Highly expressed UNC119 promotes hepatocellular carcinoma cell proliferation through Wnt/β-catenin signaling and predicts a poor prognosis

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Highly expressed UNC119 promotes hepatocellular carcinoma cell proliferation through Wnt/β-catenin signaling and predicts a poor prognosis is …
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scholarly articleQ13442814

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P932PMC publication ID4656735
P698PubMed publication ID26693064

P2093author name stringWei Chai
Zhenyong Wang
Ruhai Liu
Bao Lei
P2860cites workHallmarks of Cancer: The Next GenerationQ22252312
UNC119 is required for G protein trafficking in sensory neuronsQ24305723
Unc119, a novel activator of Lck/Fyn, is essential for T cell activationQ24306892
Large-scale cDNA transfection screening for genes related to cancer development and progressionQ24561958
Gene amplification CCNE1 is related to poor survival and potential therapeutic target in ovarian cancerQ27851555
Wnt/beta-catenin signaling in development and diseaseQ27860784
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancerQ27860985
Cancer statistics, 2014Q27861018
Characterization of the gene for HRG4 (UNC119), a novel photoreceptor synaptic protein homologous to unc-119Q28116276
Proliferation, cell cycle and apoptosis in cancerQ28189476
Identification of UNC119 as a novel activator of SRC-type tyrosine kinasesQ28218689
Cancer cell cyclesQ29547756
Hepatocellular carcinomaQ29615841
Mammalian orthologs of C. elegans unc-119 highly expressed in photoreceptorsQ32006497
An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancerQ34345765
Unc119 regulates myofibroblast differentiation through the activation of Fyn and the p38 MAPK pathwayQ34639323
The promise and perils of Wnt signaling through beta-catenin.Q34647705
Redundant cyclin overexpression and gene amplification in breast cancer cellsQ36090819
Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targetsQ36104399
Wnt signaling and human diseases: what are the therapeutic implications?Q36702732
WNT signaling pathway and stem cell signaling networkQ36883377
Molecular targeted therapies in hepatocellular carcinomaQ37003665
Synthetic lethality between CCNE1 amplification and loss of BRCA1.Q37353157
Decreased expression of Neurensin-2 correlates with poor prognosis in hepatocellular carcinomaQ37386559
Mutations in the p53 tumor suppressor gene: clues to cancer etiology and molecular pathogenesisQ40694250
Mechanism ofcyclin D1 (CCND1, PRAD1) overexpression in human cancer cells: Analysis of allele-specific expressionQ41042080
Structure-activity relationship studies of small-molecule inhibitors of Wnt responseQ41963881
Cyclin D1 gene amplification in human laryngeal squamous cell carcinomas: prognostic significance and clinical implicationsQ43626941
Cyclin D1 overexpression correlates with poor prognosis in patients with tongue squamous cell carcinomaQ73616805
Molecular pathogenesis of human hepatocellular carcinomaQ74543031
WNT/β-catenin signaling and hepatocellular carcinomaQ87469831
P433issue10
P921main subjecthepatocellular carcinomaQ1148337
P304page(s)3123-3134
P577publication date2015-09-15
P1433published inAmerican Journal of Cancer ResearchQ17511667
P1476titleHighly expressed UNC119 promotes hepatocellular carcinoma cell proliferation through Wnt/β-catenin signaling and predicts a poor prognosis
P478volume5

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cites work (P2860)
Q64082681A Network-guided Association Mapping Approach from DNA Methylation to Disease
Q37373082Clinical significance and functional validation of PPA1 in various tumors
Q54246485Porcine Circovirus-Like Virus P1 Inhibits Wnt Signaling Pathway in Vivo and in Vitro
Q36288519Retracted: Exploration of inhibitory mechanisms of curcumin in lung cancer metastasis using a miRNA- transcription factor-target gene network
Q57929374UNC119 is a binding partner of tumor suppressor Ras-association domain family 6 and induces apoptosis and cell cycle arrest by MDM2 and p53

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