dMyc is required in retinal progenitors to prevent JNK-mediated retinal glial activation

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dMyc is required in retinal progenitors to prevent JNK-mediated retinal glial activation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PGEN.1006647
P932PMC publication ID5360344
P698PubMed publication ID28267791

P50authorLígia TavaresQ54166515
Paulo S PereiraQ58391987
Joao RelvasQ43115278
P2093author name stringAndreia Correia
Marília A Santos
P2860cites workc-Myc regulates transcriptional pause releaseQ24629119
Glia-neuron interactions in the mammalian retinaQ26827435
Reduced expression of MYC increases longevity and enhances healthspanQ27323151
Tissue inhibitors of metalloproteinases: evolution, structure and functionQ28138083
Regulation of c-Myc through phosphorylation at Ser-62 and Ser-71 by c-Jun N-terminal kinaseQ28146223
Differential mitotic rates and patterns of growth in compartments in the Drosophila wingQ28280656
The mystery and magic of glia: a perspective on their roles in health and diseaseQ28300305
Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesisQ28574686
Induction of apoptosis by Drosophila Myc.Q47072146
Active JNK-dependent secretion of Drosophila Tyrosyl-tRNA synthetase by loser cells recruits haemocytes during cell competitionQ47072184
Traumatic scratch injury in astrocytes triggers calcium influx to activate the JNK/c-Jun/AP-1 pathway and switch on GFAP expressionQ48934397
c-Jun N-terminal kinases (JNKs) mediate pro-inflammatory actions of microgliaQ48987486
Drosophila's insulin/PI3-kinase pathway coordinates cellular metabolism with nutritional conditionsQ50319780
A transcriptional network controlling glial development in the Drosophila visual system.Q50585130
Loss of focal adhesions in glia disrupts both glial and photoreceptor axon migration in the Drosophila visual system.Q50646816
Myc-dependent regulation of ribosomal RNA synthesis during Drosophila development.Q50777362
Glia engulf degenerating axons during developmental axon pruning.Q52090523
Dpp and Hedgehog mediate neuron-glia interactions in Drosophila eye development by promoting the proliferation and motility of subretinal glia.Q52129050
Regulation of oligodendrocyte precursor migration by extracellular matrix: evidence for substrate-specific inhibition of migration by tenascin-C.Q52203491
Macrophages and glia participate in the removal of apoptotic neurons from the Drosophila embryonic nervous system.Q52536008
Drosophila myc regulates cellular growth during development.Q52573250
The Drosophila neuregulin vein maintains glial survival during axon guidance in the CNS.Q52592496
Gliatrophic and gliatropic roles of PVF/PVR signaling during axon guidance.Q52685423
Glial cell migration in the eye disc.Q52685780
The nucleolar protein Viriato/Nol12 is required for the growth and differentiation progression activities of the Dpp pathway during Drosophila eye development.Q52751325
Myc function in Drosophila.Q52760873
Profilin 1 is required for peripheral nervous system myelination.Q54373014
puckered, a gene involved in position-specific cell differentiation in the dorsal epidermis of the Drosophila larvaQ72104089
Activation of microglia during developmentally regulated cell death in the cerebral cortexQ73368368
Deregulation of glucose transporter 1 and glycolytic gene expression by c-MycQ73819236
The Janus role of c-Jun: cell death versus survival and regeneration of neonatal sympathetic and sensory neuronsQ81124477
Development of the peripheral glial cells in DrosophilaQ81657086
c-Jun N-terminal kinase induces axonal degeneration and limits motor recovery after spinal cord injury in miceQ84717365
Nutritional control of protein biosynthetic capacity by insulin via Myc in Drosophila.Q46821350
Temporal control of glial cell migration in the Drosophila eye requires gilgamesh, hedgehog, and eye specification genesQ46872089
Switch in FGF signalling initiates glial differentiation in the Drosophila eye.Q47070039
Spinster controls Dpp signaling during glial migration in the Drosophila eye.Q47070328
Homothorax switches function of Drosophila photoreceptors from color to polarized light sensors.Q47070368
