The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits

scientific article

The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.7150/IJBS.1.51
P3181OpenCitations bibliographic resource ID1393792
P932PMC publication ID1142213
P698PubMed publication ID15951850
P5875ResearchGate publication ID7790549

P2093author name stringDavid P Siderovski
Francis S Willard
P2860cites workBiological functions and signaling of a transmembrane semaphorin, CD100/Sema4D.Q35652966
A G protein γ subunit-like domain shared between RGS11 and other RGS proteins specifies binding to G β5 subunitsQ22004020
Activation of the ERK/MAPK pathway by an isoform of rap1GAP associated with G alpha(i)Q22010516
Direct interaction of insulin-like growth factor-1 receptor with leukemia-associated RhoGEFQ24291941
Pleckstrin's repeat performance: a novel domain in G-protein signaling?Q48062692
Site of the previous meiotic division defines cleavage orientation in the mouse embryo.Q48557769
Distinct roles for Galpha and Gbetagamma in regulating spindle position and orientation in Caenorhabditis elegans embryosQ48561935
Tubulin binds specifically to the signal-transducing proteins, Gs alpha and Gi alpha 1.Q49130483
Selective regulation of Gq signaling by G protein-coupled receptor kinase 2: direct interaction of kinase N terminus with activated galphaqQ50336801
Characterization of leukemia-associated Rho guanine nucleotide exchange factor (LARG) expression during murine developmentQ52099851
AGS3: a G-Protein regulator of addiction-associated behaviors.Q52285256
Exchange of guanine nucleotides between tubulin and GTP-binding proteins that regulate adenylate cyclase: cytoskeletal modification of neuronal signal transductionQ54381189
RGS Proteins Determine Signaling Specificity of Gq-coupled ReceptorsQ60687223
Effects of Mg2+ and the beta gamma-subunit complex on the interactions of guanine nucleotides with G proteinsQ70322245
The use of CLUSTAL W and CLUSTAL X for multiple sequence alignmentQ73147826
PAR proteins regulate microtubule dynamics at the cell cortex in C. elegansQ73341305
Specific regulation of RGS2 messenger RNA by angiotensin II in cultured vascular smooth muscle cellsQ73487478
The N-terminal domain of RGS4 confers receptor-selective inhibition of G protein signalingQ77696554
Activation of RGS9-1GTPase acceleration by its membrane anchor, R9APQ78863307
A specific domain of Gialpha required for the transactivation of Gialpha by tubulin is implicated in the organization of cellular microtubulesQ78969635
RGS-PX1, a GAP for Gα s and Sorting Nexin in Vesicular TraffickingQ24291954
Structural basis for the selective activation of Rho GTPases by Dbl exchange factorsQ24297202
Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressureQ24299443
Identification and cDNA cloning of a novel human mosaic protein, LGN, based on interaction with G alpha i2Q24308852
GAIP, a protein that specifically interacts with the trimeric G protein G alpha i3, is a member of a protein family with a highly conserved core domainQ24311329
GTPase Activating Specificity of RGS12 and Binding Specificity of an Alternatively Spliced PDZ (PSD-95/Dlg/ZO-1) DomainQ24311627
Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene familyQ24323018
Molecular cloning and expression analysis of rat Rgs12 and Rgs14Q24324476
RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphaoQ24532102
R9AP, a membrane anchor for the photoreceptor GTPase accelerating protein, RGS9-1Q24533588
The semaphorin receptor plexin-B1 signals through a direct interaction with the Rho-specific nucleotide exchange factor, LARGQ24535768
Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF.Q24541352
Structural basis of the Axin-adenomatous polyposis coli interactionQ24594194
Cloning and mitochondrial localization of full-length D-AKAP2, a protein kinase A anchoring proteinQ24632727
Gbeta5 prevents the RGS7-Galphao interaction through binding to a distinct Ggamma-like domain found in RGS7 and other RGS proteinsQ24644618
Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11Q24651075
Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunitsQ27638907
TreeView: an application to display phylogenetic trees on personal computersQ27861074
Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit).Q27931672
Physiological characterization of Saccharomyces cerevisiae mutants supersensitive to G1 arrest by a factor and alpha factor pheromonesQ27933957
G protein alpha subunits activate tubulin GTPase and modulate microtubule polymerization dynamicsQ28142878
Modulation of Wnt signaling by Axin and AxilQ28143294
GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteinsQ28145018
The tetratricopeptide repeat: a structural motif mediating protein-protein interactionsQ28145758
The DEP Domain Determines Subcellular Targeting of the GTPase Activating Protein RGS9In VivoQ28183847
Snapin interacts with the N-terminus of regulator of G protein signaling 7Q28186584
Interaction of plexin-B1 with PDZ domain-containing Rho guanine nucleotide exchange factorsQ28198392
RGS12 and RGS14 GoLoco motifs are G alpha(i) interaction sites with guanine nucleotide dissociation inhibitor ActivityQ28198711
Mammalian Ric-8A (synembryn) is a heterotrimeric Galpha protein guanine nucleotide exchange factorQ28201257
B plexins activate Rho through PDZ-RhoGEFQ28206278
Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphologyQ28215013
The GoLoco motif: heralding a new tango between G protein signaling and cell division.Q35679392
Microtubule dynamic instability and GTP hydrolysisQ35836945
The G betagamma dimer as a novel source of selectivity in G-protein signaling: GGL-ing at convention.Q35860357
Role of palmitoylation in RGS protein functionQ35864179
Purification and in vitro functional analysis of the Arabidopsis thaliana regulator of G-protein signaling-1.Q35864250
AtRGS1 function in Arabidopsis thalianaQ35864256
RGS4 and GAIP are GTPase-activating proteins for Gq alpha and block activation of phospholipase C beta by gamma-thio-GTP-Gq alphaQ35951781
A complex of LIN-5 and GPR proteins regulates G protein signaling and spindle function inC. elegansQ35965179
Dynamic instability of individual microtubules analyzed by video light microscopy: rate constants and transition frequenciesQ36219356
RGS proteins reconstitute the rapid gating kinetics of Gβγ-activated inwardly rectifying K+ channelsQ36587667
A genetic selection for Caenorhabditis elegans synaptic transmission mutantsQ37243638
Assays of complex formation between RGS protein G gamma subunit-like domains and G beta subunitsQ38293456
G protein binding and G protein activation by nucleotide transfer involve distinct domains on tubulin: regulation of signal transduction by cytoskeletal elementsQ38319329
RGS2 binds directly and selectively to the M1 muscarinic acetylcholine receptor third intracellular loop to modulate Gq/11alpha signalingQ38344549
Asymmetrically distributed C. elegans homologs of AGS3/PINS control spindle position in the early embryoQ38353471
Role of nucleotide hydrolysis in the dynamics of actin filaments and microtubulesQ38659370
Dynamic regulation of RGS2 suggests a novel mechanism in G-protein signaling and neuronal plasticityQ39116365
GoLoco motif peptides as probes of Galpha subunit specificity in coupling of G-protein-coupled receptors to ion channels.Q40475275
Receptor-dependent RhoA activation in G12/G13-deficient cells: genetic evidence for an involvement of Gq/G11.Q40644445
Isolation and genetic analysis of Saccharomyces cerevisiae mutants supersensitive to G1 arrest by a factor and alpha factor pheromonesQ40679118
Bazooka provides an apical cue for Inscuteable localization in Drosophila neuroblastsQ40913027
The Aspergillus FlbA RGS domain protein antagonizes G protein signaling to block proliferation and allow developmentQ41077395
Deletion analysis of the Drosophila Inscuteable protein reveals domains for cortical localization and asymmetric localizationQ41607089
Lifetime Regulation of G Protein–Effector Complex: Emerging Importance of RGS ProteinsQ41698565
Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif.Q41837636
Heterotrimeric G proteins regulate daughter cell size asymmetry in Drosophila neuroblast divisions.Q42442212
A functional analysis of inscuteable and its roles during Drosophila asymmetric cell divisionsQ42470914
Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts.Q42480871
