Prostate cancer and the met hepatocyte growth factor receptor

scientific article

Prostate cancer and the met hepatocyte growth factor receptor is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0065-230X(04)91002-0
P698PubMed publication ID15327888

P2093author name stringBeatrice S Knudsen
Magnus Edlund
P2860cites workA novel germ line juxtamembrane Met mutation in human gastric cancerQ40847293
Expression of membrane-type 1 matrix metalloproteinase (MT1-MMP) on prostate cancer cell linesQ40878257
Interleukin-6 induces prostate cancer cell growth accompanied by activation of stat3 signaling pathway .Q40905632
Prostate stromal cell-derived hepatocyte growth factor induces invasion of prostate cancer cell line DU145 through tumor-stromal interactionQ40923564
The anti-androgen hydroxyflutamide and androgens inhibit interleukin-6 production by an androgen-responsive human osteoblastic cell line.Q40934001
The alpha 6 beta 1 and alpha 6 beta 4 integrins in human prostate cancer progression.Q40939412
c-met proto-oncogene expression in benign and malignant human prostate tissuesQ40981774
Tyrosine Phosphorylation of Focal Adhesion Kinase Stimulated by Hepatocyte Growth Factor Leads to Mitogen-activated Protein Kinase ActivationQ41007034
Regulation of lnvasive Potential of Human Prostate Cancer Cell Lines by Hepatocyte Growth FactorQ41034938
Engineered mutants of HGF/SF with reduced binding to heparan sulphate proteoglycans, decreased clearance and enhanced activity in vivoQ41052630
Stromal cells from human benign prostate hyperplasia produce a growth-inhibitory factor for LNCaP prostate cancer cells, identified as interleukin-6.Q41159496
Interleukin-6: a candidate mediator of human prostate cancer morbidityQ41362792
Human leucocyte heparan sulphate proteoglycans and their roles in inflammationQ41370201
Identification of a cell-type-specific transcriptional repressor in the promoter region of the mouse hepatocyte growth factor geneQ41431686
Characterization of ALVA-41 cells, a new human prostatic cancer cell lineQ41440606
The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cellsQ41563732
Characterization of integrin subunits, cellular adhesion and tumorgenicity of four human prostate cell lines.Q41587684
Human primary prostate tumor cell line, ALVA‐31: A new model for studying the hormonal regulation of prostate tumor cell growthQ41587993
A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase.Q41615181
HGF induces FAK activation and integrin-mediated adhesion in MTLn3 breast carcinoma cellsQ41696277
The proto-oncogene c-Cbl is a positive regulator of Met-induced MAP kinase activation: a role for the adaptor protein Crk.Q41758116
Proliferative inflammatory atrophy of the prostate: implications for prostatic carcinogenesisQ41899984
Intermediate Cells in Human Prostate Epithelium Are Enriched in Proliferative Inflammatory AtrophyQ41977380
Inhibition of epithelial ductal branching in the prostate by sonic hedgehog is indirectly mediated by stromal cellsQ42438028
Intermediate basal cells of the prostate: in vitro and in vivo characterizationQ42439698
Keratin profiles in normal/hyperplastic prostates and prostate carcinomaQ42454819
Syndecan-1 expression in locally invasive and metastatic prostate cancerQ42457370
Basal cells are progenitors of luminal cells in primary cultures of differentiating human prostatic epitheliumQ42463087
Comparison of marker protein expression in benign prostatic hyperplasia in vivo and in vitroQ42484157
Demonstration of intermediate cells during human prostate epithelial differentiation in situ and in vitro using triple-staining confocal scanning microscopyQ42492179
Branching activity in the human prostate: a closer look at the structure of small glandular budsQ42500472
Cell differentiation lineage in the prostateQ42515180
Decreased levels of CD44 protein and mRNA in prostate carcinoma. Correlation with tumor grade and ploidyQ42524360
Diagnostic utility of immunohistochemical staining for p63, a sensitive marker of prostatic basal cellsQ42528668
Growth Factor–dependent Activation of αvβ3 Integrin in Normal Epithelial Cells: Implications for Tumor InvasionQ42796734
