review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1158/1078-0432.CCR-09-2943 |
P698 | PubMed publication ID | 20530697 |
P2093 | author name string | Michael Kahn | |
Fumi Takahashi-Yanaga | |||
P433 | issue | 12 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | neoplastic stem cells | Q1638475 |
P304 | page(s) | 3153-3162 | |
P577 | publication date | 2010-06-08 | |
P1433 | published in | Clinical Cancer Research | Q332253 |
P1476 | title | Targeting Wnt signaling: can we safely eradicate cancer stem cells? | |
P478 | volume | 16 |
Q26739665 | A Second WNT for Old Drugs: Drug Repositioning against WNT-Dependent Cancers |
Q38867217 | A bispecific EpCAM/CD133-targeted toxin is effective against carcinoma |
Q39392231 | A new validated mathematical model of the Wnt signalling pathway predicts effective combinational therapy by sFRP and Dkk. |
Q33577624 | A unified model of the hierarchical and stochastic theories of gastric cancer |
Q47136896 | ALX4, an epigenetically down regulated tumor suppressor, inhibits breast cancer progression by interfering Wnt/β-catenin pathway |
Q36341597 | Aberrantly expressed miR-582-3p maintains lung cancer stem cell-like traits by activating Wnt/β-catenin signalling |
Q39290765 | Adamantinomatous craniopharyngiomas express tumor stem cell markers in cells with activated Wnt signaling: further evidence for the existence of a tumor stem cell niche? |
Q37124069 | Adenomatous polyposis coli (APC) regulates miR17-92 cluster through β-catenin pathway in colorectal cancer |
Q26751344 | Advances in targeted and immunobased therapies for colorectal cancer in the genomic era |
Q37583804 | Aldehyde dehydrogenases in cancer stem cells: potential as therapeutic targets |
Q35863203 | Altering cancer transcriptomes using epigenomic inhibitors |
Q64226435 | Amine derivatives of furocoumarin induce melanogenesis by activating Akt/GSK-3β/β-catenin signal pathway |
Q34311859 | An agent-based model of cancer stem cell initiated avascular tumour growth and metastasis: the effect of seeding frequency and location |
Q55091102 | Anti-oncogenic activity of Chibby in the development of human nasopharyngeal carcinoma. |
Q36466583 | Artemin stimulates radio- and chemo-resistance by promoting TWIST1-BCL-2-dependent cancer stem cell-like behavior in mammary carcinoma cells |
Q46014740 | Association of common gene variants in the WNT/β-catenin pathway with colon cancer recurrence. |
Q38757074 | Biological and clinical significance of cancer stem cell plasticity |
Q35131282 | Biphasic role of chondroitin sulfate in cardiac differentiation of embryonic stem cells through inhibition of Wnt/β-catenin signaling |
Q37839530 | Breast cancer stem cells: treatment resistance and therapeutic opportunities |
Q37054060 | CBP Activity Mediates Effects of the Histone Deacetylase Inhibitor Butyrate on WNT Activity and Apoptosis in Colon Cancer Cells |
Q39289235 | CBP/Catenin antagonists: Targeting LSCs' Achilles heel |
Q35067887 | CD151-α3β1 integrin complexes suppress ovarian tumor growth by repressing slug-mediated EMT and canonical Wnt signaling. |
Q26799062 | CREB-binding protein, p300, butyrate, and Wnt signaling in colorectal cancer |
Q38796646 | Can Stopping Nerves, Stop Cancer? |
Q27022017 | Can nanomedicines kill cancer stem cells? |
Q35591995 | Can we safely target the WNT pathway? |
Q39773200 | Cancer Stem Cells and Pediatric Solid Tumors |
Q46570572 | Cancer Stem Cells in Head and Neck Carcinomas: Identification and Possible Therapeutic Implications. |
Q27024816 | Cancer Stem and Progenitor-Like Cells as Pharmacological Targets in Breast Cancer Treatment |
Q34778345 | Cancer cells acquire a drug resistant, highly tumorigenic, cancer stem-like phenotype through modulation of the PI3K/Akt/β-catenin/CBP pathway. |
Q38007261 | Cancer stem cells and epithelial-mesenchymal transition: concepts and molecular links |
Q48278683 | Cancer stem cells as targets for immunotherapy |
Q28081844 | Cancer stem cells in basic science and in translational oncology: can we translate into clinical application? |
Q27024651 | Cancer stem cells in colorectal cancer from pathogenesis to therapy: controversies and perspectives |
