Notch1 deficiency dissociates the intrathymic development of dendritic cells and T cells.

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Notch1 deficiency dissociates the intrathymic development of dendritic cells and T cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1084/JEM.191.7.1085
P932PMC publication ID2193172
P698PubMed publication ID10748227
P5875ResearchGate publication ID236239363

P50authorFreddy RadtkeQ41621239
P2093author name stringA Wilson
M Aguet
I Ferrero
H R MacDonald
R Lees
P2860cites workExpression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell developmentQ22010181
Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch geneQ24336592
Dendritic cells and the control of immunityQ27860918
Notch signaling: cell fate control and signal integration in developmentQ27861061
The human homolog of rat Jagged1 expressed by marrow stroma inhibits differentiation of 32D cells through interaction with Notch1Q28261520
Jagged: A mammalian ligand that activates notch1Q28298760
Notch2: a second mammalian Notch geneQ28568315
Jagged2: a serrate-like gene expressed during rat embryogenesisQ28580835
A homolog of Drosophila Notch expressed during mammalian developmentQ28581406
Mouse Dll3: a novel divergent Delta gene which may complement the function of other Delta homologues during early pattern formation in the mouse embryoQ28592518
The Ikaros gene is required for the development of all lymphoid lineagesQ28594316
The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepitheliumQ28623130
Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculationQ33588887
Regulation of T cell fate by NotchQ33652483
Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutationQ34412659
The surface phenotype of dendritic cells purified from mouse thymus and spleen: investigation of the CD8 expression by a subpopulation of dendritic cellsQ36231530
Murine epidermal Langerhans cells mature into potent immunostimulatory dendritic cells in vitroQ36349915
Thymic dendritic cell precursors: relationship to the T lymphocyte lineage and phenotype of the dendritic cell progenyQ36367357
Inhibition of granulocytic differentiation by mNotch1.Q36686889
Developmental dissociation of thymic dendritic cell and thymocyte lineages revealed in growth factor receptor mutant miceQ36780661
Correlating notch signaling with thymocyte maturationQ37462948
Origin, maturation and antigen presenting function of dendritic cells.Q40906220
Notch1-induced delay of human hematopoietic progenitor cell differentiation is associated with altered cell cycle kineticsQ40977649
Cutting edge: protective effects of notch-1 on TCR-induced apoptosis.Q40978448
Thymic dendritic cellsQ41546347
Targeted expression of major histocompatibility complex (MHC) class II molecules demonstrates that dendritic cells can induce negative but not positive selection of thymocytes in vivoQ42113339
Distinct mechanisms of neonatal tolerance induced by dendritic cells and thymic B cellsQ42767921
Specific EGF repeats of Notch mediate interactions with Delta and serrate: Implications for notch as a multifunctional receptorQ42806879
Notch activity influences the alphabeta versus gammadelta T cell lineage decisionQ45345198
Deficient T cell fate specification in mice with an induced inactivation of Notch1.Q45345200
An activated form of Notch influences the choice between CD4 and CD8 T cell lineagesQ46109980
Identification of clonogenic common lymphoid progenitors in mouse bone marrowQ46782262
Transient and restricted expression during mouse embryogenesis of Dll1, a murine gene closely related to Drosophila DeltaQ48071652
Cloning, analysis, and chromosomal localization of Notch-1, a mouse homolog of Drosophila NotchQ48134294
Motch A and motch B--two mouse Notch homologues coexpressed in a wide variety of tissuesQ48134478
Expression analysis of a Notch homologue in the mouse embryoQ48146069
Notch1 expression in early lymphopoiesis influences B versus T lineage determination.Q51085324
The linkage between T-cell and dendritic cell development in the mouse thymus.Q52181534
Cell-autonomous defects in dendritic cell populations of Ikaros mutant mice point to a developmental relationship with the lymphoid lineage.Q52192219
Modulated expression of notch1 during thymocyte development.Q52200560
A human homologue of the Drosophila developmental gene, Notch, is expressed in CD34+ hematopoietic precursors.Q52217200
A limited role for beta-selection during gamma delta T cell development.Q52906792
Definition of dendritic cell subpopulations present in the spleen, Peyer's patches, lymph nodes, and skin of the mouseQ58436660
Thymic dendritic cells and T cells develop simultaneously in the thymus from a common precursor populationQ59056890
RelB is essential for the development of myeloid-related CD8alpha- dendritic cells but not of lymphoid-related CD8alpha+ dendritic cellsQ77769122
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectdendritic cellQ506253
P304page(s)1085-1094
P577publication date2000-04-01
P1433published inJournal of Experimental MedicineQ3186912
P1476titleNotch1 deficiency dissociates the intrathymic development of dendritic cells and T cells
P478volume191

Reverse relations

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