| scholarly article | Q13442814 |
| P2093 | author name string | H. Yao | |
| M. G. Pan | |||
| R. D. York | |||
| P. J. Stork | |||
| C. S. Rim | |||
| M. R. Vossler | |||
| P2860 | cites work | JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain | Q24308838 |
| Ras/Rap effector specificity determined by charge reversal | Q24315941 | ||
| Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G | Q24651040 | ||
| Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation | Q28131755 | ||
| A divergence in the MAP kinase regulatory network defined by MEK kinase and Raf | Q28263195 | ||
| A novel mitogen-activated protein kinase phosphatase. Structure, expression, and regulation | Q28582955 | ||
| Association of MEK1 with p21ras.GMPPNP is dependent on B-Raf | Q28583306 | ||
| Purification of a Ras-dependent mitogen-activated protein kinase kinase kinase from bovine brain cytosol and its identification as a complex of B-Raf and 14-3-3 proteins | Q28609134 | ||
| RapV12 antagonizes Ras-dependent activation of ERK1 and ERK2 by LPA and EGF in Rat-1 fibroblasts | Q28646356 | ||
| Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane | Q29618478 | ||
| Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells | Q29618480 | ||
| The SRF accessory protein Elk-1 contains a growth factor-regulated transcriptional activation domain | Q29620270 | ||
| Biochemical Analysis of MEK Activation in NIH3T3 Fibroblasts | Q30054277 | ||
| Inhibition of the EGF-Activated MAP Kinase Signaling Pathway by Adenosine 3′,5′-Monophosphate | Q30464735 | ||
| Microinjection of smg/rap1/Krev-1 p21 into Swiss 3T3 Cells Induces DNA Synthesis and Morphological Changes | Q30790112 | ||
| Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro | Q33292215 | ||
| Genetic analysis of the Kirsten-ras-revertant 1 gene: potentiation of its tumor suppressor activity by specific point mutations | Q33615357 | ||
| Differential effects on cAMP on the MAP kinase cascade: evidence for a cAMP-insensitive step that can bypass Raf-1 | Q34450770 | ||
| Synergistic effects of cyclic AMP and nerve growth factor on neurite outgrowth and microtubule stability of PC12 cells | Q36211944 | ||
| Differential regulation of Raf-1 and B-Raf and Ras-dependent activation of mitogen-activated protein kinase by cyclic AMP in PC12 cells | Q36555259 | ||
| B-Raf-dependent regulation of the MEK-1/mitogen-activated protein kinase pathway in PC12 cells and regulation by cyclic AMP. | Q36666870 | ||
| The mouse B-raf gene encodes multiple protein isoforms with tissue-specific expression. | Q36681724 | ||
| Phosphorylation of a Ras-related GTP-binding protein, Rap-1b, by a neuronal Ca2+/calmodulin-dependent protein kinase, CaM kinase Gr. | Q37456088 | ||
| Regulation of Ras-mediated signalling: more than one way to skin a cat. | Q40605447 | ||
| Regulation of epidermal growth factor receptor signaling by phosphorylation of the ras exchange factor hSOS1. | Q41217316 | ||
| Post-translational modification of H-Ras is required for activation of, but not for association with, B-Raf | Q41224854 | ||
| Activation of brain B-Raf protein kinase by Rap1B small GTP-binding protein | Q41238096 | ||
| Cyclic Adenosine Monophosphate Can Convert Epidermal Growth Factor into a Differentiating Factor in Neuronal Cells | Q41302019 | ||
| Inhibition by cAMP of Ras-Dependent Activation of Raf | Q41514458 | ||
| Dominant inhibitory Ras mutants selectively inhibit the activity of either cellular or oncogenic Ras. | Q41670354 | ||
| Cyclic AMP-dependent activation of Rap1b | Q42827715 | ||
| Determination of v-Mos-catalyzed phosphorylation sites and autophosphorylation sites on MAP kinase kinase by ESI/MS. | Q42829810 | ||
| Inhibition of GTPase activating protein stimulation of Ras-p21 GTPase by the Krev-1 gene product | Q44794826 | ||
| Nerve Growth Factor-mediated Activation of the Mitogen-activated Protein (MAP) Kinase Cascade Involves a Signaling Complex Containing B-Raf and HSP90 | Q57711702 | ||
| Different effects of various phospholipids on Ki-Ras-, Ha-Ras-, and Rap1B-induced B-Raf activation | Q71143479 | ||
| Differentiation of PC12 cells in response to a cAMP analogue is accompanied by sustained activation of mitogen-activated protein kinase. Comparison with the effects of insulin, growth factors and phorbol esters | Q72771043 | ||
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 73–82 | |
| P577 | publication date | 1997-04-04 | |
| P1433 | published in | Cell | Q655814 |
| P1476 | title | cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway | |
| P478 | volume | 89 |
| Q31881906 | 5-HT(7) receptors activate the mitogen activated protein kinase extracellular signal related kinase in cultured rat hippocampal neurons |
| Q36641041 | 8-Cl-cAMP antagonizes mitogen-activated protein kinase activation and cell growth stimulation induced by epidermal growth factor. |
| Q42828386 | 8-Cl-cAMP induces cell cycle-specific apoptosis in human cancer cells |
| Q28211197 | A CalDAG-GEFI/Rap1/B-Raf cassette couples M(1) muscarinic acetylcholine receptors to the activation of ERK1/2 |
| Q34463200 | A Ral guanine exchange factor-Ral pathway is conserved in Drosophila melanogaster and sheds new light on the connectivity of the Ral, Ras, and Rap pathways |
| Q22004019 | A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia |
| Q40163505 | A Wnt-CKIvarepsilon-Rap1 pathway regulates gastrulation by modulating SIPA1L1, a Rap GTPase activating protein. |
| Q40619306 | A cAMP-activated pathway, including PKA and PI3K, regulates neuronal differentiation. |
| Q34301408 | A cAMP-dependent, protein kinase A-independent signaling pathway mediating neuritogenesis through Egr1 in PC12 cells |
| Q40177748 | A chemical biology approach identifies a beta-2 adrenergic receptor agonist that causes human tumor regression by blocking the Raf-1/Mek-1/Erk1/2 pathway |
| Q36591332 | A critical role of Rap1b in B-cell trafficking and marginal zone B-cell development. |
| Q22008551 | A family of cAMP-binding proteins that directly activate Rap1 |
| Q35556102 | A glance at adenosine receptors: novel target for antitumor therapy |
| Q41518918 | A kinase to remember: dual roles for MAP kinase in long-term memory |
| Q34610725 | A misexpression screen identifies genes that can modulate RAS1 pathway signaling in Drosophila melanogaster |
| Q36223595 | A mutation in CLOCK leads to altered dopamine receptor function |
| Q34156405 | A novel Epac-specific cAMP analogue demonstrates independent regulation of Rap1 and ERK. |
| Q22010940 | A novel regulatory mechanism of MAP kinases activation and nuclear translocation mediated by PKA and the PTP-SL tyrosine phosphatase |
| Q36739904 | A novel role for Cdk1/cyclin B in regulating B-raf activation at mitosis |
| Q48337718 | A potential role of Ras-mediated signal transduction for the enhancement of depolarization-induced Ca2+ responses in hippocampal neurons by basic fibroblast growth factor |
| Q39654783 | A trifluoromethyl analog of verbenachalcone promotes neurite outgrowth and cell proliferation of NeuroScreen-1 cells |
| Q24564162 | A unique pathway for sustained neurotrophin signaling through an ankyrin-rich membrane-spanning protein |
| Q41959192 | A-Kinase Anchoring Protein 4 (AKAP4) is an ERK1/2 substrate and a switch molecule between cAMP/PKA and PKC/ERK1/2 in human spermatozoa |
| Q77195545 | AP1 Proteins Mediate the cAMP Response of the Dopamine β-Hydroxylase Gene |
| Q34186921 | Abnormalities of cAMP signaling in affective disorders: implication for pathophysiology and treatment |
| Q52030670 | Activation and degradation of the transcription factor C/EBP during long-term facilitation in Aplysia |
| Q34577068 | Activation and function of the Rap1 GTPase in B lymphocytes |
| Q34677473 | Activation and targeting of mitogen-activated protein kinases by G-protein-coupled receptors. |
| Q38480691 | Activation of B-Raf and regulation of the mitogen-activated protein kinase pathway by the G(o) alpha chain |
| Q35117306 | Activation of B-Raf kinase requires phosphorylation of the conserved residues Thr598 and Ser601. |
| Q33861464 | Activation of C3G guanine nucleotide exchange factor for Rap1 by phosphorylation of tyrosine 504. |
| Q44497129 | Activation of ERK1/2 by platelet-activating factor receptor is independent of receptor internalisation and G-protein activation |
| Q28566717 | Activation of Gz attenuates Rap1-mediated differentiation of PC12 cells |
| Q42518440 | Activation of extracellular signal-regulated kinases 1 and 2 by depolarization stimulates tyrosine hydroxylase phosphorylation and dopamine synthesis in rat brain |
| Q40832428 | Activation of mitogen-activated protein kinases p42/44, p38, and stress-activated protein kinases in myelo-monocytic cells by Treponema lipoteichoic acid |
| Q43816439 | Activation of p59(Fyn) leads to melanocyte dedifferentiation by influencing MKP-1-regulated mitogen-activated protein kinase signaling. |
| Q46743337 | Activation of phospholipase D by 8-Br-cAMP occurs through novel pathway involving Src, Ras, and ERK in human endometrial stromal cells. |
| Q40676937 | Activation of protein kinase A induces neuronal differentiation of HiB5 hippocampal progenitor cells |
| Q38329782 | Activation of the Drosophila C3G leads to cell fate changes and overproliferation during development, mediated by the RAS-MAPK pathway and RAP1. |
| Q22010516 | Activation of the ERK/MAPK pathway by an isoform of rap1GAP associated with G alpha(i) |
