| scholarly article | Q13442814 |
| P356 | DOI | 10.1172/JCI15598 |
| P8608 | Fatcat ID | release_bfjm2brik5at3n6au5zwochdjm |
| P932 | PMC publication ID | 151918 |
| P698 | PubMed publication ID | 12588882 |
| P50 | author | Josef Penninger | Q1674391 |
| P2093 | author name string | Robert P Mecham | |
| Xiaoguang Sun | |||
| Russell H Knutsen | |||
| J Michael Wyss | |||
| Anthony J Muslin | |||
| Kendall J Blumer | |||
| Kevin M Kaltenbronn | |||
| Ning Peng | |||
| Thomas H Steinberg | |||
| Antonio Oliveira-dos-Santos | |||
| Scott P Heximer | |||
| Man-Hee Rhee | |||
| P2860 | cites work | RGS2/G0S8 is a selective inhibitor of Gqα function | Q24648296 |
| GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins | Q28145018 | ||
| Characterization of a novel mammalian RGS protein that binds to Galpha proteins and inhibits pheromone signaling in yeast | Q28306561 | ||
| Disruption of the dopamine D3 receptor gene produces renin-dependent hypertension | Q28511119 | ||
| G protein selectivity is a determinant of RGS2 function. | Q30323308 | ||
| RGS2 regulates signal transduction in olfactory neurons by attenuating activation of adenylyl cyclase III. | Q32102010 | ||
| Molecular mechanisms of human hypertension | Q32138445 | ||
| Gene targeting approaches to analyzing hypertension. | Q33686736 | ||
| RGS4 causes increased mortality and reduced cardiac hypertrophy in response to pressure overload | Q33857945 | ||
| Regulation of T cell activation, anxiety, and male aggression by RGS2. | Q33920958 | ||
| Genetic polymorphisms in the renin-angiotensin system: relevance for susceptibility to cardiovascular disease | Q34116575 | ||
| Differential expression of a basic helix-loop-helix phosphoprotein gene, G0S8, in acute leukemia and localization to human chromosome 1q31. | Q34302798 | ||
| Vascular remodeling in hypertension: roles of apoptosis, inflammation, and fibrosis | Q34376476 | ||
| Genetic control of blood pressure and the angiotensinogen locus | Q34498129 | ||
| Systemic hypertension induced by hepatic overexpression of human preproendothelin-1 in rats | Q37361568 | ||
| Dynamic regulation of RGS2 suggests a novel mechanism in G-protein signaling and neuronal plasticity | Q39116365 | ||
| Angiotensin II type 2 receptor overexpression activates the vascular kinin system and causes vasodilation | Q40851849 | ||
| Changes in the balance of phosphoinositide 3-kinase/protein kinase B (Akt) and the mitogen-activated protein kinases (ERK/p38MAPK) determine a phenotype of visceral and vascular smooth muscle cells | Q40953884 | ||
| Models of experimental hypertension in mice. | Q41253768 | ||
| How receptors talk to trimeric G proteins | Q41382832 | ||
| Slowed recovery of rod photoresponse in mice lacking the GTPase accelerating protein RGS9-1. | Q41719683 | ||
| Pharmacological properties of endothelins and big endothelins in ketamine/xylazine or urethane anesthetized rats. | Q42513740 | ||
| A novel effect of angiotensin on renal sympathetic nerve activity in mice. | Q43591400 | ||
| Association study of the 5-HT(2A) receptor gene polymorphism, T102C and essential hypertension | Q43621837 | ||
| Vascular-targeted overexpression of G protein-coupled receptor kinase-2 in transgenic mice attenuates beta-adrenergic receptor signaling and increases resting blood pressure | Q43922014 | ||
| Renin-angiotensin system genetic polymorphisms and cerebral white matter lesions in essential hypertension | Q48667673 | ||
| Role of AT(1) receptors and autonomic nervous system in mediating acute pressor responses to ANG II in anesthetized mice | Q51432835 | ||
| Vasopressin and angiotensin II in blood pressure control during isoflurane anesthesia in rats | Q51440457 | ||
| Heterozygous knock-Out of ET(B) receptors induces BQ-123-sensitive hypertension in the mouse | Q52171865 | ||
| beta2-adrenergic receptor polymorphisms at amino acid 16 differentially influence agonist-stimulated blood pressure and peripheral blood flow in normal individuals | Q52919503 | ||
| Beta(2)-adrenoceptor polymorphism determines vascular reactivity in humans | Q54036891 | ||
| Angiotensin II Stimulates Synthesis of Endothelial Nitric Oxide Synthase | Q54148281 | ||
| Role of the postsynaptic α2-adrenergic receptor subtypes in catecholamine-induced vasoconstriction | Q62090248 | ||