Q38161332 | Cancer stem cells in head and neck cancer |
Q37796629 | Cancer stem cells: a new framework for the design of tumor therapies. |
Q37861207 | Cancer stem cells: the development of new cancer therapeutics. |
Q28543151 | Canonical Wnt pathway inhibitor ICG-001 induces cytotoxicity of multiple myeloma cells in Wnt-independent manner |
Q59135502 | Celecoxib in breast cancer prevention and therapy |
Q33688897 | Celecoxib suppresses hepatoma stemness and progression by up-regulating PTEN. |
Q49292906 | Cell-type specific potent Wnt signaling blockade by bispecific antibody |
Q27026428 | Chemopreventive drugs: mechanisms via inhibition of cancer stem cells in colorectal cancer |
Q44421418 | Circulating stem cell-like epithelial cell adhesion molecule-positive tumor cells indicate poor prognosis of hepatocellular carcinoma after curative resection |
Q39027075 | Clinicopathological significance of WIF1 hypermethylation in NSCLC, a meta-analysis and literature review |
Q26777882 | Common stemness regulators of embryonic and cancer stem cells |
Q38850621 | Concise Review: Stem Cells and Epithelial-Mesenchymal Transition in Cancer: Biological Implications and Therapeutic Targets. |
Q37552660 | Controversies in cancer stem cells: targeting embryonic signaling pathways |
Q37833922 | Coordinating changes in cell adhesion and phenotype during EMT-like processes in cancer. |
Q36414274 | Critical role of Wnt/β-catenin signaling in driving epithelial ovarian cancer platinum resistance |
Q47697601 | Crosstalk between long non-coding RNAs and Wnt/β-catenin signalling in cancer. |
Q35864226 | Current trends in targeted therapies for glioblastoma multiforme |
Q48784827 | Daucosterol Inhibits the Proliferation, Migration, and Invasion of Hepatocellular Carcinoma Cells via Wnt/β-Catenin Signaling. |
Q35219277 | Denervation suppresses gastric tumorigenesis |
Q52582285 | Deptor is a novel target of Wnt/β-catenin/c-Myc and contributes to colorectal cancer cell growth. |
Q34018958 | Dickkopf1 regulates fate decision and drives breast cancer stem cells to differentiation: an experimentally supported mathematical model |
Q46475690 | Dietary compound isoliquiritigenin targets GRP78 to chemosensitize breast cancer stem cells via β-catenin/ABCG2 signaling |
Q34537513 | Differences in coreceptor specificity contribute to alternative tropism of HIV-1 subtype C for CD4(+) T-cell subsets, including stem cell memory T-cells |
Q91816312 | Differential effects, on oncogenic pathway signalling, by derivatives of the HNF4 α inhibitor BI6015 |
Q35560868 | Discovery of potent, orally bioavailable, small-molecule inhibitors of WNT signaling from a cell-based pathway screen. |
Q38687471 | Discovery of small molecule inhibitors of the Wnt/β-catenin signaling pathway by targeting β-catenin/Tcf4 interactions |
Q35098085 | Diverse mechanisms for activation of Wnt signalling in the ovarian tumour microenvironment |
Q38887098 | Downregulation of VANGL1 inhibits cellular invasion rather than cell motility in hepatocellular carcinoma cells without stimulation |
Q37840943 | Drug discovery approaches to target Wnt signaling in cancer stem cells |
Q38012254 | Drugging Wnt signalling in cancer |
Q38275614 | E-cadherin's role in development, tissue homeostasis and disease: Insights from mouse models: Tissue-specific inactivation of the adhesion protein E-cadherin in mice reveals its functions in health and disease |
Q64136480 | EGF-induced nuclear localization of SHCBP1 activates β-catenin signaling and promotes cancer progression |
Q38664528 | Effects of pulsed electromagnetic fields on postmenopausal osteoporosis |
Q38978495 | Eliminating Cancer Stem Cells by Targeting Embryonic Signaling Pathways |
Q59795305 | Endogenous and exogenous galectin-3 promote the adhesion of tumor cells with low expression of MUC1 to HUVECs through upregulation of N-cadherin and CD44 |
Q37869838 | Eradication of breast cancer cells in patients with distant metastasis: the finishing touches? |
Q99241353 | Estrogen receptor-β signaling induces cisplatin resistance in bladder cancer |
Q37417591 | Evidence of a role for CD44 and cell adhesion in mediating resistance to lenalidomide in multiple myeloma: therapeutic implications |
