Mitogen activated protein kinase phosphatase-1 prevents the development of tactile sensitivity in a rodent model of neuropathic pain

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Mitogen activated protein kinase phosphatase-1 prevents the development of tactile sensitivity in a rodent model of neuropathic pain is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1030029821
P356DOI10.1186/1744-8069-8-34
P932PMC publication ID3460752
P698PubMed publication ID22540262
P5875ResearchGate publication ID224861277

P2093author name stringJoyce A DeLeo
Edgar Alfonso Romero-Sandoval
Christian Ndong
Russell P Landry
P2860cites workJNK-induced MCP-1 production in spinal cord astrocytes contributes to central sensitization and neuropathic painQ37194288
Evidence for the role of proteoglycans in cation-mediated gene transferQ37236667
Cannabinoid receptor type 2 activation induces a microglial anti-inflammatory phenotype and reduces migration via MKP induction and ERK dephosphorylationQ37246426
Distinct roles of matrix metalloproteases in the early- and late-phase development of neuropathic painQ39323926
Spinal injection of TNF-α-activated astrocytes produces persistent pain symptom mechanical allodynia by releasing monocyte chemoattractant protein-1Q42150441
Tumour necrosis factor-alpha induces ectopic activity in nociceptive primary afferent fibresQ44258496
p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain.Q44451943
Spinal blockade of TNF blocks spinal nerve ligation-induced increases in spinal P-p38.Q44751504
Systemic delivery of DNA or siRNA mediated by linear polyethylenimine (L-PEI) does not induce an inflammatory responseQ44986711
Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization.Q45072859
Spinal p38beta isoform mediates tissue injury-induced hyperalgesia and spinal sensitizationQ45301986
Repeated intrathecal administration of plasmid DNA complexed with polyethylene glycol-grafted polyethylenimine led to prolonged transgene expression in the spinal cordQ45863310
Efficient transfection method for primary cellsQ45886253
Brain-derived neurotrophic factor enhances the excitability of rat sensory neurons through activation of the p75 neurotrophin receptor and the sphingomyelin pathwayQ46616468
The endocannabinoid anandamide protects neurons during CNS inflammation by induction of MKP-1 in microglial cellsQ46875092
Polyethylenimine-mediated NGF gene delivery protects transected septal cholinergic neuronsQ47598961
RNA interference-mediated gene silencing of pleiotrophin through polyethylenimine-complexed small interfering RNAs in vivo exerts antitumoral effects in glioblastoma xenograftsQ48472950
Attenuation of the acute inflammatory response by dual specificity phosphatase 1 by inhibition of p38 MAP kinase.Q54359086
Clinical trial of the p38 MAP kinase inhibitor dilmapimod in neuropathic pain following nerve injury.Q54589616
Activation of p38 mitogen-activated protein kinase in spinal microglia contributes to incision-induced mechanical allodynia.Q54778599
Polyethylenimine-mediated DNA transfection of peripheral and central neurons in primary culture: probing Ca2+ channel structure and function with antisense oligonucleotidesQ71309191
Intrathecal interleukin-1 receptor antagonist in combination with soluble tumor necrosis factor receptor exhibits an anti-allodynic action in a rat model of neuropathic painQ73605805
Novel p38α mitogen-activated protein kinase inhibitor shows analgesic efficacy in acute postsurgical dental painQ84323026
Reduced MAP kinase phosphatase-1 degradation after p42/p44MAPK-dependent phosphorylationQ22011000
Evidence for a role of endocannabinoids, astrocytes and p38 phosphorylation in the resolution of postoperative painQ27325738
Distinct binding determinants for ERK2/p38alpha and JNK map kinases mediate catalytic activation and substrate selectivity of map kinase phosphatase-1Q28208304
Dexamethasone suppresses monocyte chemoattractant protein-1 production via mitogen activated protein kinase phosphatase-1 dependent inhibition of Jun N-terminal kinase and p38 mitogen-activated protein kinase in activated rat microgliaQ28571667
Quantitative assessment of tactile allodynia in the rat pawQ29617366
MAP kinase and painQ30482277
Low molecular weight polyethylenimines linked by beta-cyclodextrin for gene transfer into the nervous systemQ31034767
Size, diffusibility and transfection performance of linear PEI/DNA complexes in the mouse central nervous systemQ31984627
Cationic glycopolymers for the delivery of pDNA to human dermal fibroblasts and rat mesenchymal stem cellsQ33897526
Advances in neuropathic pain: diagnosis, mechanisms, and treatment recommendationsQ33973992
The evidence for pharmacological treatment of neuropathic painQ34130946
RNAi-mediated gene-targeting through systemic application of polyethylenimine (PEI)-complexed siRNA in vivoQ34379366
Spinal cannabinoid receptor type 2 activation reduces hypersensitivity and spinal cord glial activation after paw incisionQ34616582
Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses.Q34624894
p38 MAPK, microglial signaling, and neuropathic painQ36345136
Release of plasmid DNA-encoding IL-10 from PLGA microparticles facilitates long-term reversal of neuropathic pain following a single intrathecal administrationQ36642679
Efficacy of nonviral gene transfer in the canine brainQ36658314
Cytokine mechanisms of central sensitization: distinct and overlapping role of interleukin-1beta, interleukin-6, and tumor necrosis factor-alpha in regulating synaptic and neuronal activity in the superficial spinal cordQ36691900
A powerful nonviral vector for in vivo gene transfer into the adult mammalian brain: polyethylenimineQ36833845
Spinal microglial and perivascular cell cannabinoid receptor type 2 activation reduces behavioral hypersensitivity without tolerance after peripheral nerve injuryQ37108580
P921main subjectneuropathic painQ2798704
P304page(s)34
P577publication date2012-04-27
P1433published inMolecular PainQ15766244
P1476titleMitogen activated protein kinase phosphatase-1 prevents the development of tactile sensitivity in a rodent model of neuropathic pain
P478volume8

