A structurally based approach to determine HLA compatibility at the humoral immune level

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A structurally based approach to determine HLA compatibility at the humoral immune level is …
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scholarly articleQ13442814

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P356DOI10.1016/J.HUMIMM.2006.08.001
P8608Fatcat IDrelease_zrp5idvcozalrprdt476gxsn5m
P932PMC publication ID2169290
P698PubMed publication ID17145365
P5875ResearchGate publication ID6654405

P2093author name stringRene J Duquesnoy
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Crystal structure of anti-Hen egg white lysozyme antibody (HyHEL-10) Fv-antigen complex. Local structural changes in the protein antigen and water-mediated interactions of Fv-antigen and light chain-heavy chain interfacesQ27619619
Three-dimensional structures of the free and antigen-bound Fab from monoclonal antilysozyme antibody HyHEL-63(,)Q27622663
Dissection of binding interactions in the complex between the anti-lysozyme antibody HyHEL-63 and its antigenQ27640276
Solution structure and activity of mouse lysozyme MQ27640600
High-resolution three-dimensional structure of horse heart cytochrome cQ27668194
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Crystal structure of a cross-reaction complex between Fab F9.13.7 and guinea fowl lysozymeQ27729792
Bound water molecules and conformational stabilization help mediate an antigen-antibody associationQ27731557
Hydrogen bonding and solvent structure in an antigen-antibody interface. Crystal structures and thermodynamic characterization of three Fv mutants complexed with lysozymeQ27734142
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A mutational analysis of binding interactions in an antigen-antibody protein-protein complexQ27758122
Structural basis for the binding of an anti-cytochrome c antibody to its antigen: crystal structures of FabE8-cytochrome c complex to 1.8 A resolution and FabE8 to 2.26 A resolutionQ27765034
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Conformations of immunoglobulin hypervariable regionsQ28273335
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Somatic generation of antibody diversityQ29616439
On the attribution of binding energy in antigen-antibody complexes McPC 603, D1.3, and HyHEL-5.Q30195996
Expressed murine and human CDR-H3 intervals of equal length exhibit distinct repertoires that differ in their amino acid composition and predicted range of structuresQ30746440
HLAMatchmaker-driven analysis of responses to HLA-typed platelet transfusions in alloimmunized thrombocytopenic patientsQ33369144
Binding in the growth hormone receptor complexQ33593803
Interactions of protein antigens with antibodiesQ33594252
Anatomy of the antibody moleculeQ34060425
Differences in electrostatic properties at antibody-antigen binding sites: implications for specificity and cross-reactivityQ34179284
Cloning and expression of the cDNA for the murine interferon gamma receptorQ34317120
Three-dimensional structure of an antibody-antigen complexQ34366479
Energetic and kinetic contributions of contact residues of antibody D1.3 in the interaction with lysozymeQ34413120
Reductionism and the search for structure-function relationships in antibody moleculesQ35007284
Antigen specificity and cross-reactivity of monoclonal anti-lysozyme antibodiesQ69000243
Site-directed chemical modification of horse cytochrome c results in changes in antigenicity due to local and long-range conformational perturbationsQ69002528
The expressed lysozyme-specific B cell repertoire. I. Heterogeneity in the monoclonal anti-hen egg white lysozyme specificity repertoire, and its difference from the in situ repertoireQ71000652
HLA-DR residues accessible under the peptide-binding groove contribute to polymorphic antibody epitopesQ71585528
Comparison of a structural and a functional epitopeQ71601556
Antigenic regions defined by monoclonal antibodies correspond to structural domains of avian lysozymeQ72733543
HLAmatchmaker: a molecularly based algorithm for histocompatibility determination. III. Effect of matching at the HLA-A,B amino acid triplet level on kidney transplant survivalQ73180837
