Macrophage peroxisome proliferator-activated receptor γ deficiency delays skin wound healing through impairing apoptotic cell clearance in mice

scientific article

Macrophage peroxisome proliferator-activated receptor γ deficiency delays skin wound healing through impairing apoptotic cell clearance in mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/CDDIS.2014.544
P932PMC publication ID4669743
P698PubMed publication ID25590807
P5875ResearchGate publication ID270964056

P50authorZhiren ZhangQ56027888
P2093author name stringM Jiang
Y Liu
X Yang
H Chen
Y Wu
J Xiong
L Qiu
R Shi
B Luo
P2860cites workImpaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant miceQ24669591
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Chemokine receptor CX3CR1 mediates skin wound healing by promoting macrophage and fibroblast accumulation and functionQ28505705
Macrophage-specific PPARgamma controls alternative activation and improves insulin resistanceQ29614354
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Cutaneous wound healingQ29618894
Human skin wounds: a major and snowballing threat to public health and the economyQ30227432
Peroxisome proliferator-activated receptors: from genes to physiologyQ32120242
Macrophage dysfunction impairs resolution of inflammation in the wounds of diabetic miceQ33537990
The phenotype of murine wound macrophagesQ33571172
Autoimmune kidney disease and impaired engulfment of apoptotic cells in mice with macrophage peroxisome proliferator-activated receptor gamma or retinoid X receptor alpha deficiencyQ33683897
Age-related alterations in the inflammatory response to dermal injuryQ34102040
Wound-healing defect of CD18(-/-) mice due to a decrease in TGF-beta1 and myofibroblast differentiationQ34116215
Dermal wound healing is subject to redox controlQ34425336
Advances in wound care and healing technologyQ34434007
Inflammatory cells during wound repair: the good, the bad and the uglyQ34456471
Phagocytosis of opsonized apoptotic cells: roles for 'old-fashioned' receptors for antibody and complementQ34649313
Upregulation of ski in fibroblast is implicated in the peroxisome proliferator--activated receptor δ-mediated wound healing.Q51536341
Wound healing in the PU.1 null mouse--tissue repair is not dependent on inflammatory cells.Q52103301
Wound healing defect of Vav3-/- mice due to impaired {beta}2-integrin-dependent macrophage phagocytosis of apoptotic neutrophils.Q52767124
Synergistic effect of peroxisome proliferator activated receptor-gamma and liver X receptor-alpha in the regulation of inflammation in macrophages.Q53608183
Macrophage phagocytosis of wound neutrophils.Q54109057
PPARgamma-dependent regulation of human macrophages in phagocytosis of apoptotic cells.Q54439080
Differential roles of macrophages in diverse phases of skin repair.Q54440277
The Local Effects of Cachectin/Tumor Necrosis Factor on Wound HealingQ67696849
Tumor necrosis factor alpha inhibits wound healing in the ratQ67875627
Editorial: macrophage functional phenotypes: no alternatives in dermal wound healing?Q82390208
The characteristic expression of B7-associated proteins in Langerhans cell sarcomaQ83392180
Peroxisome proliferator-activated receptor (PPAR)-beta as a target for wound healing drugs: what is possible?Q35178526
Critical roles of the nuclear receptor PPARbeta (peroxisome-proliferator-activated receptor beta) in skin wound healingQ35641318
Decreased macrophage number and activation lead to reduced lymphatic vessel formation and contribute to impaired diabetic wound healing.Q35691580
Sequential induction of pro- and anti-inflammatory prostaglandins and peroxisome proliferators-activated receptor-gamma during normal wound healing: a time course studyQ35740906
Tumor necrosis factor-alpha (TNF-α) is a therapeutic target for impaired cutaneous wound healingQ35779604
Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinedionesQ35794061
Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophilsQ36141195
Proresolution therapy for the treatment of delayed healing of diabetic wounds.Q36560613
Inflammation and wound healing: the role of the macrophageQ36679987
Pathophysiology of acute wound healingQ36727365
Clearance of apoptotic cells by phagocytesQ36850155
Rosiglitazone abrogates bleomycin-induced scleroderma and blocks profibrotic responses through peroxisome proliferator-activated receptor-gammaQ37071874
Regulation of macrophage functions by PPAR-alpha, PPAR-gamma, and LXRs in mice and men.Q37103503
Impaired apoptotic cell clearance in CGD due to altered macrophage programming is reversed by phosphatidylserine-dependent production of IL-4Q37116947
Sumoylation of peroxisome proliferator-activated receptor gamma by apoptotic cells prevents lipopolysaccharide-induced NCoR removal from kappaB binding sites mediating transrepression of proinflammatory cytokinesQ37185721
The liaison between apoptotic cells and macrophages--the end programs the beginning.Q37427782
Monocyte/macrophage androgen receptor suppresses cutaneous wound healing in mice by enhancing local TNF-alpha expressionQ37452288
Selective and specific macrophage ablation is detrimental to wound healing in miceQ37462741
Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR.Q37470344
Apoptotic cell: linkage of inflammation and wound healing.Q37497691
Molecular microbiology: new dimensions for cutaneous biology and wound healingQ37559264
Skin wound healing modulation by macrophagesQ37787051
Macrophages in skin injury and repairQ37833809
Modulation of macrophage phenotype by soluble product(s) released from neutrophils.Q40460717
Induction of CD36 expression by oxidized LDL and IL-4 by a common signaling pathway dependent on protein kinase C and PPAR-gammaQ40883227
Impaired wound healing in mouse models of diabetes is mediated by TNF-alpha dysregulation and associated with enhanced activation of forkhead box O1 (FOXO1).Q41776430
TNF-alpha suppresses alpha-smooth muscle actin expression in human dermal fibroblasts: an implication for abnormal wound healingQ42513753
An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and miceQ42652064
Abnormal cell responses and role of TNF-α in impaired diabetic wound healingQ43240676
Arginine metabolism in woundsQ43968290
Ca2+ release from sarcoplasmic reticulum of skinned fast- and slow-twitch muscle fibersQ44052217
Subcutaneous sponge modelsQ44490571
Antiinflammatory Roles of Peroxisome Proliferator–activated Receptor γ in Human Alveolar MacrophagesQ44620791
Wound fluid inhibits wound fibroblast nitric oxide synthesisQ45136040
PPARgamma agonists inhibit TGF-beta induced pulmonary myofibroblast differentiation and collagen production: implications for therapy of lung fibrosisQ45285303
PPAR gamma agonists can be expected to potentiate the efficacy of metronomic chemotherapy through CD36 up-regulationQ47574930
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P921main subjectmacrophageQ184204
wound healingQ1509074
apoptotic processQ14599311
P304page(s)e1597
P577publication date2015-01-15
P1433published inCell Death and DiseaseQ2197222
P1476titleMacrophage peroxisome proliferator-activated receptor γ deficiency delays skin wound healing through impairing apoptotic cell clearance in mice
P478volume6

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cites work (P2860)
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