Clinical and immunological relevance of antibodies in solid organ transplantation

scientific article published on December 2016

Clinical and immunological relevance of antibodies in solid organ transplantation is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1111/IJI.12294
P698PubMed publication ID27870356

P2093author name stringN K Mehra
A K Baranwal
P2860cites workNon-HLA antibodies targeting vascular receptors enhance alloimmune response and microvasculopathy after heart transplantation.Q52886517
Donor-specific HLA antibodies in a cohort comparing everolimus with cyclosporine after kidney transplantation.Q52889823
Four-year follow-up of a prospective trial of HLA and MICA antibodies on kidney graft survival.Q53243295
Epitopes of human leukocyte antigen class I antibodies found in sera of normal healthy males and cord blood.Q53503526
Impact of pretransplant human leukocyte antigen-C and -DP antibodies on kidney graft outcome.Q54338277
Endothelial gene expression in kidney transplants with alloantibody indicates antibody-mediated damage despite lack of C4d staining.Q54469292
The perlecan fragment LG3 is a novel regulator of obliterative remodeling associated with allograft vascular rejection.Q54550531
Can C4d Immunostaining on Endomyocardial Biopsies Be Considered a Prognostic Biomarker in Heart Transplant Recipients?Q58004270
Microdroplet Assay of Human Serum CytotoxinsQ59059757
No Association of Kidney Graft Loss With Human Leukocyte Antigen Antibodies Detected Exclusively by Sensitive Luminex Single-Antigen Testing: A Collaborative Transplant Study ReportQ59305666
Pre-Transplant Assessment of Donor-Reactive, HLA-Specific Antibodies in Renal Transplantation: Contraindication vs. RiskQ59314397
A second lineage of mammalian major histocompatibility complex class I genesQ24561936
Role of complement and NK cells in antibody mediated rejectionQ26864255
Donor-reactive HLA antibodies in renal allograft recipients: considerations, complications, and conundrums.Q30376242
Immunohistochemistry staining of C4d to diagnose antibody-mediated rejection in cardiac transplantationQ33326201
De novo production of K-alpha1 tubulin-specific antibodies: role in chronic lung allograft rejectionQ33551885
Preexisting donor-specific HLA antibodies predict outcome in kidney transplantationQ34124202
Association of HLA mismatch with death with a functioning graft after kidney transplantation: a collaborative transplant study reportQ34294557
Antiperlecan antibodies are novel accelerators of immune-mediated vascular injuryQ34595998
A lifetime versus a graft life approach redefines the importance of HLA matching in kidney transplant patientsQ34991120
De novo donor-specific HLA antibodies decrease patient and graft survival in liver transplant recipientsQ35535173
Anti-HLA antibody analysis and crossmatching in heart and lung transplantationQ35808818
Long term outcomes of transplantation using kidneys from expanded criteria donors: prospective, population based cohort study.Q35907637
The significance of donor-specific HLA antibodies in rejection and ductopenia development in ABO compatible liver transplantationQ35975914
Antibodies to K-α 1 tubulin and collagen V are associated with chronic rejection after lung transplantationQ36131035
Antibody-mediated rejection as a contributor to previously unexplained early liver allograft lossQ36216606
Extending options for highly sensitized patients to receive a suitable kidney graftQ36220802
A structurally based approach to determine HLA compatibility at the humoral immune levelQ36316220
Donor-specific antibodies adversely affect kidney allograft outcomes.Q36426146
Characteristics of Circulating Donor Human Leukocyte Antigen-specific Immunoglobulin G Antibodies Predictive of Acute Antibody-mediated Rejection and Kidney Allograft Failure.Q36509321
Antibody ligation of human leukocyte antigen class I molecules stimulates migration and proliferation of smooth muscle cells in a focal adhesion kinase-dependent mannerQ36584507
Effects of influenza immunization on humoral and cellular alloreactivity in humansQ36661931
A novel pathway of chronic allograft rejection mediated by NK cells and alloantibodyQ36887068
Antibody mediated rejection: update 2006.Q36910384
A role for antibodies to human leukocyte antigens, collagen-V, and K-α1-Tubulin in antibody-mediated rejection and cardiac allograft vasculopathyQ37044200
Why can sensitization by an HLA-DR2 mismatch lead to antibodies that react also with HLA-DR1?Q37300454
