Interleukin-6- and cyclic AMP-mediated signaling potentiates neuroendocrine differentiation of LNCaP prostate tumor cells.

scientific article

Interleukin-6- and cyclic AMP-mediated signaling potentiates neuroendocrine differentiation of LNCaP prostate tumor cells. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/MCB.21.24.8471-8482.2001
P3181OpenCitations bibliographic resource ID3532751
P932PMC publication ID100010
P698PubMed publication ID11713282

P50authorDaniel J MurphyQ47112024
P2093author name stringS J Parsons
M E Cox
P D Deeble
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Etk/Bmx, a tyrosine kinase with a pleckstrin-homology domain, is an effector of phosphatidylinositol 3'-kinase and is involved in interleukin 6-induced neuroendocrine differentiation of prostate cancer cellsQ24319902
Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTORQ28144113
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c-Raf-mediated inhibition of epidermal growth factor-stimulated cell migrationQ30304264
Activated 3',5'-cyclic AMP-dependent protein kinase is sufficient to induce neuroendocrine-like differentiation of the LNCaP prostate tumor cell lineQ30305599
A 42-kD tyrosine kinase substrate linked to chromaffin cell secretion exhibits an associated MAP kinase activity and is highly related to a 42-kD mitogen-stimulated protein in fibroblastsQ30441235
Induction of c-fos mRNA and AP-1 DNA-binding activity by cAMP in cooperation with either the adenovirus 243- or the adenovirus 289-amino acid E1A proteinQ30454143
Cathepsin D and chromogranin A as predictors of long term disease specific survival after radical prostatectomy for localized carcinoma of the prostateQ30471390
Elevation of cyclic adenosine 3',5'-monophosphate potentiates activation of mitogen-activated protein kinase by growth factors in LNCaP prostate cancer cellsQ30473045
Androgen-independent cancer progression and bone metastasis in the LNCaP model of human prostate cancerQ34340156
Neurotensin is an autocrine trophic factor stimulated by androgen withdrawal in human prostate cancerQ35264411
Interleukin-6 and its receptor: a paradigm for cytokinesQ35425050
Terminal neuroendocrine differentiation of human prostate carcinoma cells in response to increased intracellular cyclic AMPQ35436566
Interleukin-6: structure-function relationships.Q36280356
Multiple sequence elements of a single functional class are required for cyclic AMP responsiveness of the mouse c-fos promoterQ36762038
Elevated levels of circulating interleukin-6 and transforming growth factor-beta1 in patients with metastatic prostatic carcinomaQ39487932
Immunophilin ligands and GDNF enhance neurite branching or elongation from developing dopamine neurons in cultureQ40870361
Interleukin-6 induces prostate cancer cell growth accompanied by activation of stat3 signaling pathway .Q40905632
STAT3 mediates IL-6-induced neuroendocrine differentiation in prostate cancer cells .Q40905638
STAT3 mediates IL-6-induced growth inhibition in the human prostate cancer cell line LNCaP.Q40908937
Transdifferentiation of prostate cancer cells to a neuroendocrine cell phenotype in vitro and in vivoQ40922547
Modulation of neuroendocrine differentiation in prostate cancer by interleukin-1 and -2.Q41019559
The cyclic adenosine monophosphate-dependent protein kinase (PKA) is required for the sustained activation of mitogen-activated kinases and gene expression by nerve growth factorQ41045775
Neurotensin receptor expression in prostate cancer cell line and growth effect of NT at physiological concentrationsQ41110192
Transcriptional regulation of neuronal nicotinic acetylcholine receptor genes. Functional interactions between Sp1 and the rat beta4 subunit gene promoterQ41144513
Stromal cells from human benign prostate hyperplasia produce a growth-inhibitory factor for LNCaP prostate cancer cells, identified as interleukin-6.Q41159496
Interleukin-6: a candidate mediator of human prostate cancer morbidityQ41362792
Parathyroid hormone-related protein: a potential autocrine growth regulator in human prostate cancer cell linesQ41469811
Interleukin 6 receptor mRNA in prostate carcinomas and benign prostate hyperplasia.Q41472510
Interleukin 6 and its receptor: ten years laterQ41722189
Integration of growth factor signals at the c-fos serum response elementQ42813969
P433issue24
P407language of work or nameEnglishQ1860
P921main subjectcell biologyQ7141
interleukinsQ194908
prostate neoplasmQ56014511
P304page(s)8471-8482
P577publication date2001-12-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleInterleukin-6- and cyclic AMP-mediated signaling potentiates neuroendocrine differentiation of LNCaP prostate tumor cells
P478volume21

Reverse relations

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