The activation status of neuroantigen-specific T cells in the target organ determines the clinical outcome of autoimmune encephalomyelitis (scientific article published in January 2004)

Single cell analysis reveals regulated hierarchical T cell antigen receptor signaling thresholds and intraclonal heterogeneity for individual cytokine responses of CD4+ T cells

Q28755947

Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis

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Improved retroviral vectors for gene transfer and expression

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In situ hybridization analysis of glial fibrillary acidic protein mRNA reveals evidence of biphasic astrocyte activation during acute experimental autoimmune encephalomyelitis

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Innate and adaptive immune responses can be beneficial for CNS repair

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Mechanisms of inflammation in MS tissue: adhesion molecules and chemokines

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Regulation of T-cell responses by CNS antigen-presenting cells: different roles for microglia and astrocytes

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Butyrophilin, a milk protein, modulates the encephalitogenic T cell response to myelin oligodendrocyte glycoprotein in experimental autoimmune encephalomyelitis.

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Antigen challenge leads to in vivo activation and elimination of highly polarized TH1 memory T cells

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T- and B-cell responses to myelin oligodendrocyte glycoprotein in experimental autoimmune encephalomyelitis and multiple sclerosis

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Prevention and treatment of experimental autoimmune encephalomyelitis by CNI-1493, a macrophage-deactivating agent.

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Thymic expression of the golli-myelin basic protein gene in the SJL/J mouse

Q71686658

An immunocytochemical study on the localization of S-100 protein in the retina of rats

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An important role for the chemokine macrophage inflammatory protein-1 alpha in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis

Q71829114

Thymic expression of myelin basic protein (MBP). Activation of MBP-specific T cells by thymic cells in the absence of exogenous MBP

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Multiple sclerosis. Immunomodulatory effects of human astrocytes on T cells

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Chemokine upregulation follows cytokine expression in chronic relapsing experimental autoimmune encephalomyelitis

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Neuronal FasL induces cell death of encephalitogenic T lymphocytes

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Astrocytes induce hyporesponses of myelin basic protein-reactive T and B cell function

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Targeting monocyte recruitment in CNS autoimmune disease

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Synchronous synthesis of alpha- and beta-chemokines by cells of diverse lineage in the central nervous system of mice with relapses of chronic experimental autoimmune encephalomyelitis

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Experimental autoimmune panencephalitis and uveoretinitis transferred to the Lewis rat by T lymphocytes specific for the S100 beta molecule, a calcium binding protein of astroglia.

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The distribution of Ia antigen in the lesions of rat acute experimental allergic encephalomyelitis

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Expression of autoimmune disease-related antigens by cells of the immune system

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The thymus and self-tolerance: co-existence of encephalitogenic S100 beta-specific T cells and their nominal autoantigen in the normal adult rat thymus

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Role of macrophages/microglia in multiple sclerosis and experimental allergic encephalomyelitis

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T cells specific for the myelin oligodendrocyte glycoprotein mediate an unusual autoimmune inflammatory response in the central nervous system.

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Apoptosis in the nervous system in experimental allergic encephalomyelitis

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Myelin basic proteins

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The effects of macrophage depletion on the clinical and pathologic expression of experimental allergic encephalomyelitis

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Selective chemokine mRNA accumulation in the rat spinal cord after contusion injury

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Cytokine regulation of CC and CXC chemokine expression by human astrocytes

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Cytokine induction of MIP-1 alpha and MIP-1 beta in human fetal microglia

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Myelin basic protein-related proteins in mouse brain and immune tissues

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The rapid isolation of clonable antigen-specific T lymphocyte lines capable of mediating autoimmune encephalomyelitis

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Immune invasion of the central nervous system parenchyma and experimental allergic encephalomyelitis, but not leukocyte extravasation from blood, are prevented in macrophage-depleted mice

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Detection by S-100 immunolabelling of interdigitating reticulum cells in human thymomas

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Migratory Activity and Functional Changes of Green Fluorescent Effector Cells before and during Experimental Autoimmune Encephalomyelitis

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The N-terminal domain of the myelin oligodendrocyte glycoprotein (MOG) induces acute demyelinating experimental autoimmune encephalomyelitis in the Lewis rat

Q61709774

Animal models

Q61709827

An immunohistochemical study of thymic epithelial tumors. III. The distribution of interdigitating reticulum cells and S-100 beta-positive small lymphocytes

Q68621838

Limiting dilution analysis of the frequency of antigen-reactive lymphocytes isolated from the central nervous system of Lewis rats with experimental allergic encephalomyelitis

Q68998856

T-lymphocyte entry into the central nervous system

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Chemokine monocyte chemoattractant protein-1 is expressed by astrocytes after mechanical injury to the brain

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T cell deletion in high antigen dose therapy of autoimmune encephalomyelitis

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P433

issue

P407

language of work or name

English

Q1860

P304

page(s)

185-197

P577

publication date

2004-01-01

P1433

published in

Journal of Experimental Medicine

Q3186912

P1476

title

The activation status of neuroantigen-specific T cells in the target organ determines the clinical outcome of autoimmune encephalomyelitis

P478

volume

199

Reverse relations

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