Secreted frizzled-related protein 4 and its implications in cancer and apoptosis.

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Secreted frizzled-related protein 4 and its implications in cancer and apoptosis. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1006439369
P356DOI10.1007/S13277-014-2956-Z
P698PubMed publication ID25501511

P50authorSebastian Other-Gee PohlQ63582693
P2093author name stringFrank Arfuso
Arun Dharmarajan
Vanathi Perumal
Ross Scott
P2860cites workDishevelled and Wnt signaling: is the nucleus the final frontier?Q21146756
Wnt signaling in development and diseaseQ21195871
Disulfide bond assignments of secreted Frizzled-related protein-1 provide insights about Frizzled homology and netrin modulesQ24292002
Expression of frizzled-related protein and Wnt-signalling molecules in invasive human breast tumoursQ24292176
Secreted frizzled-related protein 4 is silenced by hypermethylation and induces apoptosis in beta-catenin-deficient human mesothelioma cellsQ24294749
Differential effects of secreted frizzled-related proteins (sFRPs) on osteoblastic differentiation of mouse mesenchymal cells and apoptosis of osteoblastsQ24305287
Membranous expression of secreted frizzled-related protein 4 predicts for good prognosis in localized prostate cancer and inhibits PC3 cellular proliferation in vitroQ24307058
Up-regulation of human secreted frizzled homolog in apoptosis and its down-regulation in breast tumorsQ24309604
SARPs: a family of secreted apoptosis-related proteinsQ24311564
Secreted Frizzled related protein-4 (sFRP4) promotes epidermal differentiation and apoptosisQ24336317
Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue KineticsQ24564912
Wnt/beta-catenin signaling: components, mechanisms, and diseasesQ24630938
Wnt signal transduction pathwaysQ24641814
The WntsQ24802301
Both the caspase CSP-1 and a caspase-independent pathway promote programmed cell death in parallel to the canonical pathway for apoptosis in Caenorhabditis elegansQ27324230
Cell death: critical control pointsQ28240722
Frizzleds: new members of the superfamily of G-protein-coupled receptorsQ28246144
Wnt signaling: multiple pathways, multiple receptors, and multiple transcription factorsQ28247928
Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancerQ28251800
Expression of the secreted frizzled-related protein gene family is downregulated in human mesotheliomaQ28268844
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complexQ28283294
Combination analysis of hypermethylated Wnt-antagonist family genes as a novel epigenetic biomarker panel for bladder cancer detectionQ28306755
Expression and localization of secreted frizzled-related protein-4 in the rodent ovary: evidence for selective up-regulation in luteinized granulosa cellsQ28577888
Secreted frizzled-related protein 4 regulates two Wnt7a signaling pathways and inhibits proliferation in endometrial cancer cellsQ28578071
DDC-4, an apoptosis-associated gene, is a secreted frizzled relativeQ28579045
The Wnt/Ca2+ pathway: a new vertebrate Wnt signaling pathway takes shapeQ28613516
Caspases: enemies withinQ29547315
Secreted antagonists of the Wnt signalling pathwayQ29615521
Caught up in a Wnt storm: Wnt signaling in cancerQ29617494
Clearance of apoptotic cells: implications in health and diseaseQ30433781
Inverse correlation of secreted frizzled-related protein 4 and beta-catenin expression in endometrial stromal sarcomasQ33205850
Secreted frizzled-related protein 4: an angiogenesis inhibitor.Q33703825
Hypermethylation and expression regulation of secreted frizzled-related protein genes in colorectal tumorQ33867627
Expression of secreted frizzled related proteins 3 and 4 in human ventricular myocardium correlates with apoptosis related gene expressionQ33895331
An updated overview on Wnt signaling pathways: a prelude for moreQ34122601
A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancerQ34126908
Loss of secreted frizzled-related protein 4 correlates with an aggressive phenotype and predicts poor outcome in ovarian cancer patientsQ34171495
The activation of Akt/PKB signaling pathway and cell survival.Q34405519
Secreted frizzled-related protein 4 expression is positively associated with responsiveness to cisplatin of ovarian cancer cell lines in vitro and with lower tumour grade in mucinous ovarian cancersQ34435134
The developmental biology of Dishevelled: an enigmatic protein governing cell fate and cell polarityQ34455099
Expression of sFRP-4 and beta-catenin in human colorectal carcinomaQ34476841
Secreted frizzled-related protein 4 inhibits proliferation and metastatic potential in prostate cancerQ34625191
A first insight into the molecular mechanisms of apoptosisQ34649473
Secreted Frizzled-related proteins: searching for relationships and patternsQ34811402
Apoptosis and colorectal cancerQ35915905
Wnt and calcium signaling: beta-catenin-independent pathwaysQ36228742
Dishevelled activates Ca2+ flux, PKC, and CamKII in vertebrate embryos.Q36381456
WNT signaling in malignant mesothelioma.Q36486556
Secreted and transmembrane wnt inhibitors and activatorsQ36626700
SFRP-4 abrogates Wnt-3a-induced beta-catenin and Akt/PKB signalling and reverses a Wnt-3a-imposed inhibition of in vitro mammary differentiationQ36699327
Second hit in cervical carcinogenesis process: involvement of wnt/beta catenin pathwayQ36800769
Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and diseaseQ37102953
Epigenetics in bladder cancerQ37243940
Targeting Wnt signaling: can we safely eradicate cancer stem cells?Q37763415
Epigenetics of bladder cancerQ37987502
Secreted frizzled related proteins: Implications in cancersQ38169447
Frizzled-7 signalling controls tissue separation during Xenopus gastrulationQ38295420
Cancer stem-like cells from head and neck cancers are chemosensitized by the Wnt antagonist, sFRP4, by inducing apoptosis, decreasing stemness, drug resistance and epithelial to mesenchymal transitionQ38967885
Epigenetic regulation of the secreted frizzled-related protein family in human glioblastoma multiformeQ38982747
Low expression of secreted frizzled-related protein 4 in aggressive pituitary adenomaQ38985965
Wnt antagonist, secreted frizzled-related protein 4 (sFRP4), increases chemotherapeutic response of glioma stem-like cellsQ39036008
The role of the cysteine-rich domain and netrin-like domain of secreted frizzled-related protein 4 in angiogenesis inhibition in vitroQ39266254
Promoter methylation analysis of WNT/β-catenin signaling pathway regulators to detect adenocarcinoma or its precursor lesion of the cervix.Q39512938
Methylation analysis of SFRP genes family in cervical adenocarcinomaQ39972422
Hypermethylation and aberrant expression of secreted frizzled-related protein genes in pancreatic cancerQ39975021
Promoter methylation of SFRPs gene family in cervical cancerQ40024403
Frequent epigenetic inactivation of SFRP genes and constitutive activation of Wnt signaling in gastric cancerQ40171588
Role of DDC-4/sFRP-4, a secreted frizzled-related protein, at the onset of apoptosis in mammary involution.Q40650536
Apoptosis-associated gene expression in the corpus luteum of the rat.Q42674278
Aberrant promoter methylation of WIF-1 and SFRP1, 2, 4 genes in mesotheliomaQ42993323
The role of sFRP4, a secreted frizzled-related protein, in ovulationQ44483520
Aberrant methylation of secreted frizzled-related protein genes in esophageal adenocarcinoma and Barrett's esophagusQ46433748
Formation of the rupture site in preovulatory hamster and mouse follicles: loss of the surface epitheliumQ46643846
Wnt antagonist family genes as biomarkers for diagnosis, staging, and prognosis of renal cell carcinoma using tumor and serum DNA.Q46696080
Beta-catenin directly displaces Groucho/TLE repressors from Tcf/Lef in Wnt-mediated transcription activationQ46952924
Expression of secreted frizzled-related protein 4 (SFRP4) in primary serous ovarian tumoursQ47695854
Apoptosis in the rat mammary gland and ventral prostate: detection of cell death-associated genes using a coincident-expression cloning approachQ47956228
Hydroxytyrosol inhibits growth and cell proliferation and promotes high expression of sfrp4 in rat mammary tumours.Q51530435
Coincident expression of beta-catenin and cyclin D1 in endometrial stromal tumors and related high-grade sarcomas.Q54455510
An epigenetic marker panel for screening and prognostic prediction of ovarian cancer.Q54511422
Single nucleotide polymorphisms in Wnt signaling and cell death pathway genes and susceptibility to colorectal cancerQ57192209
Epigenetic Inactivation of SFRP Genes and TP53 Alteration Act Jointly as Markers of Invasive Bladder CancerQ59313166
Hypothesis: apoptosis may be a mechanism for the transition to heart failure with chronic pressure overloadQ72355233
Caspases: the proteases of the apoptotic pathwayQ77900358
SFRP4 was overexpressed in colorectal carcinomaQ84514483
P433issue1
P921main subjectapoptotic processQ14599311
P304page(s)143-152
P577publication date2014-12-13
P1433published inTumor BiologyQ15757842
P1476titleSecreted frizzled-related protein 4 and its implications in cancer and apoptosis
P478volume36

