Common Genetic Variation and Breast Cancer Risk - Past, present, and future

scientific article published on 30 January 2018

Common Genetic Variation and Breast Cancer Risk - Past, present, and future is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1158/1055-9965.EPI-17-1144
P932PMC publication ID5884707
P698PubMed publication ID29382703

P50authorFergus J. CouchQ63018779
Celine M. VachonQ74173260
P2093author name stringJenna Lilyquist
Kathryn J Ruddy
P2860cites workDNA glycosylases involved in base excision repair may be associated with cancer risk in BRCA1 and BRCA2 mutation carriersQ21144874
PALB2, which encodes a BRCA2-interacting protein, is a breast cancer susceptibility geneQ24615080
Genome-wide association studies identify four ER negative-specific breast cancer risk lociQ24622610
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Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriersQ24655824
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A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1Q28115843
Low-penetrance susceptibility to breast cancer due to CHEK2(*)1100delC in noncarriers of BRCA1 or BRCA2 mutationsQ28215462
A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancerQ28303909
Genome-wide association study in east Asians identifies novel susceptibility loci for breast cancerQ28924377
Large-scale genotyping identifies 41 new loci associated with breast cancer riskQ29416989
Genetic modifiers of CHEK2*1100delC-associated breast cancer riskQ37739048
Long Noncoding RNAs CUPID1 and CUPID2 Mediate Breast Cancer Risk at 11q13 by Modulating the Response to DNA Damage.Q38640565
Health Disparities and Triple-Negative Breast Cancer in African American Women: A ReviewQ38868959
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Genome-wide association studies in women of African ancestry identified 3q26.21 as a novel susceptibility locus for oestrogen receptor negative breast cancerQ40346126
Genetic variations in the Hippo signaling pathway and breast cancer risk in African American women in the AMBER ConsortiumQ40638709
Genetic susceptibility to breast cancerQ41130542
Rates for breast cancer characteristics by estrogen and progesterone receptor status in the major racial/ethnic groupsQ44121727
Association of a common variant of the CASP8 gene with reduced risk of breast cancerQ45188733
Association analysis identifies 65 new breast cancer risk loci.Q45979098
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancerQ46103372
Joint associations of a polygenic risk score and environmental risk factors for breast cancer in the Breast Cancer Association ConsortiumQ47190168
The associations of sequence variants in DNA-repair and cell-cycle genes with cancer risk: genotype-phenotype correlations.Q47800993
High constant incidence in twins and other relatives of women with breast cancer.Q53403578
A common coding variant in CASP8 is associated with breast cancer riskQ57250674
Common variants on chromosome 5p12 confer susceptibility to estrogen receptor–positive breast cancerQ57251792
Discriminatory accuracy from single-nucleotide polymorphisms in models to predict breast cancer riskQ36858843
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancerQ36859142
An evaluation of the polymorphisms Ins16bp and Arg72Pro in p53 as breast cancer risk modifiers in BRCA1 and BRCA2 mutation carriersQ36882665
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancerQ36897003
Gene-based analysis of the fibroblast growth factor receptor signaling pathway in relation to breast cancer in African American women: the AMBER consortiumQ36961082
CHEK2*1100delC genotyping for clinical assessment of breast cancer risk: meta-analyses of 26,000 patient cases and 27,000 controlsQ37048943
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Admixture Mapping of African-American Women in the AMBER Consortium Identifies New Loci for Breast Cancer and Estrogen-Receptor SubtypesQ37271961
Beyond GWASs: illuminating the dark road from association to functionQ37298148
Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 RegulationQ37342144
Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.Q37356243
Fine-scale mapping of the FGFR2 breast cancer risk locus: putative functional variants differentially bind FOXA1 and E2F1.Q37367871
Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1.Q37369631
Genetic variations in vitamin D-related pathways and breast cancer risk in African American women in the AMBER consortiumQ37381735
The TP53 Arg72Pro and MDM2 309G>T polymorphisms are not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriersQ37401496
Common variants in LSP1, 2q35 and 8q24 and breast cancer risk for BRCA1 and BRCA2 mutation carriersQ37434133
Evaluation of a candidate breast cancer associated SNP in ERCC4 as a risk modifier in BRCA1 and BRCA2 mutation carriers. Results from the Consortium of Investigators of Modifiers of BRCA1/BRCA2 (CIMBA).Q37481884
Genetic variation in the insulin, insulin-like growth factor, growth hormone, and leptin pathways in relation to breast cancer in African-American women: the AMBER consortiumQ37482022
A collaborative study of the etiology of breast cancer subtypes in African American women: the AMBER consortiumQ37623331
Genome-wide association study identifies 25 known breast cancer susceptibility loci as risk factors for triple-negative breast cancerQ29417100
Identification of the breast cancer susceptibility gene BRCA2Q29616290
Breast Cancer Screening in the Precision Medicine Era: Risk-Based Screening in a Population-Based Trial.Q30238753
Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristicsQ33330850
Cis-eQTL-based trans-ethnic meta-analysis reveals novel genes associated with breast cancer risk.Q33565679
Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation CarriersQ33614244
A functionally significant SNP in TP53 and breast cancer risk in African-American womenQ33731355
Fine scale mapping of the breast cancer 16q12 locusQ33878276
CHEK2*1100delC and susceptibility to breast cancer: a collaborative analysis involving 10,860 breast cancer cases and 9,065 controls from 10 studiesQ33910280
