Abnormal chemokine-induced responses of immature and mature hematopoietic cells from motheaten mice implicate the protein tyrosine phosphatase SHP-1 in chemokine responses

scientific article

Abnormal chemokine-induced responses of immature and mature hematopoietic cells from motheaten mice implicate the protein tyrosine phosphatase SHP-1 in chemokine responses is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1084/JEM.190.5.681
P932PMC publication ID2195618
P698PubMed publication ID10477552
P5875ResearchGate publication ID12821677

P50authorHal E. BroxmeyerQ51754776
P2093author name stringC H Kim
N Anzai
S Cooper
G Hangoc
G S Feng
C K Qu
P2860cites workRecruitment and activation of SHP-1 protein-tyrosine phosphatase by human platelet endothelial cell adhesion molecule-1 (PECAM-1). Identification of immunoreceptor tyrosine-based inhibitory motif-like binding motifs and substratesQ22003966
CD22 associates with protein tyrosine phosphatase 1C, Syk, and phospholipase C-gamma(1) upon B cell activationQ24310493
The chemokine monocyte chemotactic protein 1 triggers Janus kinase 2 activation and tyrosine phosphorylation of the CCR2B receptorQ24316405
A highly efficacious lymphocyte chemoattractant, stromal cell-derived factor 1 (SDF-1)Q24677007
Identification of the tyrosine phosphatase PTP1C as a B cell antigen receptor-associated protein involved in the regulation of B cell signalingQ24678964
Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signalsQ28236222
Human chemokines: an updateQ28237635
CK beta-11/macrophage inflammatory protein-3 beta/EBI1-ligand chemokine is an efficacious chemoattractant for T and B cellsQ28264381
Direct regulation of ZAP-70 by SHP-1 in T cell antigen receptor signalingQ28279660
Macrophage-inflammatory protein-3 beta/EBI1-ligand chemokine/CK beta-11, a CC chemokine, is a chemoattractant with a specificity for macrophage progenitors among myeloid progenitor cellsQ28281274
The chemokine receptor CXCR4 is essential for vascularization of the gastrointestinal tractQ28504884
Chemokines: signal lamps for trafficking of T and B cells for development and effector function.Q52035782
The major SHP-1-binding, tyrosine-phosphorylated protein in macrophages is a member of the KIR/LIR family and an SHP-1 substrate.Q52182161
Role of Rho in chemoattractant-activated leukocyte adhesion through integrinsQ70960218
Pharmacologic study of basophil histamine release induced by monocyte chemotactic protein-1 with kinase inhibitorsQ71388022
Receptors and transduction pathways for monocyte chemotactic protein-2 and monocyte chemotactic protein-3. Similarities and differences with MCP-1Q72332793
Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase geneQ72872607
SLC/exodus2/6Ckine/TCA4 induces chemotaxis of hematopoietic progenitor cells: differential activity of ligands of CCR7, CXCR3, or CXCR4 in chemotaxis vs. suppression of progenitor proliferationQ73017045
In vitro behavior of hematopoietic progenitor cells under the influence of chemoattractants: stromal cell-derived factor-1, steel factor, and the bone marrow environmentQ73981895
Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4Q77952550
Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar developmentQ28512895
Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1Q29616092
Chemokines--chemotactic cytokines that mediate inflammationQ29616433
ChemokinesQ29616435
Chemotactic peptide modulation of actin assembly and locomotion in neutrophilsQ30442376
Lack of SHPTP1 results in src-family kinase hyperactivation and thymocyte hyperresponsivenessQ30453894
Regulation of hematopoiesis in a sea of chemokine family members with a plethora of redundant activitiesQ33676765
Positive versus negative signaling by lymphocyte antigen receptorsQ34468852
"Viable motheaten," a new allele at the motheaten locus. I. PathologyQ35858405
Recruitment of SH2-containing protein tyrosine phosphatase SHP-1 to the interleukin 2 receptor; loss of SHP-1 expression in human T-lymphotropic virus type I-transformed T cellsQ36011208
The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood.Q36376700
A deletion mutation in the SH2-N domain of Shp-2 severely suppresses hematopoietic cell developmentQ36572223
Unresponsiveness of primitive chronic myeloid leukemia cells to macrophage inflammatory protein 1 alpha, an inhibitor of primitive normal hematopoietic cellsQ36739192
Hematopoietic cell phosphatase associates with the interleukin-3 (IL-3) receptor beta chain and down-regulates IL-3-induced tyrosine phosphorylation and mitogenesisQ36827728
Molecular mechanism of desensitization of the chemokine receptor CCR-5: receptor signaling and internalization are dissociable from its role as an HIV-1 co-receptorQ38878235
Modulation of integrin function in hematopoietic progenitor cells by CD43 engagement: possible involvement of protein tyrosine kinase and phospholipase C-gamma.Q40955738
Interleukin-8 receptors R1 and R2 activate mitogen-activated protein kinases and induce c-fos, independent of Ras and Raf-1 in Chinese hamster ovary cellsQ40990157
The B-cell transmembrane protein CD72 binds to and is an in vivo substrate of the protein tyrosine phosphatase SHP-1.Q41008340
The alpha-chemokine, stromal cell-derived factor-1alpha, binds to the transmembrane G-protein-coupled CXCR-4 receptor and activates multiple signal transduction pathwaysQ41012131
Human chemokines: enhancement of specific activity and effects in vitro on normal and leukemic progenitors and a factor-dependent cell line and in vivo in miceQ41279148
Severe defects in immunity and hematopoiesis caused by SHP-1 protein-tyrosine-phosphatase deficiencyQ41570741
Chemokines regulate cellular polarization and adhesion receptor redistribution during lymphocyte interaction with endothelium and extracellular matrix. Involvement of cAMP signaling pathwayQ41833771
Modulation of the neurotransmitter release in rat cerebellar neurons by GRO betaQ42465521
Expression and catalytic activity of the tyrosine phosphatase PTP1C is severely impaired in motheaten and viable motheaten miceQ42942030
Phosphorylation by a G protein-coupled kinase inhibits signaling and promotes internalization of the monocyte chemoattractant protein-1 receptor. Critical role of carboxyl-tail serines/threonines in receptor function.Q46096926
Regulation of B cell signal transduction by SH2-containing protein-tyrosine phosphatasesQ47722514
Negative regulation of antigen receptor signaling in lymphocytesQ47726720
Differential chemotactic behavior of developing T cells in response to thymic chemokinesQ48004884
Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) geneQ48111435
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)681-690
P577publication date1999-09-01
P1433published inJournal of Experimental MedicineQ3186912
P1476titleAbnormal chemokine-induced responses of immature and mature hematopoietic cells from motheaten mice implicate the protein tyrosine phosphatase SHP-1 in chemokine responses
P478volume190

