Identification of epidermal growth factor receptor and its inhibitory microRNA141 as novel targets of Krüppel-like factor 8 in breast cancer

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Identification of epidermal growth factor receptor and its inhibitory microRNA141 as novel targets of Krüppel-like factor 8 in breast cancer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.18632/ONCOTARGET.4077
P932PMC publication ID4673276
P698PubMed publication ID26025929
P5875ResearchGate publication ID277406130

P2093author name stringLin Yu
Chao Shen
Jihe Zhao
Debarati Mukherjee
Heng Lu
Tianshu Li
Satadru K Lahiri
P2860cites workHuman Krüppel-like factor 8: a CACCC-box binding protein that associates with CtBP and represses transcriptionQ24516575
A reciprocal repression between ZEB1 and members of the miR-200 family promotes EMT and invasion in cancer cellsQ24649109
Most mammalian mRNAs are conserved targets of microRNAsQ24655061
MicroRNA regulation of cell lineages in mouse and human embryonic stem cellsQ24655106
Phosphotyrosine interactome of the ErbB-receptor kinase familyQ24672516
Cell signaling by receptor tyrosine kinasesQ27860474
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targetsQ27860792
The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1Q27861068
MicroRNAs: genomics, biogenesis, mechanism, and functionQ27861070
MicroRNA-directed cleavage of HOXB8 mRNAQ28131834
Identification of transcription factor KLF8 as a downstream target of focal adhesion kinase in its regulation of cyclin D1 and cell cycle progressionQ28181407
Krüppel-like factor 8 induces epithelial to mesenchymal transition and epithelial cell invasionQ28239064
KLF8 transcription factor participates in oncogenic transformationQ28251281
Altered MicroRNA expression confined to specific epithelial cell subpopulations in breast cancerQ28261558
microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastomaQ28280337
Epidermal growth factor-related peptides and their receptors in human malignanciesQ28293442
The primary structure of MEK, a protein kinase that phosphorylates the ERK gene productQ28316871
Epithelial-mesenchymal transition during oncogenic transformation induced by hexavalent chromium involves reactive oxygen species-dependent mechanism in lung epithelial cellsQ28686883
Regulation of mRNA translation and stability by microRNAsQ29547304
Coexpression of epidermal growth factor receptor with related factors is associated with a poor prognosis in non-small-cell lung cancerQ33206782
Use of immunohistochemical markers can refine prognosis in triple negative breast cancerQ33291587
EGFR signaling and drug discovery.Q34096763
Krüppel-like factor 8 (KLF8) is expressed in gliomas of different WHO grades and is essential for tumor cell proliferationQ34140599
Epidermal growth factor receptor tyrosine kinase inhibitor reverses mesenchymal to epithelial phenotype and inhibits metastasis in inflammatory breast cancerQ35007782
Status of epidermal growth factor receptor antagonists in the biology and treatment of cancerQ35177848
Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonizationQ35204515
Krüppel-like factor 8 emerges as an important regulator of cancerQ36185362
Regulation of the cell cycle by focal adhesion kinaseQ36328536
Epidermal growth factor receptor targeting in cancerQ36557269
Krüppel-like factor 8 promotes tumorigenic mammary stem cell induction by targeting miR-146aQ37096462
Role of epidermal growth factor receptor in breast cancerQ37320346
KLF8 and FAK cooperatively enrich the active MMP14 on the cell surface required for the metastatic progression of breast cancerQ37593817
KLF8 promotes human breast cancer cell invasion and metastasis by transcriptional activation of MMP9.Q37634359
Transformation of human ovarian surface epithelial cells by Krüppel-like factor 8.Q37685062
Identification of epithelial stromal interaction 1 as a novel effector downstream of Krüppel-like factor 8 in breast cancer invasion and metastasisQ37691895
Epidermal growth factor receptor in triple-negative and basal-like breast cancer: promising clinical target or only a marker?Q37694203
MicroRNAs in cancer: biomarkers, functions and therapyQ38229952
Activation of KLF8 transcription by focal adhesion kinase in human ovarian epithelial and cancer cellsQ38292525
Transcriptional activation of cyclin D1 promoter by FAK contributes to cell cycle progressionQ39250653
A novel role of Krüppel-like factor 8 in DNA repair in breast cancer cellsQ39252425
Lentivirus-mediated gene silencing of KLF8 reduced the proliferation and invasion of gastric cancer cellsQ39319079
KLF8 recruits the p300 and PCAF co-activators to its amino terminal activation domain to activate transcriptionQ39747094
Growth and motility inhibition of breast cancer cells by epidermal growth factor receptor degradation is correlated with inactivation of Cdc42.Q40296481
Pyk2 and FAK differentially regulate progression of the cell cycle.Q40863076
Downregulation of KLF8 expression by shRNA induces inhibition of cell proliferation in CAL27 human oral cancer cellsQ41865601
Regulation of the oncoprotein KLF8 by a switch between acetylation and sumoylationQ41873293
KLF8: so different in ovarian and breast cancerQ42062707
Prognostic markers in triple-negative breast cancerQ42505075
A unique sequence in the N-terminal regulatory region controls the nuclear localization of KLF8 by cooperating with the C-terminal zinc-fingersQ42798716
Sumoylation delimits KLF8 transcriptional activity associated with the cell cycle regulationQ42803296
Close similarity of epidermal growth factor receptor and v-erb-B oncogene protein sequences.Q53554133
Epidermal-growth-factor receptor status as predictor of early recurrence of and death from breast cancerQ69900051
Matrix metalloproteinase 9 and the epidermal growth factor signal pathway in operable non-small cell lung cancerQ73937563
Amplification and overexpression of the cyclin D1 and epidermal growth factor receptor genes in non-small-cell lung cancer. Lung Cancer Study GroupQ77220206
P433issue25
P407language of work or nameEnglishQ1860
P304page(s)21428-21442
P577publication date2015-05-27
P1433published inOncotargetQ1573155
P1476titleIdentification of epidermal growth factor receptor and its inhibitory microRNA141 as novel targets of Krüppel-like factor 8 in breast cancer
P478volume6

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cites work (P2860)
Q36730432Cancer stem cells and chemoresistance: The smartest survives the raid
Q58773628Cerium Oxide Nanoparticles Sensitize Pancreatic Cancer to Radiation Therapy through Oxidative Activation of the JNK Apoptotic Pathway
Q38780355Cytotoxic activity of physodic acid and acetone extract from Hypogymnia physodes against breast cancer cell lines
Q37693436Downregulation of miRNA-141 in breast cancer cells is associated with cell migration and invasion: involvement of ANP32E targeting.
Q36958359ERK2 phosphorylates Krüppel-like factor 8 protein at serine 48 to maintain its stability
Q41491494Genome-wide miRNA response to anacardic acid in breast cancer cells
Q42026653HOXC13 promotes proliferation of lung adenocarcinoma via modulation of CCND1 and CCNE1.
Q37269072Krüppel-like factor 8 activates the transcription of C-X-C cytokine receptor type 4 to promote breast cancer cell invasion, transendothelial migration and metastasis
Q41297598Krüppel-like factor 8 induces epithelial-to-mesenchymal transition and promotes invasion of pancreatic cancer cells through transcriptional activation of four and a half LIM-only protein 2
Q38754448Krüppel-like factor 8 promotes cancer stem cell-like traits in hepatocellular carcinoma through Wnt/β-catenin signaling
Q64085323Regulation of Krüppel-like factor 8 by the NEDD4 E3 ubiquitin ligase

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