scholarly article | Q13442814 |
P356 | DOI | 10.1083/JCB.200109033 |
P8608 | Fatcat ID | release_6w2ibdgcljhynipu4x3xd3dd5i |
P932 | PMC publication ID | 2174048 |
P698 | PubMed publication ID | 12045181 |
P5875 | ResearchGate publication ID | 11328467 |
P50 | author | Christian Schöfer | Q55487403 |
P2093 | author name string | Martin Offterdinger | |
Thomas W Grunt | |||
Klara Weipoltshammer | |||
P2860 | cites work | Nucleocytoplasmic shuttling of endocytic proteins | Q24291367 |
Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors | Q24339400 | ||
Using neural networks for prediction of the subcellular location of proteins | Q24547827 | ||
Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue in the central conserved region | Q24685870 | ||
Expression of the c-erbB-3 protein in normal human adult and fetal tissues | Q28187551 | ||
gamma -Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase | Q28202328 | ||
Cooperative signaling of ErbB3 and ErbB2 in neoplastic transformation and human mammary carcinomas | Q28287906 | ||
Diversification of Neu differentiation factor and epidermal growth factor signaling by combinatorial receptor interactions | Q28609149 | ||
CRM1 is responsible for intracellular transport mediated by the nuclear export signal | Q29547861 | ||
Import(ance) of growth factors in(to) the nucleus | Q33606819 | ||
IL-1 and its receptor are translocated to the nucleus | Q33837186 | ||
The C-terminus of the kinase-defective neuregulin receptor ErbB-3 confers mitogenic superiority and dictates endocytic routing | Q33891080 | ||
Selective inhibition of the epidermal growth factor and HER2/neu receptors by tyrphostins | Q34334946 | ||
Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity | Q35684026 | ||
Expression of the ERBB3 gene product in breast cancer | Q35994633 | ||
A monoclonal antibody to the human c-erbB3 protein stimulates the anchorage-independent growth of breast cancer cell lines | Q36079584 | ||
Demonstration of ligand-dependent signaling by the erbB-3 tyrosine kinase and its constitutive activation in human breast tumor cells | Q36205683 | ||
Nuclear Translocation of fibroblast growth factor (FGF) receptors in response to FGF-2. | Q36236991 | ||
Growth factors in the nucleolus? | Q36255609 | ||
Importin beta-mediated nuclear import of fibroblast growth factor receptor: role in cell proliferation | Q36381086 | ||
Monoclonal antibody therapy of human cancer: Taking the HER2 protooncogene to the clinic | Q36517425 | ||
Regulation of phosphorylation of the c-erbB-2/HER2 gene product by a monoclonal antibody and serum growth factor(s) in human mammary carcinoma cells | Q36684680 | ||
Nuclear accumulation of fibroblast growth factor receptors is regulated by multiple signals in adrenal medullary cells | Q37382062 | ||
Efficient immortalization of luminal epithelial cells from human mammary gland by introduction of simian virus 40 large tumor antigen with a recombinant retrovirus | Q37490464 | ||
Nuclear localization of EGF receptor and its potential new role as a transcription factor | Q40782527 | ||
Betacellulin activates the epidermal growth factor receptor and erbB-4, and induces cellular response patterns distinct from those stimulated by epidermal growth factor or neuregulin-beta | Q41238288 | ||
Nuclear translocation and anchorage of the growth hormone receptor. | Q41409545 | ||
Nuclear localization of p185neu tyrosine kinase and its association with transcriptional transactivation | Q41441273 | ||
Biologic effects of heregulin/neu differentiation factor on normal and malignant human breast and ovarian epithelial cells. | Q41701569 | ||
Heregulin is rapidly translocated to the nucleus and its transport is correlated with c-myc induction in breast cancer cells. | Q46180928 | ||
Nerve growth factor receptors in chromatin of melanoma cells, proliferating melanocytes, and colorectal carcinoma cells in vitro | Q69046627 | ||
Use of a general purpose mammalian expression vector for studying intracellular protein targeting: identification of critical residues in the nuclear lamin A/C nuclear localization signal | Q70501370 | ||
The nucleolus | Q71214064 | ||
Nuclear expression of the c-erbB-4/HER-4 growth factor receptor in invasive breast cancers | Q73629078 | ||