| Q57372155 | Activation of the Rap GTPases in B Lymphocytes Modulates B Cell Antigen Receptor-induced Activation of Akt but Has No Effect on MAPK Activation |
| Q42830643 | Activation of the Rap1 guanine nucleotide exchange gene, CalDAG-GEF I, in BXH-2 murine myeloid leukemia |
| Q34378798 | Activation of the small GTPase Rap2B in agonist-stimulated human platelets |
| Q42461004 | Activity of Rap1 Is Regulated by Bombesin, Cell Adhesion, and Cell Density in NIH3T3 Fibroblasts |
| Q45050476 | Activity-dependent transcriptional activation and mRNA stabilization for cumulative expression of pituitary adenylate cyclase-activating polypeptide mRNA controlled by calcium and cAMP signals in neurons. |
| Q39148961 | Adenosine and adenosine receptors in the immunopathogenesis and treatment of cancer. |
| Q34487172 | Adenosine receptors: G protein-mediated signalling and the role of accessory proteins. |
| Q34010590 | Adenovirus-directed expression of Q227L-G alpha(s) inhibits growth of established tumors of later-stage human breast cancer cells in athymic mice |
| Q34109917 | Adenylyl cyclases types 1 and 8 promote pro-survival pathways after ethanol exposure in the neonatal brain |
| Q46843868 | Adrenergic receptor agonists prevent bile duct injury induced by adrenergic denervation by increased cAMP levels and activation of Akt. |
| Q62606472 | Altered Rap1 endogenous phosphorylation and levels in platelets from patients with bipolar disorder |
| Q35964699 | Amplification of CRKL induces transformation and epidermal growth factor receptor inhibitor resistance in human non-small cell lung cancers |
| Q30164083 | Amplification, up-regulation and over-expression of C3G (CRK SH3 domain-binding guanine nucleotide-releasing factor) in non-small cell lung cancers |
| Q78946402 | An extranuclear locus of cAMP-dependent protein kinase action is necessary and sufficient for promotion of spiral ganglion neuronal survival by cAMP |
| Q48034450 | Analysis of the Gs/Mitogen-activated Protein Kinase Pathway in Mutant S49 Cells |
| Q28571575 | Anaplastic lymphoma kinase activates the small GTPase Rap1 via the Rap1-specific GEF C3G in both neuroblastoma and PC12 cells |
| Q54541508 | Angiotensin-(1–7)-induced activation of ERK1/2 is cAMP/protein kinase A-dependent in glomerular mesangial cells |
| Q41654494 | Antagonism of Muscarinic Acetylcholine Receptors Alters Synaptic ERK Phosphorylation in the Rat Forebrain |
| Q48352760 | Arg3.1/Arc mRNA induction by Ca2+ and cAMP requires protein kinase A and mitogen-activated protein kinase/extracellular regulated kinase activation. |
| Q22008642 | Artemin, a novel member of the GDNF ligand family, supports peripheral and central neurons and signals through the GFRalpha3-RET receptor complex |
| Q80865450 | Artepillin C derived from propolis induces neurite outgrowth in PC12m3 cells via ERK and p38 MAPK pathways |
| Q40923762 | Astroglial differentiation of cortical precursor cells triggered by activation of the cAMP-dependent signaling pathway. |
| Q43931346 | Attenuation of protein kinase C and cAMP-dependent protein kinase signal transduction in the neurogranin knockout mouse. |
| Q40815599 | Autoregulation of cell-specific MAP kinase control of the tryptophan hydroxylase promoter. |
| Q35774155 | Axonal neuropathy-associated TRPV4 regulates neurotrophic factor-derived axonal growth. |
| Q40106302 | B- and C-RAF display essential differences in their binding to Ras: the isotype-specific N terminus of B-RAF facilitates Ras binding |
| Q33636207 | B-Raf and CRHR1 internalization mediate biphasic ERK1/2 activation by CRH in hippocampal HT22 Cells |
| Q28235023 | B-Raf and Raf-1 are regulated by distinct autoregulatory mechanisms |
| Q40520531 | B-Raf contributes to sustained extracellular signal-regulated kinase activation associated with interleukin-2 production stimulated through the T cell receptor. |
| Q28507477 | B-Raf-mediated signaling pathway regulates T cell development |
| Q28476616 | B-raf alternative splicing is dispensable for development but required for learning and memory associated with the hippocampus in the adult mouse |
| Q43559806 | Basic fibroblast growth factor-induced activation of novel CREB kinase during the differentiation of immortalized hippocampal cells |
| Q40885973 | Beta 3- and alpha1-adrenergic Erk1/2 activation is Src- but not Gi-mediated in Brown adipocytes |
| Q43821482 | Biolistic transfection and morphological analysis of cultured sympathetic neurons |
| Q77154628 | Biological activity of RE‐1 silencing transcription factor (REST) towards distinct transcriptional activators |
| Q36819052 | Biological characterization of Drosophila Rapgap1, a GTPase activating protein for Rap1 |
| Q39624770 | Bombyx Adipokinetic Hormone Receptor Activates Extracellular Signal-Regulated Kinase 1 and 2 via G Protein-Dependent PKA and PKC but β-Arrestin-Independent Pathways |
| Q33965534 | Both src-dependent and -independent mechanisms mediate phosphatidylinositol 3-kinase regulation of colony-stimulating factor 1-activated mitogen-activated protein kinases in myeloid progenitors |
| Q49084663 | Brain-derived neurotrophic factor causes cAMP response element-binding protein phosphorylation in absence of calcium increases in slices and cultured neurons from rat visual cortex. |
| Q44477195 | Brain-derived neurotrophic factor protection of cortical neurons from serum withdrawal-induced apoptosis is inhibited by cAMP. |
| Q39860663 | Breaking human cytomegalovirus major immediate-early gene silence by vasoactive intestinal peptide stimulation of the protein kinase A-CREB-TORC2 signaling cascade in human pluripotent embryonal NTera2 cells |
| Q30306708 | Brief treatments with forskolin enhance s-phase entry in balance epithelia from the ears of rats. |
| Q24561478 | Bromodomain protein Brd4 binds to GTPase-activating SPA-1, modulating its activity and subcellular localization |
| Q40680208 | CAMP-dependent protein kinase enhances CYP17 transcription via MKP-1 activation in H295R human adrenocortical cells |
| Q39540043 | CD28 and the tyrosine kinase lck stimulate mitogen-activated protein kinase activity in T cells via inhibition of the small G protein Rap1. |
| Q48543605 | CNS myelinogenesis in vitro: myelin basic protein deficient shiverer oligodendrocytes |
| Q42803832 | CUTL1 is phosphorylated by protein kinase A, modulating its effects on cell proliferation and motility |
| Q35765742 | Ca2+ -stimulated adenylyl cyclases regulate ERK-dependent activation of MSK1 during fear conditioning |
| Q36385160 | Ca2+ influx through L-type Ca2+ channels and Ca2+-induced Ca2+ release regulate cAMP accumulation and Epac1-dependent ERK 1/2 activation in INS-1 cells |
| Q30500617 | Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities. |
| Q40860240 | Calcium and cAMP signals differentially regulate cAMP-responsive element-binding protein function via a Rap1-extracellular signal-regulated kinase pathway |
| Q37893567 | Calcium signaling in cognition and aging-dependent cognitive decline |
| Q36757540 | Canadian Association of Neurosciences Review: the role of dopamine receptor function in neurodegenerative diseases. |
| Q39553440 | Cannabinoid CB1 receptors transactivate multiple receptor tyrosine kinases and regulate serine/threonine kinases to activate ERK in neuronal cells. |
| Q64111949 | Cascade Signals of Papaverine Inhibiting LPS-Induced Retinal Microglial Activation |
| Q42810032 | Cell condition-dependent regulation of ERK5 by cAMP. |
| Q41790957 | Cell contact-dependent functional selectivity of β2-adrenergic receptor ligands in stimulating cAMP accumulation and extracellular signal-regulated kinase phosphorylation |
| Q30692017 | Cell cycle-dependent subcellular localization of exchange factor directly activated by cAMP. |
| Q28142961 | Cell type-specific regulation of B-Raf kinase by cAMP and 14-3-3 proteins |
| Q33638611 | Cellular aspects of trophic actions in the nervous system. |
| Q34197634 | Central vagal afferent endings mediate reduction of food intake by melanocortin-3/4 receptor agonist |
| Q22010383 | Characterization of GFR, a novel guanine nucleotide exchange factor for Rap1 |
| Q33740213 | Characterization of the B-Raf interactome in mouse hippocampal neuronal cells |
| Q40268739 | Characterization of the GbpD-activated Rap1 pathway regulating adhesion and cell polarity in Dictyostelium discoideum |
| Q31029983 | Characterization of the Gene EPAC2: Structure, Chromosomal Localization, Tissue Expression, and Identification of the Liver-Specific Isoform |
| Q34310158 | Cholecystokinin gene transcription: promoter elements, transcription factors and signaling pathways |
| Q40893610 | Chronic fentanyl treatments induce the up-regulation of mu opioid receptor mRNA in rat pheochromocytoma cells |
| Q37154507 | Circadian regulation of cGMP-gated channels of vertebrate cone photoreceptors: role of cAMP and Ras. |
| Q41753643 | Coactivation of beta-adrenergic and cholinergic receptors enhances the induction of long-term potentiation and synergistically activates mitogen-activated protein kinase in the hippocampal CA1 region. |
| Q38342952 | Cocaine-induced intracellular signaling and gene expression are oppositely regulated by the dopamine D1 and D3 receptors. |
| Q39456844 | Combinatorial effect of T-cell receptor ligation and CD45 isoform expression on the signaling contribution of the small GTPases Ras and Rap1. |
| Q35194018 | Compartmentalization of protein kinase A signaling by the heterotrimeric G protein Go. |