A protein complex containing Inscuteable and the Galpha-binding protein Pins orients asymmetric cell divisions in DrosophilaQ42486222
Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous systemQ42511782
Role of inscuteable in orienting asymmetric cell divisions in DrosophilaQ42522271
Inhibition of GDP/GTP exchange on G alpha subunits by proteins containing G-protein regulatory motifsQ43585971
Asymmetric segregation of Numb in retinal development and the influence of the pigmented epithelium.Q43683717
Quench-Flow Kinetic Measurement of Individual Reactions of G-Protein-Catalyzed GTPase CycleQ43842091
Fluorescence approaches to study G protein mechanisms.Q43842092
Specific binding of RGS9-Gbeta 5L to protein anchor in photoreceptor membranes greatly enhances its catalytic activityQ43990174
A spatial focusing model for G protein signals. Regulator of G protein signaling (RGS) protien-mediated kinetic scaffolding.Q44226118
Established and emerging fluorescence-based assays for G-protein function: heterotrimeric G-protein alpha subunits and regulator of G-protein signaling (RGS) proteins.Q44455801
Influence of cytosolic AGS3 on receptor--G protein couplingQ44496720
Differential contribution of GTPase activation and effector antagonism to the inhibitory effect of RGS proteins on Gq-mediated signaling in vivo.Q44664100
AGS3 and signal integration by Galpha(s)- and Galpha(i)-coupled receptors: AGS3 blocks the sensitization of adenylyl cyclase following prolonged stimulation of a Galpha(i)-coupled receptor by influencing processing of Galpha(i).Q44730636
Two RGS proteins that inhibit Galpha(o) and Galpha(q) signaling in C. elegans neurons require a Gbeta(5)-like subunit for functionQ47068883
Rapsynoid/partner of inscuteable controls asymmetric division of larval neuroblasts in Drosophila.Q47072851
Receptor- and nucleotide exchange-independent mechanisms for promoting G protein subunit dissociation.Q47735328
Analysis of partner of inscuteable, a novel player of Drosophila asymmetric divisions, reveals two distinct steps in inscuteable apical localizationQ47881793
Diversity in protein recognition by PTB domainsQ33801830
Dissecting the role of molecular motors in the mitotic spindleQ33853402
The GoLoco motif: a Galphai/o binding motif and potential guanine-nucleotide exchange factorQ33872778
Functional interaction between Galpha(z) and Rap1GAP suggests a novel form of cellular cross-talkQ33883351
Regulation of T cell activation, anxiety, and male aggression by RGS2.Q33920958
The role of Rho in G protein-coupled receptor signal transductionQ33932175
Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells.Q33953572
How motor proteins influence microtubule polymerization dynamicsQ34084535
RGS14 is a bifunctional regulator of Gαi/o activity that exists in multiple populations in brainQ34104625
Molecular Cloning of Regulators of G-Protein Signaling Family Members and Characterization of Binding Specificity of RGS 12 PDZ DomainQ34107384
Regulators of G-protein signalling as new central nervous system drug targets.Q34139169
Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient miceQ34177503
Translation of polarity cues into asymmetric spindle positioning in Caenorhabditis elegans embryosQ34197454
Ggamma-like (GGL) domains: new frontiers in G-protein signaling and beta-propeller scaffolding.Q34237416
Leukemia-associated Rho guanine nucleotide exchange factor promotes G alpha q-coupled activation of RhoA.Q34280883
Asymmetric cell division during animal developmentQ34286348
RGS21 is a novel regulator of G protein signalling selectively expressed in subpopulations of taste bud cellsQ34311223
RGS17/RGSZ2, a novel regulator of Gi/o, Gz, and Gq signalingQ34314895
Return of the GDI: the GoLoco motif in cell division.Q34326049
GTPase activity of the stimulatory GTP-binding regulatory protein of adenylate cyclase, Gs. Accumulation and turnover of enzyme-nucleotide intermediatesQ34563861
A role for RIC-8 (Synembryn) and GOA-1 (G(o)alpha) in regulating a subset of centrosome movements during early embryogenesis in Caenorhabditis elegans.Q34611222
The G-protein beta-subunit GPB-2 in Caenorhabditis elegans regulates the G(o)alpha-G(q)alpha signaling network through interactions with the regulator of G-protein signaling proteins EGL-10 and EAT-16Q34612427