The emerging issue of MICA antibodies: antibodies to MICA and other antigens of endothelial cellsQ37323152
Proinflammatory events are associated with significant increases in breadth and strength of HLA-specific antibodyQ37575872
Endothelial transcripts uncover a previously unknown phenotype: C4d-negative antibody-mediated rejectionQ37654098
Renal transplantation across HLA and ABO antibody barriers: integrating paired donation into desensitization protocolsQ37685188
Barriers to successful transplantation of the sensitized patientQ37742103
Non-HLA-antibodies targeting Angiotensin type 1 receptor and antibody mediated rejectionQ38028216
Clinical relevance of antibody development in renal transplantationQ38079301
Current role of human leukocyte antigen matching in kidney transplantationQ38120397
Antibody-mediated graft injury: complement-dependent and complement-independent mechanisms.Q38169496
Donor-specific antibodies in allograft recipients: etiology, impact and therapeutic approachesQ38259069
HLA epitopes as viewed by antibodies: what is it all about?Q38364484
Incidence and impact of de novo donor-specific alloantibody in primary renal allograftsQ39472834
Pre-transplant serum concentrations of anti-endothelial cell antibody in panel reactive antibody negative renal recipients and its impact on acute rejectionQ39800052
Banff '09 meeting report: antibody mediated graft deterioration and implementation of Banff working groups.Q39904553
"Natural" human leukocyte antigen antibodies found in nonalloimmunized healthy malesQ39926228
Banff 07 classification of renal allograft pathology: updates and future directionsQ40121163
The relationship of anti-MICA antibodies and MICA expression with heart allograft rejection.Q40131011
Post-transplant soluble MICA and MICA antibodies predict subsequent heart graft outcomeQ40198908
The predictive value of soluble major histocompatibility complex class I chain-related molecule A (MICA) levels on heart allograft rejectionQ40244088
Serial ten-year follow-up of HLA and MICA antibody production prior to kidney graft failureQ40386334
Flow cytometry based detection of HLA alloantibody mediated classical complement activation.Q40597066
MICA, a new polymorphic HLA-related antigen, is expressed mainly by keratinocytes, endothelial cells, and monocytes.Q41069294
Major histocompatibility complex class 1 chain-related antigen a antibodies: sensitizing events and impact on renal graft outcomesQ42171607
A virtual crossmatch protocol significantly increases access of highly sensitized patients to deceased donor kidney transplantationQ42607322
A comparison of the survival of shipped and locally transplanted cadaveric renal allograftsQ42662484
Transplant glomerulopathy, late antibody-mediated rejection and the ABCD tetrad in kidney allograft biopsies for causeQ43580802
Pretransplant sensitization against angiotensin II type 1 receptor is a risk factor for acute rejection and graft lossQ43817587
Pre-transplant donor specific anti-HLA antibody is associated with antibody-mediated rejection, progressive graft dysfunction and patient deathQ43829027
Deleterious impact of HLA-DRB1 allele mismatch in sensitized recipients of kidney retransplantsQ43846537
Analysis of factors that affect outcome after transplantation of kidneys donated after cardiac death in the UK: a cohort study.Q43866270
HLA antibody specification using single-antigen beads--a technical solution for the prozone effectQ43914521
Presensitized kidney graft recipients with HLA class I and II antibodies are at increased risk for graft failure: a Collaborative Transplant Study reportQ43937861
Clinical relevance of pretransplant donor-specific HLA antibodies detected by single-antigen flow-beads.Q44092564
Antibodies to liver sinusoidal endothelial cells modulate immune responses in liver transplantationQ44323282
Clinical relevance of anti-HLA donor-specific antibodies detected by Luminex assay in the development of rejection after renal transplantationQ44418324
Shipping donor kidneys within Eurotransplant: outcomes after renal transplantation in a single-centre cohort study.Q44814399
Different impact of pretransplant anti-HLA antibodies detected by Luminex in highly sensitized renal transplanted patientsQ45122553
Naturally occurring interference in Luminex assays for HLA-specific antibodies: characteristics and resolutionQ45185527
Banff 2013 meeting report: inclusion of c4d-negative antibody-mediated rejection and antibody-associated arterial lesionsQ45342440
Consensus guidelines on the testing and clinical management issues associated with HLA and non-HLA antibodies in transplantationQ45627897