| Q89838002 | Conformation-specific inhibitors of activated Ras GTPases reveal limited Ras dependency of patient-derived cancer organoids |
| Q40284486 | Constitutive ERK1/2 activation by a chimeric neurokinin 1 receptor-beta-arrestin1 fusion protein. Probing the composition and function of the G protein-coupled receptor "signalsome". |
| Q38469173 | Control of neurite outgrowth by RhoA inactivation |
| Q38289383 | Cooperation of protein kinase A and Ras/ERK signaling pathways is required for AP-1-mediated activation of fibroblast growth factor-inducible response element (FiRE). |
| Q39458220 | Coordinated regulation of Rap1 and thyroid differentiation by cyclic AMP and protein kinase A. |
| Q74230781 | Costimulation through CD28 Suppresses T Cell Receptor-dependent Activation of the Ras-like Small GTPase Rap1 in Human T Lymphocytes |
| Q44658014 | Coupling of neuronal 5‐HT7 receptors to activation of extracellular‐regulated kinase through a protein kinase A‐independent pathway that can utilize Epac |
| Q30167857 | Crk family adaptors-signalling complex formation and biological roles |
| Q30175335 | CrkL mediates Ras-dependent activation of the Raf/ERK pathway through the guanine nucleotide exchange factor C3G in hematopoietic cells stimulated with erythropoietin or interleukin-3. |
| Q34479232 | Cross talk between ERK and PKA is required for Ca2+ stimulation of CREB-dependent transcription and ERK nuclear translocation. |
| Q89604978 | Cross-Talk in Nucleotide Signaling in Glioma C6 Cells |
| Q42774583 | Crosstalk between G protein-coupled receptors (GPCRs) and tyrosine kinase receptor (TXR) in the heart after morphine withdrawal |
| Q28205761 | Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation |
| Q33687017 | Crosstalk between protein kinase A and growth factor receptor signaling pathways in arterial smooth muscle |
| Q97644151 | Cryptochrome 1 Alleviates the Antiproliferative Effect of Isoproterenol on Human Gastric Cancer Cells |
| Q42490416 | Culture-expanded human dermal stem cells exhibit donor to donor differences in cAMP generation. |
| Q41008887 | Cyclic AMP Elevation Is Sufficient to Promote the Survival of Spinal Motor NeuronsIn Vitro |
| Q32034757 | Cyclic AMP and mitogen-activated protein kinases are required for glutamate-dependent cyclic AMP response element binding protein and Elk-1 phosphorylation in the dorsal striatum in vivo |
| Q44247224 | Cyclic AMP induces activation of extracellular signal-regulated kinases in HL-60 cells: role in cAMP-induced differentiation |
| Q44129443 | Cyclic AMP induces transactivation of the receptors for epidermal growth factor and nerve growth factor, thereby modulating activation of MAP kinase, Akt, and neurite outgrowth in PC12 cells |
| Q40624986 | Cyclic AMP inhibits TGFβ1‐induced cell‐scattering and invasiveness in murine‐transformed keratinocytes |
| Q34162513 | Cyclic AMP-independent involvement of Rap1/B-Raf in the angiotensin II AT2 receptor signaling pathway in NG108-15 cells |
| Q34850793 | Cyclic AMP-mediated cyst expansion |
| Q39459257 | Cyclic AMP-mediated inhibition of cell growth requires the small G protein Rap1. |
| Q46630018 | Cyclic AMP-mediated regulation of transcription factor Lot1 expression in cerebellar granule cells |
| Q39576736 | Cyclic-GMP-dependent protein kinase inhibits the Ras/Mitogen-activated protein kinase pathway |
| Q40798208 | Cytokine-induced cell death in immortalized Schwann cells: roles of nitric oxide and cyclic AMP. |
| Q44067022 | D1 dopamine receptor regulation of microtubule-associated protein-2 phosphorylation in developing cerebral cortical neurons. |
| Q39402299 | DARPP-32 is required for MAPK/ERK signaling in thyroid cells |
| Q28182054 | DOCK4, a GTPase activator, is disrupted during tumorigenesis |
| Q28574593 | DYRK1A enhances the mitogen-activated protein kinase cascade in PC12 cells by forming a complex with Ras, B-Raf, and MEK1. |
| Q46607400 | Damage-induced activation of ERK1/2 in cochlear supporting cells is a hair cell death-promoting signal that depends on extracellular ATP and calcium. |
| Q40408138 | DeltaRaf-1:ER* bypasses the cyclic AMP block of extracellular signal-regulated kinase 1 and 2 activation but not CDK2 activation or cell cycle reentry |
| Q37218783 | Depolarization and cAMP elevation rapidly recruit TrkB to the plasma membrane of CNS neurons |
| Q28579147 | Depolarization-induced differentiation of PC12 cells is mediated by phospholipase D2 through the transcription factor CREB pathway |
| Q37180148 | Depression, social support, and beta-adrenergic transcription control in human ovarian cancer |
| Q28588899 | Diacylglycerol kinase iota regulates Ras guanyl-releasing protein 3 and inhibits Rap1 signaling |
| Q39924779 | Dietary polyphenols identified as intracellular protein kinase A inhibitors |
| Q34742655 | Differences in protein changes between stress‐induced premature senescence and replicative senescence states |
| Q42446574 | Different expression of adenylyl cyclase isoforms after retinoic acid induction of P19 teratocarcinoma cells. |
| Q39575058 | Differential Effects of Protein Kinase A on Ras Effector Pathways |
| Q40627291 | Differential Involvement of the Ras and Rap1 Small GTPases in Vasoactive Intestinal and Pituitary Adenylyl Cyclase Activating Polypeptides Control of the Prolactin Gene |
| Q39962632 | Differential cytotoxicity of novel somatostatin and dopamine chimeric compounds on bronchopulmonary and small intestinal neuroendocrine tumor cell lines |
| Q24674150 | Differential regulation of B-raf isoforms by phosphorylation and autoinhibitory mechanisms |
| Q40977058 | Differential regulation of MAP kinase activity by corticotropin-releasing hormone in normal and neoplastic corticotropes |
| Q31840769 | Differential regulation of mitogen-activated protein kinases ERK1/2 and ERK5 by neurotrophins, neuronal activity, and cAMP in neurons. |
| Q90084592 | Differentiation of Mesenchymal Stem Cells to Neuroglia: in the Context of Cell Signalling |
| Q24311922 | Direct binding of the beta1 adrenergic receptor to the cyclic AMP-dependent guanine nucleotide exchange factor CNrasGEF leads to Ras activation |
| Q77298424 | Discriminatory residues in Ras and Rap for guanine nucleotide exchange factor recognition |
| Q48406871 | Dissociation between genes activated in long-term potentiation and in spatial learning in the rat. |
| Q42797662 | Distinct roles of the adaptor protein Shc and focal adhesion kinase in integrin signaling to ERK. |
| Q73258738 | Distinct signaling pathways involved in multiple effects of basic fibroblast growth factor on cultured rat hippocampal neurons |
| Q34594482 | Diversity of G protein-coupled receptor signaling pathways to ERK/MAP kinase |
| Q35135602 | Does Rap1 deserve a bad Rap? |
| Q33876969 | Does ceramide play a role in neural cell apoptosis? |
| Q35721013 | Dopamine D1 receptors regulate protein synthesis-dependent long-term recognition memory via extracellular signal-regulated kinase 1/2 in the prefrontal cortex |
| Q28578325 | Dopamine promotes striatal neuronal apoptotic death via ERK signaling cascades |
| Q51851159 | Dorsomorphin stimulates neurite outgrowth in PC12 cells via activation of a protein kinase A-dependent MEK-ERK1/2 signaling pathway. |
| Q51084626 | Dose-dependent impairment of inhibitory avoidance retention in rats by immediate post-training infusion of a mitogen-activated protein kinase kinase inhibitor into cortical structures |
| Q34325514 | Drosophila PDZ-GEF, a guanine nucleotide exchange factor for Rap1 GTPase, reveals a novel upstream regulatory mechanism in the mitogen-activated protein kinase signaling pathway |
| Q42515402 | ERK Activation by G-protein-coupled Receptors in Mouse Brain Is Receptor Identity-specific |
| Q81236740 | ERK MAP kinase signaling in post-mortem brain of suicide subjects: differential regulation of upstream Raf kinases Raf-1 and B-Raf |
| Q39797974 | ERK activation and cell growth require CaM kinases in MCF-7 breast cancer cells |
| Q39749519 | ERK plays a regulatory role in induction of LTP by theta frequency stimulation and its modulation by beta-adrenergic receptors |
| Q37358152 | ERK5 activity is required for nerve growth factor-induced neurite outgrowth and stabilization of tyrosine hydroxylase in PC12 cells |
| Q40772038 | ERM Transactivation Is Up-regulated by the Repression of DNA Binding after the PKA Phosphorylation of a Consensus Site at the Edge of the ETS Domain |
| Q73653416 | Ectopic B-Raf expression enhances extracellular signal-regulated kinase (ERK) signaling in T cells and prevents antigen-presenting cell-induced anergy |
| Q28292424 | Effect of phosphorylation on activities of Rap1A to interact with Raf-1 and to suppress Ras-dependent Raf-1 activation |
| Q42369179 | Effects of acute cocaine on ERK and DARPP-32 phosphorylation pathways in the caudate-putamen of Fischer rats |
| Q42479762 | Effects of adrenomedullin on cultured rat cardiac myocytes and fibroblasts |
| Q38725492 | Effects of baicalin on alveolar fluid clearance and α-ENaC expression in rats with LPS-induced acute lung injury |
| Q39316324 | Effects of estradiol and progesterone on prolactin transcriptional activity in somatolactotrophic cells |
| Q24613576 | Effects of galanin on cocaine-mediated conditioned place preference and ERK signaling in mice |
| Q34520517 | Elucidating biological risk factors in suicide: Role of protein kinase A |
| Q43831376 | Endothelin downregulates the glutamate transporter GLAST in cAMP-differentiated astrocytes in vitro. |
