scholarly article | Q13442814 |
P356 | DOI | 10.4049/JIMMUNOL.167.9.4966 |
P8608 | Fatcat ID | release_frpiowlyvvamrfn7rjvinbdb4q |
P698 | PubMed publication ID | 11673503 |
P50 | author | Alison M Michie | Q38321055 |
Pamela Ohashi | Q56891473 | ||
P2093 | author name string | J C Zúñiga-Pflücker | |
D Bouchard | |||
A Zakarian | |||
S Mariathasan | |||
P433 | issue | 9 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | thymocyte | Q7799635 |
P304 | page(s) | 4966-4973 | |
P577 | publication date | 2001-11-01 | |
P1433 | published in | Journal of Immunology | Q3521441 |
P1476 | title | Duration and strength of extracellular signal-regulated kinase signals are altered during positive versus negative thymocyte selection | |
P478 | volume | 167 |
Q34015960 | A requirement for sustained ERK signaling during thymocyte positive selection in vivo |
Q28513626 | A role for mitogen-activated protein kinase(Erk1/2) activation and non-selective pore formation in P2X7 receptor-mediated thymocyte death |
Q36186047 | A voltage-gated sodium channel is essential for the positive selection of CD4(+) T cells |
Q46680553 | Autocrine activation of EGF receptor promotes oscillation of glutamate-induced calcium increase in astrocytes cultured in rat cerebral cortex |
Q40520531 | B-Raf contributes to sustained extracellular signal-regulated kinase activation associated with interleukin-2 production stimulated through the T cell receptor. |
Q28585363 | B-Raf is required for positive selection and survival of DP cells, but not for negative selection of SP cells |
Q36414539 | Beta-catenin/Tcf determines the outcome of thymic selection in response to alphabetaTCR signaling |
Q93017603 | Central CD4+ T cell tolerance: deletion versus regulatory T cell differentiation |
Q36960980 | Chimerism and tetragametic chimerism in humans: implications in autoimmunity, allorecognition and tolerance |
Q43152094 | Complementation in trans of altered thymocyte development in mice expressing mutant forms of the adaptor molecule SLP76. |
Q33763027 | Cutting edge: Extracellular signal-related kinase is not required for negative selection of developing T cells |
Q36820360 | Diacylglycerol kinases: regulated controllers of T cell activation, function, and development |
Q37618290 | ERK and cell death: ERK location and T cell selection |
Q48892401 | ERK mediates activity dependent neuronal complexity via sustained activity and CREB-mediated signaling |
Q39989523 | ERK5 is involved in TCR-induced apoptosis through the modification of Nur77. |
Q40553683 | Enhancement of MEK/ERK signaling promotes glucocorticoid resistance in CD4+ T cells |
Q47113506 | Fine-Tuning of Optimal TCR Signaling in Tumor-Redirected CD8 T Cells by Distinct TCR Affinity-Mediated Mechanisms. |
Q40344719 | Glial cell line-derived neurotrophic factor promotes the arborization of cultured striatal neurons through the p42/p44 mitogen-activated protein kinase pathway |
Q47298570 | Grb2-Mediated Recruitment of USP9X to LAT Enhances Themis Stability following Thymic Selection. |
Q37977320 | How the TCR balances sensitivity and specificity for the recognition of self and pathogens. |
Q40663741 | IKCa1 activity is required for cell shrinkage, phosphatidylserine translocation and death in T lymphocyte apoptosis |
Q24338926 | Interchangeability of Themis1 and Themis2 in thymocyte development reveals two related proteins with conserved molecular function |
Q34293064 | Kinase suppressor of Ras 1 is required for full ERK activation in thymocytes but not for thymocyte selection. |
Q42738024 | LAT and NTAL mediate immunoglobulin E-induced sustained extracellular signal-regulated kinase activation critical for mast cell survival |
Q26781296 | Lower Affinity T Cells are Critical Components and Active Participants of the Immune Response |
Q99635125 | MicroRNA miR-181-A Rheostat for TCR Signaling in Thymic Selection and Peripheral T-Cell Function |
Q35145197 | Multiple model-informed open-loop control of uncertain intracellular signaling dynamics |
Q34974604 | Mutation of the phospholipase C-gamma1-binding site of LAT affects both positive and negative thymocyte selection |
Q96289890 | Negative control of diacylglycerol kinase ζ-mediated inhibition of T cell receptor signaling by nuclear sequestration in mice |
Q35136005 | Negative selection--clearing out the bad apples from the T-cell repertoire |
Q40511527 | Neurotensin and EGF induce synergistic stimulation of DNA synthesis by increasing the duration of ERK signaling in ductal pancreatic cancer cells |
Q36793951 | Non-redundant function of the MEK5-ERK5 pathway in thymocyte apoptosis |
Q34118353 | PKCtheta is necessary for efficient activation of NFkappaB, NFAT, and AP-1 during positive selection of thymocytes |
Q37631699 | Positive and negative regulation of antigen receptor signaling by the Shc family of protein adapters |
Q34562749 | Programmed death-1 (PD-1):PD-ligand 1 interactions inhibit TCR-mediated positive selection of thymocytes |
Q37102903 | Protein kinase C-theta is required for efficient positive selection |
Q42831514 | Protein kinase D potentiates DNA synthesis induced by Gq-coupled receptors by increasing the duration of ERK signaling in swiss 3T3 cells |
Q34159142 | RasGRP1 transduces low-grade TCR signals which are critical for T cell development, homeostasis, and differentiation. |
Q41767300 | Reciprocal encoding of signal intensity and duration in a glucose-sensing circuit |
Q35084280 | Regulation of thymocyte development: only the meek survive |
Q36946379 | Role of diacylglycerol kinases in T cell development and function |
Q37549648 | SLAP deficiency increases TCR avidity leading to altered repertoire and negative selection of cognate antigen-specific CD8+ T cells |
Q34778134 | Signaling in thymic selection |
Q36954496 | Synergistic control of T cell development and tumor suppression by diacylglycerol kinase alpha and zeta |
Q90301425 | Synovial Predictors of Differentiation to Definite Arthritis in Patients With Seronegative Undifferentiated Peripheral Inflammatory Arthritis: microRNA Signature, Histological, and Ultrasound Features |
Q44537867 | T cell receptor-stimulated generation of hydrogen peroxide inhibits MEK-ERK activation and lck serine phosphorylation |
Q34659128 | T-cell development and the CD4-CD8 lineage decision |
Q34716347 | T-cell signalling and autoimmunity: molecular mechanisms of disease |
Q40264104 | TCR ligand avidity determines the mode of B-Raf/Raf-1/ERK activation leading to the activation of human CD4+ T cell clone. |
Q58484947 | Ternary complex factor SAP-1 is required for Erk-mediated thymocyte positive selection |
Q42941711 | The molecular scaffold kinase suppressor of Ras 1 (KSR1) regulates adipogenesis |
Q47115001 | The role of aberrant expression of T cell miRNAs affected by TNF-α in the immunopathogenesis of rheumatoid arthritis. |
Q24657605 | Themis controls thymocyte selection through regulation of T cell antigen receptor-mediated signaling |
Q37687058 | Themis sets the signal threshold for positive and negative selection in T-cell development |
Q48220577 | Thymic progenitors of TCRαβ+ CD8αα intestinal intraepithelial lymphocytes require RasGRP1 for development |
Q39773899 | Thymic selection threshold defined by compartmentalization of Ras/MAPK signalling |
Q38503829 | Topology, dynamics, and heterogeneity in immune signaling |
Q37752795 | Towards a molecular understanding of the differential signals regulating alphabeta/gammadelta T lineage choice |