Q37334480 | Expression Patterns of the Wnt Pathway Inhibitors Dickkopf3 and Secreted Frizzled-Related Proteins 1 and 4 in Endometrial Endometrioid Adenocarcinoma: An NRG Oncology/Gynecologic Oncology Group Study |
Q37066536 | Expression of Wnt3 activates Wnt/β-catenin pathway and promotes EMT-like phenotype in trastuzumab-resistant HER2-overexpressing breast cancer cells |
Q26849278 | Frizzled7 as an emerging target for cancer therapy |
Q24313470 | Functional analysis of novel phosphorylation sites of CREB-binding protein using mass spectrometry and mammalian two-hybrid assays |
Q64064084 | Functional and transcriptomic characterization of carboplatin-resistant A2780 ovarian cancer cell line |
Q55000578 | Functional miRNAs in breast cancer drug resistance. |
Q36561625 | GalNAc-T14 promotes metastasis through Wnt dependent HOXB9 expression in lung adenocarcinoma |
Q35795934 | Gastric cancer stem cells: evidence, potential markers, and clinical implications |
Q36737793 | Gastric stem cells and gastric cancer stem cells |
Q37959323 | Gastroenteropancreatic neuroendocrine tumor cancer stem cells: do they exist? |
Q28483663 | Gene expression profiling of liver cancer stem cells by RNA-sequencing |
Q34765296 | Genetic regulation of prostate development |
Q37815136 | Genetically informed lung cancer medicine |
Q31112063 | Gpr177 deficiency impairs mammary development and prohibits Wnt-induced tumorigenesis |
Q38014365 | Gut stem cells in tissue renewal and disease: methods, markers, and myths |
Q37646541 | HIV-1 persistence in CD4+ T cells with stem cell-like properties |
Q37936020 | Head and neck cancer stem cells |
Q36801771 | Honokiol Eliminates Human Oral Cancer Stem-Like Cells Accompanied with Suppression of Wnt/ β -Catenin Signaling and Apoptosis Induction |
Q92670011 | Hypothesis: Retinoblastoma protein inactivation mediates effects of histone deacetylase inhibitor-induced Wnt hyperactivation in colorectal cancer cells |
Q41273119 | ICG-001 suppresses growth of gastric cancer cells and reduces chemoresistance of cancer stem cell-like population |
Q30384345 | Identification and characterization of a novel small-molecule inhibitor of β-catenin signaling |
Q36080584 | Identification of V-ATPase as a molecular sensor of SOX11-levels and potential therapeutic target for mantle cell lymphoma |
Q37708736 | Identification of a new class of WNT1 inhibitor: Cancer cells migration, G-quadruplex stabilization and target validation |
Q51608321 | Identification of carcinogenic potential-associated molecular mechanisms in CD133(+) A549 cells based on microRNA profiles. |
Q90640291 | Immunotherapy: Newer Therapeutic Armamentarium against Cancer Stem Cells |
Q39208071 | In vivo and in vitro effects of a novel anti-Dkk1 neutralizing antibody in multiple myeloma. |
Q41612992 | Inhibition of FAK kinase activity preferentially targets cancer stem cells |
Q39003793 | Inhibition of Wnt/β-catenin pathway by niclosamide: a therapeutic target for ovarian cancer. |
Q28481465 | Inhibition of melanogenesis by the pyridinyl imidazole class of compounds: possible involvement of the Wnt/β-catenin signaling pathway |
Q36919396 | Inhibition of the Wnt palmitoyltransferase porcupine suppresses cell growth and downregulates the Wnt/β-catenin pathway in gastric cancer |
Q49569420 | Insufficient microwave ablation-induced promotion of distant metastasis is suppressed by β-catenin pathway inhibition in breast cancer |
Q35553581 | Integrated genomic analysis of relapsed childhood acute lymphoblastic leukemia reveals therapeutic strategies |
Q35203271 | Intra-tumour signalling entropy determines clinical outcome in breast and lung cancer |
Q34995814 | Investigation of 3-aryl-pyrimido[5,4-e][1,2,4]triazine-5,7-diones as small molecule antagonists of β-catenin/TCF transcription |
Q26829595 | Is Wilms tumor a candidate neoplasia for treatment with WNT/β-catenin pathway modulators?--A report from the renal tumors biology-driven drug development workshop |
Q39055537 | Isolation, identification, and characterization of cancer stem cells: A review |
Q38786359 | Kat3 coactivators in somatic stem cells and cancer stem cells: biological roles, evolution, and pharmacologic manipulation. |