| Q39879613 | Enhanced Rap1 activation and insulin secretagogue properties of an acetoxymethyl ester of an Epac-selective cyclic AMP analog in rat INS-1 cells: studies with 8-pCPT-2'-O-Me-cAMP-AM. |
| Q39847587 | Epac activation converts cAMP from a proliferative into a differentiation signal in PC12 cells |
| Q22008544 | Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP |
| Q40194706 | Epac- and Rap- independent ERK1/2 phosphorylation induced by Gs-coupled receptor stimulation in HEK293 cells |
| Q28582158 | Epac2 induces synapse remodeling and depression and its disease-associated forms alter spines |
| Q43859972 | Epac: a new cAMP target and new avenues in cAMP research |
| Q28566249 | Essential role of the redox-sensitive kinase p66shc in determining energetic and oxidative status and cell fate in neuronal preconditioning |
| Q34107645 | Estrogen Action Via the G Protein-Coupled Receptor, GPR30: Stimulation of Adenylyl Cyclase and cAMP-Mediated Attenuation of the Epidermal Growth Factor Receptor-to-MAPK Signaling Axis |
| Q44494851 | Evidence of increased dopamine receptor signaling in food-restricted rats |
| Q53656403 | Examining the mechanism of Erk nuclear translocation using green fluorescent protein |
| Q27863676 | Expression of cAMP-regulated guanine nucleotide exchange factors in pancreatic beta-cells |
| Q40859830 | Expression of cyclooxygenase 2 by prostaglandin E(2) in human endometrial adenocarcinoma cell line HEC-1B. |
| Q28578528 | Extracellular ATP stimulates an inhibitory pathway towards growth factor-induced cRaf-1 and MEKK activation in astrocyte cultures |
| Q39247983 | Extracellular Signal-Regulated Kinase in Nucleus Accumbens Mediates Propofol Self-Administration in Rats |
| Q42656809 | Extracellular signal-regulated activation of Rap1 fails to interfere in Ras effector signalling |
| Q53349753 | Extracellular signal-regulated kinase-dependent proliferation is mediated through the protein kinase A/B-Raf pathway in human uveal melanoma cells |
| Q33745304 | Extracellular-signal-regulated kinase signalling in neurons |
| Q74762771 | Fluid flow induces COX-2 expression in MC3T3-E1 osteoblasts via a PKA signaling pathway |
| Q35024993 | Follicle-stimulating hormone activates extracellular signal-regulated kinase but not extracellular signal-regulated kinase kinase through a 100-kDa phosphotyrosine phosphatase |
| Q48568000 | Functional components of fibroblast growth factor (FGF) signal transduction in pituitary cells. Identification of FGF response elements in the prolactin gene. |
| Q33883351 | Functional interaction between Galpha(z) and Rap1GAP suggests a novel form of cellular cross-talk |
| Q36150037 | Functional microarray analysis of differentially expressed genes in granulosa cells from women with polycystic ovary syndrome related to MAPK/ERK signaling |
| Q42836193 | Functional whole-genome analysis identifies Polo-like kinase 2 and poliovirus receptor as essential for neuronal differentiation upstream of the negative regulator alphaB-crystallin. |
| Q28142155 | Fyn and Lck tyrosine kinases regulate tyrosine phosphorylation of p105CasL, a member of the p130Cas docking protein family, in T-cell receptor-mediated signalling |
| Q36819372 | G protein regulation of MAPK networks |
| Q34502401 | G protein-coupled receptors: dominant players in cell-cell communication |
| Q34130876 | G-protein alpha(olf) subunit promotes cellular invasion, survival, and neuroendocrine differentiation in digestive and urogenital epithelial cells |
| Q28510679 | G-protein-coupled receptor-mediated activation of rap GTPases: characterization of a novel Galphai regulated pathway |
| Q40870320 | GTK, a Src-related tyrosine kinase, induces nerve growth factor-independent neurite outgrowth in PC12 cells through activation of the Rap1 pathway. Relationship to Shb tyrosine phosphorylation and elevated levels of focal adhesion kinase. |
| Q47933710 | GTPases in antigen receptor signalling |
| Q34148749 | Galpha and Gbeta gamma require distinct Src-dependent pathways to activate Rap1 and Ras. |
| Q40387355 | Glial cell line-derived neurotrophic factor-induced signaling in Schwann cells. |
| Q40584918 | Glucagon promotes cAMP-response element-binding protein phosphorylation via activation of ERK1/2 in MIN6 cell line and isolated islets of Langerhans |
| Q33942973 | Glucagon receptor activates extracellular signal-regulated protein kinase 1/2 via cAMP-dependent protein kinase |
| Q40715808 | Glucose-dependent insulinotropic polypeptide activates the Raf-Mek1/2-ERK1/2 module via a cyclic AMP/cAMP-dependent protein kinase/Rap1-mediated pathway. |
| Q37858400 | Glycosides, depression and suicidal behaviour: the role of glycoside-linked proteins. |
| Q41695587 | Growth Factors and Mitogen-Activated Protein Kinases |
| Q38702213 | Guanine nucleotide exchange factor Epac2-dependent activation of the GTP-binding protein Rap2A mediates cAMP-dependent growth arrest in neuroendocrine cells |
| Q28212652 | Guanine nucleotide exchange factors CalDAG-GEFI and CalDAG-GEFII are colocalized in striatal projection neurons |
| Q34452452 | Guanine-nucleotide exchange protein C3G activates JNK1 by a ras-independent mechanism. JNK1 activation inhibited by kinase negative forms of MLK3 and DLK mixed lineage kinases |
| Q36081548 | Heat‐labile enterotoxin‐induced activation of NF‐κB and MAPK pathways in intestinal epithelial cells impacts enterotoxigenicEscherichia coli(ETEC) adherence |
| Q37072161 | Hematopoietic protein tyrosine phosphatase mediates beta2-adrenergic receptor-induced regulation of p38 mitogen-activated protein kinase in B lymphocytes |
| Q28567778 | High glucose stimulates synthesis of fibronectin via a novel protein kinase C, Rap1b, and B-Raf signaling pathway |
| Q42181624 | High-level activation of cyclic AMP signaling attenuates bone morphogenetic protein 2-induced sympathoadrenal lineage development and promotes melanogenesis in neural crest cultures |
| Q46776155 | Hippocampal neurons express a calcineurin-activated adenylyl cyclase. |
| Q46944737 | Histamine protects against NMDA-induced necrosis in cultured cortical neurons through H receptor/cyclic AMP/protein kinase A and H receptor/GABA release pathways. |
| Q38320607 | Histone deacetylase inhibitor FK228 suppresses the Ras-MAP kinase signaling pathway by upregulating Rap1 and induces apoptosis in malignant melanoma |
| Q35630019 | Hormone-sensitive lipase--new roles for an old enzyme |
| Q33689727 | Human RAS superfamily proteins and related GTPases |
| Q38308048 | Human alpha (1,3)-fucosyltransferase IV (FUTIV) gene expression is regulated by elk-1 in the U937 cell line |
| Q33840139 | Human papillomavirus type 16 E6-induced degradation of E6TP1 correlates with its ability to immortalize human mammary epithelial cells |
| Q24291612 | Identification and characterization of RA-GEF-2, a Rap guanine nucleotide exchange factor that serves as a downstream target of M-Ras |
| Q28139186 | Identification and characterization of potential effector molecules of the Ras-related GTPase Rap2 |
| Q33887428 | Identification of a human brain-specific isoform of mammalian STE20-like kinase 3 that is regulated by cAMP-dependent protein kinase |
| Q38684499 | Identification of cCMP and cUMP Substrate Proteins and Cross Talk Between cNMPs |
| Q22254750 | Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interaction |
| Q35031425 | Identification of new X-chromosomal genes required for Drosophila oogenesis and novel roles for fs(1)Yb, brainiac and dunce |
| Q33940377 | Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells |
| Q40558805 | Impact of the mitogen-activated protein kinase pathway on parathyroid hormone-related protein actions in osteoblasts |
| Q35723724 | Impaired fertility and spermiogenetic disorders with loss of cell adhesion in male mice expressing an interfering Rap1 mutant |
| Q33702929 | In vivo imaging reveals PKA regulation of ERK activity during neutrophil recruitment to inflamed intestines |
| Q42435594 | Induction of S100B gene expression in long-term potentiation in the hippocampal CA1 field depends on activity of NMDA receptors. |
| Q77822199 | Induction of neurite extension and survival in pheochromocytoma cells by the Rit GTPase |
| Q39959950 | Inhibition of cyclooxygenase activity reduces rotavirus infection at a postbinding step |
| Q24295193 | Inhibition of neurite outgrowth by reduced level of NDRG4 protein in antisense transfected PC12 cells |
| Q77596575 | Innovative treatment programs against cancer. I. Ras oncoprotein as a molecular target |
| Q34436011 | Insights into the transcriptional regulation of steroidogenic enzymes and StAR |
| Q42446298 | Insulin and Epidermal Growth Factor Stimulate a Conformational Change in Rap1 and Dissociation of the CrkII-C3G Complex |
| Q42440687 | Insulin induces expression of adenosine kinase gene in rat lymphocytes by signaling through the mitogen-activated protein kinase pathway. |
| Q24533233 | Insulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes. |
| Q48021735 | Insulin signal transduction through protein kinase cascades |
| Q46384435 | Insulin-like growth factor 1 inhibits extracellular signal-regulated kinase to promote neuronal survival via the phosphatidylinositol 3-kinase/protein kinase A/c-Raf pathway. |
| Q38220165 | Interactions between Verticillium dahliae and its host: vegetative growth, pathogenicity, plant immunity |
