scholarly article | Q13442814 |
P50 | author | Daniel J Murphy | Q47112024 |
P2093 | author name string | S J Parsons | |
M E Cox | |||
P D Deeble | |||
P2860 | cites work | Effects of serotonin on neurite outgrowth from thalamic neurons in vitro | Q48226550 |
Bone morphogenetic protein-2 promotes dissociated effects on the number and differentiation of cultured ventral mesencephalic dopaminergic neurons | Q48281735 | ||
Class III beta-tubulin isotype (beta III) in the adrenal medulla: I. Localization in the developing human adrenal medulla. | Q52189573 | ||
Sp1 and Sp3 regulate expression of the neuronal nicotinic acetylcholine receptor beta4 subunit gene. | Q52559253 | ||
Relation of endocrine-paracrine cells to cell proliferation in normal, hyperplastic, and neoplastic human prostate | Q67701823 | ||
A common nuclear signal transduction pathway activated by growth factor and cytokine receptors | Q70476706 | ||
Endocrine-paracrine cell types in the prostate and prostatic adenocarcinoma are postmitotic cells | Q71674458 | ||
Nicotine stimulates secretion of both catecholamines and acetylcholinesterase from cultured adrenal chromaffin cells | Q71690022 | ||
Enhanced expression of parathyroid hormone-related protein in prostate cancer as compared with benign prostatic hyperplasia | Q71869756 | ||
Interleukin-6 as a paracrine and autocrine growth factor in human prostatic carcinoma cells in vitro | Q71955600 | ||
Class III beta-tubulin isotype (beta III) in the adrenal medulla: II. Localization in primary human pheochromocytomas | Q74364440 | ||
Class III beta-tubulin isotype (beta III) in the adrenal medulla: III. Differential expression of neuronal and glial antigens identifies two distinct populations of neuronal and glial-like (sustentacular) cells in the PC12 rat pheochromocytoma cell | Q74364445 | ||
Circulating levels of interleukin-6 in patients with hormone refractory prostate cancer | Q78225972 | ||
Transdifferentiation of cultured human prostate cancer cells to a neuroendocrine cell phenotype in a hormone-depleted medium | Q83177003 | ||
Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP | Q22008544 | ||
Requirement of ErbB2 for signalling by interleukin-6 in prostate carcinoma cells | Q24317507 | ||
Etk/Bmx, a tyrosine kinase with a pleckstrin-homology domain, is an effector of phosphatidylinositol 3'-kinase and is involved in interleukin 6-induced neuroendocrine differentiation of prostate cancer cells | Q24319902 | ||
Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR | Q28144113 | ||
Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation | Q28288257 | ||
Effect of phosphorylation on activities of Rap1A to interact with Raf-1 and to suppress Ras-dependent Raf-1 activation | Q28292424 | ||
cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway | Q28611450 | ||
Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells | Q29618480 | ||
Acquisition of neuroendocrine characteristics by prostate tumor cells is reversible: implications for prostate cancer progression | Q30304209 | ||
c-Raf-mediated inhibition of epidermal growth factor-stimulated cell migration | Q30304264 | ||
Activated 3',5'-cyclic AMP-dependent protein kinase is sufficient to induce neuroendocrine-like differentiation of the LNCaP prostate tumor cell line | Q30305599 | ||
A 42-kD tyrosine kinase substrate linked to chromaffin cell secretion exhibits an associated MAP kinase activity and is highly related to a 42-kD mitogen-stimulated protein in fibroblasts | Q30441235 | ||
Induction of c-fos mRNA and AP-1 DNA-binding activity by cAMP in cooperation with either the adenovirus 243- or the adenovirus 289-amino acid E1A protein | Q30454143 | ||
Cathepsin D and chromogranin A as predictors of long term disease specific survival after radical prostatectomy for localized carcinoma of the prostate | Q30471390 | ||
Elevation of cyclic adenosine 3',5'-monophosphate potentiates activation of mitogen-activated protein kinase by growth factors in LNCaP prostate cancer cells | Q30473045 | ||
Androgen-independent cancer progression and bone metastasis in the LNCaP model of human prostate cancer | Q34340156 | ||
Neurotensin is an autocrine trophic factor stimulated by androgen withdrawal in human prostate cancer | Q35264411 | ||
Interleukin-6 and its receptor: a paradigm for cytokines | Q35425050 | ||
Terminal neuroendocrine differentiation of human prostate carcinoma cells in response to increased intracellular cyclic AMP | Q35436566 | ||
Interleukin-6: structure-function relationships. | Q36280356 | ||
Multiple sequence elements of a single functional class are required for cyclic AMP responsiveness of the mouse c-fos promoter | Q36762038 | ||
Elevated levels of circulating interleukin-6 and transforming growth factor-beta1 in patients with metastatic prostatic carcinoma | Q39487932 | ||
Immunophilin ligands and GDNF enhance neurite branching or elongation from developing dopamine neurons in culture | Q40870361 | ||
Interleukin-6 induces prostate cancer cell growth accompanied by activation of stat3 signaling pathway . | Q40905632 | ||
STAT3 mediates IL-6-induced neuroendocrine differentiation in prostate cancer cells . | Q40905638 | ||
STAT3 mediates IL-6-induced growth inhibition in the human prostate cancer cell line LNCaP. | Q40908937 | ||
Transdifferentiation of prostate cancer cells to a neuroendocrine cell phenotype in vitro and in vivo | Q40922547 | ||
Modulation of neuroendocrine differentiation in prostate cancer by interleukin-1 and -2. | Q41019559 | ||
The cyclic adenosine monophosphate-dependent protein kinase (PKA) is required for the sustained activation of mitogen-activated kinases and gene expression by nerve growth factor | Q41045775 | ||
Neurotensin receptor expression in prostate cancer cell line and growth effect of NT at physiological concentrations | Q41110192 | ||
Transcriptional regulation of neuronal nicotinic acetylcholine receptor genes. Functional interactions between Sp1 and the rat beta4 subunit gene promoter | Q41144513 | ||
Stromal cells from human benign prostate hyperplasia produce a growth-inhibitory factor for LNCaP prostate cancer cells, identified as interleukin-6. | Q41159496 | ||
Interleukin-6: a candidate mediator of human prostate cancer morbidity | Q41362792 | ||
Parathyroid hormone-related protein: a potential autocrine growth regulator in human prostate cancer cell lines | Q41469811 | ||
Interleukin 6 receptor mRNA in prostate carcinomas and benign prostate hyperplasia. | Q41472510 | ||
Interleukin 6 and its receptor: ten years later | Q41722189 | ||
Integration of growth factor signals at the c-fos serum response element | Q42813969 | ||
P433 | issue | 24 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | cell biology | Q7141 |
interleukins | Q194908 | ||
prostate neoplasm | Q56014511 | ||
P304 | page(s) | 8471-8482 | |
P577 | publication date | 2001-12-01 | |
P1433 | published in | Molecular and Cellular Biology | Q3319478 |
P1476 | title | Interleukin-6- and cyclic AMP-mediated signaling potentiates neuroendocrine differentiation of LNCaP prostate tumor cells | |
P478 | volume | 21 |
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