Fibroblast growth factor 3, a protein with dual subcellular localization, is targeted to the nucleus and nucleolus by the concerted action of two nuclear localization signals and a nucleolar retention signal | Q73876953 | ||
Localizing the EGF receptor | Q77614138 | ||
P433 | issue | 6 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 929-939 | |
P577 | publication date | 2002-06-03 | |
P1433 | published in | Journal of Cell Biology | Q1524550 |
P1476 | title | c-erbB-3: a nuclear protein in mammary epithelial cells | |
P478 | volume | 157 |
Q35111697 | A multiscale modeling approach to investigate molecular mechanisms of pseudokinase activation and drug resistance in the HER3/ErbB3 receptor tyrosine kinase signaling network |
Q34907703 | A nuclear variant of ErbB3 receptor tyrosine kinase regulates ezrin distribution and Schwann cell myelination |
Q38551607 | Activated ErbB3 Translocates to the Nucleus via Clathrin-independent Endocytosis, Which Is Associated with Proliferating Cells |
Q78521210 | An ErbB2-Muc4 complex in rat ocular surface epithelia |
Q57291727 | An HER3-targeting antibody-drug conjugate incorporating a DNA topoisomerase I inhibitor U3-1402 conquers EGFR tyrosine kinase inhibitor-resistant NSCLC |
Q33290327 | An emerin "proteome": purification of distinct emerin-containing complexes from HeLa cells suggests molecular basis for diverse roles including gene regulation, mRNA splicing, signaling, mechanosensing, and nuclear architecture. |
Q34042332 | An unusual function of RON receptor tyrosine kinase as a transcriptional regulator in cooperation with EGFR in human cancer cells |
Q35058437 | Analysis of Somatic Mutations in Cancer: Molecular Mechanisms of Activation in the ErbB Family of Receptor Tyrosine Kinases |
Q37785155 | Beyond Lamins: Other Structural Components of the Nucleoskeleton |
Q36938534 | Biological function of nuclear receptor tyrosine kinase action |
Q34767641 | Biosynthesis of tumorigenic HER2 C-terminal fragments by alternative initiation of translation. |
Q36025400 | Bone microenvironment and androgen status modulate subcellular localization of ErbB3 in prostate cancer cells |
Q34868195 | Chaperone-mediated destruction of erbB2: relevance to tyrosine kinase inhibitors |
Q50698452 | Characterization of a novel tripartite nuclear localization sequence in the EGFR family. |
Q35456037 | Characterization of nuclear neurokinin 3 receptor expression in rat brain |
Q34077207 | Chromatin-associated CSF-1R binds to the promoter of proliferation-related genes in breast cancer cells |
Q80066141 | Clinical and prognostic significances of nuclear and cytoplasmic KIT expressions in extrahepatic bile duct carcinomas |
Q58112887 | Clinicopathological and prognostic correlations of HER3 expression and its degradation regulators, NEDD4-1 and NRDP1, in primary breast cancer |
Q33669979 | Cyclooxygenase-2 is a novel transcriptional target of the nuclear EGFR-STAT3 and EGFRvIII-STAT3 signaling axes |
Q34448627 | Direct Recruitment of Insulin Receptor and ERK Signaling Cascade to Insulin-Inducible Gene Loci |
Q33772914 | ERBB3: A potential serum biomarker for early detection and therapeutic target for devil facial tumour 1 (DFT1) |
Q28752378 | Embryonic requirements for ErbB signaling in neural crest development and adult pigment pattern formation |
Q24301949 | Emerin caps the pointed end of actin filaments: evidence for an actin cortical network at the nuclear inner membrane |
Q24297204 | Endosomal transport of ErbB-2: mechanism for nuclear entry of the cell surface receptor |
Q33691823 | Engineered Multivalency Enhances Affibody-Based HER3 Inhibition and Downregulation in Cancer Cells |
Q33538332 | Enhanced antiproliferative and apoptotic response to combined treatment of gamma-tocotrienol with erlotinib or gefitinib in mammary tumor cells |
Q39494243 | Epidermal growth factor receptors destined for the nucleus are internalized via a clathrin-dependent pathway |
Q37333995 | ErbB4 splice variants Cyt1 and Cyt2 differ by 16 amino acids and exert opposing effects on the mammary epithelium in vivo |
Q24633878 | Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3 |
Q35663809 | Evaluation of the prognostic significance of HER family mRNA expression in high-risk early breast cancer: a Hellenic Cooperative Oncology Group (HeCOG) validation study |