p63 is a prostate basal cell marker and is required for prostate developmentQ24290591
Sonic hedgehog activates mesenchymal Gli1 expression during prostate ductal bud formationQ24306433
Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene ProductQ24310794
A novel inducible transactivation domain in the androgen receptor: implications for PRK in prostate cancerQ24338270
Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptorsQ24339620
AKT-independent protection of prostate cancer cells from apoptosis mediated through complex formation between the androgen receptor and FKHR.Q24540534
Neutralizing monoclonal antibodies to hepatocyte growth factor/scatter factor (HGF/SF) display antitumor activity in animal modelsQ24629814
Akt suppresses androgen-induced apoptosis by phosphorylating and inhibiting androgen receptorQ24631156
Syndecan-1 expression has prognostic significance in head and neck carcinomaQ24650029
Interleukin-6- and cyclic AMP-mediated signaling potentiates neuroendocrine differentiation of LNCaP prostate tumor cells.Q24746259
Tumour-stromal interactions. Transforming growth factor-beta isoforms and hepatocyte growth factor/scatter factor in mammary gland ductal morphogenesisQ24801546
Crystal structure of the NK1 fragment of HGF/SF suggests a novel mode for growth factor dimerization and receptor bindingQ27766474
Purification and characterization of a complex containing matriptase and a Kunitz-type serine protease inhibitor from human milkQ28137768
Met receptor tyrosine kinase: enhanced signaling through adapter proteinsQ28140219
Cortisol inhibits hepatocyte growth factor/scatter factor expression and induces c-met transcripts in osteoblastsQ38314606
Transcriptional regulation of the hepatocyte growth factor (HGF) gene by the Sp family of transcription factorsQ38344823
Decreased expression of catenins (? and ?), p120 CTN, and E-cadherin cell adhesion proteins and E-cadherin gene promoter methylation in prostatic adenocarcinomasQ38458462
CD44 and CD44v6 downregulation in clinical prostatic carcinoma: relation to Gleason grade and cytoarchitecture.Q38472704
The transcriptional coactivator FHL2 transmits Rho signals from the cell membrane into the nucleusQ39646594
Regulation of scatter factor/hepatocyte growth factor responses by Ras, Rac, and Rho in MDCK cellsQ40021756
Scatter factor and the c-met receptor: a paradigm for mesenchymal/epithelial interactionQ40560399
Quantitative proteomic analysis of proteins released by neoplastic prostate epitheliumQ40598257
The chemokine KC regulates HGF-stimulated epithelial cell morphogenesisQ40619606
Effects of hepatocyte growth factor on urokinase-type plasminogen activator (uPA) and uPA receptor in DU145 prostate cancer cellsQ40646743
Androgen receptor expression is regulated by the phosphoinositide 3-kinase/Akt pathway in normal and tumoral epithelial cellsQ40736171
Intermediate cells in normal and malignant prostate epithelium express c-MET: implications for prostate cancer invasionQ40738685
A signaling adapter function for alpha6beta4 integrin in the control of HGF-dependent invasive growthQ40765252
Sustained activation of extracellular signal-regulated kinase stimulated by hepatocyte growth factor leads to integrin alpha 2 expression that is involved in cell scatteringQ40814942
Association of the HGF/SF receptor, c-met, with the cell-surface adhesion molecule, E-cadherin, and catenins in human tumor cellsQ28140678
Activation of hepatocyte growth factor and urokinase/plasminogen activator by matriptase, an epithelial membrane serine proteaseQ28144714
HGF/SF-met signaling in the control of branching morphogenesis and invasionQ28202466
Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming proteinQ28210330
Role of the hepatocyte growth factor receptor, c-Met, in oncogenesis and potential for therapeutic inhibitionQ28212407
Activation of the androgen receptor N-terminal domain by interleukin-6 via MAPK and STAT3 signal transduction pathwaysQ28212733
Ligand-independent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cellsQ28217019
Met, metastasis, motility and moreQ28235183
A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor familyQ28285975
