Caspases disrupt the nuclear-cytoplasmic barrier

scientific article

Caspases disrupt the nuclear-cytoplasmic barrier is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1083/JCB.151.5.951
P932PMC publication ID2174353
P698PubMed publication ID11085998
P5875ResearchGate publication ID12241814

P2093author name stringY Lazebnik
L Faleiro
P2860cites workOrdering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent mannerQ22008727
Protease activation in apoptosis induced by MALQ22009976
Yeast Nucleoporins Involved in Passive Nuclear Envelope PermeabilityQ22066164
Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptorsQ24310559
Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosisQ24310597
DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosisQ24313625
The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosisQ24316760
Cleavage of lamin A by Mch2 alpha but not CPP32: multiple interleukin 1 beta-converting enzyme-related proteases with distinct substrate recognition properties are active in apoptosisQ24629239
Nuclear pore complex contains a family of glycoproteins that includes p62: glycosylation through a previously unidentified cellular pathwayQ24633754
Nucleocytoplasmic transport: the soluble phaseQ28131723
From nucleoporins to nuclear pore complexesQ28238651
A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICADQ28258328
Death receptors: signaling and modulationQ28280897
Essential contribution of caspase 3/CPP32 to apoptosis and its associated nuclear changesQ28506930
The CED-3/ICE-like protease Mch2 is activated during apoptosis and cleaves the death substrate lamin AQ28610837
Caspases: enemies withinQ29547315
Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosisQ29614983
The asymmetric distribution of the constituents of the Ran system is essential for transport into and out of the nucleusQ29616325
Cell death: the significance of apoptosisQ29617620
Transport of proteins and RNAs in and out of the nucleusQ29619554
MaRX: an approach to genetics in mammalian cells.Q30654509
Getting across the nuclear pore complexQ33688034
Protein translocation in apoptosisQ33730384
Biochemical pathways of caspase activation during apoptosisQ33804316
Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic executionQ33882237
Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosisQ34451533
The caspase-3 precursor has a cytosolic and mitochondrial distribution: implications for apoptotic signalingQ36255096
Oncogene-dependent apoptosis is mediated by caspase-9.Q36795978
In vivo nuclear transport kinetics in Saccharomyces cerevisiaeQ40875229
Noninvasive monitoring of apoptosis versus necrosis in a neuroblastoma cell line expressing a nuclear pore protein tagged with the green fluorescent protein.Q41060342
Immunohistochemical analysis of in vivo patterns of expression of CPP32 (Caspase-3), a cell death protease.Q42437005
Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liverQ42543171
Apoptosis induction by caspase-8 is amplified through the mitochondrial release of cytochrome c.Q46355494
High levels of expression and nuclear localization of interleukin-1 beta converting enzyme (ICE) and CPP32 in favorable human neuroblastomas.Q48616022
Caspases: their intracellular localization and translocation during apoptosis.Q55033242
Differential Localization of ICAD-L and ICAD-S in Cells Due to Removal of a C-Terminal NLS from ICAD-L by Alternative SplicingQ60449570
ICAD/DFF Regulator of Apoptotic Nuclease Is NuclearQ60449581
Essential role of active nuclear transport in apoptosisQ73251599
Characterization of CPP32-like protease activity following apoptotic challenge in SH-SY5Y neuroblastoma cellsQ73373813
Proteases to die forQ74630246
Caspase-dependent proteolysis of integral and peripheral proteins of nuclear membranes and nuclear pore complex proteins during apoptosisQ77726315
P433issue5
P407language of work or nameEnglishQ1860
P1104number of pages9
P304page(s)951-959
P577publication date2000-11-01
P1433published inJournal of Cell BiologyQ1524550
P1476titleCaspases disrupt the nuclear-cytoplasmic barrier
P478volume151

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cites work (P2860)
Q512462295-Flurouracil disrupts nuclear export and nuclear pore permeability in a calcium dependent manner.
Q24674106A caspase cleavage fragment of p115 induces fragmentation of the Golgi apparatus and apoptosis
Q24534958A-kinase-anchoring protein 95 functions as a potential carrier for the nuclear translocation of active caspase 3 through an enzyme-substrate-like association
Q40599127Accurate Assessment of Cell Death by Imaging Flow Cytometry
Q34409669Acinus integrates AKT1 and subapoptotic caspase activities to regulate basal autophagy
Q24293646Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective
Q55109210Activation of Pro-apoptotic Caspases in Non-apoptotic Cells During Odontogenesis and Related Osteogenesis.
Q43284474Alteration of the nuclear pore complex in Ca(2+)-mediated cell death.
Q61638079Alterations in the nucleocytoplasmic transport in apoptosis: Caspases lead the way
Q44528203Apoptosis induced by different doses of caffeine on Chinese hamster ovary cells
Q36837574Apoptosis leads to a degradation of vital components of active nuclear transport and a dissociation of the nuclear lamina
Q58778369Apoptosis regulation by subcellular relocation of caspases
Q37985804Apoptosis signaling in influenza virus propagation, innate host defense, and lung injury
Q44371838Apoptosis-related fragmentation, translocation, and properties of human prothymosin alpha.
Q53433190Apoptotic histone modification inhibits nuclear transport by regulating RCC1.
Q37492721Bidirectional increase in permeability of nuclear envelope upon poliovirus infection and accompanying alterations of nuclear pores.
Q37088223Bik Mediates Caspase-Dependent Cleavage of Viral Proteins to Promote Influenza A Virus Infection.
Q39764205Caspase 3 activation is essential for efficient influenza virus propagation
Q43596172Caspase activity is not sufficient to execute cell death
Q35049064Caspase inhibitors as anti-inflammatory and antiapoptotic agents.
Q24292388Caspase proteolysis of the cohesin component RAD21 promotes apoptosis
Q42008487Caspase protocols in mice
Q40753178Caspase-2 can trigger cytochrome C release and apoptosis from the nucleus.
Q28201157Caspase-2-induced apoptosis is dependent on caspase-9, but its processing during UV- or tumor necrosis factor-dependent cell death requires caspase-3
Q31155049Caspase-8 sumoylation is associated with nuclear localization.
Q39602737Caspase-9-dependent nuclear translocation of cytochrome c in hypoxic injury
Q24324145Caspase-mediated cleavage of C53/LZAP protein causes abnormal microtubule bundling and rupture of the nuclear envelope
Q39216629Caspases rule the intracellular trafficking cartel
Q34467322Caspases target only two architectural components within the core structure of the nuclear pore complex
Q39993992Cell proliferation, apoptosis and mitochondrial damage in rat B50 neuronal cells after cisplatin treatment
Q36189670Cellular stress induces Bax-regulated nuclear bubble budding and rupture followed by nuclear protein release
Q43172447Ceramide synthase 6 modulates TRAIL sensitivity and nuclear translocation of active caspase-3 in colon cancer cells.
Q35825942Changes in Levels of Seminal Nitric Oxide Synthase, Macrophage Migration Inhibitory Factor, Sperm DNA Integrity and Caspase-3 in Fertile Men after Scrotal Heat Stress
Q28579902Characterization of a novel isoform of caspase-9 that inhibits apoptosis
Q60955684Chenodeoxycholic Acid from Bile Inhibits Influenza A Virus Replication via Blocking Nuclear Export of Viral Ribonucleoprotein Complexes
Q73513168Constitutive nuclear localization and initial cytoplasmic apoptotic activation of endogenous caspase-3 evidenced by confocal microscopy
Q42020101Contrasting nuclear dynamics of the caspase-activated DNase (CAD) in dividing and apoptotic cells
Q40598348Correlation between nucleocytoplasmic transport and caspase-3-dependent dismantling of nuclear pores during apoptosis.
Q34645070Deficiency in glutamine but not glucose induces MYC-dependent apoptosis in human cells.
Q44360258Deterioration of plasma membrane is associated with activated caspases in human spermatozoa
Q37913363Disruption of virus-host cell interactions and cell signaling pathways as an anti-viral approach against influenza virus infections
Q36820385Dual roles of intermediate filaments in apoptosis
Q30489286Dynamic release of nuclear RanGTP triggers TPX2-dependent microtubule assembly during the apoptotic execution phase
Q35013020Effector caspases and leukemia
Q39021916From the nucleus to the plasma membrane: translocation of the nuclear proteins histone H3 and lamin B1 in apoptotic microglia
Q96432266From threat to cure: understanding of virus-induced cell death leads to highly immunogenic oncolytic influenza viruses
Q26852062Host gene targets for novel influenza therapies elucidated by high-throughput RNA interference screens
Q46013323Human caspase-7 activity and regulation by its N-terminal peptide.
