A three-dimensional collagen lattice induces protein kinase C-zeta activity: role in alpha2 integrin and collagenase mRNA expression

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A three-dimensional collagen lattice induces protein kinase C-zeta activity: role in alpha2 integrin and collagenase mRNA expression is …
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scholarly articleQ13442814

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P356DOI10.1083/JCB.136.2.473
P8608Fatcat IDrelease_woyqmxxcbvat3ad4ezr2ra3amm
P932PMC publication ID2134818
P698PubMed publication ID9015316
P5875ResearchGate publication ID14194228

P2093author name stringJ Xu
R A Clark
P2860cites workThe primary structure of the VLA-2/collagen receptor alpha 2 subunit (platelet GPIa): homology to other integrins and the presence of a possible collagen-binding domainQ24307910
The cDNA sequence encoding human protein kinase C-zetaQ24318360
PKC zeta is a molecular switch in signal transduction of TNF-alpha, bifunctionally regulated by ceramide and arachidonic acidQ24568285
Lambda-interacting protein, a novel protein that specifically interacts with the zinc finger domain of the atypical protein kinase C isotype lambda/iota and stimulates its kinase activity in vitro and in vivoQ24650917
Collagen and collagenase gene expression in three-dimensional collagen lattices are differentially regulated by alpha 1 beta 1 and alpha 2 beta 1 integrinsQ24672275
Fibroblasts, myofibroblasts, and wound contractionQ24673630
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Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cellsQ27860599
Localization of protein kinase C isozymes in cardiac myocytesQ28259191
The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase CQ28289132
Protein kinase C and lipid signaling for sustained cellular responsesQ28300819
Downregulation of collagen synthesis in fibroblasts within three-dimensional collagen lattices involves transcriptional and posttranscriptional mechanisms.Q54391239
TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdownQ67505708
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Protein kinase C located in rat liver nuclei. Partial purification and biochemical and immunochemical characterizationQ69936614
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Differential translocation of protein kinase C epsilon during HeLa cell adhesion to a gelatin substratumQ71143132
betaII protein kinase C is required for the G2/M phase transition of cell cycleQ71143608
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Collagen matrices attenuate the collagen-synthetic response of cultured fibroblasts to TGF-betaQ71921693
A role for zeta protein kinase C in nerve growth factor-induced differentiation of PC12 cellsQ72089538
Platelet-activating factor induces airway mucin release via activation of protein kinase C: evidence for translocation of protein kinase C to membranesQ72102598
The cytoplasmic domain of alpha 6A integrin subunit is an in vitro substrate for protein kinase CQ72390057
Requirement for negative charge on "activation loop" of protein kinase CQ72808558
Self-stabilized antisense oligodeoxynucleotide phosphorothioates: properties and anti-HIV activityQ28378628
Activation of the FGF receptor underlies neurite outgrowth stimulated by L1, N-CAM, and N-cadherinQ28609642
Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogeneQ29618347
NF-kappa B: ten years afterQ29618566
Shuttling of pre-mRNA binding proteins between nucleus and cytoplasmQ29618907
Structure, regulation and function of NF-kappa BQ29620225
Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase CQ29620247
zeta PKC induces phosphorylation and inactivation of I kappa B-alpha in vitro.Q30448487
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Laminin mediates tissue-specific gene expression in mammary epitheliaQ34058782
Requirement for diacylglycerol and protein kinase C in HeLa cell-substratum adhesion and their feedback amplification of arachidonic acid production for optimum cell spreadingQ34436023
Beta 1 integrins signal lipid second messengers required during cell adhesionQ34452102
The c-rel protooncogene product represses NF-kappa B p65-mediated transcriptional activation of the long terminal repeat of type 1 human immunodeficiency virusQ36086609
Reorganization of polymerized actin: a possible trigger for induction of procollagenase in fibroblasts cultured in and on collagen gelsQ36215422
Decreased level of PDGF-stimulated receptor autophosphorylation by fibroblasts in mechanically relaxed collagen matricesQ36232788
Extracellular matrix alters PDGF regulation of fibroblast integrinsQ36236430
PDGF induction of alpha 2 integrin gene expression is mediated by protein kinase C-zetaQ36237368
A dominant negative protein kinase C zeta subspecies blocks NF-kappa B activationQ36694624
RelB, a new Rel family transcription activator that can interact with p50-NF-kappa B.Q36812702
Spreading of HeLa cells on a collagen substratum requires a second messenger formed by the lipoxygenase metabolism of arachidonic acid released by collagen receptor clusteringQ37372499
Evidence for the in vitro and in vivo interaction of Ras with protein kinase C zetaQ38301202
A sustained reduction in IkappaB-beta may contribute to persistent NF-kappaB activation in human endothelial cellsQ38355620
Modulation of transforming growth factor beta receptor levels on microvascular endothelial cells during in vitro angiogenesisQ39762254
The origin of the myofibroblasts in breast cancer. Recapitulation of tumor environment in culture unravels diversity and implicates converted fibroblasts and recruited smooth muscle cellsQ40342271
Multi-faceted regulation of cell differentiation by extracellular matrix.Q40824976
Role of MacMARCKS in integrin-dependent macrophage spreading and tyrosine phosphorylation of paxillinQ41197244
Platelet-derived growth factor-BB stimulates synthesis of the integrin alpha 2-subunit in human diploid fibroblastsQ41426771
Threonine-497 is a critical site for permissive activation of protein kinase C alphaQ41454413
Identification of the phosphorylated region responsible for the permissive activation of protein kinase C.Q41533899
Studies on the phosphorylation of protein kinase C-alpha.Q41628529
Integrin alpha 2 beta 1 is upregulated in fibroblasts and highly aggressive melanoma cells in three-dimensional collagen lattices and mediates the reorganization of collagen I fibrilsQ41653661
Localization of non-conventional protein kinase C isoforms in bovine brain cell nucleiQ42035905
Maintenance of NF-kappa B activity is dependent on protein synthesis and the continuous presence of external stimuliQ42182488
Structure and autoregulation of the c-rel promoter.Q42483155
Evidence for a bifurcation of the mitogenic signaling pathway activated by Ras and phosphatidylcholine-hydrolyzing phospholipase C.Q42824472
Phospholipase C-mediated hydrolysis of phosphatidylcholine is an important step in PDGF-stimulated DNA synthesisQ42832257
Protein kinase C zeta isoform is critical for kappa B-dependent promoter activation by sphingomyelinaseQ42835297
Phorbol ester regulation of opioid peptide gene expression in myocardial cells. Role of nuclear protein kinaseQ44340888
1,2-Diacylglycerols but not phorbol esters stimulate sphingomyelin hydrolysis in GH3 pituitary cellsQ44693718
Activation of protein kinase C precedes alpha 5 beta 1 integrin-mediated cell spreading on fibronectinQ46081423
Role of IkappaBalpha ubiquitination in signal-induced activation of NFkappaB in vivoQ47070611
The NF-kappa B p65 promoter.Q48130543
Activation of the zeta isozyme of protein kinase C by phosphatidylinositol 3,4,5-trisphosphate.Q48347794
Purification and characterization of the zeta isoform of protein kinase C from bovine kidneyQ48445022
zeta-Related protein kinase C in nuclei of nerve cellsQ49020082
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)473-483
P577publication date1997-01-01
P1433published inJournal of Cell BiologyQ1524550
P1476titleA three-dimensional collagen lattice induces protein kinase C-zeta activity: role in alpha2 integrin and collagenase mRNA expression
P478volume136

Reverse relations

cites work (P2860)
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