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cites work (P2860)
Q35950048Aberrant regulation of hematopoiesis by T cells in BAZF-deficient mice
Q33903127Altered responsiveness to chemokines due to targeted disruption of SHIP.
Q28140552Beta-chemokine receptor CCR5 signals through SHP1, SHP2, and Syk
Q74336537Biological effects of stroma-derived factor-1 alpha on normal and CML CD34+ haemopoietic cells
Q39816788CD26 expression on T cell lines increases SDF-1-alpha-mediated invasion
Q33905233Central neuroinvasion and demyelination by inflammatory macrophages after peripheral virus infection is controlled by SHP-1.
Q41818218Commentary: IL-4 and IL-13 receptors and signaling
Q36036513Cyclin dependent kinase inhibitors differentially modulate synergistic cytokine responsiveness of hematopoietic progenitor cells
Q33898986Cytoplasmic protein tyrosine phosphatases SHP-1 and SHP-2: regulators of B cell signal transduction.
Q40678706Differential regulation of CXCR4-mediated T-cell chemotaxis and mitogen-activated protein kinase activation by the membrane tyrosine phosphatase, CD45.
Q30885800Effect of monocyte chemoattractant protein-1 on murine bone marrow cells: proliferation, colony-forming ability and signal transduction pathway involved
Q42063604FoxP3+ regulatory T cells restrain splenic extramedullary myelopoiesis via suppression of hemopoietic cytokine-producing T cells
Q34125272Hematopoietic factor erythropoietin fosters neuroprotection through novel signal transduction cascades
Q34234127Human immunodeficiency virus type-1 and chemokines: beyond competition for common cellular receptors
Q48770173Inhibition of protein tyrosine phosphatases enhances cerebral collateral growth in rats
Q37348839Interferon-beta treatment in multiple sclerosis attenuates inflammatory gene expression through inducible activity of the phosphatase SHP-1.
Q33441893Interplay between the heterotrimeric G-protein subunits Galphaq and Galphai2 sets the threshold for chemotaxis and TCR activation
Q36167584Intracellular signalling controlling integrin activation in lymphocytes
Q37301528Macrophages of multiple sclerosis patients display deficient SHP-1 expression and enhanced inflammatory phenotype
Q37367608Mechanism of eosinophilic esophagitis
Q36806357Modulation of Hematopoietic Chemokine Effects In Vitro and In Vivo by DPP-4/CD26.
Q85409525Neutrophil infiltration during inflammation is regulated by PILRα via modulation of integrin activation
Q24535532Novel mesenchymal and haematopoietic cell isoforms of the SHP-2 docking receptor, PZR: identification, molecular cloning and effects on cell migration
Q59133604Protein Tyrosine Phosphatases: Regulators of CD4 T Cells in Inflammatory Bowel Disease
Q34352091Regulation of hematopoiesis by chemokine family members
Q37847669Regulation of tyrosine phosphorylation in macrophage phagocytosis and chemotaxis
Q43824396Requirement for CD28 co-stimulation is lower in SHP-1-deficient T cells
Q28216204SHP1 protein-tyrosine phosphatase regulates HoxA10 DNA binding and transcriptional repression activity in undifferentiated myeloid cells
Q24290736SHP2 and cbl participate in alpha-chemokine receptor CXCR4-mediated signaling pathways
Q41949111STAT3-dependent IL-21 production from T helper cells regulates hematopoietic progenitor cell homeostasis
Q24297942Shp-1 mediates the antiproliferative activity of tissue inhibitor of metalloproteinase-2 in human microvascular endothelial cells
Q36973659Shp1 regulates T cell homeostasis by limiting IL-4 signals
Q33851655Shp1 signalling is required to establish the long-lived bone marrow plasma cell pool
Q35085522Signal transduction events regulating integrin function and T cell migration: new functions and complexity
Q30424937Src homology domain 2-containing protein-tyrosine phosphatase-1 (SHP-1) binds and dephosphorylates G(alpha)-interacting, vesicle-associated protein (GIV)/Girdin and attenuates the GIV-phosphatidylinositol 3-kinase (PI3K)-Akt signaling pathway
Q36806897Stromal cell derived factor-1 alpha confers protection against myocardial ischemia/reperfusion injury: role of the cardiac stromal cell derived factor-1 alpha CXCR4 axis
Q74471802Th1 cells regulate hematopoietic progenitor cell homeostasis by production of oncostatin M
Q36836455The Src homology 2 domain tyrosine phosphatases SHP-1 and SHP-2: diversified control of cell growth, inflammation, and injury

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