treated with MTX.Q36773117
TNF-alpha upregulates the A2B adenosine receptor gene: The role of NAD(P)H oxidase 4.Q36973962
Atheroprotective effects of methotrexate on reverse cholesterol transport proteins and foam cell transformation in human THP-1 monocyte/macrophagesQ37008144
A1 and A2 adenosine receptors in synovial cells from patients with rheumatic diseasesQ69422771
Synovial and serum levels of methotrexate during methotrexate therapy of rheumatoid arthritisQ69745928
Adenosine A1 receptor promotion of multinucleated giant cell formation by human monocytes: A mechanism for methotrexate-induced nodulosis in rheumatoid arthritisQ73491938
Relationship between genetic variants in the adenosine pathway and outcome of methotrexate treatment in patients with recent-onset rheumatoid arthritisQ80201783
The compaction of DNA helices into either continuous supercoils or folded-fiber rods and toroidsQ40128387
Inflammatory cytokines regulate function and expression of adenosine A(2A) receptors in human monocytic THP-1 cells.Q40779392
A new method for the isolation of deoxyribonucleic acids; evidence on the nature of bonds between deoxyribonucleic acid and proteinQ42954617
Polymorphisms within the folate pathway predict folate concentrations but are not associated with disease activity in rheumatoid arthritis patients on methotrexateQ43102130
Methotrexate polyglutamate concentrations are not associated with disease control in rheumatoid arthritis patients receiving long-term methotrexate therapyQ43180962
Normalization of A2A and A3 adenosine receptor up-regulation in rheumatoid arthritis patients by treatment with anti-tumor necrosis factor alpha but not methotrexateQ43269361
Adenosine A2A or A3 receptors are required for inhibition of inflammation by methotrexate and its analog MX-68.Q44278529
Methotrexate and mortality in patients with rheumatoid arthritis: a prospective studyQ44973310
The anti-inflammatory target A(3) adenosine receptor is over-expressed in rheumatoid arthritis, psoriasis and Crohn's disease.Q46019649
Inhibition of synoviocyte collagenase gene expression by adenosine receptor stimulationQ46199674
Cell-specific expression of TLR9 isoforms in inflammation.Q54399769
Overexpression of A3 adenosine receptor in peripheral blood mononuclear cells in rheumatoid arthritis: involvement of nuclear factor-kappaB in mediating receptor level.Q54562922
P433issue3
P921main subjectmethotrexateQ422232
P304page(s)R138
P577publication date2012-06-08
P1433published inArthritis Research and TherapyQ15757229
P1476titleAdenosine receptor expression in rheumatoid synovium: a basis for methotrexate action
P478volume14

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cites work (P2860)
Q39418010A3 Adenosine Receptors as Modulators of Inflammation: From Medicinal Chemistry to Therapy
Q40957424ATIC 347C>G gene polymorphism may be associated with methotrexate-induced adverse events in south Indian Tamil rheumatoid arthritis
Q34035228Adenosine signaling during acute and chronic disease states
Q95654925Analysis of association of ADORA2A and ADORA3 polymorphisms genotypes/haplotypes with efficacy and toxicity of methotrexate in patients with Rheumatoid arthritis
Q39043220Are gene polymorphisms related to treatment outcomes of methotrexate in patients with rheumatoid arthritis? A systematic review and meta-analysis
Q54525909Association of disease severity with IL-1 levels in methotrexate-treated psoriasis patients.
Q53093606Clinical-pharmacogenetic predictive models for MTX discontinuation due to adverse events in rheumatoid arthritis.
Q34885098Distinct effects of methotrexate and etanercept on the B cell compartment in patients with juvenile idiopathic arthritis
Q54974227Inhibition of IL-17 and IL-23 in Human Keratinocytes by the A3 Adenosine Receptor Agonist Piclidenoson.
Q38991972Mechanism of action of methotrexate in rheumatoid arthritis, and the search for biomarkers.
Q42975335Multi-omic landscape of rheumatoid arthritis: re-evaluation of drug adverse effects
Q38195630Pharmacogenetics and pharmacogenomics for rheumatoid arthritis responsiveness to methotrexate treatment: the 2013 update
Q42367885Purinergic Signalling: Therapeutic Developments
Q37468714Purinergic signalling in the musculoskeletal system.
Q89619982Signaling of the Purinergic System in the Joint
Q92990019The Adenosine A2B Receptor Drives Osteoclast-Mediated Bone Resorption in Hypoxic Microenvironments
Q55383408The Polymorphism in ADORA3 Decreases Transcriptional Activity and Influences the Chronic Heart Failure Risk in the Chinese.
Q58765606The human lymph node microenvironment unilaterally regulates T-cell activation and differentiation

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