Critical role of Wnt/β-catenin signaling in driving epithelial ovarian cancer platinum resistance

scientific article

Critical role of Wnt/β-catenin signaling in driving epithelial ovarian cancer platinum resistance is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.18632/ONCOTARGET.4690
P932PMC publication ID4695147
P698PubMed publication ID26125441
P5875ResearchGate publication ID279628892

P2093author name stringSteven Waggoner
Kristine Zanotti
Analisa DiFeo
Kimberly Resnick
Sareena Singh
Anil Belur Nagaraj
Peronne Joseph
Raymond Redline
Amy Armstrong
Olga Kovalenko
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Cancer statistics, 2014Q27861018
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Genetic and pharmacologic inhibition of β-catenin targets imatinib-resistant leukemia stem cells in CML.Q42140104
Integrating genomic, epigenomic, and transcriptomic features reveals modular signatures underlying poor prognosis in ovarian cancer.Q44879961
Cancer and stem cell biology: how tightly intertwined?Q46026703
Cancer stem cell definitions and terminology: the devil is in the details.Q53140630
Evolution of platinum resistance in high-grade serous ovarian cancerQ58613175
beta-catenin nuclear localization is associated with grade in ovarian serous carcinomaQ73153525
Lgr5 marks stem/progenitor cells in ovary and tubal epitheliaQ88222343
Wnt signaling mediates regional specification in the vertebrate faceQ28588683
WNT signalling pathways as therapeutic targets in cancerQ29615666
Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathwaysQ29615855
β-Catenin-regulated ALDH1A1 is a target in ovarian cancer spheroidsQ30370274
Linking proteomic and transcriptional data through the interactome and epigenome reveals a map of oncogene-induced signalingQ30588679
A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected]Q31106002
Stem cell pathways contribute to clinical chemoresistance in ovarian cancerQ34092005
Ovarian surface epithelium at the junction area contains a cancer-prone stem cell nicheQ34331396
Targeting aldehyde dehydrogenase cancer stem cells in ovarian cancerQ34420393
Ovarian cancer stem cell-like side populations are enriched following chemotherapy and overexpress EZH2.Q34569371
ALDH1-high ovarian cancer stem-like cells can be isolated from serous and clear cell adenocarcinoma cells, and ALDH1 high expression is associated with poor prognosisQ34769665
Ovarian cancer stem cells are enriched in side population and aldehyde dehydrogenase bright overlapping populationQ34962206
Aldehyde dehydrogenase in combination with CD133 defines angiogenic ovarian cancer stem cells that portend poor patient survivalQ35022205
Diverse mechanisms for activation of Wnt signalling in the ovarian tumour microenvironmentQ35098085
Acquired cisplatin resistance in human ovarian cancer cells is associated with enhanced repair of cisplatin-DNA lesions and reduced drug accumulationQ35818950
Determining mammosphere-forming potential: application of the limiting dilution analysisQ36192058
Targeting Notch, a key pathway for ovarian cancer stem cells, sensitizes tumors to platinum therapyQ36378255
Wnt signaling in ovarian tumorigenesisQ36953825
Wnt/β-catenin Signaling in Normal and Cancer Stem Cells.Q37132716
WNT signalling in the immune system: WNT is spreading its wingsQ37212748
microRNA-181a has a critical role in ovarian cancer progression through the regulation of the epithelial-mesenchymal transition.Q37497239
Genomic and transcriptomic plasticity in treatment-naive ovarian cancerQ37550198
Wnt/β-catenin pathway as a potential prognostic and predictive marker in patients with advanced ovarian cancerQ37589190
Targeting Wnt signaling: can we safely eradicate cancer stem cells?Q37763415
Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathwaysQ37820099
Cancerous ovarian stem cells: obscure targets for therapy but relevant to chemoresistance.Q38034167
The role of aldehyde dehydrogenase (ALDH) in cancer drug resistance.Q38110652
Ovarian cancer stem cells: Molecular concepts and relevance as therapeutic targetsQ38118011
The Wnt/β-catenin pathway in ovarian cancer: a review.Q38152532
Investigating molecular profiles of ovarian cancer: an update on cancer stem cells.Q38203882
Inhibition of Wnt/β-catenin pathway by niclosamide: a therapeutic target for ovarian cancer.Q39003793
ALDH1-bright epithelial ovarian cancer cells are associated with CD44 expression, drug resistance, and poor clinical outcomeQ39417011
Cisplatin treatment of primary and metastatic epithelial ovarian carcinomas generates residual cells with mesenchymal stem cell-like profile.Q39535066
β-Catenin mediates the establishment and drug resistance of MLL leukemic stem cellsQ39620290
The Origins and Implications of Intratumor HeterogeneityQ40015673
P433issue27
P407language of work or nameEnglishQ1860
P921main subjectplatinumQ880
ovarian cancerQ172341
P304page(s)23720-23734
P577publication date2015-06-29
P1433published inOncotargetQ1573155
P1476titleCritical role of Wnt/β-catenin signaling in driving epithelial ovarian cancer platinum resistance
P478volume6

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