Modulation of thymic selection by expression of an immediate-early gene, early growth response 1 (Egr-1).

scientific article

Modulation of thymic selection by expression of an immediate-early gene, early growth response 1 (Egr-1). is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1084/JEM.188.4.715
P932PMC publication ID2213358
P698PubMed publication ID9705953
P5875ResearchGate publication ID13579258

P2093author name stringMiyazaki T
Lemonnier FA
P2860cites workBcl-2 Rescues T Lymphopoiesis in Interleukin-7 Receptor–Deficient MiceQ28508137
Bcl-2 can rescue T lymphocyte development in interleukin-7 receptor-deficient mice but not in mutant rag-1-/- miceQ28513839
Mice lacking MHC class II moleculesQ28588991
Independent modes of natural killing distinguished in mice lacking Lag3Q28591539
Differential requirements for survival and proliferation of CD8 naïve or memory T cellsQ34430192
Peripheral selection of the T cell repertoireQ34880495
Positive and negative selection of T cells in T-cell receptor transgenic mice expressing a bcl-2 transgeneQ35045775
Functionally conformed free class I heavy chains exist on the surface of beta 2 microglobulin negative cellsQ36231782
Positive selection of CD8+ T cells induced by major histocompatibility complex binding peptides in fetal thymic organ cultureQ36361722
Induction of the early growth response (Egr) family of transcription factors during thymic selectionQ36376794
Self-MHC-restricted peptides recognized by an alloreactive T lymphocyte cloneQ36813012
Recognition of beta 2-microglobulin-negative (beta 2m-) T-cell blasts by natural killer cells from normal but not from beta 2m- mice: nonresponsiveness controlled by beta 2m- bone marrow in chimeric miceQ37624987
Developmental biology of T cells in T cell-receptor transgenic miceQ37925543
Two distinct steps during thymocyte maturation from CD4-CD8- to CD4+CD8+ distinguished in the early growth response (Egr)-1 transgenic mice with a recombinase-activating gene-deficient backgroundQ38343088
Immediate-early genes induced by antigen receptor stimulationQ40404843
Positive selection of thymocytes bearing alpha beta T cell receptors.Q41429671
Positive selection of T cells: fastidious or promiscuous?Q41429700
HLA-A2.1-restricted education and cytolytic activity of CD8(+) T lymphocytes from beta2 microglobulin (beta2m) HLA-A2.1 monochain transgenic H-2Db beta2m double knockout miceQ41903577
Mutations in T-cell antigen receptor genes alpha and beta block thymocyte development at different stagesQ44151375
A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selectionQ44593628
Tolerance in T-cell-receptor transgenic mice involves deletion of nonmature CD4+8+ thymocytesQ44851100
Selective development of CD4+ T cells in transgenic mice expressing a class II MHC-restricted antigen receptorQ46155874
MHC Class I Deficiency: Susceptibility to Natural Killer (NK) Cells and Impaired NK ActivityQ46345857
Beta 2-microglobulin deficient mice lack CD4-8+ cytolytic T cells.Q52483263
bcl-2 transgene inhibits T cell death and perturbs thymic self-censorshipQ57338704
Peptide contributes to the specificity of positive selection of CD8+ T cells in the thymusQ63363368
Involvement of the same region of the T cell antigen receptor in thymic selection and foreign peptide recognitionQ67848563
Tumor induction and tissue atrophy in mice lacking E2F-1Q71129252
E2F-1 functions in mice to promote apoptosis and suppress proliferationQ71129257
Growth and differentiation proceeds normally in cells deficient in the immediate early gene NGFI-AQ72191159
CD8 T cells from major histocompatibility complex class II-deficient mice respond vigorously to class II molecules in a primary mixed lymphocyte reactionQ73101489
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectimmediate early geneQ409638
P304page(s)715-723
P577publication date1998-08-01
P1433published inJournal of Experimental MedicineQ3186912
P1476titleModulation of thymic selection by expression of an immediate-early gene, early growth response 1 (Egr-1).
P478volume188

Reverse relations

cites work (P2860)
Q34829321Costimulatory signals are required for induction of transcription factor Nur77 during negative selection of CD4(+)CD8(+) thymocytes
Q37618290ERK and cell death: ERK location and T cell selection
Q84819743Early growth response 2 regulates the survival of thymocytes during positive selection
Q33886752Early growth response gene-2 (Egr-2) regulates the development of B and T cells
Q36992618Early growth response genes regulate B cell development, proliferation, and immune response
Q38348879Early growth response protein-1 (Egr-1) is preferentially expressed in T helper type 2 (Th2) cells and is involved in acute transcription of the Th2 cytokine interleukin-4.
Q36982963Egr2 is required for Bcl-2 induction during positive selection
Q40648491Expression profiling of a transformed thymocyte cell line undergoing maturation in vitro identifies multiple genes involved in positive selection
Q33608726Foxp1 is an essential transcriptional regulator for the generation of quiescent naive T cells during thymocyte development.
Q47832919Nab2 maintains thymus cellularity with aging and stress
Q36685758Opposing regulation of T cell function by Egr-1/NAB2 and Egr-2/Egr-3.
Q36382766Recent insights into the signals that control alphabeta/gammadelta-lineage fate.
Q33941976Regulation of T cell development in the thymus
Q31929689Regulation of the helix-loop-helix proteins, E2A and Id3, by the Ras-ERK MAPK cascade
Q73694695Reversible activation of c-Myc in thymocytes enhances positive selection and induces proliferation and apoptosis in vitro
Q35832518Selection of the T-cell repertoire: receptor-controlled checkpoints in T-cell development
Q57339913Serum Response Factor Contributes Selectively to Lymphocyte Development
Q47422876T cell stimulation in the absence of exogenous antigen: a T cell signal is induced by both MHC‐dependent and ‐independent mechanisms
Q35213773T-cell activation and early gene response in dogs
Q58484947Ternary complex factor SAP-1 is required for Erk-mediated thymocyte positive selection
Q35076682The Ras/MAPK cascade and the control of positive selection
Q37310026The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells
Q46268969The regulation and function of the Id proteins in lymphocyte development
Q85931827The roles of Egr-2 in autoimmune diseases
Q35794622Transcriptional control of thymocyte positive selection
Q82950784c-Fos enhances the survival of thymocytes during positive selection by upregulating Bcl-2

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