Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers

scientific article

Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/JNCI/DJW302
P932PMC publication ID5408990
P698PubMed publication ID28376175

P50authorJan LubińskiQ11718282
Olufunmilayo OlopadeQ7088836
Dominique Stoppa-LyonnetQ16629677
Georgia Chenevix-TrenchQ17517031
Kenneth OffitQ20732365
Shirley HodgsonQ15995134
Miguel de la HoyaQ60551322
Diana EcclesQ61756107
Paul D P PharoahQ61822938
Susan M DomchekQ62515230
Edith OlahQ62560279
Alfons MeindlQ63015490
Fergus J. CouchQ63018779
Susan L NeuhausenQ63019538
Jeffrey N WeitzelQ63032640
Lesley McGuffogQ63233438
Barbara WappenschmidtQ63444312
Debra FrostQ64516041
Jacques SimardQ64516110
Irene L AndrulisQ64516140
Rita SchmutzlerQ21264574
Eitan FriedmanQ21789571
Rosalind EelesQ24640445
Ute HamannQ28484017
Kristiina AittomäkiQ29840622
Heli NevanlinnaQ29840669
Lenka ForetováQ30830691
Amanda SpurdleQ45904058
Susan J. RamusQ45906365
Fabienne LesueurQ50636993
Mark RobsonQ51026477
Sylvie MazoyerQ55136930
Melissa C. SoutheyQ55446228
Maria Adelaide CaligoQ56065914
Florentia FostiraQ56246077
Christoph EngelQ56261483
Paolo RadiceQ37372139
Joan BrunetQ37378402
Riccardo DolcettiQ37378489
Irene KonstantopoulouQ38299807
Amanda Ewart TolandQ38300105
Raymonda Varon-MateevaQ38301032
Christine Rappaport-FuerhauserQ38302911
Manuel R. TeixeiraQ41584388
Julian Weldon AdlardQ42687656
kConFab InvestigatorsQ42807245
Anne-Marie GerdesQ43376223
Norbert ArnoldQ43506746
Shan Wang-GohrkerQ30831711
Karoline KuchenbaeckerQ37076233
Hanne Meijers-HeijboerQ37358732
Paolo PeterlongoQ37361857
Katherine L NathansonQ37369859
Conxi LázaroQ64856423
Marc TischkowitzQ66439010
Bent EjlertsenQ66471619
Ava KwongQ67423533
Gad RennertQ67945506
Gord GlendonQ73633107
Mary Beth TerryQ75067963
Elizabeth J van RensburgQ77789893
Marco MontagnaQ87215039
Torben A KruseQ87518225
Karin KastQ87624397
Jackie CookQ87691893
Margreet G AusemsQ87836182
Lisa GolmardQ87846280
Eric HahnenQ88011049
Matti RookusQ88943686
Soo Hwang TeoQ89171700
Encarna B Gómez GarcíaQ89224652
Åke BorgQ89371995
Angela R BradburyQ89545557
Antonis C AntoniouQ89766295
Andrew K GodwinQ89896596
Peter J HulickQ90242007
Claudine IsaacsQ90579511
Grzegorz Mariusz SukiennickiQ91036483
Jacek GronwaldQ91084015
Christian F SingerQ91125264
Evgeny N ImyanitovQ91142294
Bernd DworniczakQ91271704
David GoldgarQ91793745
Susan L SlagerQ92530010
Yael LaitmanQ92832133
Banu ArunQ93057082
Inge Søkilde PedersenQ93111381
Jocelyne ChiquetteQ95613154
Beth KarlanQ95982319
Louise IzattQ95987963
Frans HogervorstQ95989542
Mary B. DalyQ96105692
Valeria PensottiQ97414997
Monica BarileQ98148299
Penny SoucyQ98148364
Marion PiedmonteQ98148367
Carole BrewerQ98148371
Andrea GehrigQ98148373
GEMO Study CollaboratorsQ98148395
Johanna RantalaQ98150635
Antonella SavareseQ100738169
Vanesa García-BarberánQ101050010
Robert L. NussbaumQ102313438
Saundra S. BuysQ109562977
Thomas V O HansenQ114122103
Mads ThomassenQ114122189
Cecilia M DorflingQ114137304
Georg PfeilerQ114137310
Muy-Kheng TeaQ114137312
Brita ArverQ114137317
Bruce PoppeQ114166160
Rosa B BarkardottirQ114188703
Ans M W van den OuwelandQ114292607
Hereditary Breast and Ovarian Cancer Research Group NetherlandsQ114292628
Michael J LushQ114292657
Sue Kyung ParkQ114329424
Simona AgataQ114337481
EMBRACE CollaboratorsQ114337483
Yuan Chun DingQ114337484
Curtis OlswoldQ114337523
Raanan BergerQ114337558
Emily HallbergQ114337585
Laure BarjhouxQ114337610
Rosemarie DavidsonQ114337667
Fiona LallooQ114337685
Mark H GreeneQ56435504
Laura PapiQ56494593
Jacopo AzzolliniQ56524223
Daniel BarrowdaleQ56524229
Orland DiezQ56524234
Bernard PeisselQ56551029
Siranoush ManoukianQ56697298
Alex TeuléQ56855834
Javier BenitezQ56856067
Nasim MavaddatQ56875622
Joe DennisQ56875626
Vijai JosephQ56875726
Patricia GanzQ57838486
Christi J van AsperenQ58235238
Anna JakubowskaQ58323317
Anna Marie MulliganQ59659727
Esther M. JohnQ59752419
Douglas F. EastonQ59812154
Pragna GaddamQ114337735
Carolien M KetsQ114337736
Kai-Ren OngQ114337737
Emmanuelle Barouk-SimonetQ114456308
Camille ElanQ114579184
Jenny LesterQ115727450
P2093author name stringPaul James