The impact of human leukocyte antigen mismatching on sensitization rates and subsequent retransplantation after first graft failure in pediatric renal transplant recipientsQ45768702
Each additional hour of cold ischemia time significantly increases the risk of graft failure and mortality following renal transplantation.Q45929361
Risk of fractures after renal transplantation in the United States.Q45960180
Early ultrastructural changes in renal allografts: correlation with antibody-mediated rejection and transplant glomerulopathy.Q45966400
Influence of CIT-induced DGF on kidney transplant outcomes.Q45991458
Harmful effect of preformed anti-MICA antibodies on renal allograft evolution in early posttransplantation periodQ46050956
Kidney transplantation in a recipient with anti-HLA antibody IgM positiveQ46056178
Deleterious impact of mismatching for human leukocyte antigen-C in presensitized recipients of kidney transplantsQ46086067
Impact of HLA mismatching on incidence of posttransplant non-hodgkin lymphoma after kidney transplantationQ46126470
Complement-binding anti-HLA antibodies and kidney-allograft survivalQ46141053
HLA high-resolution typing for sensitized patients: a solution in search of a problem?Q46153238
Association of mismatches for HLA-DR with incidence of posttransplant hip fracture in kidney transplant recipientsQ46189621
Impact of de novo donor-specific HLA antibodies detected by Luminex solid-phase assay after transplantation in a group of 88 consecutive living-donor renal transplantationsQ46897107
Sinusoidal C4d deposits in liver allografts indicate an antibody-mediated response: diagnostic considerations in the evaluation of liver allograftsQ46947691
Human leukocyte antigen antibodies and chronic rejection: from association to causationQ47563762
Significance of the positive crossmatch test in kidney transplantationQ47800073
Evolution and clinical pathologic correlations of de novo donor-specific HLA antibody post kidney transplant.Q48005087
Novel C1q assay reveals a clinically relevant subset of human leukocyte antigen antibodies independent of immunoglobulin G strength on single antigen beads.Q50618048
Antivimentin antibodies are an independent predictor of transplant-associated coronary artery disease after cardiac transplantation.Q50674616
Preformed class II donor-specific antibodies are associated with an increased risk of early rejection after liver transplantation.Q50895880
C4d fixing, luminex binding antibodies - a new tool for prediction of graft failure after heart transplantation.Q50899566
Desensitization in HLA-incompatible kidney recipients and survival.Q51018759
Luminex-based desensitization protocols: the University of Wisconsin initial experience.Q51038073
Living donor kidney transplantation in crossmatch-positive patients enabled by peritransplant immunoadsorption and anti-CD20 therapy.Q51413561
Detection of antibodies against HLA-C epitopes in patients with rejected kidney transplants.Q51621019
Eighteen-year follow-up of a retrospective study of HLA antibody on kidney graft survival.Q51794444
Predicting the immunogenicity of human leukocyte antigen class I alloantigens using structural epitope analysis determined by HLAMatchmaker.Q51874425
Utility of HLAMatchmaker and single-antigen HLA-antibody detection beads for identification of acceptable mismatches in highly sensitized patients awaiting kidney transplantation.Q51941761
A non-allogeneic stimulus triggers the production of de novo HLA antibodies in healthy adults.Q51969757
HLAMatchmaker: a molecularly based algorithm for histocompatibility determination. I. Description of the algorithm.Q52041500
Detection of anti-MICA antibodies in patients awaiting kidney transplantation, during the post-transplant course, and in eluates from rejected kidney allografts by Luminex flow cytometry.Q52668051
P433issue6
P921main subjectimmunologyQ101929
organ transplantationQ69253852
P304page(s)351-368
P577publication date2016-12-01
P1433published inInternational Journal of ImmunogeneticsQ15755115
P1476titleClinical and immunological relevance of antibodies in solid organ transplantation
P478volume43

Reverse relations

cites work (P2860)
Q55433988Does human leukocyte antigens sensitization matter for xenotransplantation?
Q39293464Herpesvirus microRNAs for use in gene therapy immune-evasion strategies
Q50193535Impact of human leukocyte antigen mismatch on lung transplant outcome
Q90537689Measuring alloreactive B cell responses in transplant recipients

Search more.