| Multilocus linkage of familial hyperkalaemia and hypertension, pseudohypoaldosteronism type II, to chromosomes 1q31-42 and 17p11-q21 | Q64050276 | ||
| Contribution of the sympathetic nervous system to hypertensive response to insulin excess in spontaneously hypertensive rats | Q71630180 | ||
| Angiotensin II activates endothelial constitutive nitric oxide synthase via AT1 receptors | Q71726329 | ||
| Specific regulation of RGS2 messenger RNA by angiotensin II in cultured vascular smooth muscle cells | Q73487478 | ||
| Positional genomic analysis identifies the beta(2)-adrenergic receptor gene as a susceptibility locus for human hypertension | Q73929740 | ||
| Regulatory effects of phospholamban on cardiac function in intact mice | Q74065725 | ||
| Angiotensin II stimulates the production of NO and peroxynitrite in endothelial cells | Q74153456 | ||
| Polymorphism in the beta(1)-adrenergic receptor gene and hypertension | Q74180003 | ||
| Extracellular ATP: a growth factor for vascular smooth muscle cells | Q74571996 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | hypertension | Q95566669 |
| P304 | page(s) | 445-452 | |
| P577 | publication date | 2003-02-01 | |
| P1433 | published in | Journal of Clinical Investigation | Q3186904 |
| P1476 | title | Hypertension and prolonged vasoconstrictor signaling in RGS2-deficient mice. | |
| P478 | volume | 111 |
| Q57298374 | A bronchoprotective role for in a murine model of lipopolysaccharide-induced airways inflammation |
| Q30427451 | AT1A angiotensin receptors in the renal proximal tubule regulate blood pressure |
| Q37776088 | Adrenergic Signaling Polymorphisms and Their Impact on Cardiovascular Disease |
| Q42734311 | Adrenergic response to maximum exercise of trained road cyclists. |
| Q39764882 | Analysis of RGS2 expression and prognostic significance in stage II and III colorectal cancer |
| Q42545079 | And the winner is ... RGS4! |
| Q38373127 | Angiotensin II and Cardiovascular-Renal Remodelling in Hypertension: Insights from a Human Model Opposite to Hypertension |
| Q35459372 | Anthrax Lethal Toxin-Induced Gene Expression Changes in Mouse Lung |
| Q37289767 | Antioxidant functions for the hemoglobin β93 cysteine residue in erythrocytes and in the vascular compartment in vivo |
| Q46214466 | Are RGS2 gene polymorphisms associated with high blood pressure in an ethnicity- and gender-specific manner? |
| Q44036246 | Association of genetic variations of regulator of G-protein signaling 2 with hypertension in the general Xinjiang Kazakh population |
| Q40289564 | Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodin |
| Q36174768 | Cardiotonic steroids stabilize regulator of G protein signaling 2 protein levels |
| Q27004543 | Cholinergic activity as a new target in diseases of the heart |
| Q37919731 | Control of Striatal Signaling by G Protein Regulators |
| Q36566328 | Control of mammalian G protein signaling by N-terminal acetylation and the N-end rule pathway |
| Q44628998 | Counter-regulation by atorvastatin of gene modulations induced by L-NAME hypertension is associated with vascular protection |
| Q28236836 | Defects in RGS9 or its anchor protein R9AP in patients with slow photoreceptor deactivation |
| Q24654920 | Deregulation of RGS2 in cardiovascular diseases |
| Q44504377 | Dexamethasone induction of hypertension and diabetes is PPAR-alpha dependent in LDL receptor-null mice |
| Q36852562 | Digoxin-Mediated Upregulation of RGS2 Protein Protects against Cardiac Injury. |
| Q34903113 | Does airway smooth muscle express an inflammatory phenotype in asthma? |
| Q98237765 | Dynamic control of tumor vasculature improves antitumor responses in a regional model of melanoma |
| Q50920264 | Effects of peroxisome proliferator-activated receptor-β activation in endothelin-dependent hypertension |
| Q52576782 | Endogenous RGS proteins modulate SA and AV nodal functions in isolated heart: implications for sick sinus syndrome and AV block |
| Q52591870 | Establishing a Split Luciferase Assay for Proteinkinase G (PKG) Interaction Studies |
| Q30176404 | FBXO44-Mediated Degradation of RGS2 Protein Uniquely Depends on a Cullin 4B/DDB1 Complex. |
| Q39679879 | Functional interaction of regulator of G protein signaling-2 with melanin-concentrating hormone receptor 1. |