Developmental roles of HGF/SF and its receptor, the c-Met tyrosine kinaseQ28286701
Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesisQ28295920
Normal and malignant prostate epithelial cells differ in their response to hepatocyte growth factor/scatter factorQ28345285
Scatter factor/hepatocyte growth factor is essential for liver developmentQ28504542
Prostate development requires Sonic hedgehog expressed by the urogenital sinus epitheliumQ28509263
Targeted disruption of the Nkx3.1 gene in mice results in morphogenetic defects of minor salivary glands: parallels to glandular duct morphogenesis in prostateQ28513101
Urokinase plasminogen activator amino-terminal peptides inhibit development of the rat ventral prostateQ28574557
Sonic hedgehog regulates prostatic growth and epithelial differentiationQ28580501
Phosphorylation-dependent paxillin-ERK association mediates hepatocyte growth factor-stimulated epithelial morphogenesisQ28587743
Evidence that insulin-like growth factor I and growth hormone are required for prostate gland developmentQ28592773
Androgen receptor phosphorylation. Regulation and identification of the phosphorylation sitesQ30309352
Androgen-repressed phenotype in human prostate cancerQ30454285
Suppression of androgen receptor transactivation by Pyk2 via interaction and phosphorylation of the ARA55 coregulatorQ30816464
The met proto-oncogene receptor and lumen formationQ30991648
The tyrosine phosphatase SHP-2 is required for sustained activation of extracellular signal-regulated kinase and epithelial morphogenesis downstream from the met receptor tyrosine kinaseQ33605698
Transforming growth factor-beta in benign and malignant prostateQ33645241
Unique expression pattern of the alpha6beta4 integrin and laminin-5 in human prostate carcinomaQ33667939
Roles of hepatocyte growth factor/scatter factor and transforming growth factor-beta1 in mammary gland ductal morphogenesisQ33923757
The roles of androgen receptors and androgen-binding proteins in nongenomic androgen actionsQ33961658
Enhanced transformation by a plasma membrane-associated met oncoprotein: activation of a phosphoinositide 3'-kinase-dependent autocrine loop involving hyaluronic acid and CD44.Q33963349
Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomasQ34053843
Interleukin-6 regulates androgen receptor activity and prostate cancer cell growthQ34158970
High expression of the Met receptor in prostate cancer metastasis to boneQ34163761
Morphogenesis of prostate cancerQ34243355
Isolation of a human prostate carcinoma cell line (DU 145)Q34255312
Mechanism of met oncogene activationQ42811433
Novel mutations of the MET proto-oncogene in papillary renal carcinomas.Q42815807
Characterization of the scatter factor/hepatocyte growth factor gene promoter. Positive and negative regulatory elements direct gene expression to mesenchymal cellsQ42830729
A switch from p130Cas/Crk to Gab1/Crk signaling correlates with anchorage independent growth and JNK activation in cells transformed by the Met receptor oncoproteinQ42832806
TGF-beta1 perturbs vascular development and inhibits epithelial differentiation in fetal lung in vivoQ43679029
Expression of E-cadherin in prostate cancer in formalin-fixed, paraffin-embedded tissues: correlation with pathological featuresQ44057337
Smooth muscle releases an epithelial cell scatter factor which binds to heparinQ44224038
The structural biology of growth factor receptor activationQ44368469
Prostate hyperplasia in a transgenic mouse with prostate-specific expression of prolactin.Q44440479
Possible mechanism of dexamethasone therapy for prostate cancer: Suppression of circulating level of interleukin‐6Q44441026
The HGF/SF antagonist NK4 reverses fibroblast- and HGF-induced prostate tumor growth and angiogenesis in vivo.Q44503111
Orchiectomy Increases Bone Marrow Interleukin-6 Levels in MiceQ45110162
Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomasQ45345804
Molecular cloning of a new transforming gene from a chemically transformed human cell line.Q45345810
CWR22 xenograft as an ex vivo human tumor model for prostate cancer gene therapyQ45876484
Regulation of migration of primary prostate epithelial cells by secreted factors from prostate stromal cellsQ47694776
