| scholarly article | Q13442814 |
| P356 | DOI | 10.1007/S00702-005-0415-0 |
| P698 | PubMed publication ID | 16463115 |
| P2093 | author name string | T Obata | |
| P2860 | cites work | Strong Inhibition of Neuronal Nitric Oxide Synthase by the Calmodulin Antagonist and Anti-Estrogen Drug Tamoxifen | Q74178114 |
| The parkinsonism-inducing drug 1-methyl-4-phenylpyridinium triggers intracellular dopamine oxidation. A novel mechanism of toxicity | Q74254040 | ||
| Blockade by NS-7, a neuroprotective compound, of both L-type and P/Q-type Ca2+ channels involving depolarization-stimulated nitric oxide synthase activity in primary neuronal culture | Q74484859 | ||
| Hydroxyl radicals and nitric oxide in neurotoxicity and neuroprotection | Q77093965 | ||
| Exercise improves flow-mediated vasodilatation of skeletal muscle arteries in rats with chronic heart failure. Role of nitric oxide, prostanoids, and oxidant stress | Q77846360 | ||
| Methamphetamine‐Induced Rapid and Reversible Reduction in the Activities of Tryptophan Hydroxylase and Dopamine Transporters: Oxidative Consequences?a | Q95806919 | ||
| Nitric oxide synthase in cardiac sarcoplasmic reticulum | Q22008689 | ||
| Prospects for new restorative and neuroprotective treatments in Parkinson's disease | Q28138668 | ||
| 1-Methyl-4-phenylpyridinium ion (MPP+): Identification of a metabolite of MPTP, a toxin selective to the substantia nigra | Q28266104 | ||
| Vascular endothelial cells synthesize nitric oxide from L-arginine | Q28291036 | ||
| Amphetamine redistributes dopamine from synaptic vesicles to the cytosol and promotes reverse transport | Q28301517 | ||
| Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine | Q28510205 | ||
| VMAT2 knockout mice: Heterozygotes display reduced amphetamine-conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity | Q28512294 | ||
| Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide | Q29547245 | ||
| Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and ugly | Q29547442 | ||
| Mitochondrial toxins in models of neurodegenerative diseases. I: in vivo brain hydroxyl radical production during sytemic MPTP treatment or following microdialysis infusion of methylpyridinium or azide ions | Q30471061 | ||
| Selective estrogen receptor modulators: structure, function, and clinical use. | Q30912456 | ||
| Methamphetamine-induced rapid and reversible changes in dopamine transporter function: an in vitro model. | Q31840658 | ||
| Nitric oxide, mitochondria and neurological disease | Q33540925 | ||
| Molecular biology of catecholamine-related enzymes in relation to Parkinson's disease. | Q33541804 | ||
| Etiology and pathogenesis of Parkinson's disease | Q33593402 | ||
| Dopamine turnover and glutathione oxidation: implications for Parkinson disease | Q33838901 | ||
| Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease | Q33951094 | ||
| Sensitive assay of hydroxyl free radical formation utilizing high pressure liquid chromatography with electrochemical detection of phenol and salicylate hydroxylation products. | Q64989287 | ||
| Histochemical detection of apoptosis in Parkinson's disease. | Q67401850 | ||
| In vivo trapping of hydroxyl free radicals in the striatum utilizing intracranial microdialysis perfusion of salicylate: effects of MPTP, MPDP+, and MPP+ | Q67505470 | ||
| Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxide | Q67509483 | ||
| Kinetics of superoxide dismutase- and iron-catalyzed nitration of phenolics by peroxynitrite | Q67568058 | ||
| Neurotoxic damage to the nigrostriatal system in rats following intranigral administration of MPDP+ and MPP+ | Q68103579 | ||
| Peroxynitrite-induced membrane lipid peroxidation: the cytotoxic potential of superoxide and nitric oxide | Q68255434 | ||
| Oxygen free radical involvement in ischemia and reperfusion injury to brain | Q68397183 | ||
| Use of salicylate as a probe for .OH formation in isolated ischemic rat hearts | Q68483453 | ||
| Acute effects of 1-methyl-4-phenylpyridinium ion (MPP+) on dopamine and serotonin metabolism in rat striatum as assayed in vivo by a micro-dialysis technique | Q68833144 | ||
| The effect of melanin on iron associated decomposition of hydrogen peroxide | Q69824491 | ||
| MPTP neurotoxicity: an overview and characterization of phases of toxicity | Q69856142 | ||
| A brainstem atlas of catecholaminergic neurons in man, using melanin as a natural marker | Q70765260 | ||
