Sarcolipin is a novel regulator of muscle metabolism and obesity

scientific article

Sarcolipin is a novel regulator of muscle metabolism and obesity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.PHRS.2015.10.020
P932PMC publication ID4684434
P698PubMed publication ID26521759
P5875ResearchGate publication ID283456559

P2093author name stringMuthu Periasamy
Santosh Kumar Maurya
P2860cites workMalignant hyperthermiaQ21203008
Characterization of the gene encoding human sarcolipin (SLN), a proteolipid associated with SERCA1: absence of structural mutations in five patients with Brody diseaseQ24336206
Sarcolipin uncouples hydrolysis of ATP from accumulation of Ca2+ by the Ca2+-ATPase of skeletal-muscle sarcoplasmic reticulumQ24533577
Identification and importance of brown adipose tissue in adult humansQ24632425
Exercise induces transient transcriptional activation of the PGC-1alpha gene in human skeletal muscleQ24657207
Ablation of sarcolipin enhances sarcoplasmic reticulum calcium transport and atrial contractilityQ24679092
Crystal structures of the calcium pump and sarcolipin in the Mg2+-bound E1 stateQ27684107
The sarcolipin-bound calcium pump stabilizes calcium sites exposed to the cytoplasmQ27684110
Brown and Beige Fat: Molecular Parts of a Thermogenic MachineQ28082723
A role for brown adipose tissue in diet-induced thermogenesisQ28253495
Mice lacking mitochondrial uncoupling protein are cold-sensitive but not obeseQ28510931
UCP1 ablation induces obesity and abolishes diet-induced thermogenesis in mice exempt from thermal stress by living at thermoneutralityQ28513102
Mitochondrial ATP synthase F1-beta-subunit is a calcium-binding proteinQ28578088
The role of skeletal-muscle-based thermogenic mechanisms in vertebrate endothermyQ28603354
Brown adipose tissue: function and physiological significanceQ29547448
Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibresQ29555845
Beige adipocytes are a distinct type of thermogenic fat cell in mouse and humanQ29617382
Phospholamban: protein structure, mechanism of action, and role in cardiac functionQ30431816
The structure of the membrane systems in a novel muscle cell modified for heat productionQ30494572
Sarcolipin is a newly identified regulator of muscle-based thermogenesis in mammals.Q30540446
Uncoupling protein--a useful energy dissipatorQ33827384
Towards a molecular understanding of adaptive thermogenesisQ33892351
SERCA pump isoforms: their role in calcium transport and diseaseQ34002326
SERCA pump level is a critical determinant of Ca(2+)homeostasis and cardiac contractilityQ34083460
Mitochondrial uncoupling proteins: from mitochondria to the regulation of energy balanceQ34083602
Skeletal muscle metabolism is a major determinant of resting energy expenditureQ34262816
Brown adipose tissue regulates glucose homeostasis and insulin sensitivity.Q34316238
Adaptive thermogenesis in adipocytes: is beige the new brown?Q34326605
Increased sarcolipin expression and decreased sarco(endo)plasmic reticulum Ca2+ uptake in skeletal muscles of mouse models of Duchenne muscular dystrophyQ44826878
Cold tolerance in hypothyroid rabbits: role of skeletal muscle mitochondria and sarcoplasmic reticulum Ca2+ ATPase isoform 1 heat production.Q46429156
Role of calcineurin in exercise-induced mitochondrial biogenesisQ46887677
Size analysis of uncoupling protein and its precursor from brown adipose tissue of different speciesQ47220556
Effects of Ca2+ on oxidative phosphorylation in mitochondria from the thermogenic organ of marlin.Q50533412
The presence of sarcolipin results in increased heat production by Ca(2+)-ATPase.Q51932184
The effect of environmental conditions on the growth and function of brown adipose tissueQ52999992
Differential metabolism of brown adipose tissue in newborn rabbits in relation to position in the litter huddle.Q53510667
Heat from calcium cycling melts fatQ56171566
Effects of palmitoyl carnitine and related metabolites on the avian Ca(2+)-ATPase and Ca2+ release channelQ57200997
Increased proton conductance pathway in brown adipose tissue mitochondria of rats exhibiting diet-induced thermogenesisQ59060396
Calcineurin and calcium/calmodulin-dependent protein kinase activate distinct metabolic gene regulatory programs in cardiac muscleQ64379442
Contribution of skeletal muscle to nonshivering thermogenesis in the dogQ68724348
Epinephrine mediates facultative carbohydrate-induced thermogenesis in human skeletal muscleQ69733487
Effects of dietary essential fatty acids on active thermogenin content in rat brown adipose tissueQ70159426
Expression of sarcoplasmic reticulum Ca2+ transport proteins in cold-acclimating ducklingsQ71552938
Effect of sucrose overfeeding on brown adipose tissue lipogenesis and lipoprotein lipase activity in ratsQ71670594
Sarcoplasmic reticulum Ca(2+)-ATPase and ryanodine receptor in cold-acclimated ducklings and thermogenesisQ72030538
Potential for Non-shivering Thermogenesis in Perfused Chicken (Gallus domesticus) MuscleQ73502337
Calcium activation of mitochondrial glycerol phosphate dehydrogenase restudiedQ34373156
