Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores

scientific article

Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1200/JCO.2016.69.4935
P8608Fatcat IDrelease_2a2cmsyajrhhnlo5ratr6qxlmu
P932PMC publication ID5501359
P698PubMed publication ID28448241

P50authorOlufunmilayo OlopadeQ7088836
Shirley HodgsonQ15995134
Ali Amin Al OlamaQ57565560
Christi J van AsperenQ58235238
Anna Marie MulliganQ59659727
Esther M. JohnQ59752419
Douglas F. EastonQ59812154
Miguel de la HoyaQ60551322
Diana EcclesQ61756107
Kathleen ClaesQ62097128
Susan M DomchekQ62515230
Kenneth OffitQ20732365
Rita SchmutzlerQ21264574
Rosalind EelesQ24640445
Domenico PalliQ28360650
Ute HamannQ28484017
Gareth EvansQ29642643
Heli NevanlinnaQ29840669
Shan Wang-GohrkerQ30831711
Edith OlahQ62560279
Alfons MeindlQ63015490
Fergus J. CouchQ63018779
Susan L NeuhausenQ63019538
Jeffrey N WeitzelQ63032640
Lesley McGuffogQ63233438
Leigha SenterQ63370944
Barbara WappenschmidtQ63444312
Debra FrostQ64516041
Jacques SimardQ64516110
Irene L AndrulisQ64516140
Valentina SilvestriQ64821309
Conxi LázaroQ64856423
Marc TischkowitzQ66439010
Gord GlendonQ73633107
Nick OrrQ78318000
Julie LecarpentierQ80442806
Giulia CiniQ85938566
Marco MontagnaQ87215039
Torben A KruseQ87518225
Karin KastQ87624397
Jackie CookQ87691893
Lídia FeliubadalóQ45906974
Anne-Bine SkytteQ47502231
Ian G. CampbellQ47503141
Pedro PintoQ49097360
Uffe Birk JensenQ50544001
Mark RobsonQ51026477
Lone SundeQ51628358
Sara Gutiérrez-EnríquezQ54476812
Paolo RadiceQ37372139
Joan BrunetQ37378402
Stefania TommasiQ37843386
Manuel R. TeixeiraQ41584388
Alex HendersonQ41685184
Judith BalmañaQ41839999
Julian Weldon AdlardQ42687656
kConFab InvestigatorsQ42807245
Ana OsorioQ43181086
Norbert ArnoldQ43506746
Amanda SpurdleQ45904058
Karoline KuchenbaeckerQ37076233
Katherine L NathansonQ37369859
Alessandra VielQ55128539
Sylvie MazoyerQ55136930
Melissa C. SoutheyQ55446228
Ines ZannaQ56065913
Maria Adelaide CaligoQ56065914
Florentia FostiraQ56246077
Christoph EngelQ56261483
Mark H GreeneQ56435504
Adalgeir ArasonQ56436993
Jacopo AzzolliniQ56524223
Priyanka SharmaQ56524225
Daniel BarrowdaleQ56524229
Orland DiezQ56524234
Sofia KhanQ56551025
Bernard PeisselQ56551029
Siranoush ManoukianQ56697298
Yen Y TanQ56855815
Alex TeuléQ56855834
Goska LeslieQ56855923
Jesús Del ValleQ56855924
Javier BenitezQ56856067
Joe DennisQ56875626
Vijai JosephQ56875726
Rosa B BarkardottirQ114188703
Sue Kyung ParkQ114329424
Oskar T H JohannssonQ114337472
Yuan Chun DingQ114337484
Rachel C JankowitzQ114337490
Johanna I KiiskiQ114337491
Miquel Angel PujanaQ114337498
Elisa AlducciQ114337557
Laure BarjhouxQ114337610
Lucy E SideQ114337625
Nina DitschQ114337662
Rosemarie DavidsonQ114337667
Kim De LeeneerQ114337680
Sook-Yee YoonQ114337681
Silvia TognazzoQ114337691
Christine LassetQ114337700
Pragna GaddamQ114337735
Kai-Ren OngQ114337737
Muriel BelottiQ114337779
Anna Sara NavazioQ114452295
Virginia ValentiniQ114452300
Veronica ZelliQ114452301
Henriette Roed NielsenQ114579195
Veronica MediciQ117254050
Eric HahnenQ88011049
Zisun KimQ88109580
Dieter NiederacherQ88206719
Laura OttiniQ88368619
Doris SteinemannQ89074687
Soo Hwang TeoQ89171700
Laura CortesiQ89654300
Timothy R RebbeckQ89717690
Antonis C AntoniouQ89766295
Andrew K GodwinQ89896596
Trinidad CaldesQ90579504
Eunyoung KangQ90619959
Jonathan P TyrerQ91084019
Esther DarderQ91271701
Bernd DworniczakQ91271704
Pedro Pérez-SeguraQ91723131
David GoldgarQ91793745
Jihyoun LeeQ92628849
Kerstin RhiemQ92889178
Inge Søkilde PedersenQ93111381
Piera RizzoloQ95948200
Louise IzattQ95987963
Penny SoucyQ98148364
Carole BrewerQ98148371
Andrea GehrigQ98148373
GEMO Study CollaboratorsQ98148395
Francesca DamiolaQ98148424
Vanesa García-BarberánQ101050010
Anders Bryø BojesenQ105699099
Saundra S. BuysQ109562977
Tracy-Anne De SilvaQ112736228
Thomas V O HansenQ114122103
Mads ThomassenQ114122189
Bruce PoppeQ114166160
Bjarni A AgnarssonQ114188682
Anna von WachenfeldtQ114188695
P2093author name stringPaul James
Andreas Berger
Andrew Lee
Christian F Singer
Christian Sutter
Linda Steele
Lisa Walker
Steve Ellis
Mary E Porteous
Gillian Mitchell
Jennifer T Loud
Jan Hauke
Sung-Won Kim
Jong Won Lee
Min Hyuk Lee
Giuseppe Damante
Dezheng Huo
EMBRACE
HEBON
Lotte Krogh
Sarah M Nielsen
Angel Izquierdo
Angela Toss
Miklos Kasler
Jacob Musinsky
