Model Uncertainty via the Integration of Hormesis and LNT as the Default in Cancer Risk Assessment

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Model Uncertainty via the Integration of Hormesis and LNT as the Default in Cancer Risk Assessment is …
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scholarly articleQ13442814

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P356DOI10.1177/1559325815621764
P932PMC publication ID4679205
P698PubMed publication ID26740815
P5875ResearchGate publication ID287125266

P2093author name stringEdward J Calabrese
P2860cites workRadiation hormesis: its historical foundations as a biological hypothesisQ33879968
Radiation hormesis: the demise of a legitimate hypothesisQ33879973
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The occurrence of hormetic dose responses in the toxicological literature, the hormesis database: an overviewQ36018746
Hormetic mechanismsQ38123216
Origin of the linearity no threshold (LNT) dose-response conceptQ38124218
How the US National Academy of Sciences misled the world community on cancer risk assessment: new findings challenge historical foundations of the linear dose responseQ38126376
Biphasic dose responses in biology, toxicology and medicine: accounting for their generalizability and quantitative featuresQ38132944
The Genetics Panel of the NAS BEAR I Committee (1956): epistolary evidence suggests self-interest may have prompted an exaggeration of radiation risks that led to the adoption of the LNT cancer risk assessment modelQ38226176
Cancer risk assessment: Optimizing human health through linear dose-response modelsQ38444743
On the origins of the linear no-threshold (LNT) dogma by means of untruths, artful dodges and blind faithQ38561784
The Integration of LNT and Hormesis for Cancer Risk Assessment Optimizes Public Health ProtectionQ40063654
Key studies used to support cancer risk assessment questionedQ46508420
Cancer risk assessment foundation unraveling: new historical evidence reveals that the US National Academy of Sciences (US NAS), Biological Effects of Atomic Radiation (BEAR) Committee Genetics Panel falsified the research record to promote acceptanQ48052759
An abuse of risk assessment: how regulatory agencies improperly adopted LNT for cancer risk assessmentQ48052904
Hormesis and plant biology.Q51949318
Hormesis in high-throughput screening of antibacterial compounds in E coli.Q54392158
Chemical hormesis: its historical foundations as a biological hypothesisQ73616997
The marginalization of hormesisQ73617000
GENETIC effects of atomic radiationQ74117564
The hormetic dose-response model is more common than the threshold model in toxicologyQ78873155
Hormesis outperforms threshold model in National Cancer Institute antitumor drug screening databaseQ80208299
Hormesis predicts low-dose responses better than threshold modelsQ82746430
The hormesis database: the occurrence of hormetic dose responses in the toxicological literatureQ84432510
P433issue4
P304page(s)1559325815621764
P577publication date2015-10-01
P1433published inDose-ResponseQ20181483
P1476titleModel Uncertainty via the Integration of Hormesis and LNT as the Default in Cancer Risk Assessment
P478volume13

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cites work (P2860)
Q37403662A Certified Health Physicist's Reflections on a 40-Year Career in Radiation Protection
Q38911791Biological basis of radiation protection needs rejuvenation
Q41937769Debate on the Chernobyl Disaster: Response to Alison Rosamund Katz.
Q58799336Influence of Individual Radiosensitivity on the Adaptive Response Phenomenon: Toward a Mechanistic Explanation Based on the Nucleo-Shuttling of ATM Protein
Q38864825Low-dose radiation may be a novel approach to enhance the effectiveness of cancer therapeutics
Q36283697Mechanisms and Effects of Transcranial Direct Current Stimulation
Q92098878Replacing LNT: The Integrated LNT-Hormesis Model
Q58793247The EPA Cancer Risk Assessment Default Model Proposal: Moving Away From the LNT
Q28068905The Emergence of the Dose-Response Concept in Biology and Medicine

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