| Q37627848 | Functional role, mechanisms of regulation, and therapeutic potential of regulator of G protein signaling 2 in the heart |
| Q42522589 | G12-G13-LARG-mediated signaling in vascular smooth muscle is required for salt-induced hypertension |
| Q37171659 | GNAI2 and regulators of G protein signaling as a potential Noonan syndrome mechanism |
| Q57178844 | Genetic Analysis of Rare Human Variants of Regulators of G Protein Signaling Proteins and Their Role in Human Physiology and Disease |
| Q37953793 | Genetic contributions to behavioural diversity at the gene-environment interface |
| Q50989320 | Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mice. |
| Q35884704 | Genetic variations related to hypertension: a review. |
| Q36722035 | Genetics of arterial hypertension and hypotension |
| Q36174271 | Group VIA phospholipase A2 (iPLA2beta) participates in angiotensin II-induced transcriptional up-regulation of regulator of g-protein signaling-2 in vascular smooth muscle cells |
| Q36838219 | Hypertension in mice with transgenic activation of the brain renin-angiotensin system is vasopressin dependent |
| Q28744247 | Identification of Genes and Networks Driving Cardiovascular and Metabolic Phenotypes in a Mouse F2 Intercross |
| Q28577952 | Identification of a cAMP-response element in the regulator of G-protein signaling-2 (RGS2) promoter as a key cis-regulatory element for RGS2 transcriptional regulation by angiotensin II in cultured vascular smooth muscles |
| Q37726386 | Identification of ligands targeting RGS proteins high-throughput screening and therapeutic potential |
| Q35217677 | Identification of protein kinase C activation as a novel mechanism for RGS2 protein upregulation through phenotypic screening of natural product extracts. |
| Q42873285 | Impact of RGS2 deficiency on the therapeutic effect of telmisartan in angiotensin II-induced aortic aneurysm |
| Q53808003 | Impaired response of regulator of Gαq signaling-2 mRNA to angiotensin II and hypertensive renal injury in Dahl salt-sensitive rats |
| Q44922297 | Inhibition of Galphaq-dependent PLC-beta1 activity by PKG and PKA is mediated by phosphorylation of RGS4 and GRK2. |
| Q37880333 | Intracellular regulation of heterotrimeric G-protein signaling modulates vascular smooth muscle cell contraction |
| Q35842514 | Is RGS-2 a new drug development target in cardiovascular disease? |
| Q38371546 | Knowledge-Based Compact Disease Models: A Rapid Path from High-Throughput Data to Understanding Causative Mechanisms for a Complex Disease |
| Q35033039 | Knowledge-based compact disease models identify new molecular players contributing to early-stage Alzheimer's disease |
| Q45934385 | LPS differentially affects vasoconstrictor responses: a potential role for RGS16? |
| Q90308874 | Mechanistic role of the CREB-regulated transcription coactivator 1 in cardiac hypertrophy |
| Q38793780 | Molecular genetics of essential hypertension |
| Q35838104 | Molecular mechanism of macrophage activation by red ginseng acidic polysaccharide from Korean red ginseng |
| Q41816625 | NO-dependent blood pressure regulation in RGS2-deficient mice |
| Q34023105 | Non-dipping and arterial hypertension depend on clinical factors rather than on genetic variability of ACE and RGS2 genes in patients with type 1 diabetes |
| Q34044364 | Novel insights into the mechanisms mediating the local antihypertrophic effects of cardiac atrial natriuretic peptide: role of cGMP-dependent protein kinase and RGS2. |
| Q45385913 | Origin‐specific epigenetic program correlates with vascular bed‐specific differences inRgs5expression |
| Q30425676 | PDGF-dependent regulation of regulator of G protein signaling-5 expression and vascular smooth muscle cell functionality |
| Q85908095 | Perturbation of chemical coupling by an endothelial Cx40 mutant attenuates endothelium-dependent vasodilation by KCa channels and elevates blood pressure in mice |
| Q38022144 | Pharmacogenomic approaches to study the effects of antihypertensive drugs |
| Q38919056 | Physiological functions and clinical implications of the N-end rule pathway |
| Q43093663 | Platelet Gs hypofunction and abnormal morphology resulting from a heterozygous RGS2 mutation. |
| Q46612234 | Potent inhibition of angiotensin AT1 receptor signaling by RGS8: importance of the C-terminal third exon part of its RGS domain |