| S-nitrosothiols and nitric oxide, but not sodium nitroprusside, protect nigrostriatal dopamine neurons against iron-induced oxidative stress in vivo | Q71301105 | ||
| Enzyme-independent formation of nitric oxide in biological tissues | Q71803601 | ||
| ESR spin trapping investigation on peroxynitrite decomposition: no evidence for hydroxyl radical production | Q72767138 | ||
| S-Methylthiocitrulline, a neuronal nitric oxide synthase inhibitor, protects against malonate and MPTP neurotoxicity | Q73123595 | ||
| Systemic administration of D-amphetamine induced a delayed production of nitric oxide in the striatum of rats | Q73305369 | ||
| Rapid and differential losses of in vivo dopamine transporter (DAT) and vesicular monoamine transporter (VMAT2) radioligand binding in MPTP-treated mice | Q73405622 | ||
| Implication of poly (ADP-ribose) polymerase (PARP) in neurodegeneration and brain energy metabolism. Decreases in mouse brain NAD+ and ATP caused by MPTP are prevented by the PARP inhibitor benzamide | Q73432707 | ||
| Estrogen modulates responses of striatal dopamine neurons to MPP(+): evaluations using in vitro and in vivo techniques | Q74105958 | ||
| Neurochemical findings in the MPTP model of Parkinson's disease | Q33956644 | ||
| Structure and function of the dopamine transporter | Q34061069 | ||
| Formation of nitric oxide from L-arginine in the central nervous system: a transduction mechanism for stimulation of the soluble guanylate cyclase | Q34288133 | ||
| In vivo generation of hydroxyl radicals and MPTP-induced dopaminergic toxicity in the basal ganglia. | Q34316878 | ||
| The role of mitochondrial dysfunction and neuronal nitric oxide in animal models of neurodegenerative diseases | Q34440280 | ||
| Oxidative mechanisms in nigral cell death in Parkinson's disease | Q34470447 | ||
| Nitric oxide and depolarization induce hydroxyl radical generation | Q34538969 | ||
| Environmental estrogen-like chemicals and hydroxyl radicals induced by MPTP in the striatum: a review | Q34685497 | ||
| Dopamine efflux by MPTP and hydroxyl radical generation | Q34803663 | ||
| Apoptosis inducing factor and PARP-mediated injury in the MPTP mouse model of Parkinson's disease | Q35171012 | ||
| Possible mechanism for the neuroprotective effects of L-carnitine on methamphetamine-evoked neurotoxicity | Q35174574 | ||
| Evidence of neuronal oxidative damage in Alzheimer's disease. | Q35782389 | ||
| Malfunction of vascular control in lifestyle-related diseases: formation of systemic hemoglobin-nitric oxide complex (HbNO) from dietary nitrite | Q35984010 | ||
| Peroxynitrite and drug-dependent toxicity | Q36029992 | ||
| Parkinson's disease: pathophysiology | Q36495393 | ||
| Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity | Q37597604 | ||
| Prostaglandins and the release of the adrenergic transmitter | Q37601819 | ||
| Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity | Q37683630 | ||
| MPTP toxicity: implications for research in Parkinson's disease | Q39602394 | ||
| Altered brain metabolism of iron as a cause of neurodegenerative diseases? | Q40391355 | ||
| Nitric oxide and oxygen radicals: a question of balance | Q40467964 | ||
| Methamphetamine- and 1-methyl-4-phenyl- 1,2,3, 6-tetrahydropyridine-induced dopaminergic neurotoxicity in inducible nitric oxide synthase-deficient mice | Q40631249 | ||
| Peroxynitrite inactivates the human dopamine transporter by modification of cysteine 342: potential mechanism of neurotoxicity in dopamine neurons. | Q40728188 | ||
| Molecular physiology and regulation of catecholamine transporters. | Q41084438 | ||
| MPP+-induced efflux of dopamine and lactate from rat striatum have similar time courses as shown by in vivo brain dialysis | Q41253077 | ||
| Catecholamine toxicity: a proposal for the molecular pathogenesis of manganese neurotoxicity and Parkinson's disease | Q41582319 | ||
| The dopamine transporter: a crucial component regulating dopamine transmission. | Q41649915 | ||
| Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice. | Q41664189 | ||
| The role of nitric oxide in neurodegeneration. Potential for pharmacological intervention | Q41757009 | ||
| The apparent autoxidation rate of catechols in dopamine-rich regions of human brains increases with the degree of depigmentation of substantia nigra | Q42192455 | ||
| Involvement of oxygen-based radicals in methamphetamine-induced neurotoxicity: evidence from the use of CuZnSOD transgenic mice | Q42275524 | ||
