Deciphering mode of action of heparanase using structurally defined oligosaccharides

scientific article

Deciphering mode of action of heparanase using structurally defined oligosaccharides is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M112.390161
P932PMC publication ID3464585
P698PubMed publication ID22893710
P5875ResearchGate publication ID230672073

P2093author name stringJian Liu
Sherket Peterson
P2860cites workRelease of cell surface‐associated basic fibroblast growth factor by glycosylphosphatidylinositol‐specific phospholipase CQ42820716
How APC/C orders destructionQ45345064
Structural recognition by recombinant human heparanase that plays critical roles in tumor metastasis. Hierarchical sulfate groups with different effects and the essential target disulfated trisaccharide sequenceQ24306149
Heparan sulfate D-glucosaminyl 3-O-sulfotransferase-3A sulfates N-unsubstituted glucosamine residuesQ28141121
Heparanase: structure, biological functions, and inhibition by heparin-derived mimetics of heparan sulfateQ28236334
Substrate specificity of heparanases from human hepatoma and plateletsQ28276774
Heparanase in glomerular diseasesQ28303555
Functions of cell surface heparan sulfate proteoglycansQ29618521
Chemoenzymatic Design of Heparan Sulfate Oligosaccharides*Q33668533
Unraveling the specificity of heparanase utilizing synthetic substratesQ33824982
Extended N-sulfated domains reside at the nonreducing end of heparan sulfate chains.Q33897755
Heparanases: endoglycosidases that degrade heparan sulfate proteoglycansQ34083497
Chemoenzymatic synthesis of homogeneous ultralow molecular weight heparinsQ34228210
Heparan sulfate: growth control with a restricted sequence menuQ34328757
Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasisQ34398151
Heparanase powers a chronic inflammatory circuit that promotes colitis-associated tumorigenesis in miceQ34876266
Heparan sulfate and heparanase play key roles in mouse β cell survival and autoimmune diabetesQ35640553
Interactions between heparan sulfate and proteins: the concept of specificityQ36552851
Heparanase: one molecule with multiple functions in cancer progressionQ37228578
Extracellular sequestration and release of fibroblast growth factor: a regulatory mechanism?Q37407186
Design of biologically active heparan sulfate and heparin using an enzyme-based approachQ37456178
Molecular model of human heparanase with proposed binding mode of a heparan sulfate oligosaccharide and catalytic amino acidsQ38333202
Mechanism of activation of human heparanase investigated by protein engineering.Q42045538
P433issue41
P407language of work or nameEnglishQ1860
P921main subjectoligosaccharideQ320607
P304page(s)34836-34843
P577publication date2012-08-14
P1433published inJournal of Biological ChemistryQ867727
P1476titleDeciphering mode of action of heparanase using structurally defined oligosaccharides
P478volume287

Reverse relations

cites work (P2860)
Q34634250A liquid chromatography-mass spectrometry-based approach to characterize the substrate specificity of mammalian heparanase
Q36771403Analysis of Total Human Urinary Glycosaminoglycan Disaccharides by Liquid Chromatography-Tandem Mass Spectrometry
Q90404382Characterization of Glycosaminoglycans in Gaping and Intact Connective Tissues of Farmed Atlantic Salmon (Salmo salar) Fillets by Mass Spectrometry
Q27005958Chemoenzymatic synthesis of heparan sulfate and heparin
Q38302345Discovery of a heparan sulfate 3-O-sulfation specific peeling reaction
Q47197453Evidence of glucuronidation of the glycation product LW-1: tentative structure and implications for the long-term complications of diabetes
Q37161285Glycan-based biomarkers for mucopolysaccharidoses
Q51742740Glycosaminoglycans affect heparanase location in CHO cell lines.
Q47897300Glycosidase Inhibition by Multivalent Presentation of Heparan Sulfate Saccharides on Bottlebrush Polymers.
Q38116039Heparan sulfate inhibitors and their therapeutic implications in inflammatory illnesses
Q37413886Heparanase and autoimmune diabetes.
Q91762127Heparanase as an Additional Tool for Detecting Structural Peculiarities of Heparin Oligosaccharides
Q36797594Heparanase induced by advanced glycation end products (AGEs) promotes macrophage migration involving RAGE and PI3K/AKT pathway
Q91087998Heparanase-1 activity and the early postnatal prostate development
Q92073912Heparanase: A Challenging Cancer Drug Target
Q42587945Heparanase: From basic research to therapeutic applications in cancer and inflammation
Q27025052Involvement of heparanase in atherosclerosis and other vessel wall pathologies
Q90680589Modulating Heparanase Activity: Tuning Sulfation Pattern and Glycosidic Linkage of Oligosaccharides
Q33676686Molecular mechanism of substrate specificity for heparan sulfate 2-O-sulfotransferase
Q35953176Role of Deacetylase Activity of N-Deacetylase/N-Sulfotransferase 1 in Forming N-Sulfated Domain in Heparan Sulfate
Q34501966Structural characterization of human heparanase reveals insights into substrate recognition.
Q59807297The Development of Assays for Heparanase Enzymatic Activity: Towards a Gold Standard
Q38238094The Role of Heparanase and Sulfatases in the Modification of Heparan Sulfate Proteoglycans within the Tumor Microenvironment and Opportunities for Novel Cancer Therapeutics
Q36744482Uncovering the Catalytic Direction of Chondroitin AC Exolyase: FROM THE REDUCING END TOWARDS THE NON-REDUCING END