Cells compete for decapentaplegic survival factor to prevent apoptosis in Drosophila wing development.Q47070908
Drosophila myc regulates organ size by inducing cell competitionQ47071644
Direct control of neurogenesis by selector factors in the fly eye: regulation of atonal by Ey and So.Q47071797
hemipterous encodes a novel Drosophila MAP kinase kinase, required for epithelial cell sheet movement.Q47071857
Developmental Axon Pruning Requires Destabilization of Cell Adhesion by JNK Signaling.Q47071981
Developmental regulation of glial cell phagocytic function during Drosophila embryogenesisQ47071982
dMyc transforms cells into super-competitorsQ47072112
Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addictionQ29616653
Astrocytes are active players in cerebral innate immunityQ29620562
Control of synapse number by gliaQ31832872
Nutritional control of gene expression in Drosophila larvae via TOR, Myc and a novel cis-regulatory elementQ33525405
Whole-genome analysis reveals a strong positional bias of conserved dMyc-dependent E-boxesQ33758260
Axonal control of oligodendrocyte developmentQ33796628
Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis.Q33948902
p38 mitogen-activated protein kinase can be involved in transforming growth factor beta superfamily signal transduction in Drosophila wing morphogenesisQ33957563
Astrocyte-neuron metabolic relationships: for better and for worseQ34025337
Drosophila insulin and target of rapamycin (TOR) pathways regulate GSK3 beta activity to control Myc stability and determine Myc expression in vivoQ34032753
Neuronal and glial cell biologyQ34085533
Axon injury and regeneration in the adult DrosophilaQ34091690
Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injuryQ34191628
A versatile ΦC31 based reporter system for measuring AP-1 and Nrf2 signaling in Drosophila and in tissue cultureQ34235097
The origin and development of glial cells in peripheral nervesQ34447586
c-MYC coordinately regulates ribosomal gene chromatin remodeling and Pol I availability during granulocyte differentiationQ34865252
DLK induces developmental neuronal degeneration via selective regulation of proapoptotic JNK activityQ35208477
Conserved metabolic energy production pathways govern Eiger/TNF-induced nonapoptotic cell deathQ35571337
Genetic analysis of fibroblast growth factor signaling in the Drosophila eyeQ35746922
Schwann cell autophagy, myelinophagy, initiates myelin clearance from injured nerves.Q35826034
MAP kinases and cell migrationQ35889220
Microglia: phagocyte and glia cell.Q35894049
A Myc-Groucho complex integrates EGF and Notch signaling to regulate neural development.Q36023696
Role of JNK activation in apoptosis: a double-edged swordQ36027363
Organ specification-growth control connection: new in-sights from the Drosophila eye-antennal discQ36036967
Glial control of synaptogenesisQ36039493
Phagocytosis in the developing CNS: more than clearing the corpsesQ36049250
wing blister, a new Drosophila laminin alpha chain required for cell adhesion and migration during embryonic and imaginal developmentQ36288392
Glial cell biology in Drosophila and vertebratesQ36352981
JNK regulation of oncogenesis.Q36472260
SCG10 is a JNK target in the axonal degeneration pathway.Q36504487
A subset of Drosophila Myc sites remain associated with mitotic chromosomes colocalized with insulator proteinsQ36613972
Extracellular Reactive Oxygen Species Drive Apoptosis-Induced Proliferation via Drosophila MacrophagesQ36614093
c-Jun is a negative regulator of myelination.Q36660683
MYC, metabolism, cell growth, and tumorigenesis.Q37040243
The role of microglia in central nervous system immunity and glioma immunologyQ37206898
Novel signals controlling embryonic Schwann cell development, myelination and dedifferentiationQ37207298
Microglial clearance function in health and diseaseQ37222916
Six-microns-under acts upstream of Draper in the glial phagocytosis of apoptotic neuronsQ37313845
Reflecting on 25 years with MYC.Q37333643
JNK protects Drosophila from oxidative stress by trancriptionally activating autophagyQ37361342
