Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants (scientific article published on 15 July 2020)

Average risks of breast and ovarian cancer associated with BRCA1 or BRCA2 mutations detected in case Series unselected for family history: a combined analysis of 22 studies

Q24531993

Common breast cancer-predisposition alleles are associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers

Q24655824

Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk

Q27008356

Association analysis identifies 65 new breast cancer risk loci.

Q45979098

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer

Q46103372

Evaluation of association methods for analysing modifiers of disease risk in carriers of high-risk mutations.

Q52887813

A response to "Personalised medicine and population health: breast and ovarian cancer"

Q91960210

Polygenic prediction of breast cancer: comparison of genetic predictors and implications for risk stratification

Q92638472

Prediction of breast cancer risk based on profiling with common genetic variants

Q36583004

The BOADICEA model of genetic susceptibility to breast and ovarian cancers: updates and extensions

Q36615665

Identification of a BRCA2-specific modifier locus at 6p24 related to breast cancer risk

Q36720814

Quantifying and correcting for the winner's curse in genetic association studies

Q37251769

BOADICEA breast cancer risk prediction model: updates to cancer incidences, tumour pathology and web interface

Q37507410

Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers

Q38717239

Evaluation of polygenic risk scores for ovarian cancer risk prediction in a prospective cohort study

Q57172770

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

Q62583133

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

Q30252854

Covariate-adjusted measures of discrimination for survival data

Q30881367

Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers

Q33614244

Variation in cancer risks, by mutation position, in BRCA2 mutation carriers

Q34044197

Evaluating the yield of medical tests

Q34277948

Common breast cancer susceptibility alleles and the risk of breast cancer for BRCA1 and BRCA2 mutation carriers: implications for risk prediction

Q34394665

An international initiative to identify genetic modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: the Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA)

Q34623703

Pathology of breast and ovarian cancers among BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)

Q35737888

Pathology of ovarian cancers in BRCA1 and BRCA2 carriers

Q35741630

Association of type and location of BRCA1 and BRCA2 mutations with risk of breast and ovarian cancer

Q35957703

RAD51 135G-->C modifies breast cancer risk among BRCA2 mutation carriers: results from a combined analysis of 19 studies

Q36512097

BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors

Q91045517

A weighted cohort approach for analysing factors modifying disease risks in carriers of high-risk susceptibility genes

Q81725988

P921

main subject

ovarian cancer

Q172341

P577

publication date

2020-07-15

P1433

published in

Genetics in Medicine

Q15765508

P1476

title

Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants