| scholarly article | Q13442814 |
| review article | Q7318358 |
| P50 | author | Mark A Daniels | Q56427116 |
| P2093 | author name string | Emma Teixeiro | |
| P2860 | cites work | ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL | Q24306894 |
| Defective thymocyte maturation in p44 MAP kinase (Erk 1) knockout mice | Q28137811 | ||
| The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex | Q28141249 | ||
| BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis | Q28189945 | ||
| BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes | Q28203083 | ||
| LAT: a T lymphocyte adapter protein that couples the antigen receptor to downstream signaling pathways | Q28236195 | ||
| Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3 | Q28246420 | ||
| The fourth way? Harnessing aggressive tendencies in the thymus | Q28294493 | ||
| Thymocyte development in early growth response gene 1-deficient mice | Q28508522 | ||
| Transcriptional activation of known and novel apoptotic pathways by Nur77 orphan steroid receptor | Q28512848 | ||
| Pin1 mediates neural-specific activation of the mitochondrial apoptotic machinery | Q28582080 | ||
| Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis | Q28591401 | ||
| Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade | Q31929689 | ||
| ERK5 is a novel type of mitogen-activated protein kinase containing a transcriptional activation domain | Q33605384 | ||
| The dynamics of T cell receptor signaling: complex orchestration and the key roles of tempo and cooperation | Q33652505 | ||
| Cytochrome c release and apoptosis induced by mitochondrial targeting of nuclear orphan receptor TR3. | Q33914401 | ||
| ITAM multiplicity and thymocyte selection: how low can you go? | Q33967970 | ||
| Positive and negative selection of T cells | Q34157557 | ||
| RasGRP1 transduces low-grade TCR signals which are critical for T cell development, homeostasis, and differentiation. | Q34159142 | ||
| Diacylglycerol-dependent binding recruits PKCtheta and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes. | Q34360144 | ||
| Early phosphorylation kinetics of proteins involved in proximal TCR-mediated signaling pathways | Q34480890 | ||
| Examining multiprotein signaling complexes from all angles | Q34522144 | ||
| Digital signaling and hysteresis characterize ras activation in lymphoid cells | Q34929087 | ||
| Disruption of T cell signaling networks and development by Grb2 haploid insufficiency. | Q52137761 | ||
| Generalized resistance to thymic deletion in the NOD mouse; a polygenic trait characterized by defective induction of Bim. | Q53877408 | ||
| The lymphocyte function-associated antigen-1 receptor costimulates plasma membrane Ras via phospholipase D2 | Q57962185 | ||
| Ternary complex factor SAP-1 is required for Erk-mediated thymocyte positive selection | Q58484947 | ||
| Duration and Strength of Extracellular Signal-Regulated Kinase Signals Are Altered During Positive Versus Negative Thymocyte Selection | Q59123070 | ||
| The Ras/MAPK cascade and the control of positive selection | Q35076682 | ||
| Ras proteins: different signals from different locations | Q35120159 | ||
| A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3. | Q36078042 | ||
| Altered peptide ligands induce quantitatively but not qualitatively different intracellular signals in primary thymocytes | Q36171567 | ||
| T cell receptor-mediated signaling events in CD4+CD8+ thymocytes undergoing thymic selection: requirement of calcineurin activation for thymic positive selection but not negative selection. | Q36364509 | ||
| Inhibition of Nur77/Nurr1 leads to inefficient clonal deletion of self-reactive T cells | Q36366355 | ||
| Positive and negative selection invoke distinct signaling pathways. | Q36367050 | ||
| Knock-in mutation of the distal four tyrosines of linker for activation of T cells blocks murine T cell development | Q36369398 | ||
| Thymocyte maturation is regulated by the activity of the helix-loop-helix protein, E47 | Q36375680 | ||
| The JNK pathway regulates the In vivo deletion of immature CD4(+)CD8(+) thymocytes | Q36401296 | ||
| Conditional deletion reveals a cell-autonomous requirement of SLP-76 for thymocyte selection | Q36403552 | ||
| Modulation of thymic selection by expression of an immediate-early gene, early growth response 1 (Egr-1). | Q36404062 | ||
| Compartmentalized Ras/MAPK signaling | Q36427391 | ||
| Regulation of the Nur77 orphan steroid receptor in activation-induced apoptosis | Q36555939 | ||
| During negative selection, Nur77 family proteins translocate to mitochondria where they associate with Bcl-2 and expose its proapoptotic BH3 domain | Q36639961 | ||
| Non-redundant function of the MEK5-ERK5 pathway in thymocyte apoptosis | Q36793951 | ||
| Generating intrathymic microenvironments to establish T-cell tolerance. | Q36997113 | ||
| What do we know about the mechanisms of elimination of autoreactive T and B cells and what challenges remain | Q37008257 | ||
| Origin of the sharp boundary that discriminates positive and negative selection of thymocytes | Q37062064 | ||
| Protein kinase C-theta is required for efficient positive selection | Q37102903 | ||
| Non-deletional mechanisms of peripheral and central tolerance: studies with transgenic mice with tissue-specific expression of a foreign MHC class I antigen | Q37111712 | ||
| The Tec kinases Itk and Rlk regulate conventional versus innate T-cell development | Q37158945 | ||
| Apoptotic signals delivered through the T-cell receptor of a T-cell hybrid require the immediate-early gene nur77. | Q38311983 | ||
| Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling | Q39773899 | ||
| The mitogen-activated protein kinase scaffold KSR1 is required for recruitment of extracellular signal-regulated kinase to the immunological synapse | Q39896125 | ||
| ERK5 is involved in TCR-induced apoptosis through the modification of Nur77. | Q39989523 | ||
| T cell anergy is reversed by active Ras and is regulated by diacylglycerol kinase-alpha | Q40222415 | ||
| A motif in the alphabeta T-cell receptor controls positive selection by modulating ERK activity | Q40862851 | ||
| Zeta phosphorylation without ZAP-70 activation induced by TCR antagonists or partial agonists | Q41379043 | ||
| Nur77 transcription activity correlates with its apoptotic function in vivo | Q41701543 | ||
| Thymocyte selection is regulated by the helix-loop-helix inhibitor protein, Id3. | Q41717817 | ||
| Transcriptional regulation of tissue-specific genes by the ERK5 mitogen-activated protein kinase | Q42590095 | ||
| Akt inhibits the orphan nuclear receptor Nur77 and T-cell apoptosis | Q43662770 | ||
| Differential roles of ERK and p38 MAP kinase pathways in positive and negative selection of T lymphocytes. | Q44556255 | ||
| A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection | Q44593628 | ||
| Requirement for the orphan steroid receptor Nur77 in apoptosis of T-cell hybridomas | Q46064858 | ||
| Kinase suppressor of Ras couples Ras to the ERK cascade during T cell development | Q46362295 | ||
| The role of erk1 and erk2 in multiple stages of T cell development. | Q50954940 | ||
| Selective requirement for MAP kinase activation in thymocyte differentiation. | Q51126213 | ||
| Subcellular localization determines MAP kinase signal output. | Q51470882 | ||
| Immature CD4+CD8+ thymocytes and mature T cells regulate Nur77 distinctly in response to TCR stimulation. | Q52002861 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cell death | Q2383867 |
| P304 | page(s) | 30-38 | |
| P577 | publication date | 2009-10-16 | |
| P1433 | published in | FEBS Journal | Q1388041 |
| P1476 | title | ERK and cell death: ERK location and T cell selection | |
| P478 | volume | 277 |
| Q35021753 | Activation associated ERK1/2 signaling impairments in CD8+ T cells co-localize with blunted polyclonal and HIV-1 specific effector functions in early untreated HIV-1 infection. |
| Q38806418 | An immediate-late gene expression module decodes ERK signal duration |
| Q90468352 | BRAF and MEK inhibitors differentially affect nivolumab-induced T cell activation by modulating the TCR and AKT signaling pathways |
| Q38956056 | Concomitant evaluation of PMA+ionomycin-induced kinase phosphorylation and cytokine production in T cell subsets by flow cytometry. |
| Q98158987 | Dual effects of active ERK in cancer: A potential target for enhancing radiosensitivity |
| Q47825435 | Fine-tuning of thymocyte development by ubiquitination-mediated stability control of the ESCRT protein CHMP5. |
| Q35531548 | HIV-1 infection abrogates CD8+ T cell mitogen-activated protein kinase signaling responses. |
| Q38712257 | Helicobacter pylori Secreted Protein HP1286 Triggers Apoptosis in Macrophages via TNF-Independent and ERK MAPK-Dependent Pathways |
| Q33924459 | Helicobacter pylori induces ERK-dependent formation of a phospho-c-Fos c-Jun activator protein-1 complex that causes apoptosis in macrophages |
| Q38953223 | Increased expression of insulin-like growth factor-1 receptor is correlated with worse survival in canine appendicular osteosarcoma. |
| Q33873144 | Pathways analysis of molecular markers in chronic sinusitis with polyps |
| Q92034221 | RRAS2 shapes the TCR repertoire by setting the threshold for negative selection |
| Q90301425 | Synovial Predictors of Differentiation to Definite Arthritis in Patients With Seronegative Undifferentiated Peripheral Inflammatory Arthritis: microRNA Signature, Histological, and Ultrasound Features |
| Q46179229 | The EphB6 receptor is overexpressed in pediatric T cell acute lymphoblastic leukemia and increases its sensitivity to doxorubicin treatment |
| Q34771536 | The interplay of NR4A receptors and the oncogene-tumor suppressor networks in cancer |
| Q47115001 | The role of aberrant expression of T cell miRNAs affected by TNF-α in the immunopathogenesis of rheumatoid arthritis. |
| Q35826021 | Thymic negative selection is functional in NOD mice |
| Q38117370 | Weft, warp, and weave: the intricate tapestry of calcium channels regulating T lymphocyte function |
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