| Q40659852 | Interactions of cyclic adenosine monophosphate, brain-derived neurotrophic factor, and glial cell line-derived neurotrophic factor treatment on the survival and growth of postnatal mesencephalic dopamine neurons in vitro |
| Q35061520 | Intercellular redistribution of cAMP underlies selective suppression of cancer cell growth by connexin26. |
| Q24746259 | Interleukin-6- and cyclic AMP-mediated signaling potentiates neuroendocrine differentiation of LNCaP prostate tumor cells. |
| Q52656382 | Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development. |
| Q48706436 | Intracellular events mediating insulin-like growth factor I-induced oligodendrocyte development: modulation by cyclic AMP. |
| Q28609098 | Intracellular signaling by the neural cell adhesion molecule |
| Q35024826 | Intracellular signals mediating the food intake-suppressive effects of hindbrain glucagon-like peptide-1 receptor activation |
| Q28645940 | Involvement of Elk-1 in L6E9 skeletal muscle differentiation |
| Q40992601 | Involvement of MAP kinase in the cyclic AMP induction of myelin basic protein gene expression |
| Q42519987 | Involvement of cAMP response element-binding protein in the regulation of cell proliferation and the prolactin promoter of lactotrophs in primary culture |
| Q37145561 | Involvement of protein kinase A in fibroblast growth factor-2-activated transcription |
| Q51423988 | Involvement of the extracellular signal-regulated kinase cascade for cocaine-rewarding properties. |
| Q33544248 | Is the Ras-MAPK signalling pathway necessary for long-term memory formation? |
| Q22007973 | JNKK1 organizes a MAP kinase module through specific and sequential interactions with upstream and downstream components mediated by its amino-terminal extension |
| Q73553336 | Learning-associated activation of nuclear MAPK, CREB and Elk-1, along with Fos production, in the rat hippocampus after a one-trial avoidance learning: abolition by NMDA receptor blockade |
| Q33819911 | Lessons from mouse models of thyroid cancer |
| Q42964565 | Loss of Prkar1a leads to Bcl-2 family protein induction and cachexia in mice. |
| Q95750940 | Low-density lipoprotein activates the small GTPases Rap1 and Ral in human platelets |
| Q22003726 | M-Ras/R-Ras3, a transforming ras protein regulated by Sos1, GRF1, and p120 Ras GTPase-activating protein, interacts with the putative Ras effector AF6 |
| Q33650641 | MAP kinase pathways |
| Q42440550 | MAP kinase translocates into the nucleus of the presynaptic cell and is required for long-term facilitation in Aplysia. |
| Q49201741 | MAPK and ERK polymorphisms are associated with PCOS risk in Chinese women |
| Q52031503 | MAPK and memory. |
| Q34039916 | MAPK signaling and the kidney |
| Q57818837 | MIF May Participate in Pathogenesis of Polycystic Ovary Syndrome in Rats through MAPK Signalling Pathway |
| Q33685175 | Making new connections: role of ERK/MAP kinase signaling in neuronal plasticity |
| Q58435171 | Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9 |
| Q24532168 | Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions |
| Q24545607 | Mechanism of the spatio-temporal regulation of Ras and Rap1. |
| Q34791143 | Mechanisms of smoking-related lung and pancreatic adenocarcinoma development |
| Q38124799 | Medicinal chemistry of fluorinated cyclic and acyclic nucleoside phosphonates. |
| Q24290802 | Membrane-associated guanylate kinase with inverted orientation (MAGI)-1/brain angiogenesis inhibitor 1-associated protein (BAP1) as a scaffolding molecule for Rap small G protein GDP/GTP exchange protein at tight junctions |
| Q46437133 | Metabotropic glutamate receptors and dopamine receptors cooperate to enhance extracellular signal-regulated kinase phosphorylation in striatal neurons. |
| Q64238135 | MicroRNA-23a-3p Inhibits Mucosal Melanoma Growth and Progression through Targeting Adenylate Cyclase 1 and Attenuating cAMP and MAPK Pathways |
| Q38794453 | Mitogen-activated protein kinase phosphatase-1: function and regulation in bone and related tissues |
| Q30303652 | Mitogen-activated protein kinases: specific messages from ubiquitous messengers |
| Q36491945 | Mitogenic and oncogenic properties of the small G protein Rap1b |
| Q48545452 | Modulation of PC12 Cell Viability by Forskolin-Induced Cyclic AMP Levels Through ERK and JNK Pathways: An Implication for L-DOPA-Induced Cytotoxicity in Nigrostriatal Dopamine Neurons |
| Q28611463 | Modulation of kinase activity and oncogenic properties by alternative splicing reveals a novel regulatory mechanism for B-Raf |
| Q36781068 | Modulation of neuronal excitability by serotonin-NMDA interactions in prefrontal cortex |
| Q30741758 | Modulation of rap activity by direct interaction of Galpha(o) with Rap1 GTPase-activating protein. |
| Q40659281 | Modulation of the N-type calcium channel gene expression by the alpha subunit of Go. |
| Q37671995 | Molecular Mechanism: ERK Signaling, Drug Addiction, and Behavioral Effects. |
| Q90319604 | Molecular Mechanisms of Early and Late LTP |
| Q34465498 | Molecular mechanisms for protein kinase A-mediated modulation of immune function |
| Q88227478 | Molecular mechanisms underlying striatal synaptic plasticity: relevance to chronic alcohol consumption and seeking |
| Q35073208 | Molecular profiles of mitogen activated protein kinase signaling pathways in orofacial development |
| Q28115996 | Multiple roles of Rap1 in hematopoietic cells: complementary versus antagonistic functions |
| Q46923162 | Multiple signaling pathways are involved in endothelin-1-induced brain endothelial cell migration |
| Q73738461 | Myeloproliferative stem cell disorders by deregulated Rap1 activation in SPA-1-deficient mice |
| Q49160543 | N-Methyl-D-aspartate receptors and p38 mitogen-activated protein kinase are required for cAMP-dependent cyclase response element binding protein and Elk-1 phosphorylation in the striatum |
| Q31523910 | N-methyl D-aspartate receptor-mediated bidirectional control of extracellular signal-regulated kinase activity in cortical neuronal cultures |
| Q54594146 | Na+/Ca2+ Exchanger Inhibitors Inhibit Neurite Outgrowth in PC12 Cells |
| Q34275278 | Nardosinone, the first enhancer of neurite outgrowth-promoting activity of staurosporine and dibutyryl cyclic AMP in PC12D cells |
| Q34221141 | Natriuretic peptide signalling: molecular and cellular pathways to growth regulation |
| Q28207982 | Nerve growth factor activates persistent Rap1 signaling in endosomes |
| Q50516943 | Nerve growth factor enhances the CRE-dependent transcriptional activity activated by nobiletin in PC12 cells. |
| Q43808672 | Nerve growth factor in combination with second messenger analogues causes neuronal differentiation of PC12 cells expressing a dominant inhibitory Ras protein without inducing activation of extracellular signal‐regulated kinases |
| Q54097897 | Nerve growth factor-stimulated B-Raf catalytic activity is refractory to inhibition by cAMP-dependent protein kinase |
| Q39688362 | Neurite outgrowth from PC12 cells by basic fibroblast growth factor (bFGF) is mediated by RhoA inactivation through p190RhoGAP and ARAP3. |
| Q28283027 | Neuroendocrine-like differentiation of non-small cell lung carcinoma cells: regulation by cAMP and the interaction of mac25/IGFBP-rP1 and 25.1 |
| Q36740342 | Neuronal polarity: from extracellular signals to intracellular mechanisms |
| Q33922344 | Neuroprotective effects of estrogens: potential mechanisms of action |
| Q39320874 | Neurotrophic Effect of Citrus Auraptene: Neuritogenic Activity in PC12 Cells |
| Q34091438 | Neurotrophic effect of citrus 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone: promotion of neurite outgrowth via cAMP/PKA/CREB pathway in PC12 cells |
| Q42454534 | Neurotrophins elevate cAMP to reach a threshold required to overcome inhibition by MAG through extracellular signal-regulated kinase-dependent inhibition of phosphodiesterase. |
| Q35149046 | New advances on prostate carcinogenesis and therapies: involvement of EGF-EGFR transduction system |
| Q36125100 | New insights into protease-activated receptor 4 signaling pathways in the pathogenesis of inflammation and neuropathic pain: a literature review |
| Q40737866 | New signaling pathway for parathyroid hormone and cyclic AMP action on extracellular-regulated kinase and cell proliferation in bone cells. Checkpoint of modulation by cyclic AMP. |
| Q38192030 | Newer targets for modulation of intraocular pressure: focus on adenosine receptor signaling pathways |
| Q38837269 | Nitric Oxide Synthase-2-Derived Nitric Oxide Drives Multiple Pathways of Breast Cancer Progression |
| Q43715971 | Nociceptor sensitization by extracellular signal-regulated kinases. |
| Q43772601 | Nonisotopic Methods for Detecting Activation of Small G Proteins |
| Q34414134 | Novel Rap1 dominant-negative mutants interfere selectively with C3G and Epac |
| Q36788564 | Novel aspects of G-protein-coupled receptor signalling--different ways to achieve specificity. |
| Q34024962 | On the mitogenic properties of Rap1b: cAMP-induced G(1)/S entry requires activated and phosphorylated Rap1b |
| Q37938862 | Opioid receptor trafficking and signaling: what happens after opioid receptor activation? |
| Q42504109 | Opposite regulation of cocaine-induced intracellular signaling and gene expression by dopamine D1 and D3 receptors |
| Q28574769 | Overexpression of nucleoside diphosphate kinases induces neurite outgrowth and their substitution to inactive forms leads to suppression of nerve growth factor- and dibutyryl cyclic AMP-induced effects in PC12D cells |
