scholarly article | Q13442814 |
P2093 | author name string | H Band | |
M Park | |||
T M Fournier | |||
L Lamorte | |||
C R Maroun | |||
M Lupher | |||
W Langdon | |||
P2860 | cites work | Fyn associates with Cbl and phosphorylates tyrosine 731 in Cbl, a binding site for phosphatidylinositol 3-kinase | Q22008672 |
A Grb2-associated docking protein in EGF- and insulin-receptor signalling | Q24321653 | ||
The Gab1 PH domain is required for localization of Gab1 at sites of cell-cell contact and epithelial morphogenesis downstream from the met receptor tyrosine kinase | Q24554529 | ||
v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas | Q24624849 | ||
Phosphotyrosine Binding Domain-Dependent Upregulation of the Platelet-Derived Growth Factor Receptor α Signaling Cascade by Transforming Mutants of Cbl: Implications for Cbl’s Function and Oncogenicity | Q24645473 | ||
Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase | Q27617539 | ||
Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase | Q27860571 | ||
The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase | Q28145635 | ||
Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7 | Q28146026 | ||
A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells | Q28289338 | ||
Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis | Q28295920 | ||
Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1 | Q29617290 | ||
c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor | Q29618661 | ||
An overview of epithelio-mesenchymal transformation | Q30014826 | ||
c-Cbl localizes to actin lamellae and regulates lamellipodia formation and cell morphology | Q30175270 | ||
Tyrosine phosphorylation of the product of the c-cbl protooncogene is [corrected] induced after integrin stimulation | Q30176698 | ||
Similarity of sli-1 , a Regulator of Vulval Development in C. elegans , to the Mammalian Proto-Oncogene c- cbl | Q30193172 | ||
The Cbl phosphotyrosine-binding domain selects a D(N/D)XpY motif and binds to the Tyr292 negative regulatory phosphorylation site of ZAP-70. | Q32170429 | ||
Alternative splicing generates isoforms of the met receptor tyrosine kinase which undergo differential processing | Q33263389 | ||
Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice | Q33776192 | ||
A direct interaction between the adaptor protein Cbl-b and the kinase zap-70 induces a positive signal in T cells | Q33854830 | ||
sli-1, a negative regulator of let-23-mediated signaling in C. elegans | Q33964849 | ||
DNA-mediated transfer of the adenine phosphoribosyltransferase locus into mammalian cells | Q34048204 | ||
Efficient Cellular Transformation by the Met Oncoprotein Requires a Functional Grb2 Binding Site and Correlates with Phosphorylation of the Grb2-associated Proteins, Cbl and Gab1 | Q34434226 | ||
Association of the Multisubstrate Docking Protein Gab1 with the Hepatocyte Growth Factor Receptor Requires a Functional Grb2 Binding Site Involving Tyrosine 1356 | Q34434985 | ||
Activation of cdc42, rac, PAK, and rho-kinase in response to hepatocyte growth factor differentially regulates epithelial cell colony spreading and dissociation | Q34712138 | ||
The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor alpha | Q36164471 | ||
Degradation of the Met tyrosine kinase receptor by the ubiquitin-proteasome pathway | Q36565319 | ||
Activation of both MAP kinase and phosphatidylinositide 3-kinase by Ras is required for hepatocyte growth factor/scatter factor-induced adherens junction disassembly | Q36899460 | ||
Growth factors and cell movement | Q37087094 | ||
Tumour induction by activated abl involves tyrosine phosphorylation of the product of the cbl oncogene | Q37636620 | ||
A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration | Q38334944 | ||
c-Cbl is downstream of c-Src in a signalling pathway necessary for bone resorption. | Q38352423 | ||
Isoforms of the met receptor tyrosine kinase | Q40851043 | ||
Tyrosine phosphorylation of C-Cbl facilitates adhesion and spreading while suppressing anchorage-independent growth of V-Abl-transformed NIH3T3 fibroblasts | Q40944647 | ||
Tyrosine kinase activity of the EGF receptor is enhanced by the expression of oncogenic 70Z-Cbl | Q41073646 | ||
Hepatocyte growth factor-induced scatter of Madin-Darby canine kidney cells requires phosphatidylinositol 3-kinase. | Q41270218 | ||
Epithelial-mesenchymal transitions in cancer progression | Q41449306 | ||
Model systems of epithelium-mesenchyme transitions | Q41449313 | ||
