| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2011PLoSO...614789B |
| P356 | DOI | 10.1371/JOURNAL.PONE.0014789 |
| P932 | PMC publication ID | 3068133 |
| P698 | PubMed publication ID | 21479203 |
| P5875 | ResearchGate publication ID | 253001837 |
| P50 | author | Angela L. Tyner | Q40425349 |
| P2093 | author name string | Yu Zheng | |
| Donna M Peehl | |||
| Carmen Dominguez-Brauer | |||
| Mark D Evans | |||
| Patrick M Brauer | |||
| P2860 | cites work | Sik (BRK) phosphorylates Sam68 in the nucleus and negatively regulates its RNA binding ability | Q22254678 |
| Regulation of the nonreceptor tyrosine kinase Brk by autophosphorylation and by autoinhibition | Q24301621 | ||
| BRK phosphorylates PSF promoting its cytoplasmic localization and cell cycle arrest | Q24310412 | ||
| Regulated association of protein kinase B/Akt with breast tumor kinase | Q24314300 | ||
| Cloning and characterisation of cDNAs encoding a novel non-receptor tyrosine kinase, brk, expressed in human breast tumours | Q24314895 | ||
| Structural basis of the auto-inhibition mechanism of nonreceptor tyrosine kinase PTK6 | Q24319876 | ||
| Wnt/beta-catenin signaling: components, mechanisms, and diseases | Q24630938 | ||
| Functional interaction between beta-catenin and FOXO in oxidative stress signaling | Q28115106 | ||
| Protein tyrosine kinase 6 directly phosphorylates AKT and promotes AKT activation in response to epidermal growth factor | Q28115391 | ||
| BRK/Sik expression in the gastrointestinal tract and in colon tumors | Q28140957 | ||
| Altered localization and activity of the intracellular tyrosine kinase BRK/Sik in prostate tumor cells | Q28183216 | ||
| Brk, Srm, Frk, and Src42A Form a Distinct Family of Intracellular Src-Like Tyrosine Kinases | Q28202022 | ||
| Linking beta-catenin to androgen-signaling pathway | Q28215632 | ||
| Signal-dependent regulation of splicing via phosphorylation of Sam68 | Q28217232 | ||
| A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes | Q28256848 | ||
| Exon-intron structure of the human PTK6 gene demonstrates that PTK6 constitutes a distinct family of non-receptor tyrosine kinase | Q28283456 | ||
| Oncogenic functions of PTK6 are enhanced by its targeting to plasma membrane but abolished by its targeting to nucleus | Q39869787 | ||
| Crosstalk between the androgen receptor and beta-catenin in castrate-resistant prostate cancer | Q39910338 | ||
| Interaction of FOXO with beta-catenin inhibits beta-catenin/T cell factor activity | Q40016533 | ||
| The BRK tyrosine kinase is expressed in high-grade serous carcinoma of the ovary | Q40253367 | ||
| The intracellular tyrosine kinase Brk sensitizes non-transformed cells to inducers of apoptosis | Q40388197 | ||
| Beta-catenin is involved in insulin-like growth factor 1-mediated transactivation of the androgen receptor | Q40498605 | ||
| The nuclear tyrosine kinase BRK/Sik phosphorylates and inhibits the RNA-binding activities of the Sam68-like mammalian proteins SLM-1 and SLM-2. | Q40506613 | ||
| Characterisation and chromosome mapping of the human non receptor tyrosine kinase gene, brk. | Q41087231 | ||
| Establishment and characterization of an immortalized but non-transformed human prostate epithelial cell line: BPH-1. | Q41404265 | ||
| Binding of the polypyrimidine tract-binding protein-associated splicing factor (PSF) to the hepatitis delta virus RNA. | Q45412884 | ||
| Cross-talk between canonical Wnt signaling and the sirtuin-FoxO longevity pathway to protect against muscular pathology induced by mutant PABPN1 expression in C. elegans. | Q51912989 | ||
| BRK tyrosine kinase expression in a high proportion of human breast carcinomas | Q73615071 | ||
| Protein tyrosine kinase 6 negatively regulates growth and promotes enterocyte differentiation in the small intestine | Q28509681 | ||
| A second canon. Functions and mechanisms of beta-catenin-independent Wnt signaling | Q29619294 | ||
| Alternative splicing modulates autoinhibition and SH3 accessibility in the Src kinase Fyn. | Q30157097 | ||
| Molecular dissection of the interaction between the SH3 domain and the SH2-Kinase Linker region in PTK6. | Q30157778 | ||
| Interaction between Brk kinase and insulin receptor substrate-4. | Q30160247 | ||
| A novel intracellular epithelial cell tyrosine kinase is expressed in the skin and gastrointestinal tract | Q30193721 | ||
| Differential expression of the non-receptor tyrosine kinase BRK in oral squamous cell carcinoma and normal oral epithelium. | Q33208405 | ||
| Sam68-like mammalian protein 2, identified by digital differential display as expressed by podocytes, is induced in proteinuria and involved in splice site selection of vascular endothelial growth factor | Q33215312 | ||