Life without UCP1: mitochondrial, cellular and organismal characteristics of the UCP1-ablated mice.Q34439567
Mitochondrial matrix phosphoproteome: effect of extra mitochondrial calciumQ34483436
Thermogenic activity of Ca2+-ATPase from skeletal muscle heavy sarcoplasmic reticulum: the role of ryanodine Ca2+ channelQ34623786
ATP consumption by sarcoplasmic reticulum Ca²⁺ pumps accounts for 40-50% of resting metabolic rate in mouse fast and slow twitch skeletal muscle.Q34809270
Structure-function relationships in Ca(2+) cycling proteinsQ34863496
Phospholamban: a crucial regulator of cardiac contractilityQ35167969
Sarcolipin overexpression improves muscle energetics and reduces fatigueQ35437635
Sarcolipin Is a Key Determinant of the Basal Metabolic Rate, and Its Overexpression Enhances Energy Expenditure and Resistance against Diet-induced Obesity.Q35536274
Uncoupling Protein 1 and Sarcolipin Are Required to Maintain Optimal Thermogenesis, and Loss of Both Systems Compromises Survival of Mice under Cold StressQ35583165
The N Terminus of Sarcolipin Plays an Important Role in Uncoupling Sarco-endoplasmic Reticulum Ca2+-ATPase (SERCA) ATP Hydrolysis from Ca2+ TransportQ35662355
Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans.Q35698990
Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytesQ35780260
Phospholamban overexpression in mice causes a centronuclear myopathy-like phenotype.Q35923504
Characterization of the sarcoplasmic reticulum proteins in the thermogenic muscles of fishQ36234886
Role of PKCδ in Insulin Sensitivity and Skeletal Muscle MetabolismQ36311581
Sarcolipin protein interaction with sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA) is distinct from phospholamban protein, and only sarcolipin can promote uncoupling of the SERCA pump.Q36666112
Regulation of mitochondrial ATP synthesis by calcium: evidence for a long-term metabolic primingQ36702104
Sarco(endo)plasmic reticulum calcium ATPase (SERCA) inhibition by sarcolipin is encoded in its luminal tailQ36708601
Sarcolipin trumps β-adrenergic receptor signaling as the favored mechanism for muscle-based diet-induced thermogenesis.Q37118731
Differential expression of sarcolipin protein during muscle development and cardiac pathophysiologyQ37252432
Lipidomics analysis revealed the phospholipid compositional changes in muscle by chronic exercise and high-fat dietQ37326773
Skeletal muscle mitochondrial uncoupling, adaptive thermogenesis and energy expenditure.Q37854354
The role of in vivo Ca²⁺ signals acting on Ca²⁺-calmodulin-dependent proteins for skeletal muscle plasticityQ37930824
The role of mitochondrial Ca2+ transport and matrix Ca2+ in signal transduction in mammalian tissuesQ37950387
Regulation of ATP production by mitochondrial Ca(2+).Q38002541
Sarcolipin provides a novel muscle-based mechanism for adaptive thermogenesis.Q38221904
The disorders of the calcium release unit of skeletal muscles: what have we learned from mouse models?Q38271367
Increase in cytochrome oxidase capacity of BAT and other tissues in cold-acclimated gerbilsQ38917594
Thermogenesis in muscleQ40660704
Persistence of diet-induced obesity despite access to voluntary activity in mice lacking sarcolipinQ41849223
Integrating cytosolic calcium signals into mitochondrial metabolic responsesQ42652819
Ca2+ -dependent interaction of S100A1 with F1-ATPase leads to an increased ATP content in cardiomyocytesQ42738033
Hyperthyroidism increases the uncoupled ATPase activity and heat production by the sarcoplasmic reticulum Ca2+-ATPaseQ43003203
Purification and properties of an adenosine triphosphatase from sarcoplasmic reticulum.Q43558757
Ablation of sarcolipin decreases the energy requirements for Ca2+ transport by sarco(endo)plasmic reticulum Ca2+-ATPases in resting skeletal muscleQ44123306
Thermogenic response to epinephrine in the forearm and abdominal subcutaneous adipose tissueQ44186927
Characterization of ryanodine receptor and Ca2+-ATPase isoforms in the thermogenic heater organ of blue marlin (Makaira nigricans).Q44291279
P304page(s)270-275
P577publication date2015-10-30
P1433published inPharmacological ResearchQ15724622
P1476titleSarcolipin is a novel regulator of muscle metabolism and obesity
P478volume102

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cites work (P2860)
Q41045820Increased Reliance on Muscle-based Thermogenesis upon Acute Minimization of Brown Adipose Tissue Function
Q58616127Regulator of Calcineurin 1 helps coordinate whole-body metabolism and thermogenesis
Q38713977Role of SERCA Pump in Muscle Thermogenesis and Metabolism
Q37047984Sarcolipin and uncoupling protein 1 play distinct roles in diet-induced thermogenesis and do not compensate for one another
Q42804825Skeletal Muscle Thermogenesis and Its Role in Whole Body Energy Metabolism
Q90280408Skeletal muscle thermogenesis induction by exposure to predator odor
Q94550867Skeletal-Muscle Metabolic Reprogramming in ALS-SOD1G93A Mice Predates Disease Onset and Is A Promising Therapeutic Target
Q57491001The Role of Sarcolipin in Muscle Non-shivering Thermogenesis