An anti-platelet-endothelial cell adhesion molecule-1 antibody inhibits leukocyte extravasation from mesenteric microvessels in vivo by blocking the passage through the basement membrane

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An anti-platelet-endothelial cell adhesion molecule-1 antibody inhibits leukocyte extravasation from mesenteric microvessels in vivo by blocking the passage through the basement membrane is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1084/JEM.184.1.229
P932PMC publication ID2192663
P698PubMed publication ID8691137
P5875ResearchGate publication ID14511394

P50authorMaria J SanzQ57252368
P2093author name stringS Nourshargh
T J Williams
S M Albelda
A Dewar
S W Larkin
M W Wakelin
N Boughton-Smith
P2860cites workSelectinsQ24602099
Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion moleculeQ24644205
Integrins: versatility, modulation, and signaling in cell adhesionQ27860844
Involvement of platelet-endothelial cell adhesion molecule-1 in neutrophil recruitment in vivoQ28576817
Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigmQ29547181
Recognition of an endothelial determinant for CD 18-dependent human neutrophil adherence and transendothelial migrationQ35593510
Recruitment of CD11b/CD18 to the neutrophil surface and adherence-dependent cell locomotionQ35608005
CD31 expressed on distinctive T cell subsets is a preferential amplifier of beta 1 integrin-mediated adhesionQ36231539
The integrin VLA-4 supports tethering and rolling in flow on VCAM-1.Q36235481
Human neutrophil adherence to laminin in vitro. Evidence for a distinct neutrophil integrin receptor for lamininQ36350914
A human endothelial cell-restricted, externally disposed plasmalemmal protein enriched in intercellular junctionsQ36356682
PECAM-1 is required for transendothelial migration of leukocytesQ36362038
Monoclonal antibody to murine PECAM-1 (CD31) blocks acute inflammation in vivoQ36362908
Migration of monocytes across endothelium and passage through extracellular matrix involve separate molecular domains of PECAM-1Q36365479
Neutrophil migration across monolayers of cytokine-prestimulated endothelial cells: a role for platelet-activating factor and IL-8Q36531315
Ligation of platelet/endothelial cell adhesion molecule 1 (PECAM-1/CD31) on monocytes and neutrophils increases binding capacity of leukocyte CR3 (CD11b/CD18).Q41389041
Murine platelet endothelial cell adhesion molecule (PECAM-1)/CD31 modulates beta 2 integrins on lymphokine-activated killer cellsQ41522290
Mapping the homotypic binding sites in CD31 and the role of CD31 adhesion in the formation of interendothelial cell contactsQ41844323
Evidence that a receptor-operated event on the neutrophil mediates neutrophil accumulation in vivo. Pretreatment of 111In-neutrophils with pertussis toxin in vitro inhibits their accumulation in vivo.Q44402762
Differential utilization of ICAM-1 and VCAM-1 during the adhesion and transendothelial migration of human T lymphocytesQ45086854
alpha 4 integrins mediate lymphocyte attachment and rolling under physiologic flowQ46523925
Cytokine-activated human endothelial monolayers support enhanced neutrophil transmigration via a mechanism involving both endothelial-leukocyte adhesion molecule-1 and intercellular adhesion molecule-1Q67681256
Regulation of Rransendothelial Neutrophil Migration by Endogenous Interleukin-8Q67701914
CD11/CD18-independent neutrophil adherence to laminin is mediated by the integrin VLA-6Q67880616
Eosinophil transendothelial migration induced by cytokines. I. Role of endothelial and eosinophil adhesion molecules in IL-1 beta-induced transendothelial migrationQ67960371
L-selectin and very late antigen-4 integrin promote eosinophil rolling at physiological shear rates in vivoQ71651106
A novel beta 1-dependent adhesion pathway on neutrophils: a mechanism invoked by dihydrocytochalasin B or endothelial transmigrationQ71706884
Interleukin-1-induced leukocyte extravasation across rat mesenteric microvessels is mediated by platelet-activating factorQ72184636
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectantibodyQ79460
endotheliumQ111140
cell adhesionQ187640
microvesselQ6840468
P304page(s)229-239
P577publication date1996-07-01
P1433published inJournal of Experimental MedicineQ3186912
P1476titleAn anti-platelet-endothelial cell adhesion molecule-1 antibody inhibits leukocyte extravasation from mesenteric microvessels in vivo by blocking the passage through the basement membrane
P478volume184

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cites work (P2860)
Q419553094D intravital microscopy uncovers critical strain differences for the roles of PECAM and CD99 in leukocyte diapedesis.