A Purkinje cell differentiation marker shows a partial DNA sequence homology to the cellular sis/PDGF2 geneQ35169107
G-proteins as transducers in transmembrane signallingQ35178804
Regulation of G protein-linked guanine nucleotide exchange factors for Rho, PDZ-RhoGEF, and LARG by tyrosine phosphorylation: evidence of a role for focal adhesion kinaseQ28215911
Plexin B regulates Rho through the guanine nucleotide exchange factors leukemia-associated Rho GEF (LARG) and PDZ-RhoGEFQ28218379
Defects in RGS9 or its anchor protein R9AP in patients with slow photoreceptor deactivationQ28236836
Thrombin and lysophosphatidic acid receptors utilize distinct rhoGEFs in prostate cancer cellsQ28261735
EGL-10 regulates G protein signaling in the C. elegans nervous system and shares a conserved domain with many mammalian proteinsQ28272431
p115 RhoGEF, a GTPase Activating Protein for Gα 12 and Gα 13Q28274717
Direct Stimulation of the Guanine Nucleotide Exchange Activity of p115 RhoGEF by Gα 13Q28274727
A new family of regulators of G-protein-coupled receptors?Q28282833
GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunitsQ28286818
RGS family members: GTPase-activating proteins for heterotrimeric G-protein alpha-subunitsQ28287870
RGS10 is a selective activator of G alpha i GTPase activityQ28287882
RIC-8 (Synembryn): a novel conserved protein that is required for G(q)alpha signaling in the C. elegans nervous systemQ28344728
RGS8 accelerates G-protein-mediated modulation of K+currentsQ28565332
Activation of Gz attenuates Rap1-mediated differentiation of PC12 cellsQ28566717
Receptor-independent activators of heterotrimeric G-protein signaling pathwaysQ28569590
Receptor-selective effects of endogenous RGS3 and RGS5 to regulate mitogen-activated protein kinase activation in rat vascular smooth muscle cellsQ28570437
Tyrosine-kinase-dependent recruitment of RGS12 to the N-type calcium channelQ28579470
Complexes of the G protein subunit gbeta 5 with the regulators of G protein signaling RGS7 and RGS9. Characterization in native tissues and in transfected cellsQ28583318
The Many Faces of G Protein SignalingQ28608944
The GTPase activating factor for transducin in rod photoreceptors is the complex between RGS9 and type 5 G protein beta subunitQ28609908
Selective regulation of Galpha(q/11) by an RGS domain in the G protein-coupled receptor kinase, GRK2Q28611497
The influence of bound GDP on the kinetics of guanine nucleotide binding to G proteinsQ28646193
G proteins: transducers of receptor-generated signalsQ29547519
Enhanced genome annotation using structural profiles in the program 3D-PSSMQ29547847
Recent improvements to the SMART domain-based sequence annotation resourceQ29614230
Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome IIIQ29618444
Parsing the polarity codeQ30312126
Modulation of rap activity by direct interaction of Galpha(o) with Rap1 GTPase-activating protein.Q30741758
Stabilization of the GDP-bound conformation of Gialpha by a peptide derived from the G-protein regulatory motif of AGS3.Q30915703
The distribution of active force generators controls mitotic spindle positionQ31150806
Tubulin stimulates adenylyl cyclase activity in C6 glioma cells by bypassing the beta-adrenergic receptor: a potential mechanism of G protein activationQ31807583
A seven-transmembrane RGS protein that modulates plant cell proliferation.Q33339236
Whither goest the RGS proteins?Q33750131
Divergence of RGS proteins: evidence for the existence of six mammalian RGS subfamiliesQ33763322
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectpeptideQ172847
membrane proteinQ423042
transport proteinQ2111029
signal transductionQ828130
guanine nucleotide exchange factorsQ901088
enzymeQ8047
P304page(s)51-66
P577publication date2005-04-01
P13046publication type of scholarly workreview articleQ7318358
P1433published inInternational Journal of Biological SciencesQ6051326
P1476titleThe GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits
P478volume1

Reverse relations

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Q37974268Probing heterotrimeric G protein activation: applications to biased ligands.
