Activation of Gz attenuates Rap1-mediated differentiation of PC12 cells

scientific journal article

Activation of Gz attenuates Rap1-mediated differentiation of PC12 cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M204074200
P698PubMed publication ID12198116

P2093author name stringPatrick J. Casey
Jingwei Meng
P2860cites workIdentification of a GTP-binding protein alpha subunit that lacks an apparent ADP-ribosylation site for pertussis toxinQ24296604
RGSZ1, a Gz-selective Regulator of G Protein Signaling Whose Action Is Sensitive to the Phosphorylation State of GzαQ24316172
Sequence analysis of cDNA and genomic DNA for a putative pertussis toxin-insensitive guanine nucleotide-binding regulatory protein alpha subunitQ24338196
A ras-related gene with transformation suppressor activityQ24338921
G-protein alpha-subunit expression, myristoylation, and membrane association in COS cellsQ24559862
Lipid modifications of G proteins: alpha subunits are palmitoylatedQ24563070
Localization of the rap1GAP catalytic domain and sites of phosphorylation by mutational analysisQ24601091
Coupling of the alpha 2-adrenergic receptor to the inhibitory G-protein Gi and adenylate cyclase in HT29 cellsQ27865304
Molecular cloning of a GTPase activating protein specific for the Krev-1 protein p21rap1Q28115929
RGS10 is a selective activator of G alpha i GTPase activityQ28287882
The GTPase superfamily: a conserved switch for diverse cell functionsQ28302983
cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathwayQ28611450
Gz-mediated hormonal inhibition of cyclic AMP accumulationQ28646144
G protein mechanisms: insights from structural analysisQ29618461
Modulation of rap activity by direct interaction of Galpha(o) with Rap1 GTPase-activating protein.Q30741758
Functional interaction between Galpha(z) and Rap1GAP suggests a novel form of cellular cross-talkQ33883351
Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cellsQ33940377
RGSZ1 and Ret RGS: Two of Several Splice Variants from the Gene RGS20Q34104275
Rap1 signalling: adhering to new modelsQ34238051
Heterotrimeric G proteins: organizers of transmembrane signalsQ34317073
Specific neural and adrenal medullary antigens detected by antisera to clonal PC12 pheochromocytoma cellsQ35061555
Plasma Membrane Localization of GαzRequires Two SignalsQ36847578
Loss of signaling through the G protein, Gz, results in abnormal platelet activation and altered responses to psychoactive drugsQ37393641
Mutation analysis of the Epac--Rap1 signaling pathway in cold thyroid follicular adenomasQ38300428
Coordinated regulation of Rap1 and thyroid differentiation by cyclic AMP and protein kinase A.Q39458220
Cyclic AMP-mediated inhibition of cell growth requires the small G protein Rap1.Q39459257
RGS proteins and signaling by heterotrimeric G proteinsQ41378270
Mammalian RGS Proteins: Barbarians at the GateQ41682826
Rapid Ca2+-mediated activation of Rap1 in human plateletsQ42072243
The regulator of G protein signaling RGS4 selectively enhances alpha 2A-adreoreceptor stimulation of the GTPase activity of Go1alpha and Gi2alphaQ42487898
Rap1 mediates sustained MAP kinase activation induced by nerve growth factorQ42830846
High-pressure NMR study of the complex of a GTPase Rap1A with its effector RalGDS. A conformational switch in RalGDS revealed from non-linear pressure shifts.Q43767639
Fatty acylation of alpha z. Effects of palmitoylation and myristoylation on alpha z signalingQ46429289
Developmental expression of messenger RNA levels of the α subunit of the GTP-binding protein, Gz, in the mouse nervous systemQ48443207
Hypertolerance to morphine in G(z alpha)-deficient miceQ73930235
P433issue45
P407language of work or nameEnglishQ1860
P304page(s)43417–43424
P577publication date2002-11-08
P1433published inJournal of Biological ChemistryQ867727
P1476titleActivation of Gz attenuates Rap1-mediated differentiation of PC12 cells
P478volume277

Reverse relations

cites work (P2860)
Q28577635A role for G(z) in pancreatic islet beta-cell biology
Q51736755C3G dynamically associates with nuclear speckles and regulates mRNA splicing
Q35791574Cortex Mori Radicis Extract induces neurite outgrowth in PC12 cells activating ERK signaling pathway via inhibiting Ca(2+) influx
Q36016914Deletion of GαZ Protein Protects against Diet-induced Glucose Intolerance via Expansion of β-Cell Mass
Q33219481Differentiation of neuroblastoma cell line N1E-115 involves several signaling cascades
Q35135602Does Rap1 deserve a bad Rap?
Q37358152ERK5 activity is required for nerve growth factor-induced neurite outgrowth and stabilization of tyrosine hydroxylase in PC12 cells
Q26771178Function and Regulation of Heterotrimeric G Proteins during Chemotaxis
Q36289101G proteins in development
Q37880248Group II activators of G-protein signalling and proteins containing a G-protein regulatory motif.
Q33895342Gαz regulates BDNF-induction of axon growth in cortical neurons
Q82606560Multiple Gi proteins participate in nerve growth factor-induced activation of c-Jun N-terminal kinases in PC12 cells
Q34581746Novel somatic mutations in heterotrimeric G proteins in melanoma
Q37117611Phosphorylation of Rap1GAP, a striatally enriched protein, by protein kinase A controls Rap1 activity and dendritic spine morphology
Q40626548Phosphorylation-regulated Inhibition of the Gz GTPase-activating Protein Activity of RGS Proteins by Synapsin I
Q36322227Rap1 up-regulation and activation on plasma membrane regulates T cell adhesion.
Q28579227Rap1GAP inhibits tumor growth in oropharyngeal squamous cell carcinoma
Q37292561Rap1a null mice have altered myeloid cell functions suggesting distinct roles for the closely related Rap1a and 1b proteins
Q34206255Regulating Rap small G-proteins in time and space
Q24810130The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits
Q40609778Thyroid-stimulating hormone/cAMP and glycogen synthase kinase 3beta elicit opposing effects on Rap1GAP stability

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