scholarly article | Q13442814 |
P2093 | author name string | Angela L Tyner | |
Wanian M Alwanian | |||
P2860 | cites work | Regulation of the nonreceptor tyrosine kinase Brk by autophosphorylation and by autoinhibition | Q24301621 |
A targetable GATA2-IGF2 axis confers aggressiveness in lethal prostate cancer | Q27853127 | ||
Protein-tyrosine kinase 6 promotes peripheral adhesion complex formation and cell migration by phosphorylating p130 CRK-associated substrate | Q28115210 | ||
Protein tyrosine kinase 6 directly phosphorylates AKT and promotes AKT activation in response to epidermal growth factor | Q28115391 | ||
Brk is coamplified with ErbB2 to promote proliferation in breast cancer | Q28115616 | ||
Brk/Protein tyrosine kinase 6 phosphorylates p27KIP1, regulating the activity of cyclin D-cyclin-dependent kinase 4 | Q28115769 | ||
Protein-tyrosine Phosphatase and Kinase Specificity in Regulation of SRC and Breast Tumor Kinase | Q28116384 | ||
Expression of the BRK tyrosine kinase in mammary epithelial cells enhances the coupling of EGF signalling to PI 3-kinase and Akt, via erbB3 phosphorylation | Q28140199 | ||
Altered localization and activity of the intracellular tyrosine kinase BRK/Sik in prostate tumor cells | Q28183216 | ||
Brk, Srm, Frk, and Src42A Form a Distinct Family of Intracellular Src-Like Tyrosine Kinases | Q28202022 | ||
Prostate cancer and the met hepatocyte growth factor receptor | Q28278555 | ||
Exon-intron structure of the human PTK6 gene demonstrates that PTK6 constitutes a distinct family of non-receptor tyrosine kinase | Q28283456 | ||
TNFα/IFNγ Mediated Intestinal Epithelial Barrier Dysfunction Is Attenuated by MicroRNA-93 Downregulation of PTK6 in Mouse Colonic Epithelial Cells | Q28551629 | ||
The mutational landscape of lethal castration-resistant prostate cancer | Q29614634 | ||
The alternative splice variant of protein tyrosine kinase 6 negatively regulates growth and enhances PTK6-mediated inhibition of β-catenin | Q30155592 | ||
A novel intracellular epithelial cell tyrosine kinase is expressed in the skin and gastrointestinal tract | Q30193721 | ||
Molecular alterations in primary prostate cancer after androgen ablation therapy | Q33224548 | ||
PTK6 Regulates IGF-1-Induced Anchorage-Independent Survival | Q33644326 | ||
Building a better understanding of the intracellular tyrosine kinase PTK6 - BRK by BRK | Q33912469 | ||
Copy number alteration burden predicts prostate cancer relapse | Q34002312 | ||
Mechanisms of HGF/Met signaling to Brk and Sam68 in breast cancer progression | Q34085432 | ||
Molecular genetics of prostate cancer: new prospects for old challenges | Q34127462 | ||
Cytoplasmic retention of protein tyrosine kinase 6 promotes growth of prostate tumor cells | Q34659926 | ||
The Molecular Taxonomy of Primary Prostate Cancer | Q34674332 | ||
Sphingosine-1-phosphate induces the migration of thyroid follicular carcinoma cells through the microRNA-17/PTK6/ERK1/2 pathway | Q35154495 | ||
Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth | Q35168294 | ||
PTK6 inhibition promotes apoptosis of Lapatinib-resistant Her2(+) breast cancer cells by inducing Bim. | Q35834635 | ||
Brk/PTK6 sustains activated EGFR signaling through inhibiting EGFR degradation and transactivating EGFR | Q35888553 | ||
Optimizing molecular signatures for predicting prostate cancer recurrence | Q36182273 | ||
Protein-tyrosine Phosphatase 1B Antagonized Signaling by Insulin-like Growth Factor-1 Receptor and Kinase BRK/PTK6 in Ovarian Cancer Cells* | Q37112768 | ||
