scholarly article | Q13442814 |
P50 | author | Todd Waldman | Q96147120 |
P2093 | author name string | C David James | |
Jung-Sik Kim | |||
Victoria K Hill | |||
P2860 | cites work | The lipid phosphatase activity of PTEN is critical for its tumor supressor function | Q22007981 |
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex | Q24295120 | ||
Mechanism of activation of protein kinase B by insulin and IGF-1 | Q24309528 | ||
The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate | Q24317714 | ||
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase | Q24322705 | ||
Comprehensive genomic characterization defines human glioblastoma genes and core pathways | Q24656128 | ||
A panel of isogenic human cancer cells suggests a therapeutic approach for cancers with inactivated p53 | Q24657532 | ||
AKT/PKB signaling: navigating downstream | Q24657857 | ||
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice | Q58378937 | ||
Integrative clinical genomics of advanced prostate cancer | Q27853170 | ||
Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer | Q28251814 | ||
SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity | Q28262782 | ||
Integrated genomic characterization of endometrial carcinoma | Q28289962 | ||
The somatic genomic landscape of glioblastoma | Q28300185 | ||
Mutational landscape and significance across 12 major cancer types | Q28300353 | ||
Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers | Q28306997 | ||
Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems | Q28586004 | ||
Functional evaluation of PTEN missense mutations using in vitro phosphoinositide phosphatase assay | Q28611936 | ||
The functions and regulation of the PTEN tumour suppressor | Q29615536 | ||
Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome | Q29615538 | ||
PTEN: a tumour suppressor that functions as a phospholipid phosphatase | Q33594251 | ||
Cellular transformation by the MSP58 oncogene is inhibited by its physical interaction with the PTEN tumor suppressor | Q33863959 | ||
PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome | Q34504165 | ||
Germline mutations in the PTEN/MMAC1 gene in patients with Cowden disease. | Q34742581 | ||
PTEN hamartoma tumor syndromes. | Q34824223 | ||
Subtle variations in Pten dose determine cancer susceptibility | Q35055350 | ||
Mechanistic analysis of a DNA damage-induced, PTEN-dependent size checkpoint in human cells | Q35096583 | ||
Mutational inactivation of STAG2 causes aneuploidy in human cancer | Q36029045 | ||
Epitope tagging of endogenous genes in diverse human cell lines | Q36959684 | ||
Combating trastuzumab resistance by targeting SRC, a common node downstream of multiple resistance pathways | Q37425090 | ||
PTEN function: the long and the short of it. | Q38198345 | ||
A new class of cancer-associated PTEN mutations defined by membrane translocation defects | Q38952567 | ||
Tumor suppression by PTEN requires the activation of the PKR-eIF2alpha phosphorylation pathway | Q39759975 | ||
Characterization of two new permanent glioma cell lines 8-MG-BA and 42-MG-BA. | Q41038971 | ||
Identification of the JNK signaling pathway as a functional target of the tumor suppressor PTEN. | Q42807109 | ||
Next-generation Akt inhibitors provide greater specificity: effects on glucose metabolism in adipocytes. | Q42814165 | ||
Germline mutations in PTEN are present in Bannayan-Zonana syndrome | Q48046915 | ||
Somatic mutations of PTEN in glioblastoma multiforme | Q48618632 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 5 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | glioblastoma | Q282142 |
P304 | page(s) | e0176683 | |
P577 | publication date | 2017-05-02 | |
P1433 | published in | PLOS One | Q564954 |
P1476 | title | Correction of PTEN mutations in glioblastoma cell lines via AAV-mediated gene editing | |
P478 | volume | 12 |
Q90641009 | AEBP1 down regulation induced cell death pathway depends on PTEN status of glioma cells |
Q47136308 | Apoptotic Signaling Pathways in Glioblastoma and Therapeutic Implications |
Q92445464 | Detection and Correlation of Single and Concomitant TP53, PTEN, and CDKN2A Alterations in Gliomas |
Q93052506 | Quality Control Strategy for CRISPR-Cas9-Based Gene Editing Complicated by a Pseudogene |
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