Q48148526Identifying and monitoring neurons that undergo metamorphosis-regulated cell death (metamorphoptosis) by a neuron-specific caspase sensor (Casor) in Drosophila melanogaster
Q90466773Imaging of morphological and biochemical hallmarks of apoptosis with optimized optogenetic tools
Q47352207Importin alpha/beta-mediated nuclear protein import is regulated in a cell cycle-dependent manner
Q33280982In vitro assay for the quantitation of apoptosis-induced alterations of nuclear envelope permeability
Q47179629In vitro effect of various cryoprotectants on the semen quality of endangered Oravka chicken.
Q73547330In vitro measurement of nuclear permeability changes in apoptosis
Q43943336Infection of glioma cells with Sindbis virus induces selective activation and tyrosine phosphorylation of protein kinase C delta. Implications for Sindbis virus-induced apoptosis
Q37247082Influenza viruses and the NF-kappaB signaling pathway - towards a novel concept of antiviral therapy
Q47111369Inhibition of chemotherapy-induced apoptosis of testicular cells by squid ink polysaccharide
Q39824944Interactions between viral and prokaryotic pathogens in a mixed infection with cardiovirus and mycoplasma
Q40772664Lack of correlation between caspase activation and caspase activity assays in paclitaxel-treated MCF-7 breast cancer cells
Q21559413Lethal influenza virus infection in macaques is associated with early dysregulation of inflammatory related genes
Q35091412Many cuts to ruin: a comprehensive update of caspase substrates
Q43002647Mechanism of action of interleukin-2 (IL-2)-Bax, an apoptosis-inducing chimaeric protein targeted against cells expressing the IL-2 receptor
Q40667287Mitochondrially localized active caspase-9 and caspase-3 result mostly from translocation from the cytosol and partly from caspase-mediated activation in the organelle. Lack of evidence for Apaf-1-mediated procaspase-9 activation in the mitochondria
Q38352783Modified annexin V/propidium iodide apoptosis assay for accurate assessment of cell death
Q36537332Monitoring the disruption of nuclear envelopes in interphase cells with GFP-beta-galactosidase
Q40470057Morphometric quantification of apoptotic stages in cell culture.
Q44847043Multiple mechanisms promote the inhibition of classical nuclear import upon exposure to severe oxidative stress
Q41573715Mutations in the M-gene segment can substantially increase replication efficiency of NS1 deletion influenza A virus in MDCK cells
Q43779020NF-kappa B activation mediates doxorubicin-induced cell death in N-type neuroblastoma cells
Q47253452Naturally Available Extracts Inhibiting Cancer Progression: A Systematic Review.
Q46351608Neutrophil gelatinase-associated lipocalin (NGAL) may play a protective role against rats ischemia/reperfusion renal injury via inhibiting tubular epithelial cell apoptosis
Q37682750Non-apoptotic cell death in Caenorhabditis elegans
Q42083926Non-apoptotic functions of caspase-7 during osteogenesis
Q42813889Nuclear Apaf-1 and cytochrome c redistribution following stress-induced apoptosis
Q34334379Nuclear apoptotic changes: an overview
Q52598302Nuclear entry of active caspase-3 is facilitated by its p3-recognition-based specific cleavage activity.
Q42585387Nuclear pore complex during neuronal degeneration: cracking the last barrier!
Q40486900Nuclear translocation of caspase-3 is dependent on its proteolytic activation and recognition of a substrate-like protein(s).
Q28357295Nucleocapsid Interacts with NPM1 and Protects it from Proteolytic Cleavage, Enhancing Cell Survival, and is Involved in PEDV Growth
Q34434945Nucleocytoplasmic traffic disorder induced by cardioviruses.
Q36110567Nucleocytoplasmic transport in apoptosis
Q30870732Pathological and therapeutic significance of cellular invasion by Proteus mirabilis in an enterocystoplasty infection stone model
Q53154841Perinuclear localization of the HIV-1 regulatory protein Vpr is important for induction of G2-arrest.