Epidermal growth factor (EGF)- and scatter factor/hepatocyte growth factor (SF/HGF)-mediated keratinocyte migration is coincident with induction of matrix metalloproteinase (MMP)-9Q47903225
Role of morphogenetic factors in metastasis of mammary carcinoma cellsQ52996861
The five amino acid-deleted isoform of hepatocyte growth factor promotes carcinogenesis in transgenic miceQ53426264
E-cadherin expression in prostate cancer: a broad survey using high-density tissue microarray technologyQ53999986
Abnormal E-cadherin expression and prostate cell blood dissemination as markers of biological recurrence in cancerQ57782605
Cell surface proteoglycan syndecan-1 mediates hepatocyte growth factor binding and promotes Met signaling in multiple myelomaQ58324023
Heparan Sulfate-modified CD44 Promotes Hepatocyte Growth Factor/Scatter Factor-induced Signal Transduction through the Receptor Tyrosine Kinase c-MetQ58324027
Cortisol Decreases Hepatocyte Growth Factor Levels in Human Osteoblast-Like CellsQ61480386
Osteopontin-induced, integrin-dependent migration of human mammary epithelial cells involves activation of the hepatocyte growth factor receptor (Met)Q62496773
Morphogenesis of prostatic carcinomaQ70061158
Testosterone, dihydrotestosterone and androstanediols in plasma, testes and prostates of rats during developmentQ71460002
Altered expression of CD44 in human prostate cancer during progressionQ71802064
HGF-induced tubulogenesis and branching of epithelial cells is modulated by extracellular matrix and TGF-betaQ72638374
Interleukin-6 induces proliferation of rat hepatocytes in vivoQ73011056
The effects of growth factors associated with osteoblasts on prostate carcinoma proliferation and chemotaxis: implications for the development of metastatic diseaseQ73106884
Tissue microarray analysis reveals prognostic significance of syndecan-1 expression in prostate cancerQ73135517
Prognostic value of CD44 standard, variant isoforms 3 and 6 and -catenin expression in local prostate cancer treated by radical prostatectomyQ73236066
Primary prostatic epithelial cell binding to human bone marrow stroma and the role of alpha2beta1 integrinQ73394978
Expression of syndecan-1 is common in human lung cancers independent of expression of epidermal growth factor receptorQ73411359
Heparan sulfate proteoglycan expression in human lung-cancer cellsQ73507963
Involvement of focal adhesion kinase in hepatocyte growth factor-induced scatter of Madin-Darby canine kidney cellsQ73538283
Somatic mutations of the MET oncogene are selected during metastatic spread of human HNSC carcinomasQ73586595
Prostatic ductal system in rats: Tissue-specific expression and regional variation in stromal distribution of transforming growth factor-β1Q73690899
Radioimmunoscintigraphy of tumors autocrine for human met and hepatocyte growth factor/scatter factorQ73814020
Reduced expression of syndecan-1 in human hepatocellular carcinoma with high metastatic potentialQ73841954
Substrate specificity of alpha(v)beta(3) integrin-mediated cell migration and phosphatidylinositol 3-kinase/AKT pathway activationQ73843666
High syndecan-1 expression is associated with favourable outcome in squamous cell lung carcinoma treated with radical surgeryQ73965564
HGF/scatter factor selectively promotes cell invasion by increasing integrin avidityQ74121592
E-cadherin expression as a marker of tumor aggressiveness in routinely processed radical prostatectomy specimensQ77304979
Hepatocyte growth factor induces tubulogenesis of primary renal proximal tubular epithelial cellsQ77853079
Androgens modulate interleukin-6 production by gingival fibroblasts in vitroQ77974127
Progression-linked overexpression of c-Met in prostatic intraepithelial neoplasia and latent as well as clinical prostate cancersQ78148740
Circulating levels of interleukin-6 in patients with hormone refractory prostate cancerQ78225972
Derivation of androgen-independent human LNCaP prostatic cancer cell sublines: role of bone stromal cellsQ34340236
Progression of metastatic human prostate cancer to androgen independence in immunodeficient SCID miceQ34420980