| Breast tumor kinase (protein tyrosine kinase 6) regulates heregulin-induced activation of ERK5 and p38 MAP kinases in breast cancer cells | Q33283847 | ||
| PTK6 Regulates IGF-1-Induced Anchorage-Independent Survival | Q33644326 | ||
| Brk/PTK6 signaling in normal and cancer cell models | Q33690176 | ||
| Building a better understanding of the intracellular tyrosine kinase PTK6 - BRK by BRK | Q33912469 | ||
| Identification of beta-catenin as a target of the intracellular tyrosine kinase PTK6 | Q34195298 | ||
| Cytoplasmic retention of protein tyrosine kinase 6 promotes growth of prostate tumor cells | Q34659926 | ||
| Osteopontin promotes vascular endothelial growth factor-dependent breast tumor growth and angiogenesis via autocrine and paracrine mechanisms | Q34732748 | ||
| Wnt and beyond Wnt: multiple mechanisms control the transcriptional property of beta-catenin | Q34786597 | ||
| Expression and oncogenic role of Brk (PTK6/Sik) protein tyrosine kinase in lymphocytes. | Q35088231 | ||
| Insulin-like growth factor 1 regulates the location, stability, and transcriptional activity of beta-catenin | Q35382945 | ||
| Primary cell cultures as models of prostate cancer development | Q36078977 | ||
| Tyrosine kinase gene expression in the mouse small intestine. | Q36752745 | ||
| A role for the epithelial-cell-specific tyrosine kinase Sik during keratinocyte differentiation | Q36821163 | ||
| Gone with the Wnts: beta-catenin, T-cell factor, forkhead box O, and oxidative stress in age-dependent diseases of bone, lipid, and glucose metabolism | Q36876084 | ||
| A role for the GSG domain in localizing Sam68 to novel nuclear structures in cancer cell lines | Q36911484 | ||
| Osteopontin: regulation in tumor metastasis | Q37020157 | ||
| Wnt signaling and prostate cancer | Q37233002 | ||
| Brk protects breast cancer cells from autophagic cell death induced by loss of anchorage. | Q37316549 | ||
| ARF stimulates XPC to trigger nucleotide excision repair by regulating the repressor complex of E2F4. | Q37360067 | ||
| Induction of protein tyrosine kinase 6 in mouse intestinal crypt epithelial cells promotes DNA damage-induced apoptosis | Q37399415 | ||
| Osteopontin induces beta-catenin signaling through activation of Akt in prostate cancer cells | Q37455849 | ||
| Cross-regulation of signaling pathways: an example of nuclear hormone receptors and the canonical Wnt pathway | Q37688635 | ||
| Targeting Wnt signaling: can we safely eradicate cancer stem cells? | Q37763415 | ||
| Role of breast tumour kinase in the in vitro differentiation of HaCaT cells. | Q38441536 | ||
| Deregulation of the cell cycle by breast tumor kinase (Brk). | Q39738335 | ||
| Alternative splicing of the cyclin D1 proto-oncogene is regulated by the RNA-binding protein Sam68 | Q39760025 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | e14789 | |
| P577 | publication date | 2011-03-30 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | The alternative splice variant of protein tyrosine kinase 6 negatively regulates growth and enhances PTK6-mediated inhibition of β-catenin | |
| P478 | volume | 6 |
| Q28115769 | Brk/Protein tyrosine kinase 6 phosphorylates p27KIP1, regulating the activity of cyclin D-cyclin-dependent kinase 4 |
| Q30009178 | Cancer-Associated Mutations in Breast Tumor Kinase/PTK6 Differentially Affect Enzyme Activity and Substrate Recognition |
| Q38080556 | Context-specific protein tyrosine kinase 6 (PTK6) signalling in prostate cancer |
| Q37738575 | Cross-Species Genome-Wide Identification of Evolutionary Conserved MicroProteins |
| Q48539535 | Dual Inhibition of CDK4 and CDK2 via Targeting p27 Tyrosine Phosphorylation Induces a Potent and Durable Response in Breast Cancer Cells |
| Q34023653 | Evolution of breast cancer therapeutics: Breast tumour kinase's role in breast cancer and hope for breast tumour kinase targeted therapy |
| Q39125642 | PTK6 activation at the membrane regulates epithelial-mesenchymal transition in prostate cancer |
| Q34227580 | PTK6/BRK is expressed in the normal mammary gland and activated at the plasma membrane in breast tumors |
| Q90643576 | Protein tyrosine kinase 6 signaling in prostate cancer |
| Q28115210 | Protein-tyrosine kinase 6 promotes peripheral adhesion complex formation and cell migration by phosphorylating p130 CRK-associated substrate |
| Q41358979 | Signature of positive selection of PTK6 gene in East Asian populations: a cross talk for Helicobacter pylori invasion and gastric cancer endemicity |
| Q42357549 | Targeting protein tyrosine kinase 6 enhances apoptosis of colon cancer cells following DNA damage |
| Q37942610 | Wnt and SHH in prostate cancer: trouble mongers occupy the TRAIL towards apoptosis |
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