Influence of Individual Radiosensitivity on the Adaptive Response Phenomenon: Toward a Mechanistic Explanation Based on the Nucleo-Shuttling of ATM Protein

scientific article published on 01 July 2018

Influence of Individual Radiosensitivity on the Adaptive Response Phenomenon: Toward a Mechanistic Explanation Based on the Nucleo-Shuttling of ATM Protein is …
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scholarly articleQ13442814

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P356DOI10.1177/1559325818789836
P932PMC publication ID6081762
P698PubMed publication ID30093841

P50authorNicolas ForayQ88655667
P2093author name stringClément Devic
Mélanie L Ferlazzo
P2860cites workATM-dependent hyper-radiosensitivity in mammalian cells irradiated by heavy ionsQ41937732
A low, adaptive dose of gamma-rays reduced the number and altered the spectrum of S1- mutants in human-hamster hybrid AL cellsQ42813644
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Human lymphocytes exposed to low doses of ionizing radiations become refractory to high doses of radiation as well as to chemical mutagens that induce double-strand breaks in DNA.Q44748096
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Very low doses of X-rays can cause human lymphocytes to become less susceptible to ionizing radiationQ46563098
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Radiation-induced apoptosis in human tumor cell lines: adaptive response and split-dose effectQ47930017
Repeated exposure of human fibroblasts to ionizing radiation reveals an adaptive response that is not mediated by interleukin-6 or TGF-β.Q49052607
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Radio-adaptive response of base excision repair genes and proteins in human peripheral blood mononuclear cells exposed to gamma radiation.Q54163342
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Differential Response and Priming Dose Effect on the Proteome of Human Fibroblast and Stem Cells Induced by Exposure to Low Doses of Ionizing Radiation.Q38789663
Influence of Nucleoshuttling of the ATM Protein in the Healthy Tissues Response to Radiation Therapy: Toward a Molecular Classification of Human RadiosensitivityQ38794946
Role of AKT and ERK pathways in controlling sensitivity to ionizing radiation and adaptive response induced by low-dose radiation in human immune cellsQ38835964
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Individual response to ionizing radiationQ39029713
Role of DNA methylation in long-term low-dose γ-rays induced adaptive response in human B lymphoblast cells.Q39149195
Impact of dose-rate on the low-dose hyper-radiosensitivity and induced radioresistance (HRS/IRR) responseQ39158210
Hormesis: a fundamental concept in biologyQ39208027
Radiation-induced adaptive response is not seen in cell lines showing a bystander effect but is seen in lines showing HRS/IRR responseQ39885475
The nucleo-shuttling of the ATM protein as a basis for a novel theory of radiation response: resolution of the linear-quadratic modelQ39974933
DNA double-strand break repair defects in syndromes associated with acute radiation response: at least two different assays to predict intrinsic radiosensitivity?Q40017097
The Integration of LNT and Hormesis for Cancer Risk Assessment Optimizes Public Health ProtectionQ40063654
Enhancement of radiation-induced apoptosis by preirradiation with low-dose X-rays in human leukemia MOLT-4 cellsQ40526575
Dose responses for adaption to low doses of (60)Co gamma rays and (3)H beta particles in normal human fibroblastsQ40719986
Relationship between radiation-induced low-dose hypersensitivity and the bystander effectQ40736830
Adaptive response and its variation in human normal and tumour cellsQ40832189
Effects of low-dose (2 cGy) X-ray on cell-cycle kinetics and on induced mitotic delay in human lymphocyteQ40942536
Induction of an adaptive response against spontaneous neoplastic transformation in vitro by low-dose gamma radiationQ41042672
Hypersensitivity to very-low single radiation doses: its relationship to the adaptive response and induced radioresistanceQ41245939
Adaptive response to ionizing radiation induced by low doses of gamma rays in human cell lines.Q41277654
The elimination of low-dose hypersensitivity in Chinese hamster V79-379A cells by pretreatment with X rays or hydrogen peroxide.Q41372926
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P433issue3
P407language of work or nameEnglishQ1860
P921main subjecttoxicologyQ7218
P304page(s)1559325818789836
P577publication date2018-07-01
P1433published inDose-ResponseQ20181483
P1476titleInfluence of Individual Radiosensitivity on the Adaptive Response Phenomenon: Toward a Mechanistic Explanation Based on the Nucleo-Shuttling of ATM Protein
P478volume16

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cites work (P2860)
Q95269900Influence of Individual Radiosensitivity on the Hormesis Phenomenon: Toward a Mechanistic Explanation Based on the Nucleoshuttling of ATM Protein
Q64946635Repeated 0.2-Gy γ-Ray Irradiation Attenuates the Inflammatory Process and Endotoxin Damage Induced by Lipopolysaccharides.

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