| Differential effects of chronic antipsychotic drug treatment on extracellular glutamate and dopamine concentrations. | Q42491361 | ||
| Role of nitric oxide in methamphetamine neurotoxicity: protection by 7-nitroindazole, an inhibitor of neuronal nitric oxide synthase | Q42552381 | ||
| Interactions of the neurotoxic amine 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine with monoamine oxidases | Q42853435 | ||
| Tamoxifen inhibits nitrotyrosine formation after reversible middle cerebral artery occlusion in the rat. | Q43548224 | ||
| Nitric oxide enhances MPP(+)-induced hydroxyl radical generation via depolarization activated nitric oxide synthase in rat striatum | Q43625070 | ||
| Release of dopamine by perfusion with 1-methyl-4-phenylpyridinium ion (MPP(+)) into the striatum is associated with hydroxyl free radical generation | Q43656849 | ||
| Protective effect of tamoxifen on 1-methyl-4-phenylpyridine-induced hydroxyl radical generation in the rat striatum | Q43678396 | ||
| Impairment of the neuronal dopamine transporter activity in MPP+-treated rat was not prevented by treatments with nitric oxide synthase or poly(ADP-ribose) polymerase inhibitors | Q43792009 | ||
| [123I]beta-CIT SPECT imaging assessment of the rate of Parkinson's disease progression | Q43820139 | ||
| [(123)I]beta-CIT SPECT imaging demonstrates reduced density of striatal dopamine transporters in Parkinson's disease and multiple system atrophy | Q43827115 | ||
| Hydroxylation of salicylate as an assay for hydroxyl radicals: a cautionary note | Q43841243 | ||
| Calcium overload enhances hydroxyl radical generation by 1-methyl-4 phenylpyridinium ion (MPP+) in rat striatum | Q44318956 | ||
| Protection against MPP+ neurotoxicity in cerebellar granule cells by antioxidants | Q44933179 | ||
| Inhibition of Monoamine Oxidase Contributes to the Protective Effect of 7‐Nitroindazole Against MPTP Neurotoxicity | Q46128651 | ||
| In vivo autoxidation of dopamine in guinea pig striatum increases with age. | Q46855135 | ||
| Long-lasting effects of chronic neonatal blockade of N-methyl-D-aspartate receptor through the competitive antagonist CGP 39551 in rats. | Q48135592 | ||
| Neuronal nitric oxide synthase inhibition reduces MPP+-evoked hydroxyl radical formation but not dopamine efflux in rat striatum | Q48139365 | ||
| Methamphetamine neurotoxicity involves vacuolation of endocytic organelles and dopamine-dependent intracellular oxidative stress. | Q48144142 | ||
| Reserpine prevents hydroxyl radical formation by MPP+ in rat striatum | Q48215384 | ||
| Analysis of the neuroprotective effects of various nitric oxide donor compounds in murine mixed cortical cell culture | Q48227550 | ||
| Increased nitrotyrosine immunoreactivity in substantia nigra neurons in MPTP treated baboons is blocked by inhibition of neuronal nitric oxide synthase | Q48253577 | ||
| Enhancement by tamoxifen of the membrane antioxidant action of the yeast membrane sterol ergosterol: relevance to the antiyeast and anticancer action of tamoxifen | Q48265863 | ||
| Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures | Q48281625 | ||
| Role of dopamine autoxidation, hydroxyl radical generation, and calcium overload in underlying mechanisms involved in MPTP-induced parkinsonism. | Q48370517 | ||
| Neurochemical and Neurogenetic Correlates of Parkinson's Disease | Q48403913 | ||
| Neuroprotection by nitric oxide against hydroxyl radical-induced nigral neurotoxicity | Q48411565 | ||
| Mechanisms of MPTP toxicity | Q48456918 | ||
| Protein Nitration in Parkinsonʼs Disease | Q48463667 | ||
| The structural mimicry of membrane sterols by tamoxifen: evidence from cholesterol coefficients and molecular-modelling for its action as a membrane anti-oxidant and an anti-cancer agent | Q48507190 | ||
| Inhibition of Depolarization‐Induced Nitric Oxide Synthase Activation by NS‐7, a Phenylpyrimidine Derivative, in Primary Neuronal Culture | Q48568898 | ||
| Uptake of MPP(+) by dopamine neurons explains selectivity of parkinsonism-inducing neurotoxin, MPTP. | Q48601969 | ||
| Oxygen radicals diminish dopamine transporter function in rat striatum | Q48606420 | ||
| Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism | Q48614154 | ||
| Iron-melanin interaction and lipid peroxidation: implications for Parkinson's disease | Q48627543 | ||