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cites work (P2860)
Q37721461A novel p38 MAPK docking-groove-targeted compound is a potent inhibitor of inflammatory hyperalgesia.
Q41815861A role for mitogen-activated protein kinase phosphatase 1 (MKP1) in neural cell development and survival.
Q38727831Current and Future Issues in the Development of Spinal Agents for the Management of Pain
Q64250777Dual-Specificity Phosphatase Regulation in Neurons and Glial Cells
Q33933720Epigenetic modification of DRG neuronal gene expression subsequent to nerve injury: etiological contribution to complex regional pain syndromes (Part II)
Q34404534Genomewide analysis of rat periaqueductal gray-dorsal horn reveals time-, region- and frequency-specific mRNA expression changes in response to electroacupuncture stimulation
Q37381399Glia and pain: is chronic pain a gliopathy?
Q35058471Lost but making progress--Where will new analgesic drugs come from?
Q38763122Macrophage-specific nanotechnology-driven CD163 overexpression in human macrophages results in an M2 phenotype under inflammatory conditions.
Q38222568Mitogen-Activated Protein Kinase Phosphatase (MKP)-1 in Nervous System Development and Disease
Q37735788Mitogen-activated protein kinase phosphatase-3 (MKP-3) in the surgical wound is necessary for the resolution of postoperative pain in mice.
Q33925526Neuropathic pain promotes adaptive changes in gene expression in brain networks involved in stress and depression
Q33925677Pathological pain and the neuroimmune interface
Q36223310Spinal cannabinoid receptor type 2 agonist reduces mechanical allodynia and induces mitogen-activated protein kinase phosphatases in a rat model of neuropathic pain
Q28300818Spinal mitogen-activated protein kinase phosphatase-3 (MKP-3) is necessary for the normal resolution of mechanical allodynia in a mouse model of acute postoperative pain
Q38019775The role of the immune system in the generation of neuropathic pain
Q24288817The search for novel analgesics: targets and mechanisms

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