Q35792141A novel biological activity for galectin-1: inhibition of leukocyte-endothelial cell interactions in experimental inflammation.
Q32038548A novel model for the study of synovial microcirculation in the mouse knee joint in vivo.
Q79288233Acceleration of the onset of collagen‐induced arthritis by a deficiency of platelet endothelial cell adhesion molecule 1
Q34787599Altered vascular permeability and early onset of experimental autoimmune encephalomyelitis in PECAM-1-deficient mice
Q24676229Association between kinin B(1) receptor expression and leukocyte trafficking across mouse mesenteric postcapillary venules
Q33933296Biomechanics of cell interactions in shear fields
Q45147902Blockade of alpha6 integrin inhibits IL-1beta- but not TNF-alpha-induced neutrophil transmigration in vivo
Q44623026CD31 Regulates Direction and Rate of Neutrophil Migration over and under Endothelial Cells
Q54331256CD31, EDNRB and TSPAN7 are promising prognostic markers in clear-cell renal cell carcinoma revealed by genome-wide expression analyses of primary tumors and metastases.
Q42982677Cell adhesion molecules involved in the leukocyte recruitment induced by venom of the snake Bothrops jararaca.
Q36782030Change in platelet endothelial cell adhesion molecule-1 immunoreactivity in the dentate gyrus in gerbils fed a folate-deficient diet
Q41847767Characterization of the 4C8 antigen involved in transendothelial migration of CD26(hi) T cells after tight adhesion to human umbilical vein endothelial cell monolayers
Q37580117Collagen-based cell migration models in vitro and in vivo
Q44691593Critical role of CXC chemokines in endotoxemic liver injury in mice
Q73258026Cross-talk between cell adhesion molecules regulates the migration velocity of neutrophils
Q28564978Dexamethasone inhibition of leucocyte adhesion to rat mesenteric postcapillary venules: role of intercellular adhesion molecule 1 and KC
Q22254128Differential ability of exogenous chemotactic agents to disrupt transendothelial migration of flowing neutrophils
Q32044975Disease-modifying activity of SB 273005, an orally active, nonpeptide alphavbeta3 (vitronectin receptor) antagonist, in rat adjuvant-induced arthritis
Q36228711ESAM supports neutrophil extravasation, activation of Rho, and VEGF-induced vascular permeability
Q39637656Effects of the prebiotics inulin and lactulose on intestinal immunology and hematology of preruminant calves.
Q46919125Endothelial basement membrane laminin alpha5 selectively inhibits T lymphocyte extravasation into the brain
Q30439713Endothelial cell PECAM-1 promotes atherosclerotic lesions in areas of disturbed flow in ApoE-deficient mice
Q41322935Endothelial cell activation leads to neutrophil transmigration as supported by the sequential roles of ICAM-2, JAM-A, and PECAM-1.
Q40694542Expression pattern of alternatively spliced PECAM-1 isoforms in hematopoietic cells and platelets
Q46623974Fast flowing eosinophils: signals for stopping and stepping out of blood vessels
Q36772662Getting leukocytes to the site of inflammation
Q36641150HGF/SF and its receptor c-MET play a minor role in the dissemination of human B-lymphoma cells in SCID mice
Q38608338How leukocytes cross the vascular endothelium
Q77419177Human eotaxin induces eosinophil extravasation through rat mesenteric venules: role of alpha4 integrins and vascular cell adhesion molecule-1
Q28145696Identification and characterisation of human Junctional Adhesion Molecule (JAM)
Q48099738Increased serum levels of soluble PECAM-1 in multiple sclerosis patients with brain gadolinium-enhancing lesions
Q28084855Inflammatory mediators in vascular disease: identifying promising targets for intracranial aneurysm research
Q36526980Influence of ultra-low dose Aprotinin on thoracic surgical operations: a prospective randomized trial
Q33631950Inhibition of leukocyte adhesion by developmental endothelial locus-1 (del-1).