Q38851156Protein Regulation in Signal Transduction
Q34832675Protein kinase C-α signals P115RhoGEF phosphorylation and RhoA activation in TNF-α-induced mouse brain microvascular endothelial cell barrier dysfunction
Q34509373Purification of heterotrimeric G protein alpha subunits by GST-Ric-8 association: primary characterization of purified G alpha(olf).
Q36532717R4 regulators of G protein signaling (RGS) identify an ancient MHC-linked synteny group
Q30596824RGS expression in cancer: oncomining the cancer microarray data
Q30498047RGS/Gi2alpha interactions modulate platelet accumulation and thrombus formation at sites of vascular injury
Q58701013RGS10 shapes the hemostatic response to injury through its differential effects on intracellular signaling by platelet agonists
Q46160241RGS12 Is a Novel Tumor-Suppressor Gene in African American Prostate Cancer That Represses AKT and MNX1 Expression
Q38960056RGS2 suppresses breast cancer cell growth via a MCPIP1-dependent pathway.
Q35867186RGS4 overexpression in the rat dorsal striatum modulates mGluR5- and amphetamine-mediated behavior and signaling
Q48540394RGS4-dependent attenuation of M4 autoreceptor function in striatal cholinergic interneurons following dopamine depletion
Q47721650Rapid kinetic BRET measurements to monitor G protein activation by GPCR and non-GPCR proteins
Q37147806RasGAPs: a crucial regulator of extracellular stimuli for homeostasis of cellular functions.
Q46318346Recently duplicated plant heterotrimeric Gα proteins with subtle biochemical differences influence specific outcomes of signal-response coupling.
Q30010478Regulation of GPCR activity, trafficking and localization by GPCR-interacting proteins
Q38890948Regulation of RGS5 GAP activity by GPSM3.
Q36718369Regulation of neural progenitor cell state by ephrin-B
Q38706526Regulation of neurite morphogenesis by interaction between R7 regulator of G protein signaling complexes and G protein subunit Gα13.
Q36225760Regulation of the subcellular localization of the G-protein subunit regulator GPSM3 through direct association with 14-3-3 protein
Q26823214Regulator of G Protein Signaling 2: A Versatile Regulator of Vascular Function
Q64111802Regulator of G-Protein Signaling 16 Is a Negative Modulator of Platelet Function and Thrombosis
Q28576232Regulator of G-protein signaling 14 (RGS14) is a selective H-Ras effector
Q30425556Regulator of G-protein signaling 18 controls both platelet generation and function
Q37488182Regulator of G-protein signalling and GoLoco proteins suppress TRPC4 channel function via acting at Gαi/o
Q27346927Regulator of g protein signaling 3 modulates wnt5b calcium dynamics and somite patterning
Q37726354Regulators of G protein signaling proteins as central components of G protein-coupled receptor signaling complexes
Q37778514Regulators of G protein signaling proteins as targets for drug discovery.
