GDNF promotes tubulogenesis of GFRalpha1-expressing MDCK cells by Src-mediated phosphorylation of Met receptor tyrosine kinase

scientific article

GDNF promotes tubulogenesis of GFRalpha1-expressing MDCK cells by Src-mediated phosphorylation of Met receptor tyrosine kinase is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1083/JCB.200212174
P932PMC publication ID2172872
P698PubMed publication ID12682085
P5875ResearchGate publication ID10816500

P2093author name stringDavid Kaplan
Dmitry Poteryaev
Mart Saarma
Hannu Sariola
Alexandre Angers-Loustau
Anna Popsueva
Elena Arighi
Xiaojuan Meng
P2860cites workDefects in enteric innervation and kidney development in mice lacking GDNFQ24317594
GDNF-induced activation of the ret protein tyrosine kinase is mediated by GDNFR-alpha, a novel receptor for GDNFQ24329169
GFRα1 Is an Essential Receptor Component for GDNF in the Developing Nervous System and KidneyQ24649094
A simplified system for generating recombinant adenovirusesQ24682328
Lipid rafts and signal transductionQ28131735
Sustained recruitment of phospholipase C-gamma to Gab1 is required for HGF-induced branching tubulogenesisQ28139783
Expression of neurturin, GDNF, and GDNF family-receptor mRNA in the developing and mature mouseQ28140328
The GDNF family ligands and receptors - implications for neural developmentQ28144957
GDNF family neurotrophic factor signaling: four masters, one servant?Q28198154
Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinaseQ28286701
Scatter factor/hepatocyte growth factor is essential for liver developmentQ28504542
Renal agenesis and the absence of enteric neurons in mice lacking GDNFQ28594756
Lipid Domain Structure of the Plasma Membrane Revealed by Patching of Membrane ComponentsQ29620204
Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor RetQ29620364
GFRα-4, a New GDNF Family ReceptorQ32058878
GDNF and its receptors in the regulation of the ureteric branching.Q33759906
Src family tyrosine kinases and growth factor signalingQ33810017
Kidney morphogenesis: cellular and molecular regulationQ33855366
Released GFRalpha1 potentiates downstream signaling, neuronal survival, and differentiation via a novel mechanism of recruitment of c-Ret to lipid rafts.Q33933786
Activation of Trk neurotrophin receptors in the absence of neurotrophinsQ33937877
Characterization of protein tyrosine kinases from human breast cancer: involvement of the c-src oncogene product.Q34250172
GDNF recruits the signaling crew into lipid raftsQ34321609
Differential Response of Cortical Plate and Ventricular Zone Cells to GABA as a Migration StimulusQ34750391
Epithelial differentiation of metanephric mesenchymal cells after stimulation with hepatocyte growth factor or embryonic spinal cordQ35427474
Coexpression of hepatocyte growth factor and receptor (Met) in human breast carcinomaQ35773856
Roles of hepatocyte growth factor/scatter factor and the met receptor in the early development of the metanephrosQ36235129
The RET-glial cell-derived neurotrophic factor (GDNF) pathway stimulates migration and chemoattraction of epithelial cells.Q36290601
Glial cell line-derived neurotrophic factor activates the receptor tyrosine kinase RET and promotes kidney morphogenesisQ37289586
Co-operative effect of c-Src tyrosine kinase and Stat3 in activation of hepatocyte growth factor expression in mammary carcinoma cellsQ38302598
Human glial cell line-derived neurotrophic factor receptor alpha 4 is the receptor for persephin and is predominantly expressed in normal and malignant thyroid medullary cellsQ38305599
Expression of c-met is a strong independent prognostic factor in breast carcinomaQ38472256
NGF utilizes c-Ret via a novel GFL-independent, inter-RTK signaling mechanism to maintain the trophic status of mature sympathetic neurons.Q40755817
InIB-dependent internalization of Listeria is mediated by the Met receptor tyrosine kinaseQ40841869