| Q28567610 | Overexpression of striatal enriched phosphatase (STEP) promotes the neurite outgrowth induced by a cAMP analogue in PC12 cells |
| Q35778142 | Oxidative neuronal injury. The dark side of ERK1/2. |
| Q40790669 | P21(Cip1) induced by Raf is associated with increased Cdk4 activity in hematopoietic cells. |
| Q37400030 | PACAP signaling to DREAM: a cAMP-dependent pathway that regulates cortical astrogliogenesis |
| Q48295228 | PACAP-38 protects cerebellar granule cells from apoptosis |
| Q22010969 | PDZ-GEF1, a guanine nucleotide exchange factor specific for Rap1 and Rap2 |
| Q42819518 | PKA phosphorylation of Src mediates cAMP's inhibition of cell growth via Rap1. |
| Q34453808 | PKA-dependent and PKA-independent pathways for cAMP-regulated exocytosis |
| Q24292179 | PLC-gamma1 enzyme activity is required for insulin-induced DNA synthesis |
| Q77752534 | Parallels between tuberous sclerosis complex and neurofibromatosis 1: common threads in the same tapestry |
| Q43754619 | Parathyroid hormone activation of map kinase in rat duodenal cells is mediated by 3',5'-cyclic AMP and Ca(2+). |
| Q41016395 | Parathyroid hormone responses of cyclic AMP-, serum- and phorbol ester-responsive reporter genes in osteoblast-like UMR-106 cells |
| Q73911632 | Pathways to transcription |
| Q48232747 | Patterned vision causes CRE-mediated gene expression in the visual cortex through PKA and ERK. |
| Q64927251 | Phosphorylation by PKA of a site unique to B-Raf kinase. |
| Q51243825 | Phosphorylation of Rap1 by cAMP-dependent Protein Kinase (PKA) Creates a Binding Site for KSR to Sustain ERK Activation by cAMP. |
| Q37117611 | Phosphorylation of Rap1GAP, a striatally enriched protein, by protein kinase A controls Rap1 activity and dendritic spine morphology |
| Q30500214 | Phosphorylation of STEF/Tiam2 by protein kinase A is critical for Rac1 activation and neurite outgrowth in dibutyryl cAMP-treated PC12D cells |
| Q33931187 | Phosphorylation of eukaryotic translation initiation factor 4E and eukaryotic translation initiation factor 4E-binding protein (4EBP) and their upstream signaling components undergo diurnal oscillation in the mouse hippocampus: implications for [...] |
| Q33860828 | Phosphorylation of the nuclear receptor SF-1 modulates cofactor recruitment: integration of hormone signaling in reproduction and stress |
| Q38294291 | Physical activity elicits sustained activation of the cyclic AMP response element-binding protein and mitogen-activated protein kinase in the rat hippocampus |
| Q37851164 | Physiopathology of somatolactotroph cells: from transduction mechanisms to cotargeting therapy. |
| Q33744662 | Pituitary adenylate cyclase-activating polypeptide (PACAP)/PAC1HOP1 receptor activation coordinates multiple neurotrophic signaling pathways: Akt activation through phosphatidylinositol 3-kinase gamma and vesicle endocytosis for neuronal survival |
| Q59812434 | Pleiotropic Effects of GLP-1 and Analogs on Cell Signaling, Metabolism, and Function |
| Q35564801 | Positional Control of Cell Fate Through Joint Integrin/Receptor Protein Kinase Signaling |
| Q34080535 | Positive and negative regulation of Raf kinase activity and function by phosphorylation |
| Q91801192 | Potential Benefits of Nobiletin, A Citrus Flavonoid, against Alzheimer's Disease and Parkinson's Disease |
| Q35381711 | Potentiation of carbachol-induced detrusor smooth muscle contractions by beta-adrenoceptor activation |
| Q81581176 | Prediction and validation of the distinct dynamics of transient and sustained ERK activation |
| Q37218819 | Prenatal ethanol exposure persistently impairs NMDA receptor-dependent activation of extracellular signal-regulated kinase in the mouse dentate gyrus |
| Q48161940 | Probing for drug-induced multiplex signal transduction pathways using high resolution two-dimensional gel electrophoresis: application to beta-adrenoceptor stimulation in the rat C6 glioma cell |
| Q28183254 | Profiling follicle stimulating hormone-induced gene expression changes in normal and malignant human ovarian surface epithelial cells |
| Q34982327 | Prostacyclin regulates bone growth via the Epac/Rap1 pathway |
| Q36602975 | Prostaglandin E2-increased thermosensitivity of anterior hypothalamic neurons is associated with depressed inhibition |
| Q42112951 | Protein Kinase A-independent Ras Protein Activation Cooperates with Rap1 Protein to Mediate Activation of the Extracellular Signal-regulated Kinases (ERK) by cAMP. |
| Q58307749 | Protein Kinase a functions as a negative regulator of c‐jun n‐terminal kinase but not of p38 mitogen‐activated protein Kinase in PC12 cells |
| Q40864427 | Protein kinase A activity is required for depolarization-induced proline-rich tyrosine kinase 2 and mitogen-activated protein kinase activation in PC12 cells |
| Q62606469 | Protein kinase A and Rap1 levels in platelets of untreated patients with major depression |
| Q44402859 | Protein kinase A and protein kinase C signaling pathway interaction in phenylethanolamine N‐methyltransferase gene regulation |
| Q42522435 | Protein kinase A balances the growth factor-induced Ras/ERK signaling |
| Q44317738 | Protein kinase A mediates cAMP-induced tyrosine phosphorylation of the epidermal growth factor receptor |
| Q37201168 | Protein kinase A-dependent phosphorylation of Rap1 regulates its membrane localization and cell migration |
| Q28582549 | Protein kinase A-independent activation of ERK and H,K-ATPase by cAMP in native kidney cells: role of Epac I |
| Q41812476 | Protein kinase a in cancer |
| Q77206434 | Protein kinase inhibitor H7 blocks the induction of immediate-early genes zif268 and c-fos by a mechanism unrelated to inhibition of protein kinase C but possibly related to inhibition of phosphorylation of RNA polymerase II |
| Q34602142 | Protein kinase signal transduction cascades in mammalian associative conditioning |
| Q23918164 | Protein phosphorylation cascades associated with methamphetamine-induced glial activation |
| Q42264400 | Proteolytic degradation of SCOP in the hippocampus contributes to activation of MAP kinase and memory |
| Q40858490 | Quantitative determination of Rap 1 activation in cyclic nucleotide-treated HL-60 leukemic cells: lack of Rap 1 activation in variant cells |
| Q51112497 | Quantitative mapping of microtubule-associated protein 2c (MAP2c) phosphorylation and regulatory protein 14-3-3ζ-binding sites reveals key differences between MAP2c and its homolog Tau. |
| Q24537710 | R-Ras3/M-Ras induces neuronal differentiation of PC12 cells through cell-type-specific activation of the mitogen-activated protein kinase cascade. |
| Q22010968 | RA-GEF, a novel Rap1A guanine nucleotide exchange factor containing a Ras/Rap1A-associating domain, is conserved between nematode and humans |
| Q24291243 | RA-GEF-1, a guanine nucleotide exchange factor for Rap1, is activated by translocation induced by association with Rap1*GTP and enhances Rap1-dependent B-Raf activation |
| Q92092913 | RAF dimers control vascular permeability and cytoskeletal rearrangements at endothelial cell-cell junctions |
| Q36106023 | RAP1-mediated MEK/ERK pathway defects in Kabuki syndrome |
| Q24532102 | RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao |
| Q24316181 | Raf family kinases: old dogs have learned new tricks |
| Q73477223 | Raf revealed in life-or-death decisions |
| Q28581195 | Raf-1 and B-Raf proteins have similar regional distributions but differential subcellular localization in adult rat brain |
| Q43867605 | Rap-specific GTPase activating protein follows an alternative mechanism |
| Q22010010 | Rap1 GTPase-activating protein SPA-1 negatively regulates cell adhesion |
| Q40835253 | Rap1 is activated by erythropoietin or interleukin-3 and is involved in regulation of beta1 integrin-mediated hematopoietic cell adhesion |
| Q42830846 | Rap1 mediates sustained MAP kinase activation induced by nerve growth factor |
| Q38335485 | Rap1 mutants with increased affinity for the guanine-nucleotide exchange factor C3G. |
| Q28591015 | Rap1 signaling prevents L-type calcium channel-dependent neurotransmitter release |
| Q34238051 | Rap1 signalling: adhering to new models |
| Q36322227 | Rap1 up-regulation and activation on plasma membrane regulates T cell adhesion. |
| Q28584307 | Rap1-mediated activation of extracellular signal-regulated kinases by cyclic AMP is dependent on the mode of Rap1 activation |
| Q53413567 | Rap1-suppressed tumorigenesis is concomitant with the interference in ras effector signaling. |
| Q35849580 | Rap1A Regulates Osteoblastic Differentiation via the ERK and p38 Mediated Signaling |
| Q54754056 | Rap1A and rap1B ras-family proteins are prominently expressed in the nucleus of squamous carcinomas: nuclear translocation of GTP-bound active form. |
| Q40833601 | Rap1A protein interferes with various MAP kinase activating pathways in skeletal myogenic cells |
| Q24646480 | Rap1a is a key regulator of fibroblast growth factor 2-induced angiogenesis and together with Rap1b controls human endothelial cell functions |
| Q33965081 | Rap2 as a slowly responding molecular switch in the Rap1 signaling cascade. |
| Q34282328 | RapGEF2 is essential for embryonic hematopoiesis but dispensable for adult hematopoiesis. |
| Q24296811 | Rapgef2 Connects GPCR-Mediated cAMP Signals to ERK Activation in Neuronal and Endocrine Cells |
| Q33634177 | Rare diseases. 1. Lymphangioleiomyomatosis: clinical features, management and basic mechanisms |