| Q34218218 | Promoter Polymorphism of RGS2 Gene Is Associated with Change of Blood Pressure in Subjects with Antihypertensive Treatment: The Azelnidipine and Temocapril in Hypertensive Patients with Type 2 Diabetes Study |
| Q36255835 | Protective Roles for RGS2 in a Mouse Model of House Dust Mite-Induced Airway Inflammation. |
| Q47703780 | Proteolytic degradation of regulator of G protein signaling 2 facilitates temporal regulation of Gq/11 signaling and vascular contraction |
| Q36301542 | R4 RGS proteins: regulation of G-protein signaling and beyond |
| Q38644453 | R4 Regulator of G Protein Signaling (RGS) Proteins in Inflammation and Immunity |
| Q41875965 | RGS Proteins in Heart: Brakes on the Vagus. |
| Q35864233 | RGS-insensitive G-protein mutations to study the role of endogenous RGS proteins |
| Q37153202 | RGS2 and generalized anxiety disorder in an epidemiologic sample of hurricane-exposed adults |
| Q85231387 | RGS2 determines the preventive effects of ARBs against vascular remodeling: toward personalized medicine of anti-hypertensive therapy with ARBs |
| Q28580341 | RGS2 is a primary terminator of β₂-adrenergic receptor-mediated G(i) signaling |
| Q39084425 | RGS2 regulates urotensin II-induced intracellular Ca2+ elevation and contraction in glomerular mesangial cells. |
| Q36597655 | RGS2 squelches vascular Gi/o and Gq signaling to modulate myogenic tone and promote uterine blood flow |
| Q38960056 | RGS2 suppresses breast cancer cell growth via a MCPIP1-dependent pathway. |
| Q43169685 | RGS2-deficient mice exhibit decreased intraocular pressure and increased retinal ganglion cell survival |
| Q45109515 | RGS2-mediated regulation of Gqalpha |
| Q35067290 | RGS2: a "turn-off" in hypertension |
| Q33848879 | RGS4, a GTPase activator, improves renal function in ischemia–reperfusion injury |
| Q46799609 | RGS5, RGS4, and RGS2 expression and aortic contractibility are dynamically co-regulated during aortic banding-induced hypertrophy |
| Q34287867 | Regulation of Gβγi-dependent PLC-β3 activity in smooth muscle: inhibitory phosphorylation of PLC-β3 by PKA and PKG and stimulatory phosphorylation of Gαi-GTPase-activating protein RGS2 by PKG. |
| Q35700543 | Regulation of Renal Hemodynamics and Function by RGS2. |
| Q37726377 | Regulation of immune function by G protein-coupled receptors, trimeric G proteins, and RGS proteins. |
| Q42470364 | Regulation of intracellular Ca2+ release in corpus cavernosum smooth muscle: synergism between nitric oxide and cGMP. |
| Q64081493 | Regulator of G Protein Signaling 2 Facilitates Uterine Artery Adaptation During Pregnancy in Mice |
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| Q35087035 | Regulator of G protein signaling 2 is a functionally important negative regulator of angiotensin II-induced cardiac fibroblast responses |
| Q38765048 | Regulator of G protein signaling 2 is a key regulator of pancreatic β-cell mass and function |
| Q28594677 | Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice |
| Q56981988 | Regulator of G protein signalling 2 ameliorates angiotensin II-induced hypertension in mice |
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| Q82437098 | Regulator of G-protein signaling 2 (RGS2) inhibits androgen-independent activation of androgen receptor in prostate cancer cells |
| Q34896795 | Regulator of G-protein signaling 4 suppresses LPS-induced MUC5AC overproduction in the airway. |
| Q36465333 | Regulator of G-protein signalling 2 mRNA is differentially expressed in mammary epithelial subpopulations and over-expressed in the majority of breast cancers |
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| Q39899161 | Regulators of G-protein signalling are modulated by bacterial lipopeptides and lipopolysaccharide. |
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| Q34456993 | Renal Actions of RGS2 Control Blood Pressure |
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| Q36540310 | Rgs5 targeting leads to chronic low blood pressure and a lean body habitus |
| Q42220183 | Role of Cholinergic Innervation and RGS2 in Atrial Arrhythmia. |
| Q46425807 | SIRT1, heme oxygenase-1 and NO-mediated vasodilation in a human model of endogenous angiotensin II type 1 receptor antagonism: implications for hypertension |
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