Q27329917Resistance to inhibitors of cholinesterase (Ric)-8A and Gαi contribute to cytokinesis abscission by controlling vacuolar protein-sorting (Vps)34 activity
Q34133413Resistance to inhibitors of cholinesterase 8A catalyzes release of Galphai-GTP and nuclear mitotic apparatus protein (NuMA) from NuMA/LGN/Galphai-GDP complexes
Q28593620Retinal ON bipolar cells express a new PCP2 splice variant that accelerates the light response
Q35629671Rgs1 regulates multiple Galpha subunits in Magnaporthe pathogenesis, asexual growth and thigmotropism.
Q61443432RgsD negatively controls development, toxigenesis, stress response, and virulence in Aspergillus fumigatus
Q37860720Rho GTPases as regulators of morphological neuroplasticity
Q37408332Ric-8 proteins are molecular chaperones that direct nascent G protein α subunit membrane association
Q42068618Ric-8A, a Galpha protein guanine nucleotide exchange factor potentiates taste receptor signaling.
Q46777853Ric-8A, a guanine nucleotide exchange factor for heterotrimeric G proteins, is critical for cranial neural crest cell migration.
Q64684379Role of RGS12 in the differential regulation of kappa opioid receptor-dependent signaling and behavior
Q57210662Screen Targeting Lung and Prostate Cancer Oncogene Identifies Novel Inhibitors of RGS17 and Problematic Chemical Substructures
Q64986119Selective Role of RGS9-2 in Regulating Retrograde Synaptic Signaling of Indirect Pathway Medium Spiny Neurons in Dorsal Striatum.
Q24300711Selective role for RGS12 as a Ras/Raf/MEK scaffold in nerve growth factor-mediated differentiation
Q35159559Simvastatin enhances aquaporin-2 surface expression and urinary concentration in vasopressin-deficient Brattleboro rats through modulation of Rho GTPase
Q37272524Small molecule protein-protein interaction inhibitors as CNS therapeutic agents: current progress and future hurdles.
Q36709998Spindle regulation in neural precursors of flies and mammals
Q48100600Sporophyte Formation and Life Cycle Completion in Moss Requires Heterotrimeric G-Proteins
Q28291130Sticky signaling--adhesion class G protein-coupled receptors take the stage
Q92295748Structural basis for GPCR-independent activation of heterotrimeric Gi proteins
Q34504260Structural basis for activation of trimeric Gi proteins by multiple growth factor receptors via GIV/Girdin
Q64069267Structural design principles that underlie the multi-specific interactions of Gα with dissimilar partners
Q30482884Structural determinants underlying the temperature-sensitive nature of a Galpha mutant in asymmetric cell division of Caenorhabditis elegans
Q27650447Structural diversity in the RGS domain and its interaction with heterotrimeric G protein  -subunits
Q27662083Structure of Stenotrophomonas maltophilia FeoA complexed with zinc: a unique prokaryotic SH3-domain protein that possibly acts as a bacterial ferrous iron-transport activating factor
Q34395337Structure-Function Analysis of Rgs1 in Magnaporthe oryzae: Role of DEP Domains in Subcellular Targeting
Q36302314Suppression of the GTPase-activating protein RGS10 increases Rheb-GTP and mTOR signaling in ovarian cancer cells
Q35624796Systematic comparison of gene expression between murine memory and naive B cells demonstrates that memory B cells have unique signaling capabilities
Q35967378TNFAIP8: a new effector for Galpha(i) coupling to reduce cell death and induce cell transformation.