| Q39922812 | Ras mediates the cAMP-dependent activation of extracellular signal-regulated kinases (ERKs) in melanocytes |
| Q91783151 | Ras-Dependent Cell Fate Decisions Are Reinforced by the RAP-1 Small GTPase in Caenorhabditis elegans |
| Q34160428 | Ras-dependent ERK activation by the human G(s)-coupled serotonin receptors 5-HT4(b) and 5-HT7(a). |
| Q41659022 | Ras-like GTPases |
| Q37189612 | Ras-mutant cancer cells display B-Raf binding to Ras that activates extracellular signal-regulated kinase and is inhibited by protein kinase A phosphorylation |
| Q46384311 | Reactive oxygen species and protein kinases modulate the level of phospho-MEK-like proteins during human sperm capacitation |
| Q44615404 | Receptor protein tyrosine phosphatase alpha signaling is involved in androgen depletion-induced neuroendocrine differentiation of androgen-sensitive LNCaP human prostate cancer cells |
| Q24300047 | Regulation of Brain-Derived Neurotrophic Factor Exon IV Transcription through Calcium Responsive Elements in Cortical Neurons |
| Q35783154 | Regulation of ERK Kinase by MEK1 Kinase Inhibition in the Brain |
| Q38439535 | Regulation of RAF protein kinases in ERK signalling |
| Q24290369 | Regulation of a novel human phospholipase C, PLCepsilon, through membrane targeting by Ras |
| Q28565555 | Regulation of dendritic spine morphology by SPAR, a PSD-95-associated RapGAP |
| Q36769478 | Regulation of immune responses and hematopoiesis by the Rap1 signal |
| Q34467657 | Regulation of mitogen-activated protein kinase signaling networks by G protein-coupled receptors. |
| Q46078497 | Relaxin activates the MAP kinase pathway in human endometrial stromal cells |
| Q28343294 | Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis |
| Q43715902 | Requirement of Ras for the activation of mitogen-activated protein kinase by calcium influx, cAMP, and neurotrophin in hippocampal neurons. |
| Q40741931 | Requirement of the Caenorhabditis elegans RapGEF pxf-1 and rap-1 for epithelial integrity |
| Q33532779 | Retrotransposition and mutation events yield Rap1 GTPases with differential signalling capacity |
| Q44127157 | Rheb is in a high activation state and inhibits B-Raf kinase in mammalian cells |
| Q24557569 | Rit contributes to nerve growth factor-induced neuronal differentiation via activation of B-Raf-extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades |
| Q41745943 | Role of MAP kinase in neurons |
| Q43890935 | Role of cAMP, PKA and Rap1A in thyroid follicular cell survival |
| Q46945439 | Role of kinase suppressor of Ras-1 in neuronal survival signaling by extracellular signal-regulated kinase 1/2. |
| Q33966221 | Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1. |
| Q37708356 | Role of the glucagon-like-peptide-1 receptor in the control of energy balance |
| Q37720417 | Roles of Rap1 signaling in tumor cell migration and invasion |
| Q24299594 | SPAL, a Rap-specific GTPase activating protein, is present in the NMDA receptor-PSD-95 complex in the hippocampus |
| Q44660977 | SU1498, an inhibitor of vascular endothelial growth factor receptor 2, causes accumulation of phosphorylated ERK kinases and inhibits their activity in vivo and in vitro |
| Q33217392 | Selective activation of mitogen-activated protein (MAP) kinase kinase 3 and p38alpha MAP kinase is essential for cyclic AMP-dependent UCP1 expression in adipocytes |
| Q39949940 | Selective distribution of protein kinase A regulatory subunit RII{alpha} in rodent gliomas. |
| Q30472855 | Selective inhibition of prolactin gene transcription by the ETS-2 repressor factor |
| Q36209203 | Sensitivity of GBM cells to cAMP agonist-mediated apoptosis correlates with CD44 expression and agonist resistance with MAPK signaling. |
| Q46535519 | Serotonin 5-HT1A receptors regulate NMDA receptor channels through a microtubule-dependent mechanism. |
| Q39013628 | Serotonin induces the migration of PC12 cells via the serotonin receptor 6/cAMP/ERK pathway |
| Q44283536 | Serotonin persistently activates the extracellular signal-related kinase in sensory neurons of Aplysia independently of cAMP or protein kinase C. |
| Q34515800 | Serum- and glucocorticoid-inducible kinase SGK phosphorylates and negatively regulates B-Raf |
| Q41750250 | Signal Transduction through MAP Kinase Cascades |
| Q36682803 | Signal transduction mechanisms in memory disorders |
| Q35166852 | Signal transduction mediated by the Ras/Raf/MEK/ERK pathway from cytokine receptors to transcription factors: potential targeting for therapeutic intervention. |
| Q33899529 | Signaling from G protein-coupled receptors to ERK5/Big MAPK 1 involves Galpha q and Galpha 12/13 families of heterotrimeric G proteins. Evidence for the existence of a novel Ras AND Rho-independent pathway |
| Q35096131 | Signaling from cAMP/PKA to MAPK and synaptic plasticity |
| Q33923713 | Signaling networks: the origins of cellular multitasking |
| Q40889507 | Signaling through Ras is essential for ret oncogene-induced cell differentiation in PC12 cells. |
| Q35166514 | Signalling from adenosine receptors to mitogen-activated protein kinases |
| Q43279624 | Signalling pathways associated with 5-HT6 receptors: relevance for cognitive effects |
| Q60548369 | Small molecule inhibition of RAS/MAPK signaling ameliorates developmental pathologies of Kabuki Syndrome |
| Q28583173 | Soluble adenylyl cyclase mediates nerve growth factor-induced activation of Rap1 |
| Q34087763 | Somatostatin receptor 1 (SSTR1)-mediated inhibition of cell proliferation correlates with the activation of the MAP kinase cascade: role of the phosphotyrosine phosphatase SHP-2. |
| Q43768755 | Some forms of cAMP-mediated long-lasting potentiation are associated with release of BDNF and nuclear translocation of phospho-MAP kinase |
| Q46007957 | Spaced stimuli stabilize MAPK pathway activation and its effects on dendritic morphology. |
| Q41026756 | Sphingosine Kinase Mediates Cyclic AMP Suppression of Apoptosis in Rat Periosteal Cells |
| Q37614887 | Spinal muscular atrophy astrocytes exhibit abnormal calcium regulation and reduced growth factor production |
| Q54634464 | Stimulation of fibroblast proliferation by neokyotorphin requires Ca influx and activation of PKA, CaMK II and MAPK/ERK. |
| Q28769590 | Stimulation of gene induction and cell growth by the Ras effector Rlf |
| Q28189761 | Stimulation of lipolysis and hormone-sensitive lipase via the extracellular signal-regulated kinase pathway |
| Q40858441 | Stimulation of mitogen-activated protein kinase pathway in rat somatotrophs by growth hormone-releasing hormone |
| Q28513370 | Stimulation of the ERK pathway by GTP-loaded Rap1 requires the concomitant activation of Ras, protein kinase C, and protein kinase A in neuronal cells |
| Q73039142 | Stimulatory and inhibitory effects of adenosine A(2A) receptors on nerve growth factor-induced phosphorylation of extracellular regulated kinases 1/2 in PC12 cells |
| Q36076341 | Studies of the regulation and function of the Gs alpha gene Gnas using gene targeting technology |
| Q48441222 | Sustained activation of M-Ras induced by nerve growth factor is essential for neuronal differentiation of PC12 cells |
| Q33966465 | Sustained extracellular signal-regulated kinase 1/2 phosphorylation in neonate 6-hydroxydopamine-lesioned rats after repeated D1-dopamine receptor agonist administration: implications for NMDA receptor involvement |
| Q30310839 | Synergistic promotion of c-Src activation and cell migration by Cas and AND-34/BCAR3. |
| Q40264104 | TCR ligand avidity determines the mode of B-Raf/Raf-1/ERK activation leading to the activation of human CD4+ T cell clone. |
| Q92663940 | Targeting Aberrant RAS/RAF/MEK/ERK Signaling for Cancer Therapy |
| Q40602934 | Tauroursodeoxycholate inhibits human cholangiocarcinoma growth via Ca2+-, PKC-, and MAPK-dependent pathways |
| Q41045775 | The Cyclic Adenosine Monophosphate-dependent Protein Kinase (PKA) Is Required for the Sustained Activation of Mitogen-activated Kinases and Gene Expression by Nerve Growth Factor |
| Q24554547 | The E6 oncoproteins of high-risk papillomaviruses bind to a novel putative GAP protein, E6TP1, and target it for degradation |
| Q52131194 | The ERK-dependent signalling is stage-specifically modulated by FSH, during primary Sertoli cell maturation. |
| Q44600959 | The G(s)-coupled adenosine A(2B) receptor recruits divergent pathways to regulate ERK1/2 and p38. |
| Q28475701 | The Kunitz-like modulatory protein haemangin is vital for hard tick blood-feeding success |
| Q24679529 | The M-Ras-RA-GEF-2-Rap1 pathway mediates tumor necrosis factor-alpha dependent regulation of integrin activation in splenocytes |
| Q59138417 | The Many Faces of Rap1 GTPase |
| Q47823131 | The RAF family: an expanding network of post-translational controls and protein-protein interactions. |
| Q33890369 | The Rap1 GTPase functions as a regulator of morphogenesis in vivo |
| Q38321447 | The Ras mutant D119N is both dominant negative and activated |
| Q33792985 | The Ras-related protein, Rap1A, mediates thrombin-stimulated, integrin-dependent glioblastoma cell proliferation and tumor growth |
| Q35218537 | The Rho GTPase Rnd1 suppresses mammary tumorigenesis and EMT by restraining Ras-MAPK signalling. |
| Q50952310 | The VEGFR2 and PKA pathways converge at MEK/ERK1/2 to promote survival in serum deprived neuronal cells |
| Q73574737 | The activation of B-Raf and Raf-1 after electroconvulsive shock in the rat hippocampus |