Systematic exploration of the antigen binding activity of synthetic peptides isolated from the variable regions of immunoglobulinsQ73919852
Immunological speculationsQ79123866
The acceptable mismatch program as a fast tool for highly sensitized patients awaiting a cadaveric kidney transplantation: short waiting time and excellent graft outcomeQ80389325
Is the application of HLAMatchmaker relevant in kidney transplantation?Q81308319
HLAMatchmaker-based strategy to identify acceptable HLA class I mismatches for highly sensitized kidney transplant candidates.Q52009690
The number of amino acid residues mismatches correlates with flow cytometry crossmatching results in high PRA renal patients.Q52041496
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Alloreactive T cell recognition of MHC class I molecules: the T cell receptor interacts with limited regions of the MHC class I long alpha helices.Q52893012
A major histocompatibility complex-peptide-restricted antibody and t cell receptor molecules recognize their target by distinct binding modes: crystal structure of human leukocyte antigen (HLA)-A1-MAGE-A1 in complex with FAB-HYB3.Q52941721
Serum analysis after transplant nephrectomy reveals restricted antibody specificity patterns against structurally defined HLA class I mismatchesQ61053434
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Crystallographic refinement of the three-dimensional structure of the FabD1.3-lysozyme complex at 2.5-A resolutionQ67694554
Experimental analysis by site-directed mutagenesis of somatic mutation effects on affinity and fine specificity in antibodies specific for lysozymeQ67723990
Patterns of antibody specificity during the BALB/c immune response to hen eggwhite lysozymeQ67927284
Amino acid residues on HLA molecules critical for alloantibody bindingQ68188123
Small rearrangements in structures of Fv and Fab fragments of antibody D1.3 on antigen bindingQ68564328
Amino acid residues 56 to 69 of HLA-A2 specify an antigenic determinant shared by HLA-A2 and HLA-B17Q68963626
Three-dimensional structure of an antigen-antibody complex at 2.8 A resolutionQ68969863
Extending options for highly sensitized patients to receive a suitable kidney graftQ36220802
High-resolution mapping of the HyHEL-10 epitope of chicken lysozyme by site-directed mutagenesisQ36273475
Energetic analysis of an antigen/antibody interface: alanine scanning mutagenesis and double mutant cycles on the HyHEL-10/lysozyme interactionQ36281533
Purification of human gamma interferon receptors by sequential affinity chromatography on immobilized monoclonal antireceptor antibodies and human gamma interferonQ36353547
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The atomic mobility component of protein antigenicityQ38154881
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HLA-DR and -DQ epitopes and monoclonal antibody specificityQ38209752
How do two unrelated antibodies, HyHEL-10 and F9.13.7, recognize the same epitope of hen egg-white lysozyme?Q38270409
The contribution of contact and non-contact residues of antibody in the affinity of binding to antigen. The interaction of mutant D1.3 antibodies with lysozymeQ38313296
A proposal for the nomenclature of antigenic sites in peptides and proteinsQ39524030
The chemistry and mechanism of antibody binding to protein antigens.Q39539172
Structure of antibody-antigen complexes: implications for immune recognition.Q39539191
The structural basis of antibody complementarityQ39779292
The antigenic structure of proteins: a reappraisal.Q40076398
Impact of peptides on the recognition of HLA class I molecules by human HLA antibodiesQ40360031
Antibody-antigen interactions: new structures and new conformational changesQ40399620
Antibody structure and the evolution of immunoglobulin V gene segmentsQ40471075
Recent origin of the P lysozyme gene in miceQ40515705
The humoral immune response against an HLA class I allodeterminant correlates with the HLA-DR phenotype of the responderQ40802303
Probing HLA-B7 conformational shifts induced by peptide-binding groove mutations and bound peptide with anti-HLA monoclonal antibodies.Q41167755
Role of HLA-B*5101 binding nonamer peptides in formation of the HLA-Bw4 public epitopeQ41188726