Q30671262Temporal phases of activity-dependent plasticity and memory are mediated by compartmentalized routing of MAPK signaling in aplysia sensory neurons
Q24316930The Apaf-1*procaspase-9 apoptosome complex functions as a proteolytic-based molecular timer
Q26824363The G protein α chaperone Ric-8 as a potential therapeutic target
Q39175928The GAPs, GEFs, GDIs and…now, GEMs: New kids on the heterotrimeric G protein signaling block
Q27334223The Late Endosomal HOPS Complex Anchors Active G-Protein Signaling Essential for Pathogenesis in Magnaporthe oryzae
Q37078065The RGS protein Crg2 regulates both pheromone and cAMP signalling in Cryptococcus neoformans
Q24673940The RGS protein inhibitor CCG-4986 is a covalent modifier of the RGS4 Galpha-interaction face
Q36373158The RGS proteins add to the diversity of soybean heterotrimeric G-protein signaling
Q37086123The Ras‐binding domain region of RGS14 regulates its functional interactions with heterotrimeric G proteins
Q39537696The Ric-8B gene is highly expressed in proliferating preosteoblastic cells and downregulated during osteoblast differentiation in a SWI/SNF- and C/EBPbeta-mediated manner
Q36113801The brain gene expression profile of dopamine D2/D3 receptors and associated signaling proteins following amphetamine self-administration
Q24605348The conserved L5 loop establishes the pre-powerstroke conformation of the Kinesin-5 motor, eg5
Q30397640The evolution of regulators of G protein signalling proteins as drug targets - 20 years in the making: IUPHAR Review 21.
Q37677301The evolution of the GPCR signaling system in eukaryotes: modularity, conservation, and the transition to metazoan multicellularity
Q37577613The glycerophosphoinositols: cellular metabolism and biological functions.
Q33731341The gut-brain axis: is intestinal inflammation a silent driver of Parkinson's disease pathogenesis?
Q33342276The plastid protein THYLAKOID FORMATION1 and the plasma membrane G-protein GPA1 interact in a novel sugar-signaling mechanism in Arabidopsis
Q50529933The role of PLDα1 in providing specificity to signal-response coupling by heterotrimeric G-protein components in Arabidopsis
Q38710732The untapped potential of tyrosine-based G protein signaling
Q35644644Therapeutic effects of cell-permeant peptides that activate G proteins downstream of growth factors.
Q34310119Thinking outside of the "RGS box": new approaches to therapeutic targeting of regulators of G protein signaling.
Q89964984Top Common Differentially Expressed Genes in the Epileptogenic Nucleus of Two Strains of Rodents Susceptible to Audiogenic Seizures: WAR and GASH/Sal
Q33642440Transcriptome analyses and differential gene expression in a non-model fish species with alternative mating tactics.
Q42183560Two chimeric regulators of G-protein signaling (RGS) proteins differentially modulate soybean heterotrimeric G-protein cycle
Q24606708Type 5 G Protein β Subunit (Gβ5) Controls the Interaction of Regulator of G Protein Signaling 9 (RGS9) with Membrane Anchors
Q49571780Tyrosine phosphorylation switching of a G protein substrate
Q90729270Unusually persistent Gαi-signaling of the neuropeptide Y2 receptor depletes cellular Gi/o pools and leads to a Gi-refractory state
Q39016566Xenopus as a model organism to study heterotrimeric G-protein pathway during collective cell migration of neural crest
Q47642691miR-1260b promotes cell migration and invasion of hepatocellular carcinoma by targeting the regulator of G-protein signaling 22.
Q44120774mrflbA, encoding a putative FlbA, is involved in aerial hyphal development and secondary metabolite production in Monascus ruber M-7
Q31148783p120RasGAP is a mediator of rho pathway activation and tumorigenicity in the DLD1 colorectal cancer cell line
Q42925736p63RhoGEF—a key mediator of angiotensin II-dependent signaling and processes in vascular smooth muscle cells
Q46932018xRic-8 is a GEF for Gsalpha and participates in maintaining meiotic arrest in Xenopus laevis oocytes
Q35621371β2-Adrenoceptor agonist-induced RGS2 expression is a genomic mechanism of bronchoprotection that is enhanced by glucocorticoids

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