Q60046313 | Evaluation of the prognostic value of all four HER family receptors in patients with metastatic breast cancer treated with trastuzumab: A Hellenic Cooperative Oncology Group (HeCOG) study |
Q54642874 | Expression of HER-2 and nuclear localization of HER-3 protein in canine mammary tumors: histopathological and immunohistochemical study. |
Q34745805 | Expression of NRG1 and its receptors in human bladder cancer |
Q35558954 | Fulvestrant-induced expression of ErbB3 and ErbB4 receptors sensitizes oestrogen receptor-positive breast cancer cells to heregulin β1 |
Q40073439 | Generation of novel, secreted epidermal growth factor receptor (EGFR/ErbB1) isoforms via metalloprotease-dependent ectodomain shedding and exosome secretion. |
Q34506951 | HER-3 targeting alters the dimerization pattern of ErbB protein family members in breast carcinomas |
Q34048293 | HER4 D-box sequences regulate mitotic progression and degradation of the nuclear HER4 cleavage product s80HER4. |
Q33636880 | HMGN2 inducibly binds a novel transactivation domain in nuclear PRLr to coordinate Stat5a-mediated transcription. |
Q24650927 | Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway |
Q46620175 | Identification of novel nuclear localization signal within the ErbB-2 protein |
Q39840103 | Induction of ERBB2 nuclear transport after radiation in breast cancer cells |
Q36695203 | Inherent growth advantage of (pre)malignant hepatocytes associated with nuclear translocation of pro-transforming growth factor alpha. |
Q36020930 | Integrated and Functional Genomics Analysis Validates the Relevance of the Nuclear Variant ErbB380kDa in Prostate Cancer Progression. |
Q35831012 | Landscape of EGFR signaling network in human cancers: biology and therapeutic response in relation to receptor subcellular locations |
Q43601461 | Latent membrane protein 1-induced EGFR signalling is negatively regulated by TGF alpha prior to neoplasia. |
Q28250699 | Ligand-regulated association of ErbB-4 to the transcriptional co-activator YAP65 controls transcription at the nuclear level |
Q34577033 | Lmo7 is an emerin-binding protein that regulates the transcription of emerin and many other muscle-relevant genes |
Q39626907 | Localisation of Neuregulin 1-β3 to different sub-nuclear structures alters gene expression |
Q44733709 | Localization of neuregulin isoforms and erbB receptors in myelinating glial cells |
Q58325210 | Low nuclear ErbB3 predicts biochemical recurrence in patients with prostate cancer |
Q33830304 | MUC1 regulates nuclear localization and function of the epidermal growth factor receptor |
Q39570673 | Macropinocytosis inhibitors and Arf6 regulate ErbB3 nuclear localization in prostate cancer cells |
Q45012432 | Mapping nucleolar and spliceosome localization sequences of neuregulin1-beta3. |
Q55060477 | Meta-analysis reveals no significant correlation between breast cancer survival and ErbB3 expression. |
Q35014495 | Multiple protein domains contribute to nuclear import and cell toxicity of DUX4, a candidate pathogenic protein for facioscapulohumeral muscular dystrophy |
Q51794764 | Mutational analysis of ErbB2 intracellular localization. |
Q26773754 | Non-canonical signaling mode of the epidermal growth factor receptor family |
Q39812008 | Nuclear EGFR contributes to acquired resistance to cetuximab |
Q36376782 | Nuclear EGFR signalling network in cancers: linking EGFR pathway to cell cycle progression, nitric oxide pathway and patient survival. |
Q39560158 | Nuclear HER3 is associated with favorable overall survival in uveal melanoma |
Q40470698 | Nuclear accumulation of epidermal growth factor receptor and acceleration of G1/S stage by Epstein-Barr-encoded oncoprotein latent membrane protein 1. |
Q36798731 | Nuclear epidermal growth factor receptor (EGFR) interacts with signal transducer and activator of transcription 5 (STAT5) in activating Aurora-A gene expression |
Q36162605 | Nuclear functions and subcellular trafficking mechanisms of the epidermal growth factor receptor family |
Q24803707 | Nuclear localization and function of polypeptide ligands and their receptors: a new paradigm for hormone specificity within the mammary gland? |
Q35089368 | Nuclear localization and possible functions of receptor tyrosine kinases |