Q41242686 | LHX6, An Independent Prognostic Factor, Inhibits Lung Adenocarcinoma Progression through Transcriptional Silencing of β-catenin |
Q28555025 | Long-Lasting WNT-TCF Response Blocking and Epigenetic Modifying Activities of Withanolide F in Human Cancer Cells |
Q39248886 | Lycopene synergistically enhances quinacrine action to inhibit Wnt-TCF signaling in breast cancer cells through APC. |
Q38622874 | Mechanisms of tumour resistance against chemotherapeutic agents in veterinary oncology |
Q64081442 | MiR-1180 from bone marrow-derived mesenchymal stem cells induces glycolysis and chemoresistance in ovarian cancer cells by upregulating the Wnt signaling pathway |
Q35930474 | MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways |
Q36061114 | Modulation of Wnt/β-catenin signaling pathway by bioactive food components |
Q46850333 | Molecular Approaches To Target GPCRs in Cancer Therapy. |
Q26798420 | Molecular classification of gastric cancer: Towards a pathway-driven targeted therapy |
Q28553543 | Monobenzyltin Complex C1 Induces Apoptosis in MCF-7 Breast Cancer Cells through the Intrinsic Signaling Pathway and through the Targeting of MCF-7-Derived Breast Cancer Stem Cells via the Wnt/β-Catenin Signaling Pathway |
Q34868613 | Multicentric and multifocal versus unifocal breast cancer: differences in the expression of E-cadherin suggest differences in tumor biology |
Q34795591 | Multiple drug resistance due to resistance to stem cells and stem cell treatment progress in cancer (Review). |
Q54329310 | NDRG2 is involved in the oncogenic properties of renal cell carcinoma and its loss is a novel independent poor prognostic factor after nephrectomy. |
Q38324456 | Nanocarrier-mediated drugs targeting cancer stem cells: an emerging delivery approach |
Q38127721 | Newly developed strategies for improving sensitivity to radiation by targeting signal pathways in cancer therapy |
Q64951391 | Next Viable Routes to Targeting Pancreatic Cancer Stemness: Learning from Clinical Setbacks. |
Q38448721 | Nonsteroidal anti-inflammatory drugs suppress cancer stem cells via inhibiting PTGS2 (cyclooxygenase 2) and NOTCH/HES1 and activating PPARG in colorectal cancer. |
Q47827202 | Novel Small Molecule Inhibitors of Cancer Stem Cell Signaling Pathways. |
Q38825765 | PKM2 promotes stemness of breast cancer cell by through Wnt/β-catenin pathway |
Q91560799 | Pan-cancer genomic amplifications underlie a WNT hyperactivation phenotype associated with stem cell-like features leading to poor prognosis |
Q38363276 | Personalized treatment for colorectal cancer: novel developments and putative therapeutic strategies |
Q46164259 | Pharmacologic Manipulation of Wnt Signaling and Cancer Stem Cells |
Q34429484 | Phenotypic screening in cancer drug discovery - past, present and future |
Q38390837 | Pluripotency transcription factors in the pathogenesis of colorectal cancer and implications for prognosis |
Q35907565 | Polyphyllin I induces cell cycle arrest and apoptosis in human myeloma cells via modulating β-catenin signaling pathway |
Q35685058 | Pre-clinical efficacy of combined therapy with novel β-catenin antagonist BC2059 and histone deacetylase inhibitor against AML cells |
Q36747742 | Preferential eradication of acute myelogenous leukemia stem cells by fenretinide |
Q37227295 | Prognostic value of wingless-type proteins in non-small cell lung cancer patients: a meta-analysis. |
Q26738491 | Promising Druggable Target in Head and Neck Squamous Cell Carcinoma: Wnt Signaling |
Q38632577 | Proteomic Approaches for Biomarker Panels in Cancer |
Q35807504 | Purinergic signaling in human pluripotent stem cells is regulated by the housekeeping gene encoding hypoxanthine guanine phosphoribosyltransferase |
Q58712209 | RIF1 promotes tumor growth and cancer stem cell-like traits in NSCLC by protein phosphatase 1-mediated activation of Wnt/β-catenin signaling |
Q37684607 | Reduced expression of FILIP1L, a novel WNT pathway inhibitor, is associated with poor survival, progression and chemoresistance in ovarian cancer. |
Q36972353 | Regulation of protumorigenic pathways by insulin like growth factor binding protein2 and its association along with β-catenin in breast cancer lymph node metastasis |