| Q37151146 | The adiponectin receptors AdipoR1 and AdipoR2 activate ERK1/2 through a Src/Ras-dependent pathway and stimulate cell growth |
| Q34441228 | The alternative Epac/cAMP pathway and the MAPK pathway mediate hCG induction of leptin in placental cells |
| Q43090975 | The cAMP effector EPAC activates Elk1 transcription factor in prostate smooth muscle, and is a minor regulator of α1-adrenergic contraction |
| Q62606471 | The cAMP-dependent protein kinase substrate Rap1 in platelets from patients with obsessive compulsive disorder or schizophrenia |
| Q41022529 | The calcitonin receptor stimulates Shc tyrosine phosphorylation and Erk1/2 activation. Involvement of Gi, protein kinase C, and calcium. |
| Q34399191 | The central noradrenaline system and memory consolidation |
| Q44141102 | The endocannabinoid anandamide inhibits neuronal progenitor cell differentiation through attenuation of the Rap1/B-Raf/ERK pathway. |
| Q37098658 | The herpes simplex virus type 2 gene ICP10PK protects from apoptosis caused by nerve growth factor deprivation through inhibition of caspase-3 activation and XIAP up-regulation |
| Q46965251 | The hydrophobic amino acid cluster at the cytoplasmic end of transmembrane helix III modulates the coupling of the ß1-adrenergic receptor to Gs |
| Q40788732 | The inhibition of phosphatidylinositol-3-kinase induces neurite retraction and activates GSK3. |
| Q41895997 | The mitogen-activated protein (MAP) kinase cascade can either stimulate or inhibit DNA synthesis in primary cultures of rat hepatocytes depending upon whether its activation is acute/phasic or chronic. |
| Q48202783 | The mitogen-activated protein kinase cascade couples PKA and PKC to cAMP response element binding protein phosphorylation in area CA1 of hippocampus |
| Q36521972 | The neurotrophic effects of PACAP in PC12 cells: control by multiple transduction pathways. |
| Q24338247 | The novel cellular mechanism of human 5-HT6 receptor through an interaction with Fyn |
| Q34560197 | The other half of Hebb: K+ channels and the regulation of neuronal excitability in the hippocampus |
| Q73466742 | The p44/42 mitogen-activated protein kinase cascade is involved in the induction and maintenance of astrocyte stellation mediated by protein kinase C |
| Q48297819 | The requirement of Ras and Rap1 for the activation of ERKs by cAMP, PACAP, and KCl in cerebellar granule cells |
| Q44226145 | The requirement of specific membrane domains for Raf-1 phosphorylation and activation |
| Q44061979 | The role of cAMP-dependent signaling in receptor-recognized forms of alpha 2-macroglobulin-induced cellular proliferation |
| Q27028148 | The role of soluble adenylyl cyclase in neurite outgrowth |
| Q40977814 | The small G-proteins Rap 1 as potential targets of vasoactive intestinal peptide effects in the human clonic cancer cells HT29. |
| Q50335944 | The stability of the G protein-coupled receptor-beta-arrestin interaction determines the mechanism and functional consequence of ERK activation |
| Q42797563 | The stimulation of beta(3)-adrenoceptor causes phosphorylation of extracellular signal-regulated kinases 1 and 2 through a G(s)- but not G(i)-dependent pathway in 3T3-L1 adipocytes |
| Q24554448 | The strength of interaction at the Raf cysteine-rich domain is a critical determinant of response of Raf to Ras family small GTPases |
| Q43830029 | The transcription factors CREB and c‐Fos play key roles in NCAM‐mediated neuritogenesis in PC12‐E2 cells |
| Q36570909 | The β2-adrenoceptor activates a positive cAMP-calcium feedforward loop to drive breast cancer cell invasion. |
| Q33967880 | Thrombopoietin-mediated sustained activation of extracellular signal-regulated kinase in UT7-Mpl cells requires both Ras-Raf-1- and Rap1-B-Raf-dependent pathways |
| Q43771485 | Thyrotropin Activates Mitogen-Activated Protein Kinase Pathway in FRTL-5 by a cAMP-Dependent Protein Kinase A-Independent Mechanism |
| Q28583482 | Tissue inhibitor of metalloproteinase-2 promotes neuronal differentiation by acting as an anti-mitogenic signal |
| Q44306207 | Toosendanin induces outgrowth of neuronal processes and apoptosis in PC12 cells |
| Q33323383 | Topological analysis of MAPK cascade for kinetic ErbB signaling |
| Q40188594 | Transcriptional silencing of glucocorticoid-inducible phenylethanolamine N-methyltransferase expression by sequential signaling events |
| Q40885919 | Treatment of v-Ki-ras-transformed SVC1 cells with low retinoic acid induces malignancy reversion associated with ras p21 down-regulation |
| Q43739195 | Treprostinil inhibits the adhesion and differentiation of fibrocytes via the cyclic adenosine monophosphate-dependent and Ras-proximate protein-dependent inactivation of extracellular regulated kinase |
| Q28235129 | Trihydrophobin 1 is a new negative regulator of A-Raf kinase |
| Q28580161 | Tuberous sclerosis-2 tumor suppressor modulates ERK and B-Raf activity in transformed renal epithelial cells |
| Q45020492 | Tyrosine hydroxylase induction by basic fibroblast growth factor and cyclic AMP analogs in striatal neural stem cells: role of ERK1/ERK2 mitogen-activated protein kinase and protein kinase C. |
| Q54323671 | Underlying mechanisms of cAMP- and glucocorticoid-mediated inhibition of FasL expression in activation-induced cell death |
| Q44163241 | Up-regulation of the PACAP type-1 receptor (PAC1) promoter by neurotrophins in rat PC12 cells and mouse cerebellar granule cells via the Ras/mitogen-activated protein kinase cascade |
| Q28752600 | Upregulation and maintenance of gap junctional communication in lens cells |
| Q28572893 | Urocortin-Related Peptides Increase Interleukin-6 Output via Cyclic Adenosine 5′-Monophosphate-Dependent Pathways in A7r5 Aortic Smooth Muscle Cells |
| Q40812665 | VIP and peptides related to activity-dependent neurotrophic factor protect PC12 cells against oxidative stress |
| Q40507280 | Vasoactive intestinal peptide induces neuroendocrine differentiation in the LNCaP prostate cancer cell line through PKA, ERK, and PI3K. |
| Q44441659 | Vasoactive intestinal peptide stimulates proliferation in HT29 human colonic adenocarcinoma cells: concomitant activation of Ras/Rap1-B-Raf-ERK signalling pathway |
| Q38319884 | Vasoactive intestinal peptide upregulates MUC2 intestinal mucin via CREB/ATF1. |
| Q40518814 | Vasoactive intestinal peptide-induced neurite remodeling in human neuroblastoma SH-SY5Y cells implicates the Cdc42 GTPase and is independent of Ras-ERK pathway |
| Q26782585 | What links BRAF to the heart function? New insights from the cardiotoxicity of BRAF inhibitors in cancer treatment |
| Q33778269 | Zebrafish larvae lose vision at night. |
| Q46606774 | beta-Arrestin 2 expression determines the transcriptional response to lysophosphatidic acid stimulation in murine embryo fibroblasts. |
| Q24316949 | c-MYC activates protein kinase A (PKA) by direct transcriptional activation of the PKA catalytic subunit beta (PKA-Cbeta) gene |
| Q30168758 | c-Src signaling induced by the adapters Sin and Cas is mediated by Rap1 GTPase |
| Q43571780 | cAMP and calcium ionophore induce outgrowth of neuronal processes in PC12 mutant cells in which nerve growth factor-induced outgrowth of neuronal processes is impaired |
| Q60050562 | cAMP cascade leads to Ras activation in cortical neurons |
| Q55036224 | cAMP effects in neuroendocrine tumors: The role of Epac and PKA in cell proliferation and adhesion. |
| Q43701554 | cAMP potentiates H(2)O(2)-induced ERK1/2 phosphorylation without the requirement for MEK1/2 phosphorylation |
| Q35161430 | cAMP-dependent cytosolic mislocalization of p27(kip)-cyclin D1 during quinol-thioether-induced tuberous sclerosis renal cell carcinoma |
| Q49085695 | cAMP-dependent protein kinase induces cAMP-response element-binding protein phosphorylation via an intracellular calcium release/ERK-dependent pathway in striatal neurons |
| Q40527599 | cAMP-dependent protein kinase type I regulates ethanol-induced cAMP response element-mediated gene expression via activation of CREB-binding protein and inhibition of MAPK. |
| Q30475307 | cAMP-induced auditory supporting cell proliferation is mediated by ERK MAPK signaling pathway |
| Q36992955 | cAMP-mediated induction of cyclin E sensitizes growth-arrested adipose stem cells to DNA damage-induced apoptosis |
| Q35635556 | cAMP/PKA-mediated regulation of erythropoiesis |
| Q28728333 | miR-337-3p and Its Targets STAT3 and RAP1A Modulate Taxane Sensitivity in Non-Small Cell Lung Cancers |
| Q22010742 | nRap GEP: a novel neural GDP/GTP exchange protein for rap1 small G protein that interacts with synaptic scaffolding molecule (S-SCAM) |
| Q40775233 | p190RhoGAP and Rap-dependent RhoGAP (ARAP3) inactivate RhoA in response to nerve growth factor leading to neurite outgrowth from PC12 cells |
| Q53625386 | p73 cooperates with Ras in the activation of MAP kinase signaling cascade. |
| Q44524136 | sst2 Somatostatin receptor inhibits cell proliferation through Ras-, Rap1-, and B-Raf-dependent ERK2 activation |
| Q95834242 | β-Adrenergic receptor structure and function: molecular insights guiding the development of novel therapeutic strategies to treat malignancy |
| Q60530540 | β-Amyloid-induced calcium influx induces apoptosis in culture by oxidative stress rather than tau phosphorylation |
| Q41282699 | β-adrenergic signaling broadly contributes to LTP induction. |
| Q41005345 | β‐adrenergic and fibroblast growth factor receptors induce neuronal process outgrowth through different mechanisms |
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