Substantial interindividual and limited intraindividual genomic diversity among tumors from men with metastatic prostate cancer | Q37302524 | ||
Context-specific protein tyrosine kinase 6 (PTK6) signalling in prostate cancer | Q38080556 | ||
Commentary on "Integrative clinical genomics of advanced prostate cancer". Robinson D, Van Allen EM, Wu YM, Schultz N, Lonigro RJ, Mosquera JM, Montgomery B, Taplin ME, Pritchard CC, Attard G, Beltran H, Abida W, Bradley RK, Vinson J, Cao X, Vats P, | Q38370247 | ||
Molecular Updates in Prostate Cancer | Q38649868 | ||
HER2 and EGFR Overexpression Support Metastatic Progression of Prostate Cancer to Bone. | Q38735527 | ||
Targeting BRK-Positive Breast Cancers with Small-Molecule Kinase Inhibitors | Q38739711 | ||
MicroRNA-187, a downstream effector of TGFβ pathway, suppresses Smad-mediated epithelial-mesenchymal transition in colorectal cancer | Q38798884 | ||
RSK promotes prostate cancer progression in bone through ING3, CKAP2, and PTK6-mediated cell survival | Q38959778 | ||
PTK6 activation at the membrane regulates epithelial-mesenchymal transition in prostate cancer | Q39125642 | ||
Protein tyrosine kinase 6 protects cells from anoikis by directly phosphorylating focal adhesion kinase and activating AKT | Q39268132 | ||
Characterisation and chromosome mapping of the human non receptor tyrosine kinase gene, brk | Q41087231 | ||
Whole-genome and Transcriptome Sequencing of Prostate Cancer Identify New Genetic Alterations Driving Disease Progression | Q42691638 | ||
PTK6 regulates growth and survival of endocrine therapy-resistant ER+ breast cancer cells | Q45494068 | ||
PTEN is a protein phosphatase that targets active PTK6 and inhibits PTK6 oncogenic signaling in prostate cancer. | Q45904675 | ||
PTEN loss and activation of K-RAS and β-catenin cooperate to accelerate prostate tumourigenesis | Q47406034 | ||
EMT in cancer | Q47736873 | ||
PTEN Loss Promotes Intratumoral Androgen Synthesis and Tumor Microenvironment Remodeling via Aberrant Activation of RUNX2 in Castration-Resistant Prostate Cancer | Q49788391 | ||
Clinical implications of PTEN loss in prostate cancer | Q49818398 | ||
Deep Phosphotyrosine Proteomics by Optimization of Phosphotyrosine Enrichment and MS/MS Parameters | Q51156471 | ||
Gene expression alterations in prostate cancer predicting tumor aggression and preceding development of malignancy | Q51596197 | ||
The long tail of oncogenic drivers in prostate cancer. | Q52611753 | ||
Recent advances in prostate cancer research: large-scale genomic analyses reveal novel driver mutations and DNA repair defects | Q57108205 | ||
Genomic correlates of clinical outcome in advanced prostate cancer. | Q64912433 | ||
Taxol Induces Brk-dependent Prosurvival Phenotypes in TNBC Cells through an AhR/GR/HIF-driven Signaling Axis | Q89507021 | ||
MicroRNA-214 targets PTK6 to inhibit tumorigenic potential and increase drug sensitivity of prostate cancer cells | Q91665901 | ||
EMT and Cancer: More Than Meets the Eye | Q91823867 | ||
Loss of PTEN Expression Detected by Fluorescence Immunohistochemistry Predicts Lethal Prostate Cancer in Men Treated with Prostatectomy | Q92616203 | ||
Vemurafenib Inhibits Active PTK6 in PTEN-null Prostate Tumor Cells | Q92707257 | ||
P433 | issue | 1 | |
P304 | page(s) | 1-8 | |
P577 | publication date | 2020-02-25 | |
P13046 | publication type of scholarly work | review article | Q7318358 |
P1433 | published in | American journal of clinical and experimental urology | Q27725737 |
P1476 | title | Protein tyrosine kinase 6 signaling in prostate cancer | |
P478 | volume | 8 |
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