Q26825450Picornaviruses and nuclear functions: targeting a cellular compartment distinct from the replication site of a positive-strand RNA virus
Q39821157Plasma membrane and nuclear envelope integrity during the blebbing stage of apoptosis: a time-lapse study
Q40732879Polypyrimidine tract-binding proteins are cleaved by caspase-3 during apoptosis
Q37644563Potential biological role of poly (ADP-ribose) polymerase (PARP) in male gametes.
Q77110237Prevention of apoptotic neuronal death by controlling procaspases? A point of view
Q28345704Proapoptotic stimuli induce nuclear accumulation of glycogen synthase kinase-3 beta
Q28505968Prolonged nuclear retention of activated extracellular signal-regulated protein kinase promotes cell death generated by oxidative toxicity or proteasome inhibition in a neuronal cell line
Q28354545Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes
Q39289353Regulation of nuclear envelope permeability in cell death and survival
Q28244908Ricin triggers apoptotic morphological changes through caspase-3 cleavage of BAT3
Q44295660Role of caspases, Bid, and p53 in the apoptotic response triggered by histone deacetylase inhibitors trichostatin-A (TSA) and suberoylanilide hydroxamic acid (SAHA).
Q36618923Saikosaponin A inhibits influenza A virus replication and lung immunopathology
Q35599506Scrotal heat stress causes sperm chromatin damage and cysteinyl aspartate-spicific proteinases 3 changes in fertile men.
Q43966285Single-cell fluorescence resonance energy transfer analysis demonstrates that caspase activation during apoptosis is a rapid process. Role of caspase-3.
Q42916419Spatio-temporal activation of caspase revealed by indicator that is insensitive to environmental effects
Q47165049Squid ink polysaccharide prevents autophagy and oxidative stress affected by cyclophosphamide in Leydig cells of mice: a pilot study
Q40762197Staurosporine treatment and serum starvation promote the cleavage of emerin in cultured mouse myoblasts: involvement of a caspase-dependent mechanism
Q40044584Synergy of two low-affinity NLSs determines the high avidity of influenza A virus nucleoprotein NP for human importin α isoforms
Q47807724Systematic Quantification of Population Cell Death Kinetics in Mammalian Cells.
Q58180699Targeting cell signalling pathways to fight the flu: towards a paradigm change in anti-influenza therapy
Q38047645Targeting the host or the virus: current and novel concepts for antiviral approaches against influenza virus infection
Q36157011Temporal and spatial activation of caspase-like enzymes induced by self-incompatibility in Papaver pollen.
Q64898068The Effect of Furanocoumarin Derivatives on Induction of Apoptosis and Multidrug Resistance in Human Leukemic Cells.
Q30425939The NF-κB inhibitor SC75741 efficiently blocks influenza virus propagation and confers a high barrier for development of viral resistance
Q43626708The adapter protein apoptotic protease-activating factor-1 (Apaf-1) is proteolytically processed during apoptosis
Q40253423The extracellular release of HMGB1 during apoptotic cell death
Q39698264The major apoptotic pathway activated and suppressed by poliovirus.
Q33781297The maximal size of protein to diffuse through the nuclear pore is larger than 60kDa
Q35764439The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type.
Q94464929The nuclear envelope: target and mediator of the apoptotic process
Q36562688The nuclear pore complex, nuclear transport, and apoptosis
Q37271683Transport of the influenza virus genome from nucleus to nucleus
Q36373142Truncation of the TAR DNA-binding protein 43 is not a prerequisite for cytoplasmic relocalization, and is suppressed by caspase inhibition and by introduction of the A90V sequence variant
Q34290014Tyrosine phosphorylation of protein kinase Cdelta is essential for its apoptotic effect in response to etoposide
Q40516850Upon drug-induced apoptosis in lymphoma cells X-linked inhibitor of apoptosis (XIAP) translocates from the cytosol to the nucleus
Q81224424Variability in apoptotic response to poliovirus infection
Q74122492XIAP, the guardian angel
Q46793193γ-Rays-generated ROS induce apoptosis via mitochondrial and cell cycle alteration in smooth muscle cells.

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