The Molluscum Contagiosum Virus protein MC163 localizes to the mitochondria and dampens mitochondrial mediated apoptotic responses

scientific article

The Molluscum Contagiosum Virus protein MC163 localizes to the mitochondria and dampens mitochondrial mediated apoptotic responses is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.VIROL.2017.02.017
P698PubMed publication ID28235685

P2093author name stringDaniel Brian Nichols
Jesse Coutu
Joachim Bugert
Melissa R Ryerson
P2860cites workInteraction of F1L with the BH3 domain of Bak is responsible for inhibiting vaccinia-induced apoptosisQ24302248
Functional and structural studies of the vaccinia virus virulence factor N1 reveal a Bcl-2-like anti-apoptotic proteinQ24305049
Targeting the retinoblastoma protein by MC007L, gene product of the molluscum contagiosum virus: detection of a novel virus-cell interaction by a member of the poxviruses.Q39950893
Myxoma virus M11L blocks apoptosis through inhibition of conformational activation of Bax at the mitochondriaQ40329192
Myxoma virus M11L prevents apoptosis through constitutive interaction with Bak.Q40545931
Ultraviolet-induced cell death blocked by a selenoprotein from a human dermatotropic poxvirus.Q41070248
Expression of Toll-like receptors in verruca and molluscum contagiosumQ42420306
Molluscum contagiosum: immunomorphological aspects of keratinocytes markers of differentiation and adhesionQ42454306
An immunohistochemical study of abnormal keratinocyte proliferation in molluscum contagiosumQ42520388
The genome of molluscum contagiosum virus: analysis and comparison with other poxvirusesQ42659074
The protonophore CCCP induces mitochondrial permeability transition without cytochrome c release in human osteosarcoma cellsQ43713494
Leporipoxvirus Cu,Zn-superoxide dismutase (SOD) homologs are catalytically inert decoy proteins that bind copper chaperone for SOD.Q44457878
Effects of CCCP-induced mitochondrial uncoupling and cyclosporin A on cell volume, cell injury and preconditioning protection of isolated rabbit cardiomyocytesQ44485691
Bcl-2 prevents loss of mitochondria in CCCP-induced apoptosisQ45046130
Spontaneous regression of highly immunogenic Molluscum contagiosum virus (MCV)-induced skin lesions is associated with plasmacytoid dendritic cells and IFN-DC infiltrationQ45373465
Molluscum contagiosum virus inhibitors of apoptosis: The MC159 v-FLIP protein blocks Fas-induced activation of procaspases and degradation of the related MC160 proteinQ45738159
Stability of molluscum contagiosum virus DNA among 184 patient isolates: evidence for variability of sequences in the terminal inverted repeatsQ45854511
A novel family of viral death effector domain-containing molecules that inhibit both CD-95- and tumor necrosis factor receptor-1-induced apoptosisQ73201734
An immunohistochemical study of abnormal keratinocyte differentiation in molluscum contagiosumQ78032133
Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexesQ24312187
Vaccinia virus N1L protein resembles a B cell lymphoma-2 (Bcl-2) family proteinQ24319056
Vaccinia virus anti-apoptotic F1L is a novel Bcl-2-like domain-swapped dimer that binds a highly selective subset of BH3-containing death ligandsQ24321449
Structure-guided evolution of cyan fluorescent proteins towards a quantum yield of 93%.Q24606976
A structural viral mimic of prosurvival Bcl-2: a pivotal role for sequestering proapoptotic Bax and BakQ27644243
Fiji: an open-source platform for biological-image analysisQ27860912
FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).Q28240752
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complexQ28283294
Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymeraseQ28302692
Apoptosis: a review of programmed cell deathQ28305845
Modeling a snap-action, variable-delay switch controlling extrinsic cell deathQ28474253
The peripheral-type benzodiazepine receptor is involved in control of Ca2+-induced permeability transition pore opening in rat brain mitochondriaQ28572594
Mitochondrial membrane permeabilization in cell deathQ29547425
Vaccinia virus encodes a previously uncharacterized mitochondrial-associated inhibitor of apoptosisQ33717065
Tumorigenic poxviruses up-regulate intracellular superoxide to inhibit apoptosis and promote cell proliferationQ33755152
Quantitative analysis of pathways controlling extrinsic apoptosis in single cellsQ33807797
The vaccinia virus superoxide dismutase-like protein (A45R) is a virion component that is nonessential for virus replication.Q33844429
Programmed cell death and its role in inflammationQ34044165
The MC160 protein expressed by the dermatotropic poxvirus molluscum contagiosum virus prevents tumor necrosis factor alpha-induced NF-kappaB activation via inhibition of I kappa kinase complex formationQ34301763
Molluscum contagiosum virus infection.Q34366261
The global burden of skin disease in 2010: an analysis of the prevalence and impact of skin conditionsQ34380678
What is the mitochondrial permeability transition pore?Q34658211
Mitochondrial membrane potential probes and the proton gradient: a practical usage guideQ35047150
Defective CD95/APO-1/Fas signal complex formation in the human autoimmune lymphoproliferative syndrome, type Ia.Q35132088
Finding the right organelle. Targeting signals in mitochondrial outer-membrane proteinsQ35551096
Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosisQ35990527
The myxoma poxvirus protein, M11L, prevents apoptosis by direct interaction with the mitochondrial permeability transition pore.Q36371468
Apoptosome structure, assembly, and procaspase activation.Q38096568
Vaccinia virus immune evasion: mechanisms, virulence and immunogenicityQ38133695
Immune evasion strategies of molluscum contagiosum virus.Q38363426
Leporipoxvirus Cu-Zn superoxide dismutase homologs inhibit cellular superoxide dismutase, but are not essential for virus replication or virulenceQ38522699
Major apoptotic mechanisms and genes involved in apoptosisQ38802454
The vaccinia virus F1L protein interacts with the proapoptotic protein Bak and inhibits Bak activationQ39611834
P407language of work or nameEnglishQ1860
P921main subjectmitochondrionQ39572
molluscum contagiosumQ659584
apoptotic processQ14599311
P304page(s)91-101
P577publication date2017-02-21
P1433published inVirologyQ7934867
P1476titleThe Molluscum Contagiosum Virus protein MC163 localizes to the mitochondria and dampens mitochondrial mediated apoptotic responses
P478volume505

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cites work (P2860)
Q47546907A comparison of the effect of molluscum contagiosum virus MC159 and MC160 proteins on vaccinia virus virulence in intranasal and intradermal infection routes
Q38703178Molluscum Contagiosum Virus MC159 Abrogates cIAP1-NEMO Interactions and Inhibits NEMO Polyubiquitination.
Q64082642Molluscum contagiosum virus MC80 sabotages MHC-I antigen presentation by targeting tapasin for ER-associated degradation
Q40090965Poxviruses Utilize Multiple Strategies to Inhibit Apoptosis

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