Drosophila laminins act as key regulators of basement membrane assembly and morphogenesis.Q37429771
Bendless modulates JNK-mediated cell death and migration in DrosophilaQ37578795
Modes and regulation of glial migration in vertebrates and invertebratesQ37601942
The eye imaginal disc as a model to study the coordination of neuronal and glial development.Q37693588
Nrg1/ErbB signaling networks in Schwann cell development and myelinationQ37787450
Regulation of synaptic connectivity by gliaQ37808619
Trophic neuron-glia interactions and cell number adjustments in the fruit fly.Q37898075
Glia unglued: how signals from the extracellular matrix regulate the development of myelinating gliaQ37915435
Intrinsic and extrinsic control of oligodendrocyte developmentQ38119763
Astrocyte glycogen as an emergency fuel under conditions of glucose deprivation or intense neural activityQ38231020
The Drosophila Nol12 homologue viriato is a dMyc target that regulates nucleolar architecture and is required for dMyc-stimulated cell growth.Q38338524
Genetic control of programmed cell death in DrosophilaQ38468332
The extracellular matrix niche microenvironment of neural and cancer stem cells in the brainQ38828938
C-MYC transcriptionally amplifies SOX2 target genes to regulate self-renewal in multipotent otic progenitor cellsQ38929791
ECM stiffness regulates glial migration in Drosophila and mammalian glioma modelsQ38971522
Regulation of Drosophila glial cell proliferation by Merlin-Hippo signalingQ38979328
JNK- and Fos-regulated Mmp1 expression cooperates with Ras to induce invasive tumors in DrosophilaQ39121816
Molecular Mechanisms Mediating Retinal Reactive Gliosis Following Bone Marrow Mesenchymal Stem Cell Transplantation.Q40198530
Polyploidization of glia in neural development links tissue growth to blood-brain barrier integrityQ40423624
puckered encodes a phosphatase that mediates a feedback loop regulating JNK activity during dorsal closure in DrosophilaQ40442820
c-Jun-NH2 kinase (JNK) contributes to the regulation of c-Myc protein stability.Q40615463
Corpse Engulfment Generates a Molecular Memory that Primes the Macrophage Inflammatory ResponseQ40664135
c-Jun reprograms Schwann cells of injured nerves to generate a repair cell essential for regenerationQ40803369
Suppression of Myc oncogenic activity by ribosomal protein haploinsufficiencyQ40890351
Drosophila PS2 and PS3 integrins play distinct roles in retinal photoreceptors-glia interactionsQ41322149
Parameters of cell competition in the compartments of the wing disc of DrosophilaQ41624173
The c-Jun kinase signaling cascade promotes glial engulfment activity through activation of draper and phagocytic functionQ41846027
JNK2 and JNK3 are major regulators of axonal injury-induced retinal ganglion cell deathQ42030670
Inhibition of c-Jun phosphorylation reduces axonal outgrowth of adult rat nodose ganglia and dorsal root ganglia sensory neuronsQ42170749
Migration and function of glia in the developing Drosophila eye.Q42474229
Migration of glia along photoreceptor axons in the developing Drosophila eye.Q42498111
JNK pathway activation is able to synchronize neuronal death and glial phagocytosis in DrosophilaQ43143428
Engulfing action of glial cells is required for programmed axon pruning during Drosophila metamorphosis.Q44844568
Developmentally programmed remodeling of the Drosophila olfactory circuitQ45230535
Social interactions among epithelial cells during tracheal branching morphogenesis.Q46029377
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue3
P304page(s)e1006647
P577publication date2017-03-07
P1433published inPLOS GeneticsQ1893441
P1476titledMyc is required in retinal progenitors to prevent JNK-mediated retinal glial activation
P478volume13

Reverse relations

cites work (P2860)
Q90384510CtBP represses Dpp-dependent Mad activation during Drosophila eye development
Q58693481HUWE1 Ubiquitin Ligase Regulates Endoreplication and Antagonizes JNK Signaling During Salivary Gland Development
Q90479112Radial Glia in Echinoderms
Q89881499The transcription factor Spalt and human homologue SALL4 induce cell invasion via the dMyc-JNK pathway in Drosophila

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