Helene Holland
Mattias Van Heetvelde
Christa Lorenchick
Dorothea Wand
Thomas A Conner
Tibor Vaszko
P2860cites workBRCA1 and BRCA2 mutations in a population-based study of male breast cancerQ24803673
Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer riskQ27008356
Multiple newly identified loci associated with prostate cancer susceptibilityQ28268180
Prostate cancer screening in men aged 50–69 years (STHLM3): a prospective population-based diagnostic studyQ29030107
Large-scale genotyping identifies 41 new loci associated with breast cancer riskQ29416989
Genome-wide association study identifies a common variant in RAD51B associated with male breast cancer riskQ29417050
Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association studyQ29417074
Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping arrayQ29417155
Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24.Q46332214
A risk prediction algorithm based on family history and common genetic variants: application to prostate cancer with potential clinical impactQ37632049
Male breast cancer: genetics, epigenetics, and ethical aspects.Q38153187
Novel and known genetic variants for male breast cancer risk at 8q24.21, 9p21.3, 11q13.3 and 14q24.1: results from a multicenter study in ItalyQ41507618
Cancer risks in BRCA2 families: estimates for sites other than breast and ovary.Q43073144
Association of low-penetrance alleles with male breast cancer risk and clinicopathological characteristics: results from a multicenter study in Italy.Q44567135
Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2.Q31043651
Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation CarriersQ33614244
Targeted prostate cancer screening in BRCA1 and BRCA2 mutation carriers: results from the initial screening round of the IMPACT studyQ33927384
Genetic variants at chromosomes 2q35, 5p12, 6q25.1, 10q26.13, and 16q12.1 influence the risk of breast cancer in menQ34031201
Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk predictionQ34394665
Cancer risks in BRCA2 mutation carriersQ34504452
Cancer Incidence in BRCA1 mutation carriersQ34527264
Breast cancer risk among male BRCA1 and BRCA2 mutation carriersQ34718829
Polygenic susceptibility to prostate and breast cancer: implications for personalised screeningQ34977428
Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulationQ35064451
Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer riskQ35102646
A meta-analysis of 87,040 individuals identifies 23 new susceptibility loci for prostate cancerQ35248192
BRCA2 is a moderate penetrance gene contributing to young-onset prostate cancer: implications for genetic testing in prostate cancer patientsQ35527158
Implications of polygenic risk-stratified screening for prostate cancer on overdiagnosisQ35602297
Multiple novel prostate cancer susceptibility signals identified by fine-mapping of known risk loci among EuropeansQ35646703
Risk Analysis of Prostate Cancer in PRACTICAL, a Multinational Consortium, Using 25 Known Prostate Cancer Susceptibility LociQ35815958
Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.Q35940158
Germline BRCA1 mutations increase prostate cancer riskQ35949522
Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancerQ35957703
Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancerQ35996692
Reducing overdiagnosis by polygenic risk-stratified screening: findings from the Finnish section of the ERSPC.Q36295073
Prediction of breast cancer risk based on profiling with common genetic variantsQ36583004
Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer riskQ36720814
Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancersQ36742577
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancerQ36859142
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancerQ36897003
The role of BRCA1 and BRCA2 in prostate cancerQ37037789
Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.Q37367871
P433issue20
P407language of work or nameEnglishQ1860
P921main subjectBRCA1 MutationQ28444960
BRCA2 MutationQ28444961
P304page(s)2240-2250
P577publication date2017-04-27
P1433published inJournal of Clinical OncologyQ400292
P1476titlePrediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores
P478volume35

Reverse relations

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