scholarly article | Q13442814 |
P2093 | author name string | Gary A Koretzky | |
Jonathan S Maltzman | |||
James L Clements | |||
Lisa Kovoor | |||
P2860 | cites work | Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells | Q24312990 |
Essential role for ZAP-70 in both positive and negative selection of thymocytes | Q24321424 | ||
The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling | Q28586244 | ||
An architectural perspective on signaling by the pre-, alphabeta and gammadelta T cell receptors | Q34180840 | ||
New perspectives on a developmental dilemma: the kinetic signaling model and the importance of signal duration for the CD4/CD8 lineage decision | Q34547220 | ||
Adaptors as central mediators of signal transduction in immune cells | Q35055629 | ||
Mice lacking major histocompatibility complex class I and class II molecules | Q36271130 | ||
Constitutive endocytosis and degradation of the pre-T cell receptor. | Q36369757 | ||
Unraveling a revealing paradox: Why major histocompatibility complex I-signaled thymocytes "paradoxically" appear as CD4+8lo transitional cells during positive selection of CD8+ T cells | Q36370932 | ||
Allelic exclusion of the T cell receptor beta locus requires the SH2 domain-containing leukocyte protein (SLP)-76 adaptor protein | Q36375439 | ||
CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity | Q36401360 | ||
Roles of the proline-rich domain in SLP-76 subcellular localization and T cell function. | Q40599629 | ||
Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stages | Q44151375 | ||
Impaired viability and profound block in thymocyte development in mice lacking the adaptor protein SLP-76. | Q47720762 | ||
Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development | Q47837774 | ||
Thymocyte stimulation by anti-TCR-β, but not by anti-TCR-α, leads to induction of developmental transcription program | Q49922658 | ||
Duration of TCR signaling controls CD4-CD8 lineage differentiation in vivo. | Q52093756 | ||
Cutting edge: identification of the targets of clonal deletion in an unmanipulated thymus. | Q52110901 | ||
A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. | Q52126962 | ||
PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes | Q58617364 | ||
Normal sequence of phenotypic transitions in one cohort of 5-bromo-2'-deoxyuridine-pulse-labeled thymocytes. Correlation with T cell receptor expression | Q70504035 | ||
Competitive displacement of pT alpha by TCR-alpha during TCR assembly prevents surface coexpression of pre-TCR and alpha beta TCR | Q73163114 | ||
Restoration of thymocyte development and function in zap-70-/- mice by the Syk protein tyrosine kinase | Q73767622 | ||
LAT links the pre-BCR to calcium signaling | Q73836551 | ||
SLP-76 expression is restricted to hemopoietic cells of monocyte, granulocyte, and T lymphocyte lineage and is regulated during T cell maturation and activation | Q77436813 | ||
Thymocyte stimulation by anti-TCR-beta, but not by anti-TCR-alpha, leads to induction of developmental transcription program | Q95817971 | ||
P433 | issue | 7 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | thymocyte | Q7799635 |
P304 | page(s) | 893-900 | |
P577 | publication date | 2005-09-26 | |
P1433 | published in | Journal of Experimental Medicine | Q3186912 |
P1476 | title | Conditional deletion reveals a cell-autonomous requirement of SLP-76 for thymocyte selection | |
P478 | volume | 202 |
Q36062659 | A mutation within the SH2 domain of slp-76 regulates the tissue distribution and cytokine production of iNKT cells in mice |
Q33640077 | Ablation of SLP-76 signaling after T cell priming generates memory CD4 T cells impaired in steady-state and cytokine-driven homeostasis. |
Q92556937 | Bridging the Gap: Modulatory Roles of the Grb2-Family Adaptor, Gads, in Cellular and Allergic Immune Responses |
Q36877284 | Compartmentalization of ITAM and integrin signaling by adapter molecules |
Q35072158 | Conditional deletion of SLP-76 in mature T cells abrogates peripheral immune responses |
Q37746483 | Coordination of receptor signaling in multiple hematopoietic cell lineages by the adaptor protein SLP-76 |
Q36055077 | Cutting edge: IL-2 signals determine the degree of TCR signaling necessary to support regulatory T cell proliferation in vivo |
Q42238133 | Cutting edge: rescue of pre-TCR but not mature TCR signaling in mice expressing membrane-targeted SLP-76. |
Q36155051 | Deconstructing Ras signaling in the thymus |
Q42737245 | Distinct roles for PTEN in prevention of T cell lymphoma and autoimmunity in mice |
Q36229486 | Distinct roles for Syk and ZAP-70 during early thymocyte development |
Q37618290 | ERK and cell death: ERK location and T cell selection |
Q36179534 | FADD regulates thymocyte development at the β-selection checkpoint by modulating Notch signaling |
Q88137939 | Fit αβ T-cell receptor suppresses leukemogenesis of Pten-deficient thymocytes |
Q51970307 | Impaired thymic selection in mice expressing altered levels of the SLP-76 adaptor protein. |
Q34119792 | Independent and cooperative roles of adaptor molecules in proximal signaling during FcepsilonRI-mediated mast cell activation |
Q34541698 | Loss of tonic T-cell receptor signals alters the generation but not the persistence of CD8+ memory T cells |
Q34060500 | Mislocalization of SLP-76 leads to aberrant inflammatory cytokine and autoantibody production |
Q36779409 | Murine natural killer immunoreceptors use distinct proximal signaling complexes to direct cell function. |
Q36604409 | Novel Molecular Insights into Classical and Alternative Activation States of Microglia as Revealed by Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC)-based Proteomics |
Q37971728 | Physiological and pathophysiological functions of SOCE in the immune system |
Q35883118 | Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling |
Q37376338 | Ras and extracellular signal-regulated kinase signaling in thymocytes and T cells. |
Q37270535 | Regulation of T cell integrin function by adapter proteins |
Q41892341 | SLP-76 is required for optimal CXCR4-stimulated T lymphocyte firm arrest to ICAM-1 under shear flow |
Q28298645 | SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond |
Q34648944 | T-cell receptor signaling to integrins |
Q34541692 | T-cell receptor signals direct the composition and function of the memory CD8+ T-cell pool |
Q37682609 | The Role of SH2 Domain-containing Leukocyte Phosphoprotein of 76 kDa in the Regulation of Immune Cell Development and Function |
Q38829466 | The SLP-76 Src homology 2 domain is required for T cell development and activation. |
Q28506969 | The actin regulator coronin 1A is mutant in a thymic egress-deficient mouse strain and in a patient with severe combined immunodeficiency |
Q30490766 | The adapter protein SLP-76 mediates "outside-in" integrin signaling and function in T cells |
Q37166773 | The essential role of LAT in thymocyte development during transition from the double-positive to single-positive stage |
Q37262507 | The importance of Src homology 2 domain-containing leukocyte phosphoprotein of 76 kilodaltons sterile-alpha motif domain in thymic selection and T-cell activation |
Q37802005 | Understanding signal integration through targeted mutations of an adapter protein |
Q33796333 | c-Cbl promotes T cell receptor-induced thymocyte apoptosis by activating the phosphatidylinositol 3-kinase/Akt pathway |
Q39021436 | iNKT cell cytotoxic responses control T-lymphoma growth in vitro and in vivo . |
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