Q36798851 | Nuclear mode of the EGFR signaling network: biology, prognostic value, and therapeutic implications |
Q33998459 | Nuclear trafficking of the epidermal growth factor receptor family membrane proteins |
Q37622619 | Nuclear translocation of the epidermal growth factor receptor family membrane tyrosine kinase receptors |
Q35826198 | On the molecular basis of the receptor mosaic hypothesis of the engram |
Q35174240 | Perhexiline promotes HER3 ablation through receptor internalization and inhibits tumor growth |
Q36113481 | Proteolytic cleavage, trafficking, and functions of nuclear receptor tyrosine kinases |
Q37024025 | Radiation-induced EGFR-signaling and control of DNA-damage repair |
Q26830216 | Receptor tyrosine kinases in the nucleus |
Q34695460 | Regulation of hypermutation by activation-induced cytidine deaminase phosphorylation |
Q34949789 | Retracted: Mapping C-Terminal Transactivation Domains of the Nuclear HER Family Receptor Tyrosine Kinase HER3 |
Q42528205 | Role of the ErbB-4 carboxyl terminus in gamma-secretase cleavage |
Q24292840 | Role of the Sec61 translocon in EGF receptor trafficking to the nucleus and gene expression |
Q36351195 | STAT1 gene expression is enhanced by nuclear EGFR and HER2 via cooperation with STAT3 |
Q34810206 | Signalling shortcuts: cell-surface receptors in the nucleus? |
Q35177656 | Strategies to target HER2/neu overexpression for cancer therapy |
Q37190106 | Synergistic antitumor activity of histone deacetylase inhibitors and anti-ErbB3 antibody in NSCLC primary cultures via modulation of ErbB receptors expression. |
Q37417599 | Syntaxin 6-mediated Golgi translocation plays an important role in nuclear functions of EGFR through microtubule-dependent trafficking |
Q55071512 | Targeting ErbB-2 nuclear localization and function inhibits breast cancer growth and overcomes trastuzumab resistance. |
Q26864668 | Targeting of erbB3 receptor to overcome resistance in cancer treatment |
Q34246558 | Targeting the EGFR signaling pathway in cancer therapy |
Q37135372 | The ERBB3 receptor in cancer and cancer gene therapy |
Q24313108 | The ERBB4/HER4 receptor tyrosine kinase regulates gene expression by functioning as a STAT5A nuclear chaperone |
Q28564324 | The ErbB4 receptor in fetal rat lung fibroblasts and epithelial type II cells |
Q83150764 | The developing role of receptors and adaptors |
Q38971568 | The effect of resveratrol and its methylthio-derivatives on EGFR and Stat3 activation in human HaCaT and A431 cells |
Q34692233 | The epidermal growth factor receptor family: biology driving targeted therapeutics |
Q24296970 | The intracellular domain of ErbB4 induces differentiation of mammary epithelial cells |
Q35834849 | The nuclear epidermal growth factor receptor signaling network and its role in cancer |
Q24295651 | The phosphoinositide kinase PIKfyve mediates epidermal growth factor receptor trafficking to the nucleus |
Q53584304 | The profile of the epidermal growth factor system in rat endometrium during postpartum involution period. |
Q55033417 | The prolactin receptor transactivation domain is associated with steroid hormone receptor expression and malignant progression of breast cancer. |
Q37006174 | The role of ErbB3 and its binding partners in breast cancer progression and resistance to hormone and tyrosine kinase directed therapies |
Q39028181 | The role of HER2, EGFR, and other receptor tyrosine kinases in breast cancer |
Q34352437 | The translocon Sec61beta localized in the inner nuclear membrane transports membrane-embedded EGF receptor to the nucleus |
Q34267140 | Trafficking of epidermal growth factor receptor ligands in polarized epithelial cells |
Q37308472 | Trafficking of receptor tyrosine kinases to the nucleus |
Q28218537 | Transcriptional repressor germ cell-less (GCL) and barrier to autointegration factor (BAF) compete for binding to emerin in vitro |
Q36458755 | Transphosphorylation of kinase-dead HER3 and breast cancer progression: a new standpoint or an old concept revisited? |
Q24317732 | Tyrosine phosphorylation controls PCNA function through protein stability |
Q42474579 | Ultraviolet irradiation-induces epidermal growth factor receptor (EGFR) nuclear translocation in human keratinocytes |
Q38193173 | Uptake, internalization and nuclear translocation of radioimmunotherapeutic agents |
Search more.