Q36367396Interferon gamma regulates platelet endothelial cell adhesion molecule 1 expression and neutrophil infiltration into herpes simplex virus-infected mouse corneas
Q42087882Involvement of endothelial PECAM-1/CD31 in angiogenesis.
Q35684128Isolation of Foreign Material-Free Endothelial Progenitor Cells Using CD31 Aptamer and Therapeutic Application for Ischemic Injury
Q33695206Lactosylceramide recruits PKCalpha/epsilon and phospholipase A2 to stimulate PECAM-1 expression in human monocytes and adhesion to endothelial cells
Q29544231Leukocyte-endothelial cell adhesion: avenues for therapeutic intervention
Q34633418Leukocyte-endothelial cell interactions in the inflammatory response
Q28179659Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response
Q36772665Mechanisms of Leukocyte Transendothelial Migration
Q37336596Mechanisms of transendothelial migration of leukocytes
Q35891216Mini-review: Transendothelial migration of leukocytes: through the front door or around the side of the house?
Q35745956PECAM-1 (CD31) expression modulates bleeding time in vivo
Q36371472PECAM-1 (CD31) homophilic interaction up-regulates alpha6beta1 on transmigrated neutrophils in vivo and plays a functional role in the ability of alpha6 integrins to mediate leukocyte migration through the perivascular basement membrane
Q64071660PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation
Q35690784PECAM-1 dampens cytokine levels during LPS-induced endotoxemia by regulating leukocyte trafficking
Q36473318PECAM-1 isoforms, eNOS and endoglin axis in regulation of angiogenesis
Q83207652Platelet Endothelial Cell Adhesion Molecule 1 (PECAM-1/CD31): A Multifunctional Vascular Cell Adhesion Molecule
Q35584864Platelet endothelial cell adhesion molecule in cell signaling and thrombosis
Q74602793Platelet-endothelial cell adhesion molecule-1 (CD31) redistributes from the endothelial junction and is not required for the transendothelial migration of melanoma cells
Q33947142Regulation of endothelial cell barrier function by antibody-driven affinity modulation of platelet endothelial cell adhesion molecule-1 (PECAM-1)
Q34858216Regulation of endothelial cell contacts during leukocyte extravasation
Q34808655Relative contribution of PECAM-1 adhesion and signaling to the maintenance of vascular integrity.
Q28645282Residues on both faces of the first immunoglobulin fold contribute to homophilic binding sites of PECAM-1/CD31
Q35923917Rho GTPases and leucocyte-induced endothelial remodelling
Q36491844RhoA activation and actin reorganization involved in endothelial CAM-mediated endocytosis of anti-PECAM carriers: critical role for tyrosine 686 in the cytoplasmic tail of PECAM-1.
Q47755806Role for platelet-endothelial cell adhesion molecule-1 in macrophage Fcgamma receptor function
Q36826098Shedding of PECAM-1 during HIV infection: a potential role for soluble PECAM-1 in the pathogenesis of NeuroAIDS.
Q35946607Short-term sPECAM-Fc treatment ameliorates EAE while chronic use hastens onset of symptoms
Q36377077Soluble domain 1 of platelet-endothelial cell adhesion molecule (PECAM) is sufficient to block transendothelial migration in vitro and in vivo
Q40458458Statin-inhibited endothelial permeability could be associated with its effect on PECAM-1 in endothelial cells.
Q36956344Stepping out of the flow: capillary extravasation in cancer metastasis
Q36773552The anti-inflammatory actions of platelet endothelial cell adhesion molecule-1 do not involve regulation of endothelial cell NF-kappa B.
Q37778548The blood–brain barrier, chemokines and multiple sclerosis
Q28294058The impact of the extracellular matrix on inflammation
Q48473163sPECAM-1 in serum and CSF of acute ischaemic stroke patients

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