Systemic chromosome instability in Shugoshin-1 mice resulted in compromised glutathione pathway, activation of Wnt signaling and defects in immune system in the lung

scientific article published on 15 August 2016

Systemic chromosome instability in Shugoshin-1 mice resulted in compromised glutathione pathway, activation of Wnt signaling and defects in immune system in the lung is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/ONCSIS.2016.56
P932PMC publication ID5007830
P698PubMed publication ID27526110

P50authorWei DaiQ38320974
P2093author name stringY Zhang
C V Rao
G Kumar
E Rubin
H Y Yamada
S Lightfoot
P2860cites workShugoshin prevents dissociation of cohesin from centromeres during mitosis in vertebrate cellsQ21146367
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Vertebrate shugoshin links sister centromere cohesion and kinetochore microtubule stability in mitosisQ34344660
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Distinct MHC class I-dependent NK cell-activating receptors control cytomegalovirus infection in different mouse strainsQ34973765
R-spondin 3 regulates dorsoventral and anteroposterior patterning by antagonizing Wnt/β-catenin signaling in zebrafish embryosQ35185403
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Tumor-promoting/progressing role of additional chromosome instability in hepatic carcinogenesis in Sgo1 (Shugoshin 1) haploinsufficient miceQ35356022
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Antagonizing pathways leading to differential dynamics in colon carcinogenesis in Shugoshin1 (Sgo1)-haploinsufficient chromosome instability modelQ36059007
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Systemic Chromosome Instability Resulted in Colonic Transcriptomic Changes in Metabolic, Proliferation, and Stem Cell Regulators in Sgo1-/+ MiceQ36570842
Simultaneous targeting of 5-LOX-COX and ODC block NNK-induced lung adenoma progression to adenocarcinoma in A/J miceQ36958356
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SGOL1 variant B induces abnormal mitosis and resistance to taxane in non-small cell lung cancersQ37246242
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Calreticulin Expression in Human Non-Small Cell Lung Cancers Correlates with Increased Accumulation of Antitumor Immune Cells and Favorable PrognosisQ38796822
Ly49 family receptors are required for cancer immunosurveillance mediated by natural killer cells.Q38997851
Chromosome segregation errors as a cause of DNA damage and structural chromosome aberrationsQ39465329
Mad2-induced chromosome instability leads to lung tumour relapse after oncogene withdrawalQ39700353
Human Sgo1 downregulation leads to chromosomal instability in colorectal cancerQ39960114
Cigarette smoking impairs human pulmonary immunity to Mycobacterium tuberculosisQ41666071
Immunosurveillance against cancer-associated hyperploidy.Q43083269
Aneuploidy acts both oncogenically and as a tumor suppressorQ44738012
Chromosomal instability causes sensitivity to metabolic stress.Q46821301
The inner centromere-shugoshin network prevents chromosomal instability.Q52917865
Chromosomal instability detected by fluorescence in situ hybridization in surgical specimens of non-small cell lung cancer is associated with poor survivalQ73501601
Tobacco smoke-induced DNA damage and an early age of smoking initiation induce chromosome loss at 3p21 in lung cancerQ73521953
No evidence of microsatellite instability but frequent loss of heterozygosity in primary resected lung cancerQ73786123
Requirements for alpha d in IgG immune complex-induced rat lung injuryQ74463540
Immunodeficient mice have elevated numbers of NK cells in non-lymphoid tissuesQ79148116
A novel tumor-derived SGOL1 variant causes abnormal mitosis and unstable chromatid cohesionQ84007581
Cleavage of cohesin rings coordinates the separation of centrioles and chromatidsQ84533139
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
edgeRQ113334690
P433issue8
P921main subjectglutathioneQ116907
P304page(s)e256
P577publication date2016-08-15
P1433published inOncogenesisQ27724395
P1476titleSystemic chromosome instability in Shugoshin-1 mice resulted in compromised glutathione pathway, activation of Wnt signaling and defects in immune system in the lung
P478volume5