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cites work (P2860)
Q51687450Antagonizing canonical Wnt signaling pathway by recombinant human sFRP4 purified from E. coli and its implications in cancer therapy.
Q38974537Anti-cancer properties of olive oil secoiridoid phenols: a systematic review of in vivo studies.
Q38779589Anti-stromal treatment together with chemotherapy targets multiple signalling pathways in pancreatic adenocarcinoma
Q47353580Delivery of expression constructs of secreted frizzled-related protein 4 and its domains by chitosan-dextran sulfate nanoparticles enhances their expression and anti-cancer effects.
Q38972707Five years update on relationships between malignant pleural mesothelioma and exposure to asbestos and other elongated mineral particles
Q45723424SFRP4 gene expression is increased in aggressive prostate cancer
Q93023515Sfrp4 repression of the Ror2/Jnk cascade in osteoclasts protects cortical bone from excessive endosteal resorption
Q48114249Structure-based prediction of Wnt binding affinities for Frizzled-type cysteine-rich domains
Q37224290Systemic chromosome instability in Shugoshin-1 mice resulted in compromised glutathione pathway, activation of Wnt signaling and defects in immune system in the lung
Q37086242TIKI2 is upregulated and plays an oncogenic role in renal cell carcinoma
Q47553825The Role of Wnt Signalling in Angiogenesis
Q47392813U-CH17P, -M and -S, a new cell culture system for tumor diversity and progression in chordoma
Q92905497Wnt Binding Affinity Prediction for Putative Frizzled-Type Cysteine-Rich Domains

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