Beneficial Effects of Statins on the Rates of Hepatic Fibrosis, Hepatic Decompensation, and Mortality in Chronic Liver Disease: A Systematic Review and Meta-Analysis

scientific article

Beneficial Effects of Statins on the Rates of Hepatic Fibrosis, Hepatic Decompensation, and Mortality in Chronic Liver Disease: A Systematic Review and Meta-Analysis is …
instance of (P31):
meta-analysisQ815382
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1038/AJG.2017.170
P698PubMed publication ID28585556

P50authorChristopher D StaveQ56234820
George CholankerilQ59749426
Colin W HowdenQ87752670
Sanjaya K SatapathyQ88155709
Satheesh NairQ88834367
Faisal KamalQ89635985
Aijaz AhmedQ47168895
P2093author name stringMuhammad Ali Khan
Sehrish Kamal
Ankur Seth
Utkarsh Singh
Deepansh Gupta
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Lovastatin-mediated G1 arrest is through inhibition of the proteasome, independent of hydroxymethyl glutaryl-CoA reductaseQ24645348
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Simvastatin treatment improves liver sinusoidal endothelial dysfunction in CCl4 cirrhotic ratsQ59123185
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Three months of simvastatin therapy vs. placebo for severe portal hypertension in cirrhosis: A randomized controlled trialQ86035302
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Rho-dependent inhibition of the induction of connective tissue growth factor (CTGF) by HMG CoA reductase inhibitors (statins)Q28345499
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Hepatitis C virus RNA replication is regulated by host geranylgeranylation and fatty acidsQ29620653
Statins in liver disease: a molehill, an iceberg, or neither?Q30446668
Statins in the treatment of dyslipidemia in the presence of elevated liver aminotransferase levels: a therapeutic dilemmaQ33765060
Clinical outcomes of compensated and decompensated cirrhosis: A long term studyQ33948229
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Statin use in patients with cirrhosis: a retrospective cohort studyQ34661975
Statin use is associated with a reduced risk of fibrosis progression in chronic hepatitis CQ34747195
Vascular pathobiology in chronic liver disease and cirrhosis - current status and future directionsQ35136411
Hepatotoxicity of hypolipidemic drugsQ35184569
KLF2 Is a novel transcriptional regulator of endothelial proinflammatory activationQ36399199
Statins Are Associated With a Decreased Risk of Decompensation and Death in Veterans With Hepatitis C-Related Compensated Cirrhosis.Q36505496
Non-alcoholic fatty liver disease (NAFLD) and cardiovascular disease: an open question.Q36845502
Atorvastatin and fluvastatin are associated with dose-dependent reductions in cirrhosis and hepatocellular carcinoma, among patients with hepatitis C virus: Results from ERCHIVES.Q37029796
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Statins are associated with a reduced risk of hepatocellular cancer: a systematic review and meta-analysisQ38051955
Statins Reduce the Risk of Cirrhosis and Its Decompensation in Chronic Hepatitis B Patients: A Nationwide Cohort StudyQ38831540
Addition of Simvastatin to Standard Therapy for the Prevention of Variceal Rebleeding Does Not Reduce Rebleeding but Increases Survival in Patients With CirrhosisQ40100867
Statin drugs decrease progression to cirrhosis in HIV/hepatitis C virus coinfected individualsQ40501796
Statin drugs decrease progression to cirrhosis in HIV/HCV co-infected individualsQ40588764
Statin and the risk of hepatocellular carcinoma and death in a hospital-based hepatitis B-infected population: A propensity score landmark analysis.Q40699088
Statin use and the risk of cirrhosis development in patients with hepatitis C virus infectionQ40713539
Effect of addition of statins to antiviral therapy in hepatitis C virus-infected persons: Results from ERCHIVES.Q41109284
Statins potentiate the in vitro anti-hepatitis C virus activity of selective hepatitis C virus inhibitors and delay or prevent resistance developmentQ42168234
Blocking the Raf/MEK/ERK pathway sensitizes acute myelogenous leukemia cells to lovastatin-induced apoptosisQ42467738
Hepatotoxicity fears contribute to underutilization of statin medications by primary care physiciansQ43001285
Statin Therapy Improves Sustained Virologic Response Among Diabetic Patients With Chronic Hepatitis CQ43991768
Effects and regulation of connective tissue growth factor on hepatic stellate cells.Q44028827
Simvastatin enhances hepatic nitric oxide production and decreases the hepatic vascular tone in patients with cirrhosis.Q44779682
Hepatic effects of lovastatin exposure in patients with liver disease: a retrospective cohort studyQ45811781
Simvastatin lowers portal pressure in patients with cirrhosis and portal hypertension: a randomized controlled trialQ46126097
The transcription factor KLF2 mediates hepatic endothelial protection and paracrine endothelial-stellate cell deactivation induced by statinsQ46188566
Kruppel-like factor 2 as a novel mediator of statin effects in endothelial cellsQ46618533
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectsystematic reviewQ1504425
chronic liver diseaseQ5113984
decompensated cirrhosisQ109887496
P304page(s)1495-1505
P577publication date2017-06-06
P1433published inThe American Journal of GastroenterologyQ7713501
P1476titleBeneficial Effects of Statins on the Rates of Hepatic Fibrosis, Hepatic Decompensation, and Mortality in Chronic Liver Disease: A Systematic Review and Meta-Analysis
P478volume112

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