Gene-environment interactions in 7610 women with breast cancer: prospective evidence from the Million Women StudyQ33935171
Common variants associated with breast cancer in genome-wide association studies are modifiers of breast cancer risk in BRCA1 and BRCA2 mutation carriersQ33947829
Genome-wide association analysis in East Asians identifies breast cancer susceptibility loci at 1q32.1, 5q14.3 and 15q26.1.Q34023796
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Population structure in admixed populations: effect of admixture dynamics on the pattern of linkage disequilibrium.Q34043712
A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1).Q34085748
Genome-wide association study identifies five new breast cancer susceptibility lociQ34114293
A comprehensive examination of breast cancer risk loci in African American womenQ34211808
Evaluating genome-wide association study-identified breast cancer risk variants in African-American womenQ34339783
Common non-synonymous SNPs associated with breast cancer susceptibility: findings from the Breast Cancer Association ConsortiumQ34379032
ATM mutations that cause ataxia-telangiectasia are breast cancer susceptibility allelesQ34546389
A genome-wide scan for breast cancer risk haplotypes among African American womenQ34611972
An international initiative to identify genetic modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: the Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA)Q34623703
Common variants on chromosomes 2q35 and 16q12 confer susceptibility to estrogen receptor-positive breast cancerQ34631785
Association of the variants CASP8 D302H and CASP10 V410I with breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriersQ34801008
Evaluation of the XRCC1 gene as a phenotypic modifier in BRCA1/2 mutation carriers. Results from the consortium of investigators of modifiers of BRCA1/BRCA2.Q34806825
Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer riskQ35061252
Evidence that breast cancer risk at the 2q35 locus is mediated through IGFBP5 regulationQ35064451
A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general populationQ35089479
Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer riskQ35102646
Genetic predisposition to in situ and invasive lobular carcinoma of the breastQ35151684
Fine-mapping of breast cancer susceptibility loci characterizes genetic risk in African AmericansQ35389444
Replication of breast cancer GWAS susceptibility loci in the Women's Health Initiative African American SHARe StudyQ35456134
Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriersQ35523236
Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2.Q35524465
Genome-wide association study identifies breast cancer risk variant at 10q21.2: results from the Asia Breast Cancer ConsortiumQ35565707
Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)Q35737888
Novel Associations between Common Breast Cancer Susceptibility Variants and Risk-Predicting Mammographic Density MeasuresQ35752042
A common variant at the TERT-CLPTM1L locus is associated with estrogen receptor-negative breast cancerQ35755874
19p13.1 is a triple-negative-specific breast cancer susceptibility locusQ35871567
Evaluation of 19 susceptibility loci of breast cancer in women of African ancestryQ35883587
Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2.Q35889575
Common breast cancer susceptibility loci are associated with triple-negative breast cancerQ35891162
Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170.Q35940158
Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancerQ35996692
Mammographic breast density and breast cancer: evidence of a shared genetic basisQ36043843
Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 ExpressionQ36066735
An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expressionQ36073563
Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locusQ36124728
The contributions of breast density and common genetic variation to breast cancer riskQ36137764
A nonsynonymous polymorphism in IRS1 modifies risk of developing breast and ovarian cancers in BRCA1 and ovarian cancer in BRCA2 mutation carriersQ36152991
Evaluation of chromosome 6p22 as a breast cancer risk modifier locus in a follow-up study of BRCA2 mutation carriersQ36352389
Common variants at 12p11, 12q24, 9p21, 9q31.2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2 mutation carriersQ36393232
A meta-analysis of genome-wide association studies of breast cancer identifies two novel susceptibility loci at 6q14 and 20q11.Q36435849
RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studiesQ36512097
Genetic susceptibility loci for subtypes of breast cancer in an African American populationQ36514074
Prediction of breast cancer risk based on profiling with common genetic variantsQ36583004
Fine-mapping of the 6q25 locus identifies a novel SNP associated with breast cancer risk in African-American womenQ36587625
Breast Cancer Risk Prediction Using Clinical Models and 77 Independent Risk-Associated SNPs for Women Aged Under 50 Years: Australian Breast Cancer Family RegistryQ36619329
Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer riskQ36720814
Evidence of gene-environment interactions between common breast cancer susceptibility loci and established environmental risk factorsQ36720821
Functional variants at the 11q13 risk locus for breast cancer regulate cyclin D1 expression through long-range enhancersQ36742577
Family history, age, and risk of breast cancer. Prospective data from the Nurses' Health StudyQ36743855
Common alleles at 6q25.1 and 1p11.2 are associated with breast cancer risk for BRCA1 and BRCA2 mutation carriersQ36839777
Genome-wide association analysis identifies three new breast cancer susceptibility lociQ36842233
Common genetic determinants of breast-cancer risk in East Asian women: a collaborative study of 23 637 breast cancer cases and 25 579 controlsQ36856357
P921main subjectgenetic variationQ349856
P577publication date2018-01-30
P1433published inCancer Epidemiology, Biomarkers & PreventionQ326334
P1476titleCommon Genetic Variation and Breast Cancer Risk - Past, present, and future

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cites work (P2860)
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