Ana Osorio
Andrew Lee
J L de Lange
Steve Ellis
Susan M Domchek
Theo A M van Os
Wendy K Chung
Jennifer T Loud
Giuseppe Giannini
Jan Hauke
Joanna Sokolowska
John L Hays
Gustavo C Rodriguez
Marie-Agnes Collonge-Rame
Kathleen B M Claes
Nancy Cohen
Julie Martyn
William Lawler
Bernando Bonanni
Deiter Niederacher
Hans Ehrancrona
Helena C. van Doorn
Jan C. Oosterwijk
Katarzyna Kaczmarek
Rita Katherina Schmutzler
Uffe Birk Jenson
P2860cites workHazard rate ratio and prospective epidemiological studiesQ64048933
Increased mortality for neurological and mental diseases following early bilateral oophorectomyQ24645015
Increased cardiovascular mortality after early bilateral oophorectomyQ24658403
Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer riskQ27008356
PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGSQ28584533
Large-scale genotyping identifies 41 new loci associated with breast cancer riskQ29416989
GenABEL: an R library for genome-wide association analysisQ29614587
Cost-effectiveness of preventive strategies for women with a BRCA1 or a BRCA2 mutationQ44317248
Cancer risks for BRCA1 and BRCA2 mutation carriers: results from prospective analysis of EMBRACE.Q44946113
Multifactorial analysis of differences between sporadic breast cancers and cancers involving BRCA1 and BRCA2 mutationsQ47696751
Uptake of risk-reducing surgery in unaffected women at high risk of breast and ovarian cancer is risk, age, and time dependent.Q48492187
Effect of bilateral oophorectomy on women's long-term healthQ37585315
Incorporating genomics into breast and prostate cancer screening: assessing the implicationsQ37614763
Genetic modifiers of cancer risk for BRCA1 and BRCA2 mutation carriersQ37834134
Familial breast cancer: summary of updated NICE guidanceQ44126159
Counselling framework for moderate-penetrance cancer-susceptibility mutationsQ33911135
Clinical management of hereditary breast cancer syndromesQ34167563
Evaluating the yield of medical testsQ34277948
Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk predictionQ34394665
Survival patterns after oophorectomy in premenopausal women: a population-based cohort study.Q34570292
Increased risk of cognitive impairment or dementia in women who underwent oophorectomy before menopauseQ34673158
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Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer riskQ35102646
Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriersQ35523236
Identification of six new susceptibility loci for invasive epithelial ovarian cancerQ35541663
Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)Q35737888
Risk Analysis of Prostate Cancer in PRACTICAL, a Multinational Consortium, Using 25 Known Prostate Cancer Susceptibility LociQ35815958
Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.Q35940158
Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancerQ35996692
Prediction of breast cancer risk based on profiling with common genetic variantsQ36583004
The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensionsQ36615665
Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer riskQ36720814
Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancersQ36742577
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancerQ36897003
Identification of personal risk of breast cancer: geneticsQ37039765
Meta-analysis of risk reduction estimates associated with risk-reducing salpingo-oophorectomy in BRCA1 or BRCA2 mutation carriersQ37090813
Prediction of breast cancer risk by genetic risk factors, overall and by hormone receptor statusQ37223335
Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.Q37367871
A weighted cohort approach for analysing factors modifying disease risks in carriers of high-risk susceptibility genesQ81725988
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectovarian cancerQ172341
BRCA1 MutationQ28444960
P577publication date2017-07-01
P1433published inJournal of the National Cancer InstituteQ400279
P1476titleEvaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers
P478volume109

Reverse relations

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