Influence on antibody recognition of amino acid substitutions in the cleft of HLA-DQ2 molecules. Suggestive evidence of peptide-dependent epitopesQ41285221
Unusual distributions of amino acids in complementarity-determining (hypervariable) segments of heavy and light chains of immunoglobulins and their possible roles in specificity of antibody-combining sitesQ41295516
HLA-B16 antigens: sequence of the ST-16 antigen, further definition of two B38 subtypes and evidence for convergent evolution of B*3902.Q41396339
Bw4-reactive and Bw6-reactive antibodies recognize multiple distinct HLA structures that partially overlap in the alpha-1 helixQ41434617
Amino acids in the peptide-binding groove influence an antibody-defined, disease-associated HLA-DR epitopeQ41466223
HLA-DRβ chain residues that are predicted to be located in the floor of the peptide-binding groove contribute to antibody-binding epitopesQ41557902
Cn3D: a new generation of three-dimensional molecular structure viewerQ41576502
HLA-B∗0702 antibody epitopes are affected indirectly by distant antigen residuesQ41577346
Mutagenesis around residue 176 on HLA-B∗0702 characterizes multiple distinct epitopes for anti-HLA antibodiesQ41602436
Conformational changes in MHC class I molecules. Antibody, T-cell receptor, and NK cell recognition in an HLA-B7 model systemQ41649533
Biochemical implications from the variable gene sequences of an anti-cytochrome c antibody and crystallographic characterization of its antigen-binding fragment in free and antigen-complexed formsQ41665170
HLAMatchmaker-based analysis of human monoclonal antibody reactivity demonstrates the importance of an additional contact site for specific recognition of triplet-defined epitopesQ42665365
Monoclonal antibodies to horse cytochrome c expressing four distinct idiotypes distribute among two sites on the native protein.Q42800818
Quantitative estimation of HLA-A and HLA-B antigens carrying the Bw4 supertypic specificity in human peripheral blood lymphocytesQ44398319
Monoclonal antibodies as probes of conformational changes in protein-engineered cytochrome c.Q44839695
HLA epitope matching. Contribution of matched residues to epitopes recognized by alloantibodiesQ45162670
Magnitude of the hydrophobic effect at central versus peripheral sites in protein-protein interfacesQ45255575
Association of the anti-hen egg lysozyme antibody HyHEL-5 with avian species variant and mutant lysozymes.Q46017243
Predictive value of human leucocyte antigen epitope matching using HLAMatchmaker for graft outcomes in a predominantly African-American renal transplant cohortQ46984237
Identification of differences in the specificity-determining residues of antibodies that recognize antigens of different size: implications for the rational design of antibody repertoires.Q47425669
Antibody-antigen interactions: contact analysis and binding site topography.Q47628744
The number of amino acid triplet differences between patient and donor is predictive for the antibody reactivity against mismatched human leukocyte antigensQ47683551
Anatomy of an antibody molecule: structure, kinetics, thermodynamics and mutational studies of the antilysozyme antibody D1.3.Q47700146
Critical evaluation of the amino acid triplet-epitope matching concept in cadaver kidney transplantationQ47785748
Genetic and serological heterogeneity of the supertypic HLA-B locus specificities Bw4 and Bw6.Q48306828
Beneficial effect of matching at the HLA-A and -B amino-acid triplet level on rejection-free clear graft survival in penetrating keratoplasty.Q51034692
Utility of HLAMatchmaker and single-antigen HLA-antibody detection beads for identification of acceptable mismatches in highly sensitized patients awaiting kidney transplantation.Q51941761
HLA class I donor-specific triplet antibodies detected after renal transplantation.Q51990427
Humoral sensitization against rejected grafts: specific antibodies to graft immunogenic amino acid triplets.Q51990430
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)847-862
P577publication date2006-09-01
P1433published inHuman ImmunologyQ15709955
P1476titleA structurally based approach to determine HLA compatibility at the humoral immune level
P478volume67

Reverse relations

cites work (P2860)
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