Integrin-mediated RON growth factor receptor phosphorylation requires tyrosine kinase activity of both the receptor and c-SrcQ40889658
Cross-talk between epidermal growth factor receptor and c-Met signal pathways in transformed cellsQ40893206
Regulation of cell fate decision of undifferentiated spermatogonia by GDNF.Q40898231
GDNF triggers a novel ret-independent Src kinase family-coupled signaling via a GPI-linked GDNF receptor alpha1.Q40911466
Ret-dependent and -independent mechanisms of glial cell line-derived neurotrophic factor signaling in neuronal cellsQ40941497
Ret-mediated mitogenesis requires Src kinase activity.Q40968359
c-Src kinase activity is required for hepatocyte growth factor-induced motility and anchorage-independent growth of mammary carcinoma cellsQ40990822
GFRα-4 and the tyrosine kinase Ret form a functional receptor complex for persephinQ41008328
Glial-cell-line-derived neurotrophic factor is required for bud initiation from ureteric epitheliumQ41078366
Activated ras and ret oncogenes induce over-expression of c-met (hepatocyte growth factor receptor) in human thyroid epithelial cellsQ41109580
RET in human development and oncogenesisQ41113046
Hepatocyte growth factor (HGF) stimulates the tyrosine kinase activity of the receptor encoded by the proto-oncogene c-METQ41152225
RET mutations in human diseaseQ41196162
Localization of glial cell line-derived neurotrophic factor (GDNF) mRNA in embryonic rat by in situ hybridizationQ41207152
Embryonic expression of glial cell-line derived neurotrophic factor (GDNF) suggests multiple developmental roles in neural differentiation and epithelial-mesenchymal interactionsQ41249053
A protein tyrosine phosphatase activity associated with the hepatocyte growth factor/scatter factor receptorQ41533377
Identification of a fibroblast-derived epithelial morphogen as hepatocyte growth factorQ41656206
Scatter factor is a fibroblast-derived modulator of epithelial cell mobilityQ42807925
Identification of a hepatocyte growth factor autocrine loop in a murine mammary carcinomaQ42816811
Antiapoptotic and cytotoxic properties of delta opioid peptide [D‐Ala2,D‐Leu5]enkephalin in PC12 cellsQ43825644
Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomasQ45345804
GABA stimulates chemotaxis and chemokinesis of embryonic cortical neurons via calcium-dependent mechanismsQ49085438
Different point mutations in the met oncogene elicit distinct biological propertiesQ53413979
Renal agenesis and hypodysplasia in ret-k- mutant mice result from defects in ureteric bud developmentQ60418568
Expression of the c-ret proto-oncogene during mouse embryogenesisQ60418620
Differential requirement of Grb2 and PI3-kinase in HGF/SF-induced cell motility and tubulogenesisQ62771679
Modulation of HGF-induced tubulogenesis and branching by multiple phosphorylation mechanismsQ70495134
Epidermal growth factor receptor signaling activates met in human anaplastic thyroid carcinoma cellsQ74172362
Trisomy 7-harbouring non-random duplication of the mutant MET allele in hereditary papillary renal carcinomasQ77220529
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
P304page(s)119-129
P577publication date2003-04-07
P1433published inJournal of Cell BiologyQ1524550
P1476titleGDNF promotes tubulogenesis of GFRalpha1-expressing MDCK cells by Src-mediated phosphorylation of Met receptor tyrosine kinase
P478volume161

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Q39184517BMP4 reverses multidrug resistance through modulation of BCL-2 and GDNF in glioblastoma
Q37352330CD2AP and Cbl-3/Cbl-c constitute a critical checkpoint in the regulation of ret signal transduction
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Q28083626GDNF-Ret signaling in midbrain dopaminergic neurons and its implication for Parkinson disease
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Q40387355Glial cell line-derived neurotrophic factor-induced signaling in Schwann cells.
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