Pharmacoproteomics identifies combinatorial therapy targets for diffuse large B cell lymphoma

scientific article

Pharmacoproteomics identifies combinatorial therapy targets for diffuse large B cell lymphoma is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI80714
P932PMC publication ID4665772
P698PubMed publication ID26529251
P5875ResearchGate publication ID283470401

P50authorGabriela ChiosisQ29515233
Leandro CerchiettiQ39201064
Kojo Elenitoba-JohnsonQ62479915
P2093author name stringAri Melnick
John P Leonard
Tony Taldone
Wayne Tam
Rita Shaknovich
Shao Ning Yang
Betty Chang
Rebecca L Goldstein
John Gerecitano
P2860cites workSrc-family kinases in B-cell development and signalingQ24307580
Chronic active B-cell-receptor signalling in diffuse large B-cell lymphomaQ24613755
STRING 8--a global view on proteins and their functional interactions in 630 organismsQ24656073
A gene expression-based method to diagnose clinically distinct subgroups of diffuse large B cell lymphomaQ24680233
Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarrayQ28204313
Affinity-based proteomics reveal cancer-specific networks coordinated by Hsp90Q28249103
Translocation of the B cell antigen receptor into lipid rafts reveals a novel step in signalingQ28513972
A guided tour into subcellular colocalization analysis in light microscopyQ29547199
Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitorsQ29547463
Geldanamycin-induced Lyn dissociation from aberrant Hsp90-stabilized cytosolic complex is an early event in apoptotic mechanisms in B-chronic lymphocytic leukemiaQ30157536
Regulation of the Src family kinase Lck by Hsp90 and ubiquitinationQ30164012
High-throughput combinatorial screening identifies drugs that cooperate with ibrutinib to kill activated B-cell-like diffuse large B-cell lymphoma cellsQ30433183
Displacement affinity chromatography of protein phosphatase one (PP1) complexesQ33383636
A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6-dependent B cell lymphomasQ33588432
The role of Hsp90N, a new member of the Hsp90 family, in signal transduction and neoplastic transformationQ34105950
SYK-dependent tonic B-cell receptor signaling is a rational treatment target in diffuse large B-cell lymphomaQ36445884
Cholesterol reporter moleculesQ36898794
Hsp90 inhibitor PU-H71, a multimodal inhibitor of malignancy, induces complete responses in triple-negative breast cancer modelsQ37208563
Targeting the Hsp90-associated viral oncoproteome in gammaherpesvirus-associated malignanciesQ37235682
Asymmetric Hsp90 N domain SUMOylation recruits Aha1 and ATP-competitive inhibitorsQ37661597
Hsp90 is essential for the synthesis and subsequent membrane association, but not the maintenance, of the Src-kinase p56(lck).Q38482173
PU-H71 effectively induces degradation of IκB kinase β in the presence of TNF-α.Q39082242
SYK inhibition modulates distinct PI3K/AKT- dependent survival pathways and cholesterol biosynthesis in diffuse large B cell lymphomasQ39140068
CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphomaQ43864036
Membrane cholesterol content accounts for developmental differences in surface B cell receptor compartmentalization and signalingQ46477086
P4510describes a project that usesImageJQ1659584
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)4559-4571
P577publication date2015-11-03
P1433published inJournal of Clinical InvestigationQ3186904
P1476titlePharmacoproteomics identifies combinatorial therapy targets for diffuse large B cell lymphoma
P478volume125

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