Receptor chimeras indicate that the met tyrosine kinase mediates the motility and morphogenic responses of hepatocyte growth/scatter factor. | Q41477545 | ||
The cell dissociation and motility triggered by scatter factor/hepatocyte growth factor are mediated through the cytoplasmic domain of the c-Met receptor | Q41532585 | ||
The Met receptor tyrosine kinase transduces motility, proliferation, and morphogenic signals of scatter factor/hepatocyte growth factor in epithelial cells | Q41563732 | ||
The Cbl protooncogene product: from an enigmatic oncogene to center stage of signal transduction. | Q41756552 | ||
Activation of nuclear factor of activated T cells-(NFAT) and activating protein 1 (AP-1) by oncogenic 70Z Cbl requires an intact phosphotyrosine binding domain but not Crk(L) or p85 phosphatidylinositol 3-kinase association | Q42467874 | ||
The Cbl protooncoprotein stimulates CSF-1 receptor multiubiquitination and endocytosis, and attenuates macrophage proliferation | Q42676655 | ||
Antisense repression of proto-oncogene c-Cbl enhances activation of the JAK-STAT pathway but not the ras pathway in epidermal growth factor receptor signaling | Q42802564 | ||
Efficient cell transformation by the Tpr-Met oncoprotein is dependent upon tyrosine 489 in the carboxy-terminus. | Q42830640 | ||
The proto-oncogene product p120(cbl) links c-Src and phosphatidylinositol 3'-kinase to the integrin signaling pathway. | Q45989111 | ||
Regulation of β1-integrin-mediated cell adhesion by the CbI adaptor protein | Q47849795 | ||
Tyrosine 1356 in the carboxyl-terminal tail of the HGF/SF receptor is essential for the transduction of signals for cell motility and morphogenesis | Q72809299 | ||
The product of the proto-oncogene c-cbl: a negative regulator of the Syk tyrosine kinase | Q73224118 | ||
The RING finger of c-Cbl mediates desensitization of the epidermal growth factor receptor | Q78069495 | ||
P433 | issue | 10 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 3397-3410 | |
P577 | publication date | 2000-10-01 | |
P1433 | published in | Molecular Biology of the Cell | Q2338259 |
P1476 | title | Cbl-transforming variants trigger a cascade of molecular alterations that lead to epithelial mesenchymal conversion | |
P478 | volume | 11 |
Q40559949 | A conserved DpYR motif in the juxtamembrane domain of the Met receptor family forms an atypical c-Cbl/Cbl-b tyrosine kinase binding domain binding site required for suppression of oncogenic activation. |
Q34405560 | Beyond the RING: CBL proteins as multivalent adapters |
Q37370673 | Cbl ubiquitination of p85 is essential for Epo-induced EpoR endocytosis |
Q38112644 | Cbl‐family proteins as regulators of cytoskeleton‐dependent phenomena |
Q27860487 | Epithelial-mesenchymal transitions in tumour progression |
Q34286540 | HGF and ligation of alphavbeta5 integrin induce a novel, cancer cell-specific gene expression required for cell scattering |
Q33314672 | Host-pathogen systems biology: logical modelling of hepatocyte growth factor and Helicobacter pylori induced c-Met signal transduction |
Q24681561 | LRIG1 is a novel negative regulator of the Met receptor and opposes Met and Her2 synergy |
Q37232416 | MET as a target for treatment of chest tumors |
Q38430194 | MET: a new promising biomarker in non-small-cell lung carcinoma |
Q58776408 | Molecular Signatures of the Insulin-like Growth Factor 1-mediated Epithelial-Mesenchymal Transition in Breast, Lung and Gastric Cancers |
Q35620884 | Molecular aspects of epithelial cell plasticity: implications for local tumor invasion and metastasis. |
Q28210330 | Mutation of the c-Cbl TKB domain binding site on the Met receptor tyrosine kinase converts it into a transforming protein |
Q34452683 | Negative regulation of EGFR-Vav2 signaling axis by Cbl ubiquitin ligase controls EGF receptor-mediated epithelial cell adherens junction dynamics and cell migration. |
Q28278555 | Prostate cancer and the met hepatocyte growth factor receptor |
Q40601255 | Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells |
Q33383797 | TEAD1 and c-Cbl are novel prostate basal cell markers that correlate with poor clinical outcome in prostate cancer. |
Q46476342 | The multidomain protooncogenic protein c-Cbl binds to tubulin and stabilizes microtubules |
Q33736621 | Ubiquitin ligase Cbl-b represses IGF-I-induced epithelial mesenchymal transition via ZEB2 and microRNA-200c regulation in gastric cancer cells |
Q33850376 | Valproic acid, targets papillary thyroid cancer through inhibition of c-Met signalling pathway |
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