Q37376205 | Repurposing atovaquone: targeting mitochondrial complex III and OXPHOS to eradicate cancer stem cells |
Q35536672 | Repurposing the antipsychotic trifluoperazine as an antimetastasis agent |
Q48239444 | Resveratrol Protects SAMP8 Brain Under Metabolic Stress: Focus on Mitochondrial Function and Wnt Pathway |
Q37679979 | Role of Notch signaling pathway in pancreatic cancer |
Q91651955 | Role of Wnt/β-Catenin Signaling in the Chemoresistance Modulation of Colorectal Cancer |
Q37965633 | Role of canonical Wnt signaling in endometrial carcinogenesis |
Q35028775 | SIX2 Effects on Wilms Tumor Biology |
Q42404921 | SOX9 is a novel cancer stem cell marker surrogated by osteopontin in human hepatocellular carcinoma. |
Q38224211 | Safely targeting cancer stem cells via selective catenin coactivator antagonism |
Q50877576 | Sam68 Offers Selectively Aimed Modulation of Transcription in Cancer Stem Cells. |
Q38287048 | Secreted frizzled-related protein 4 and its implications in cancer and apoptosis. |
Q89537609 | Self-Renewal Signalling Pathway Inhibitors: Perspectives on Therapeutic Approaches for Cancer Stem Cells |
Q37907906 | Self-renewal related signaling in myeloid leukemia stem cells |
Q39016331 | Serine protease inhibitor Kazal type 1 promotes epithelial-mesenchymal transition through EGFR signaling pathway in prostate cancer |
Q91695602 | Shisa3 brakes resistance to EGFR-TKIs in lung adenocarcinoma by suppressing cancer stem cell properties |
Q26752554 | Signal Transduction Pathways of EMT Induced by TGF-β, SHH, and WNT and Their Crosstalks |
Q33827178 | Simultaneous overactivation of Wnt/β-catenin and TGFβ signalling by miR-128-3p confers chemoresistance-associated metastasis in NSCLC. |
Q38867041 | Small-molecule inhibition of CBP/catenin interactions eliminates drug-resistant clones in acute lymphoblastic leukemia |
Q36136205 | Stem cell quiescence |
Q38061726 | Stem cells and the skin |
Q34511615 | Stem memory T cells (TSCM)-their role in cancer and HIV immunotherapies |
Q92067206 | Sulforaphane Modulates Cell Migration and Expression of β-Catenin and Epithelial Mesenchymal Transition Markers in Breast Cancer Cells |
Q41143523 | Suppression of the Wnt signaling pathway may contribute to the inhibition of proliferation of human hepatocellular carcinoma SMMC-7721 cells by esculetin |
Q39009114 | Synergistic inhibition of HCC and liver cancer stem cell proliferation by targeting RAS/RAF/MAPK and WNT/β-catenin pathways |
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Q38767082 | Tankyrase 1 inhibitior XAV939 increases chemosensitivity in colon cancer cell lines via inhibition of the Wnt signaling pathway |
Q41912339 | Targeted molecular ablation of cancer stem cells for curing gastrointestinal cancers. |
Q33925257 | Targeting Hedgehog--a cancer stem cell pathway |
Q37763414 | Targeting Notch to target cancer stem cells. |
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Q37820099 | Targeting cancer stem cells by inhibiting Wnt, Notch, and Hedgehog pathways |
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Q42182917 | Targeting cancer stem cells: a new therapy to cure cancer patients. |
Q37975244 | Targeting embryonic signaling pathways in cancer therapy |
Q90568402 | Targeting glutaminase 1 attenuates stemness properties in hepatocellular carcinoma by increasing reactive oxygen species and suppressing Wnt/beta-catenin pathway |
Q26770039 | Targeting head and neck tumoral stem cells: From biological aspects to therapeutic perspectives |
Q26775961 | Targeting self-renewal pathways in cancer stem cells: clinical implications for cancer therapy |
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Q26801375 | The Impact of Hedgehog Signaling Pathway on DNA Repair Mechanisms in Human Cancer |
Q38645695 | The Implications and Future Perspectives of Nanomedicine for Cancer Stem Cell Targeted Therapies. |
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Q49804881 | The Role of Wnt Signal in Glioblastoma Development and Progression: A Possible New Pharmacological Target for the Therapy of This Tumor |
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