| Dopamine transporter is required for in vivo MPTP neurotoxicity: evidence from mice lacking the transporter. | Q48631699 | ||
| Severe depletion of cocaine recognition sites associated with the dopamine transporter in Parkinson's-diseased striatum | Q48663473 | ||
| [11C]RTI-32 PET studies of the dopamine transporter in early dopa-naive Parkinson's disease: implications for the symptomatic threshold | Q48695927 | ||
| Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons | Q48937244 | ||
| Estrogen protects primary cortical neurons from glutamate toxicity | Q48966197 | ||
| Myocardial protection by R 56865: a new principle based on prevention of ion channel pathology | Q51702780 | ||
| Effects of MPP+ on the release of serotonin and 5-hydroxyindoleacetic acid from rat striatum in vivo | Q51751119 | ||
| 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine metabolism and 1-methyl-4-phenylpyridinium uptake in dissociated cell cultures from the embryonic mesencephalon | Q51771662 | ||
| Suppression of hydroxyl radical formation by MAO inhibitors: a novel possible neuroprotective mechanism in dopaminergic neurotoxicity. | Q52030547 | ||
| Determination of hydroxylated aromatic compounds produced via superoxide-dependent formation of hydroxyl radicals by liquid chromatography/electrochemistry | Q53856944 | ||
| Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o'-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease | Q54071317 | ||
| Methamphetamine neurotoxicity: necrotic and apoptotic mechanisms and relevance to human abuse and treatment | Q57204867 | ||
| Aorta and Skeletal Muscle NO Synthase Expression in Experimental Heart Failure | Q57312535 | ||
| Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian Brains | Q61714001 | ||
| Potassium chloride depolarization enhances MPP+-induced hydroxyl radical generation in the rat striatum | Q64789872 | ||
| P433 | issue | 9 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 1131-1144 | |
| P577 | publication date | 2006-02-06 | |
| P13046 | publication type of scholarly work | review article | Q7318358 |
| P1433 | published in | Journal of Neural Transmission | Q15750921 |
| P1476 | title | Nitric oxide and MPP+-induced hydroxyl radical generation | |
| P478 | volume | 113 |
| Q60048374 | 3-(Naphthalen-2-yl(propoxy)methyl)azetidine hydrochloride attenuates MPP＋-induced cytotoxicity by regulating oxidative stress and mitochondrial dysfunction in SH-SY5Y cells |
| Q42711317 | Biochemical evaluation of the neurotoxicity of MPTP and MPP<sup>+</sup> in embryonic and newborn mice |
| Q48619319 | Different mechanisms of hydroxyl radical production susceptible to purine P2 receptor antagonists between carbon monoxide poisoning and exogenous ATP in rat striatum |
| Q38785295 | Hericium erinaceus mycelium and its isolated erinacine A protection from MPTP-induced neurotoxicity through the ER stress, triggering an apoptosis cascade |
| Q37735813 | In vivo microdialysis in Parkinson's research. |
| Q39201271 | Induction of KLF4 contributes to the neurotoxicity of MPP + in M17 cells: a new implication in Parkinson's disease |
| Q48690646 | Involvement of monoamine oxidase-B in the acute neurotoxicity of MPTP in embryonic and newborn mice |
| Q37668187 | MPP+ induces necrostatin-1- and ferrostatin-1-sensitive necrotic death of neuronal SH-SY5Y cells |
| Q34606186 | Molecular mechanisms of excitotoxicity and their relevance to pathogenesis of neurodegenerative diseases |
| Q81319000 | Neurobehavioral protection by single dose l-deprenyl against MPTP-induced parkinsonism in common marmosets |
| Q28482356 | Neuroprotective activities of palmitoylethanolamide in an animal model of Parkinson's disease |
| Q92154139 | Novel neuroprotective hydroquinones with a vinyl alkyne from the fungus, Pestalotiopsis microspora |
| Q40220627 | Obligatory role for complex I inhibition in the dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). |
| Q36162933 | Quercetin and sesamin protect dopaminergic cells from MPP+-induced neuroinflammation in a microglial (N9)-neuronal (PC12) coculture system |
| Q37273506 | Sesamin modulates tyrosine hydroxylase, superoxide dismutase, catalase, inducible NO synthase and interleukin-6 expression in dopaminergic cells under MPP+-induced oxidative stress |
| Q35119950 | The parkinsonian mimetic, MPP+, specifically impairs mitochondrial transport in dopamine axons |
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