Efficient Cellular Transformation by the Met Oncoprotein Requires a Functional Grb2 Binding Site and Correlates with Phosphorylation of the Grb2-associated Proteins, Cbl and Gab1Q34434226
Association of the Multisubstrate Docking Protein Gab1 with the Hepatocyte Growth Factor Receptor Requires a Functional Grb2 Binding Site Involving Tyrosine 1356Q34434985
Activation of cdc42, rac, PAK, and rho-kinase in response to hepatocyte growth factor differentially regulates epithelial cell colony spreading and dissociationQ34712138
Cbl-transforming variants trigger a cascade of molecular alterations that lead to epithelial mesenchymal conversionQ34764852
Different phenotypes in human prostate cancer: alpha6 or alpha3 integrin in cell-extracellular adhesion sitesQ34929028
Grappling with metastatic risk: bringing molecular imaging of Met expression toward clinical use.Q35054675
The "Gab" in signal transduction.Q35082143
Hormonal, cellular, and molecular control of prostatic developmentQ35088639
Roles of hepatocyte growth factor (HGF) activator and HGF activator inhibitor in the pericellular activation of HGF/scatter factorQ35144580
How to make tubes: signaling by the Met receptor tyrosine kinaseQ35147372
Hepatocyte growth factor prevents acute renal failure and accelerates renal regeneration in miceQ35229384
Invasiveness and metastasis of NIH 3T3 cells induced by Met-hepatocyte growth factor/scatter factor autocrine stimulationQ35277738
Hsp90 as a therapeutic target in prostate cancerQ35565240
Prolactin receptor expression in the developing human prostate and in hyperplastic, dysplastic, and neoplastic lesionsQ35786210
Hepatocyte growth factor secreted by prostate-derived stromal cells stimulates growth of androgen-independent human prostatic carcinoma cellsQ35829375
Expression of c-Met and heparan-sulfate proteoglycan forms of CD44 in colorectal cancerQ35829554
Association between syndecan-1 expression and clinical outcome in squamous cell carcinoma of the head and neckQ36080017
Scatter factor: molecular characteristics and effect on the invasiveness of epithelial cellsQ36223889
Roles of hepatocyte growth factor/scatter factor and the met receptor in the early development of the metanephrosQ36235129
Hepatocyte growth factor/scatter factor induces a variety of tissue-specific morphogenic programs in epithelial cellsQ36236279
Motogenic and morphogenic activity of epithelial receptor tyrosine kinasesQ36236949
EphA kinase activation regulates HGF-induced epithelial branching morphogenesisQ36325486
Activation of the Met receptor by cell attachment induces and sustains hepatocellular carcinomas in transgenic miceQ36326357
Enhanced tumorigenicity and invasion-metastasis by hepatocyte growth factor/scatter factor-met signalling in human cells concomitant with induction of the urokinase proteolysis networkQ36557528
A Novel Transcriptional Regulatory Region within the Core Promoter of the Hepatocyte Growth Factor Gene Is Responsible for Its Inducibility by Cytokines via the C/EBP Family of Transcription FactorsQ36572989
Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factorQ36705281
The mutationally activated Met receptor mediates motility and metastasisQ36735738
Overexpression of a kinase-deficient transforming growth factor-beta type II receptor in mouse mammary stroma results in increased epithelial branchingQ36851915
Pharmacologic shifting of a balance between protein refolding and degradation mediated by Hsp90Q37044062
Cellular adherence elicits ligand-independent activation of the Met cell-surface receptorQ37404891
Etiology and disease process of benign prostatic hyperplasiaQ38211704
Sulfated oligosaccharides promote hepatocyte growth factor association and govern its mitogenic activityQ38293448
P407language of work or nameEnglishQ1860
P921main subjectprostate cancerQ181257
P304page(s)31-67
P577publication date2004-01-01
P13046publication type of scholarly workreview articleQ7318358
P1433published inAdvances in Cancer ResearchQ3113522
P1476titleProstate cancer and the met hepatocyte growth factor receptor
P478volume91

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cites work (P2860)
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